The Board of Directors of Macquarie Global Infrastructure Total Return Fund Inc. (NYSE:MGU) (the “Fund”) unanimously approved on September 8, 2010 a regular quarterly distribution for the period ending September 30, 2010 of $0.16 per share.

The Fund also announced that Andrew Maple-Brown, Portfolio Manager of the Fund, will host a quarterly investor conference call on Thursday, September 30, 2010 at 4:15 PM ET to discuss the Fund’s results for the quarter ended August 31, 2010.

“It was pleasing that the most recent Fund quarter saw good performance by the listed infrastructure sector,” said Mr. Maple-Brown. “This performance was supported by ongoing sound operational performance, as well as the emergence of corporate activity in the sector. The activity included potential transactions in the toll road sector for both Intoll and Abertis, as well as the announced sale by EDF of its regulated UK electricity distribution assets - all of which in our view demonstrate a recognition in the market of the value inherent within such infrastructure assets.”

Based on the Fund’s net asset value (“NAV”) of $19.12 and New York Stock Exchange closing market price of $16.20 on September 8, 2010, the $0.16 per share distribution is equal to an annualized distribution rate of 3.35% at NAV and 3.95% at market price, respectively.

A portion of the distributions may be treated as paid from sources other than net income, including, but not limited to, short-term capital gain, long-term capital gain and return of capital. The final determination of the source of all distributions in 2010, including the percentage of qualified dividend income, will be made by the Fund after December 31, 2010.

This distribution will be payable on September 30, 2010 to shareholders of record on September 23, 2010, with an ex-dividend date of September 21, 2010.

To listen to the quarterly investor conference call, please dial 1-877-407-0778 (domestic) or 1-201-689-8565 (international) at least 10 minutes prior to the scheduled start time and ask to be placed into the MGU Investor Call.

Interested parties can also listen to a live audio webcast of the call. The webcast will be accessible via http://www.investorcalendar.com/IC/CEPage.asp?ID=161492. Please allow extra time prior to the call to visit the site and register for the webcast.

A replay will be available following the call’s conclusion through October 30, 2010, at 1-877-660-6853 (domestic) or 1-201-612-7415 (international), Account Number: 286, Conference ID: 196074. An online archive of the webcast will also be available on the MGU website through October 30, 2010.

About the Macquarie Global Infrastructure Total Return Fund Inc.

Macquarie Global Infrastructure Total Return Fund Inc., a non-diversified closed-end fund, is listed on the NYSE.

The Fund’s investment adviser is Macquarie Capital Investment Management LLC, which is a part of Macquarie Funds Group and a wholly-owned, indirect subsidiary of Macquarie Group Limited.

Past performance is no assurance of future results. Investment return and market value of an investment in the Fund will fluctuate. Shares, when sold, may be worth more or less than their original costs. An investor should consider investment objectives, risks, charges and expenses carefully before investing. Forward-looking statements are based on information that is available on the date hereof, and neither the Investment Adviser nor any other person affiliated with the Investment Adviser has any duty to update any forward-looking statements. Important factors that could affect actual results to differ from these statements include, among other factors, material, negative changes to the asset class and the actual composition of the portfolio.

Investments in the Fund are not deposits with or other liabilities of Macquarie Bank Limited ABN 46 008 583 542 (“MBL”) nor any Macquarie Group company and are subject to investment risk, including possible delays in repayment and loss of income and principal invested. Neither MBL nor any other member company of the Macquarie Group guarantees the performance of the Fund or the repayment of capital from the Fund or any particular rate of return.