The markets closed lower with the Dow losing 13 points to 20,650 as manufacturing activity expansion slowed in March. Nasdaq fell 17 points to 5,894.
On the upside
Brainstorm Cell Therapeutics (Nasdaq: BCLI) stock extended its gains.
Wix.com (Nasdaq: WIX) climbed for the second day.
The European Patent Office issued a notice of Intent to Grant to Cellect Biotechnology (Nasdaq: APOP) for a patent covering a key method of treatment.
On the downside
Shares of Acorda Therapeutics (Nasdaq: ACOR) extended its losses.
Investors locked in profits on Hertz Global (NYSE: HTZ).
Orexigen Therapeutics (Nasdaq: OREX) stock fell for the third day.
In the broad market, declining issues outpaced advancers by a margin of 5 to 4 on the NYSE and by 5 to 2 on Nasdaq. The broader S&P 500 index lost 3 points to 2,358. Bitcoin surged $52 to $1142.
