Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
DUFFY MICHAEL P
   2. Issuer Name and Ticker or Trading Symbol
Lantheus Holdings, Inc. [LNTH] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
See Remarks
(Last)
(First)
(Middle)
C/O LANTHEUS HOLDINGS, INC., 331 TREBLE COVE ROAD		 3. Date of Earliest Transaction (Month/Day/Year)
01/10/2018
(Street)

NORTH BILLERICA, MA 01862		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 01/10/2018   M(1)   4,483 A $ 5.62 156,784 D  
Common Stock 01/10/2018   M(1)   17,172 A $ 5.62 173,956 D  
Common Stock 01/10/2018   S(1)   21,655 D $ 22.4018 (2) 152,301 D  

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (right to buy) $ 5.62 01/10/2018   M(1)     4,483   (3) 04/04/2018 Common Stock 4,483 $ 0 0 D  
Stock Option (right to buy) $ 5.62 01/10/2018   M(1)     17,172   (4) 04/04/2018 Common Stock 17,172 $ 0 0 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
DUFFY MICHAEL P
C/O LANTHEUS HOLDINGS, INC.
331 TREBLE COVE ROAD
NORTH BILLERICA, MA 01862		       See Remarks  

Signatures

 /s/ Michael P. Duffy   01/12/2018
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 12, 2017.
(2) The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $22.30 to $22.675, inclusive. The reporting person undertakes to provide to Lantheus Holdings, Inc., ("LNTH") any security holder of LNTH or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (2) to this Form 4.
(3) This option, originally representing a right to purchase a total of 44,483 shares of common stock, became exercisable in five equal annual installments beginning on April 4, 2009.
(4) This option, originally representing a right to purchase a total of 44,485 shares of common stock, became exercisable based on LNTH's satisfaction of certain performance criteria for each of the fiscal years ending 2008, 2009, 2010, 2011 and 2012. Certain of the performance criteria for 2008 and 2009 were met, resulting in the vesting of this option as to an aggregate of 17,172 shares of common stock.
 
Remarks:
SVP, General Counsel and Secretary

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