China Team is First to Inject CRISPR-edited Genes into Human

A team led by Lu You, an oncologist at Chengdu's Sichuan University, became the first to inject CRISPR–Cas9 edited genes into a patient. The patient has metastatic non-small cell lung cancer. The team extracted immune cells from the unnamed person, used CRISPR–Cas9 editing tools to delete the PD-1 immune system checkpoint, expanded the edited cells and injected them back into the patient. The ten-patient trial will administer two, three and four rounds of the treatment, with safety being the primary endpoint, though everyone will be equally interested in any signs of efficacy. More details.... Share this with colleagues: // //