UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 8-K

Current Report Pursuant
to Section 13 or 15(d) of the
Securities Exchange Act of 1934

Date of Report (Date of earliest event reported):  April 22, 2010

WESTERN ALLIANCE BANCORPORATION
(Exact name of registrant as specified in its charter)

Registrant’s telephone number, including area code: (702) 248-4200

Not Applicable
(Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

⃞ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

⃞ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

⃞ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

⃞ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) under the Exchange Act (17 CFR 240.13e-4(c)) Rule 425, Rule 14a-12 and Instruction 2 to Rule 14d-2(b) (2)

Item 2.02. Results of Operations and Financial Condition.

On April 22, 2010, Western Alliance Bancorporation issued a press release describing its results of operations for the first quarter of 2010. That press release is attached hereto as Exhibit 99.1.

Item 8.01. Other Events.

On April 21, 2010, Western Alliance Bancorporation (the “Company”) entered into a stock purchase agreement pursuant to which the Company has agreed to sell its entire equity interest in Premier Trust, Inc. to an unrelated party. The closing of the transaction, which is subject to customary conditions, is expected to occur in the second quarter of 2010.  The Company’s bank affiliates will continue to provide banking services to Premier Trust, Inc. and a number of its clients.

Item 9.01. Financial Statements and Exhibits. (c) Exhibits.

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.