Hythiam Announces Presentation at Rodman & Renshaw 5th Annual Global Healthcare Conference in Monaco

Hythiam, Inc. (NASDAQ:HYTM) announced today that the Company will present at the upcoming Rodman & Renshaw 5th Annual Global Healthcare Conference to be held May 19-20, 2008, at the Le Meridien Beach Plaza Hotel in Monte Carlo, Monaco.

Terren Peizer, Chairman and Chief Executive Officer of Hythiam, will present Monday, May 19, at 5:15 PM (GMT+1). The presentation will be available as a live, audio webcast at: http://wsw.com/webcast/rrshq13/hytm. Hythiam's webcast will also be available on its website at www.hythiam.com, where it will be archived for 14 days following the conference.

About Hythiam®

Hythiam, Inc. provides behavioral health management services to health plans, employers, criminal justice, and government agencies through a network of licensed and company managed healthcare providers. The company approaches the management of behavioral health disorders with a focus on using the latest medical and health technology towards improved outcomes and out-patient treatment. Hythiam also researches, develops, licenses and commercializes innovative and proprietary physiological, nutritional, and behavioral treatment programs. Hythiam offers disease management for substance dependence built around its patented PROMETA Treatment Program for alcoholism and dependence to stimulants. The PROMETA Treatment Program, which integrates behavioral, nutritional, and medical components, is available only through licensed treatment providers and company managed treatment centers. Hythiam does not practice medicine or manufacture, distribute, or sell any medications and has no relationship with any manufacturers or distributors of medications used in the PROMETA Treatment Program. For further information, please visit www.hythiam.com.

Forward-Looking Statements

Except for statements of historical fact, the matters discussed in this press release are forward looking and made pursuant to the Safe Harbor provisions of the Private Securities Litigation Reform Act of 1995. These forward-looking statements reflect numerous assumptions and involve a variety of risks and uncertainties, many of which are beyond the company's control that may cause actual results to differ materially from stated expectations. These risk factors include, among others, limited operating history and lack of statistically significant formal research studies, the risk that treatment protocols might not be effective, difficulty in developing, exploiting and protecting proprietary technologies, intense competition and substantial regulation in the healthcare industry; and additional risks factors as discussed in the reports filed by the company with the Securities and Exchange Commission, which are available on its website at http://www.sec.gov.

Contacts:

for Hythiam, Inc.
Investor Relations:
In-Site Communications, Inc.
Lisa M. Wilson, 212-759-3929
lwilson@insitecony.com
or
Media Relations:
Dan Klores Communications
Tim Sullivan, 212-981-5234
tim_sullivan@dkcnews.com

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