Mixed close on continued interest rate hikes

The markets closed mixed with the Dow slipping 11 points to 22,284 while Nasdaq rose 9 points to 6,380 after Federal Reserve chair Janet Yellen said that interest rates must continue rising gradually.

On the upside

Greenhill (NYSE: GHL) announced plans to repurchase up to $235 million worth of common stock.

Actua (Nasdaq: ACTA) will sell three majority owned businesses for $549 million in cash.

Palmetto GBA's Molecular Diagnostics Service set the reimbursement for CareDx's (Nasdaq: CDNA) AlloSure cfDNA-based organ transplant test diagnostic at $2,840.75.

On the downside

Kadmon Holdings (NYSE: KDMN) announced a public offering of common stock and warrants.

QEP Resources (NYSE: QEP) cut its full year production outlook prompting Stifel to lower its price target on the energy company from $26.00 to $23.00.

Shares of Twilio (NYSE: TWLO) fell over concerns that Amazon's (Nasdaq: AMZN) new AWS Global SMS two-way text messaging would steal its customers.

In the broad market, advancing issues outpaced advancers by a margin of nearly 4 to 3 on the NYSE and by more than 4 to 3 on Nasdaq. The broader S&P 500 held steady at 2,496. Bitcoin lost $15 to $3,922.