Tekla Healthcare Opportunities Fund Pays Distribution

On September 30, 2014, Tekla Healthcare Opportunities Fund paid a monthly stock distribution of $0.1125 per share. It is currently estimated that this distribution is derived from short-term capital gains. The composition of this and subsequent distributions may vary from month to month because it may be materially impacted by future realized gains and losses on securities. The aggregate of the net unrealized appreciation of portfolio securities and net realized gains on the sale of securities is $32,241,221, of which $24,873,321 represents net unrealized appreciation of portfolio securities.

The amounts and sources of distributions reported in this notice are only estimates and are not being provided for tax reporting purposes. The actual amounts and sources of the amounts for tax reporting purposes will depend upon the Fund’s investment activity through December 31, 2014, and may be subject to changes based on the tax regulations. Shareholders will receive a Form 1099-DIV in early 2015 notifying them of the sources of all distributions for calendar year 2014 for federal income tax purposes.

Tekla Healthcare Opportunities Fund (NYSE: THQ) is a closed-end fund that invests in companies in the healthcare industry.

Tekla Capital Management LLC, the Fund’s investment adviser, is a Boston, MA based healthcare-focused investment manager with approximately $2 billion of assets under management as of July 31, 2014. Tekla also serves as investment adviser to H&Q Healthcare Investors (NYSE: HQH) and H&Q Life Sciences Investors (NYSE: HQL), closed-end funds that invest in companies in the healthcare and life sciences industries. Information regarding the funds and Tekla Capital Management LLC can be found at www.teklacap.com.

Destra Capital Investments, the Fund’s marketing and investor support services agent, is a Lisle, IL based investment management firm. Please contact Destra Capital Investments at THQ@destracapital.com or call (877)855-3434 if you have any questions regarding THQ.