On the upside
Align Technology (Nasdaq: ALGN) settled a patent suit against Ormco, a subsidiary of Danaher Corporation (NYSE: DHR) and plan to collaborate on its orthodontic Invisalign product.
BioSante Pharmaceuticals (Nasdaq: BPAX) announced that its drug strengthened the efficacy of flu vaccines in animal tests.
On the downside
Lowe's (NYSE: LOW) posted revenues and earnings that fell and missed expectations due to slow consumer spending and inclement weather.
Shares of InterDigital (Nasdaq: IDCC) tumbled after the U.S. International Trade Commission ruled in Nokia's (NYSE: NOK) favor on a handset patent dispute.
Rosetta Stone (NYSE: RST) lowered its 3rd quarter profit guidance and cancelled a stock offering announced a week ago. The stock made its debut in April 2009.
AEterna Zentaris (Nasdaq: AEZS) reported disappointing Phase 3 results for its prostate and urinary disease drug treatement. The stock promptly sold off.
In the broad market, declining issues overwhelmed advancers by a margin of nearly 10 to 1 on the NYSE and by more than 6 to 1 on Nasdaq. The Russell 2000 which tracks small cap stocks dropped 12 points to 551.