Upbeat manufacturing activity data boosted the markets to a sharply higher close with the Dow leaping 152 points to 22,557. Nasdaq climbed 20 points to 6,516
On the upside
The Food and Drug Administration granted Breakthrough Therapy Designation to Seattle Genetics' (Nasdaq: SGEN) ADCETRIS in combination with chemotherapy for the frontline treatment of advanced classical Hodgkin lymphoma.
Olin (NYSE: OLN) lifted the Force Majeure that was declared on August 31, 2017.
A Barron's article made favorable comments about LiLAC Group (Nasdaq: LILAK).
On the downside
Morgan Stanley downgraded bluebird bio (Nasdaq: BLUE) from an Equal Weight rating to an Underweight rating.
Dentsply Sirona (Nasdaq: XRAY) chief executive Jeffrey Slovin, chief operating officer Christopher Clark and chairman Bret Wise have all resigned.
UBS downgraded HCP (NYSE: HCP) from a Neutral rating to a Sell rating.
The broader S&P 500 rose 9 points to 2,529. Bitcoin surged $77 to $4,400.