The markets closed lower with the Dow dropping 54 points to 15,413 over disappointing earnings. Nasdaq fell 22 points to 3907.
On the upside
Medivation (Nasdaq: MDVN) reported upbeat results from a Phase 3 PREVAIL trial of its prostate cancer treatment enzalutamide.
Bargain hunters lifted shares of J. C. Penney (NYSE: JCP).
Boeing (NYSE: BA) reported higher third quarter earnings and revenue that beat analyst expectations.
On the downside
Ziopharm (Nasdaq: ZIOP) will offer $50 million worth of common stock.
Gigamon (NYSE: GIMO) priced its follow-on offering of 5.1 million common shares at the discounted price of $38.50.
Juniper Networks (NYSE: JNPR) reported sharply higher third quarter earnings but investors were disappointed with the company's outlook.
In the broad market, declining issues outpaced advancers by a margin of nearly 5 to 4 on the NYSE and by 3 to 2 on Nasdaq. The broader S&P 500 lost 8 points to 1746.