The markets opened sharply lower with the Dow plunging 108 points to 17,840 as crude oil prices dropped. Nasdaq tumbled 42 points to 4,820.
On the upside
The Food and Drug Administration approved Insys' (Nasdaq: INSY) orally administered cannabis-based Syndros.
Leading Brands (Nasdaq: LBIX) entered an agreement to supply HappyWater to a significant customer in China.
Himax Technologies (Nasdaq: HIMX) announced that chief technology officer Chih-Chung Tsai has retired from his position and is not the vice chairman of company subsidiary Himax Technology Ltd.
On the downside
Amedica (Nasdaq: AMDA) priced its public offering of Class A units and Class B units to raise $11 million.
Profit taking weighed down shares of Harley-Davidson (NYSE: HOG).
Whiting Petroleum (NYSE: WLL) completed the exchange of $1.1 billion in convertible notes.
In the broad market, declining issues outpaced advancers by a margin of 7 to 2 on the NYSE and by more than 3 to 1 on Nasdaq. The broader S&P 500 tumbled 15 points to 2,087. Bitcoin lost $5 to $663.