FORM 5 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b). Form 3 Holdings Reported Form 4 Transactions Reported

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 ANNUAL STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person * RALES MITCHELL P 2. Issuer Name and Ticker or Trading Symbol DANAHER CORP /DE/ [DHR] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director _____ 10% Owner __X__ Officer (give title below) _____ Other (specify below) Chairman of Exec. Committee (Last) (First) (Middle) 11790 GLEN ROAD 3. Statement for Issuer's Fiscal Year Ended (Month/Day/Year) 12/31/2018 (Street) POTOMAC, MD 20854 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Reporting (check applicable line) _X_ Form Filed by One Reporting Person ___ Form Filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned at end of Issuer's Fiscal Year (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Amount (A) or (D) Price Common Stock, par value $.001 02/02/2018   G 150,000 D $ 0 2,147,673 D   Common Stock, par value $.001 02/12/2018   G 17,442 D $ 0 2,130,231 D   Common Stock, par value $.001 02/12/2018   G 17,442 A $ 0 692,151 I Through the Mitchell P. Rales Family Trust (1) Common Stock, par value $.001 05/02/2018   G 102,278 D $ 0 2,027,953 D   Common Stock, par value $.001 05/02/2018   G 102,278 A $ 0 794,429 I Through the Mitchell P. Rales Family Trust (1) Common Stock, par value $.001 07/24/2018   G 200,000 D $ 0 1,827,953 D   Common Stock, par value $.001 10/19/2018   G 400,000 D $ 0 3,427,953 (2) D   Common Stock, par value $.001 10/25/2018   G 200,000 D $ 0 3,227,953 D   Common Stock, par value $.001 11/09/2018   G 200,000 D $ 0 3,027,953 D   Common Stock, par value $.001             32,000,000 (2) I Through single-member LLCs (3) Common Stock, par value $.001             25,660 I By Spouse (4) Common Stock, par value $.001             295 I By daughter (5) Common Stock, par value $.001             295 I By daughter (5) Common Stock, par value $.001             193,431 I By 401(k) Plan

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

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SEC 2270 (9-02)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned at End of Issuer's Fiscal Year (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
RALES MITCHELL P 11790 GLEN ROAD POTOMAC, MD 20854	  X	Â	  Chairman of Exec. Committee	Â

Signatures

/s/ Mitchell P. Rales		01/29/2019
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	The Reporting Person is the trustee of the Mitchell P. Rales Family Trust.
(2)	Total reflects a change in form of ownership pursuant to the exemption provided by Rule 16a-13 under the Securities Exchange Act of 1934, as amended.
(3)	The reported shares are held through single-member LLCs, of which a revocable trust with the Reporting Person as the sole trustee and beneficiary is the sole member of these LLCs.
(4)	The Reporting Person disclaims beneficial ownership of the shares held by his spouse, and this report should not be deemed an admission that the Reporting Person is the beneficial owner of his spouse's shares for purposes of Section 16 or for any other purpose.
(5)	The reported shares are held through custodial accounts for the benefit of the Reporting Person's daughter. The Reporting Person disclaims beneficial ownership of the shares held by his daughter, and this report should not be deemed an admission that the Reporting Person is the beneficial owner of his daughter's shares for purposes of Section 16 or for any other purpose.

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