The markets closed mixed with the Dow losing 22 points to 21,784 as the nation braces for Hurricane Irma. Nasdaq added 4 points to 6,397.

On the upside

Amcor is reportedly exploring a possible acquisition of Bemis (NYSE: BMS).

Guidewire Software (NYSE: GWRE) impressed with sharply higher fourth quarter earnings and revenue that surpassed analyst expectations.

AbbVie (NYSE: ABBV) reported positive results from a Phase 2b study of upadacitinib to treat moderate to severe atopic dermatitis.

On the downside

Insurers Aspen Insurance Holdings (NYSE: AHL), Everest Re Group (NYSE: RE) and Validus Holdings (NYSE: VR) all fell as Hurricane Irma approached Florida.

ABM Industries (NYSE: ABM) disappointed with third quarter earnings that fell short of expectations.

Comcast (Nasdaq: CMCSA) warned of significant subscriber losses in the third quarter.

In the broad market, advancing issues outpaced decliners by a margin of nearly 7 to 3 on the NYSE and by nearly 2 to 1 on Nasdaq. The broader S&P 500 held steady at 2,465. Bitcoin added $3 to $4,585.