Lower close ahead of payrolls report

The markets closed lower with the Dow losing 31 points to 17,685 ahead of the March payrolls report tomorrow. Nasdaq held steady at 4,869.


On the upside


Genocea Biosciences (Nasdaq: GNCA) reported positive 12-month efficacy data from a Phase 2 trial of GEN-003 to treat genital herpes.


Reuters reported that Medivation (Nasdaq: MDVN) engaged in discussions with JPMorgan Chase to explore a possible sale of the company.


Sky Solar Holdings (Nasdaq: SKYS) narrowed losses for the fourth quarter as revenue soared.


On the downside


aTyr Pharma (Nasdaq: LIFE) widened losses as expenses surged.


Anacor Pharmaceuticals (Nasdaq: ANAC) will offer $250 million in convertible senior notes.


Silver Wheaton (NYSE: SLW) entered a $500 million bought deal financing with RBC Capital Markets, BMO Capital Markets, CBIC Capital Markets and Scotiabank.


In the broad market, advancing issues outpaced decliners by a margin of nearly 3 to 2 on the NYSE and by more than 9 to 7 on Nasdaq. The broader S&P 500 lost 4 points to 2,059. Bitcoin added $2 to $415.

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