New York, US - Jan 23, 2019 - Creative Biolabs is a well-established company that specializes in offering the superb phage library screening service for its clients around the globe. With the help of this striking service, consumers will be able to achieve their various project objectives.
Phage display is a powerful laboratory technique widely used for the study of protein-protein, protein-peptide and protein-DNA interactions. Specifically, after the gene coding proteins is inserted into a phage coat protein gene, the phage “displays” the protein on its outside while the protein gene remains inside, thereby resulting in a connection between genotype and phenotype. The displayed phages can be screened against other proteins, peptide or DNA sequences, so as to detect interaction between the displayed protein and other molecules. Hence, phage library screening has been considered an extremely useful technique for the enrichment and identification of binders with high affinity and specificity in libraries of interest.
“Phage display technology has emerged as one of the principal approaches applied to a wide range of protein interaction studies, particularly to the discovery of specific antibodies, scaffolds or ligands. That’s why we value this technology very much. Through years of development, our display service makes it possible to make biopanning strategies tailored to the clients’ diverse requirements. Generally, we are able to select scFv or Fab antibodies with the affinity of 10-7. Besides, the sub-libraries of the isolated scFv or Fab antibodies enable us to increase the affinity from 10-8 to 10-9. So far, our company has managed to obtain a scFv antibody with an affinity of up to 10-12. There exist several methods for library screening. The most common approach is solid-phase screening, adopted to select binders against specific targets adsorbed onto a solid surface. Solution-sorting screening serves as an ideal approach to antibody selection, and cell-base screening finds its use particularly in cell surface antigen selection. In a word, many approaches have been available here to fulfill a variety of market demands,” a scientist from Creative Biolabs said.
In order to optimize its phage display library screening service, the company also offers proprietary phage display libraries. Its phage library construction portfolio covers the scaffold library, naïve or semi-syntheticpeptide library, cDNA library, etc. To sum up, it offers a comprehensive list of phage display libraries to improve its phage library screening service. Thus, there’s every reason to believe that its screening service will satisfy different requirements of its customers for biopanning.
About Creative Biolabs
Creative Biolabs is a leading custom service provider, with abundant experience in antibody production and engineering. Its service covers murine, human, monkey, rabbit, chicken, dog, llama and camel monoclonal antibody production. The company also conducts in-depth antibody humanization and affinity maturation using phage display and DNA mutagenesis approaches.
Media Contact
Company Name: Creative Biolabs
Contact Person: Candy Swift
Email: Send Email
Phone: 1-631-619-7922
Address:45-1 Ramsey Road
City: Shirley
State: New York
Country: United States
Website: www.creative-biolabs.com/
Source: www.abnewswire.com
