Tekla Healthcare Opportunities Fund Pays Distribution

On October 31, 2014, Tekla Healthcare Opportunities Fund paid a monthly stock distribution of $0.1125 per share. It is currently estimated that this distribution is derived from short-term capital gains. The composition of this and subsequent distribution may vary from month to month because it may be materially impacted by future realized gains and losses on securities. The aggregate of the net unrealized appreciation of portfolio securities and net realized gains on sale of securities is $38,859,279, of which $33,983,144 represents net unrealized appreciation of portfolio securities.

The following table sets forth the estimated amounts of the current distribution, payable October 31, 2014, and the cumulative distributions paid this fiscal year-to-date from the following sources: net investment income, net realized short-term capital gains, net realized long-term capital gains, and return of capital or other capital source. All amounts are expressed per common share.

The table below includes information relating to fund’s performance based on its NAV for certain periods.

You should not draw any conclusions about the Fund’s investment performance from the amount of this distribution or from the terms of the Fund’s managed distribution plan.

The amounts and sources of distributions reported in this 19(a) Notice are only estimates and are not being provided for tax reporting purposes. The actual amounts and sources of the amounts for tax reporting purposes will depend upon the Fund’s investment experience during the remainder of its fiscal year and may be subject to changes based on tax regulations. The Fund will send you a Form 1099-DIV for the calendar year that will tell you how to report these distributions for federal income tax purposes.

Tekla Healthcare Opportunities Fund (NYSE: THQ) is a closed-end fund that invests in companies in the healthcare industry.

Tekla Capital Management LLC, the Fund’s investment adviser, is a Boston, MA based healthcare-focused investment manager with approximately $2.3 billion of assets under management as of September 30, 2014. Tekla also serves as investment adviser to Tekla Healthcare Investors (NYSE: HQH) and Tekla Life Sciences Investors (NYSE: HQL), closed-end funds that invest in companies in the healthcare and life sciences industries. Information regarding the funds and Tekla Capital Management LLC can be found at www.teklacap.com.

Destra Capital Investments, the Fund’s marketing and investor support services agent, is a Lisle, IL based investment management firm. Please contact Destra Capital Investments at THQ@destracapital.com or call (877)855-3434 if you have any questions regarding THQ.

1 The Fund’s current fiscal year began on October 1, 2014.

2 Inception date was July 29, 2014, which is the date of the initial public offering.

3 Cumulative total return at NAV is the percentage change in the Fund’s NAV including distributions paid and assuming the reinvestment of those distributions for the period of July 29, 2014 through September 30, 2014.