Mixed open as crude oil falls

The markets opened mixed with the Dow losing 24 points to 19,191 as crude oil prices slipped. Nasdaq edged up a fraction to 5,309.


On the upside


Neovasc (Nasdaq: NVCN) reported an 86% successful implantation rate for its Tiara transcatheter mitral valve.


Heat Biologics (Nasdaq: HTBX) reported positive data from an ongoing Phase 1 study of its non-small cell lung cancer treatment HS-110.


Francesca's Holdings (Nasdaq: FRAN) reported higher third quarter earnings and revenue.


On the downside


Investors locked in profits on Vanguard Natural Resources (Nasdaq: VNR).


Synchronoss Technologies (Nasdaq: SNCR) will pay a premium of approximately $821 million to acquire Intralinks Holdings (NYSE: IL).


Safe Bulkers (NYSE: SB) priced its public offering of 13.6 million common shares at the discounted price of $1.10 per share.


In the broad market, advancing issues outpaced decliners by a margin of nearly 10 to 9 on the NYSE while decliners barely edged out advancers by a slim margin on Nasdaq. The broader S&P 500 index slipped 2 points to 2,202. Bitcoin rose $3 to $756.


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