Proceedings of the National Academy of Sciences has released a study finding that tumors change their genetic makeup to resist treatment, a find that may change cancer therapies.
Sarasota, USA - November 19, 2015 /PressCable/ —
State of the art research will likely change the focus of cancer therapy with a new discovery suggesting tumors may have an astonishing potential to adapt genetically — into diverse new entities — giving them the ability to resist current standard medical treatments.
Researchers concluded that miniscule tumors may be able to resist current modern treatments, such as postsurgical chemotherapy and radiation, by changing their cellular genetic make-up – an unprecedented discovery that is likely to change medical history.
The progressive study results, published in the Proceedings of the National Academy of Sciences, prompted study director, Chung-I Wu, professor of ecology and evolution at the University of Chicago, to address the astounding findings at the University’s official press release.
Wu explained the implications of the miraculous results, “In a setting with so much diversity, those cells could multiply to form new tumors, which would be resistant to standard treatments.
With 100 million mutations, each capable of altering a protein in some way, there is a high probability that a significant minority of tumor cells will survive, even after aggressive treatment.”
Research authors agree the new findings must influence current medical protocol in light of the discovery, saying, “The possibility of high intra-tumor diversity even in small tumors suggests a need to re-evaluate treatment strategies.” Research has found genetic mutations as tumors increase coincide with higher rates of cancer-related deaths as these mutations can become resistant to current cancer drugs.
The esteemed research used rigorous genetic sequencing methods on a human liver tumor and discovered over 100 million distinct genetic mutations within the coding of the tumor’s DNA – an astounding discovery for the scientists who had previously theorized a number thousands of times less than what they found.
Bob Mac, spokesperson for a natural health and wellness company, responded optimistically to the new discovery, saying, “The way the body communicates and functions on a cellular level is an exciting forefront emerging in modern research. The more science advances, the closer humankind will be toward conquering diseases such as cancer. With this new discovery, researchers can focus on effective cell apoptosis therapies — the mechanisms that cause cancer cells to self-destruct –leaving the healthy cells intact.”
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