The markets closed lower with the Dow losing 15 points to 20,934 as investors locked in profits from yesterday's rally. Nasdaq held steady at 5,900.
On the upside
Shares of Canada Goose Holdings (NYSE: GOOS) soared in its market debut.
Innocoll Holdings (Nasdaq: INNL) confirmed that the company was engaged in discussions for a potential sale of the company.
Seres Therapeutics (NYSE: MCRB) will initiate a new SER-109 clinical study in patients with multiply recurrent Clostridium difficile infection.
On the downside
TrovaGene (Nasdaq: TROV) widened fourth quarter losses more than expected.
Arotech (Nasdaq: ARTX) fell to a loss for the fourth quarter.
PTC Therapeutics (Nasdaq: PTCT) will pay approximately $75 million in cash and $65 million in stock to purchase Marathon Pharmaceuticals' Duchenne muscular dystrophy treatment Emflaza.
In the broad market, advancing issues outpaced decliners by a margin of nearly 9 to 7 on the NYSE and by more than 7 to 5 on Nasdaq. The broader S&P 500 index lost 3 points to 2,381. Bitcoin tumbled $21 to $1,220.