The Dow closed above the 22,000 mark for the very first time by gaining 52 points to 22,016 on upbeat earnings news. Nasdaq held steady at 6,362.
On the upside
Spark Therapeutics (Nasdaq: ONCE) submitted a Marketing Authorization Application to the European Medicines Agency for LUXTURNA.
Illumina (Nasdaq: ILMN) reported higher second quarter earnings and revenue that surpassed expectations.
Intrepid Potash (NYSE: IPI) narrowed losses for the second quarter.
On the downside
Unisys (NYSE: UIS) fell to a loss for the second quarter as revenue dropped.
Radisys (Nasdaq: RSYS) widened second quarter losses, warned of losses for the third quarter and cut its full year revenue guidance.
Third quarter earnings and revenue surged for Coherent (Nasdaq: COHR) but the results missed expectations.
In the broad market, declining issues outpaced advancers by a margin of more than 3 to 2 on the NYSE and by more than 7 to 3 on Nasdaq. The broader S&P 500 added a point to 2,477. Bitcoin tumbled $32 to $2602.