SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  Schedule 13G


  INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1 (b), 
         (c) AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO 13d-2 (b)
                              (Amendment No. ___)*

                                NeuroMetrix, Inc.
--------------------------------------------------------------------------------
                                (Name of Issuer)

                                  Common Stock
--------------------------------------------------------------------------------
                         (Title of Class of Securities)

                                    641255104
--------------------------------------------------------------------------------
                                 (CUSIP Number)

                                December 31, 2004
--------------------------------------------------------------------------------
             (Date of Event Which Requires Filing of this Statement)

Check the  appropriate box to designate the rule pursuant to which this Schedule
is filed:

         [ ]         Rule 13d-1(b)

         [ ]         Rule 13d-1(c)

         [X]         Rule 13d-1(d)

*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for  any  subsequent   amendment   containing   information  which  would  alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).

                         (Continued on following pages)


                               Page 1 of 14 Pages
                            Exhibit Index on Page 13



----------------------------------- ------------------- ------------------------
CUSIP NO. 641255104                        13 G               Page 2 of 14 Pages
----------------------------------- ------------------- ------------------------

------------ -------------------------------------------------------------------

1            NAME OF REPORTING
             SS OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
                      Delphi Ventures IV, L.P. ("DV IV")
                      Tax ID Number:
------------ -------------------------------------------------------------------
2            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
                                                                               
                                                                (a)  [ ] (b) [X]
------------ -------------------------------------------------------------------

3            SEC USE ONLY
------------ -------------------------------------------------------------------

4            CITIZENSHIP OR PLACE OF ORGANIZATION
                      Delaware
------------------------------------ -------- ----------------------------------
                      5      SOLE VOTING POWER
   NUMBER OF                 871,415  shares,   except  that  Delphi  Management
    SHARES                   Partners IV, L.L.C. ("DMP IV"), the general partner
 BENEFICIALLY                of DV IV,  may be deemed to have sole power to vote
 OWNED BY EACH               these    shares,    and    James   J.    Bochnowski
   REPORTING                 ("Bochnowski"),  David L. Douglass ("Douglass") and
    PERSON                   Donald J. Lothrop ("Lothrop"), the managing members
     WITH                    of DMP IV,  may be deemed to have  shared  power to
                             vote these shares.
                      ------ ---------------------------------------------------
                      6      SHARED VOTING POWER
                             See response to row 5.
                      ------ ---------------------------------------------------
                      7      SOLE DISPOSITIVE POWER
                             871,415  shares,  except  that DMP IV, the  general
                             partner  of DV IV, may be deemed to have sole power
                             to  dispose  of  these  shares,   and   Bochnowski,
                             Douglass and Lothrop,  the managing  members of DMP
                             IV, may be deemed to have  shared  power to dispose
                             of these shares.
                             -------- ------------------------------------------
                      8      SHARED DISPOSITIVE POWER
                             See response to row 7.
------------ -------------------------------------------------------------------
9            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
             REPORTING PERSON                                          871,415
------------ -------------------------------------------------------------------
10           CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
             EXCLUDES CERTAIN SHARES                                    [ ]
------------ -------------------------------------------------------------------
11           PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
                                                                       7.2%
------------ -------------------------------------------------------------------
12           TYPE OF REPORTING PERSON
                                                                       PN
------------ -------------------------------------------------------------------



----------------------------------- ------------------- ------------------------
CUSIP NO. 641255104                        13 G               Page 3 of 14 Pages
----------------------------------- ------------------- ------------------------

------------ -------------------------------------------------------------------

1            NAME OF REPORTING
             SS OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
                      Delphi BioInvestments IV, L.P. ("DBI IV")
                      Tax ID Number:
------------ -------------------------------------------------------------------
2            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
                                                                                
                                                                (a)  [ ] (b) [X]
------------ -------------------------------------------------------------------
3            SEC USE ONLY
------------ -------------------------------------------------------------------
4            CITIZENSHIP OR PLACE OF ORGANIZATION
                      Delaware
------------------------------------ -------- ----------------------------------
                      5      SOLE VOTING POWER
   NUMBER OF                 17,965  shares,  except  that DMP IV,  the  general
    SHARES                   partner of DBI IV, may be deemed to have sole power
 BENEFICIALLY                to vote  these  shares,  and  Bochnowski,  Douglass
 OWNED BY EACH               and Lothrop,  the managing  members of DMP IV,  may
   REPORTING                 be  deemed  to  have  shared  power  to  vote these
    PERSON                   shares.
     WITH             ------ ---------------------------------------------------
                      6      SHARED VOTING POWER
                             See response to row 5.
                      ------ ---------------------------------------------------
                      7      SOLE DISPOSITIVE POWER
                             17,965  shares,  except  that DMP IV,  the  general
                             partner of DBI IV, may be deemed to have sole power
                             to  dispose  of  these  shares,   and   Bochnowski,
                             Douglass and Lothrop,  the managing  members of DMP
                             IV, may be deemed to have  shared  power to dispose
                             of these shares.
                      ------ ---------------------------------------------------
                      8      SHARED DISPOSITIVE POWER
                             See response to row 7.
------------ -------------------------------------------------------------------
9            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
             REPORTING PERSON                                       17,965
------------ -------------------------------------------------------------------
10           CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
             EXCLUDES CERTAIN SHARES                                 [ ]
------------ -------------------------------------------------------------------
11           PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
                                                                    0.1%
------------ -------------------------------------------------------------------
12           TYPE OF REPORTING PERSON
                                                                    PN
------------ -------------------------------------------------------------------



----------------------------------- ------------------- ------------------------
CUSIP NO. 641255104                        13 G               Page 4 of 14 Pages
----------------------------------- ------------------- ------------------------

------------ -------------------------------------------------------------------
1            NAME OF REPORTING
             SS OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
                      Delphi Management Partners IV, L.L.C. ("DMP IV")
                      Tax ID Number:
------------ -------------------------------------------------------------------
2            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
                                                                                
                                                                (a)  [ ] (b) [X]
------------ -------------------------------------------------------------------
3            SEC USE ONLY
------------ -------------------------------------------------------------------
4            CITIZENSHIP OR PLACE OF ORGANIZATION
                      Delaware
------------------------------------ -------- ----------------------------------
                      5      SOLE VOTING POWER
   NUMBER OF                 889,380 shares, of which 871,415 are directly owned
    SHARES                   by DV IV and 17,965 are  directly  owned by DBI IV.
 BENEFICIALLY                DMP IV,  the  general  partner of DV IV and DBI IV,
 OWNED BY EACH               may be  deemed  to have  sole  power to vote  these
   REPORTING                 shares, and Bochnowski,  Douglass and Lothrop,  the
    PERSON                   managing  members  of DMP IV, may be deemed to have
     WITH                    shared power to vote these shares.
                      ------ ---------------------------------------------------
                      6      SHARED VOTING POWER
                             See response to row 5.
                      ------ ---------------------------------------------------
                      7      SOLE DISPOSITIVE POWER
                             889,380 shares, of which 871,415 are directly owned
                             by DV IV and 17,965 are  directly  owned by DBI IV.
                             DMP IV,  the  general  partner of DV IV and DBI IV,
                             may be  deemed  to have sole  power to  dispose  of
                             these shares, and Bochnowski, Douglass and Lothrop,
                             the  managing  members  of DMP IV, may be deemed to
                             have shared power to dispose of these shares.
                      ------ ---------------------------------------------------
                      8      SHARED DISPOSITIVE POWER
                             See response to row 7.
------------ -------------------------------------------------------------------
9            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
             REPORTING PERSON                                       889,380
------------ -------------------------------------------------------------------
10           CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
             EXCLUDES CERTAIN SHARES                                 [ ]
------------ -------------------------------------------------------------------
11           PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
                                                                    7.4%
------------ -------------------------------------------------------------------
12           TYPE OF REPORTING PERSON
                                                                    OO
------------ -------------------------------------------------------------------



----------------------------------- ------------------- ------------------------
CUSIP NO. 641255104                        13 G               Page 5 of 14 Pages
----------------------------------- ------------------- ------------------------

------------ -------------------------------------------------------------------
1            NAME OF REPORTING
             SS OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
                      James J. Bochnowski ("Bochnowski")
                      Tax ID Number:
------------ -------------------------------------------------------------------
2            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
                                                                                
                                                                (a)  [ ] (b) [X]
------------ -------------------------------------------------------------------
3            SEC USE ONLY
------------ -------------------------------------------------------------------
4            CITIZENSHIP OR PLACE OF ORGANIZATION
                      U.S. Citizen
------------------------------------ -------- ----------------------------------
       NUMBER OF
        SHARES        5      SOLE VOTING POWER
     BENEFICIALLY            0 shares
     OWNED BY EACH
       REPORTING
        PERSON
         WITH         ------ ---------------------------------------------------
                      6      SHARED VOTING POWER
                             889,380 shares, of which 871,415 are directly owned
                             by DV IV and 17,965 are  directly  owned by DBI IV.
                             Bochnowski  is a  managing  member  of DMP IV,  the
                             general  partner  of DV IV and DBI  IV,  and may be
                             deemed to have shared power to vote these shares.
                      ------ ---------------------------------------------------
                      7      SOLE DISPOSITIVE POWER
                             0 shares
                      ------ ---------------------------------------------------
                      8      SHARED DISPOSITIVE POWER
                             889,380 shares, of which 871,415 are directly owned
                             by DV IV and 17,965 are  directly  owned by DBI IV.
                             Bochnowski  is a  managing  member  of DMP IV,  the
                             general  partner  of DV IV and DBI  IV,  and may be
                             deemed to have  shared  power to  dispose  of these
                             shares.
------------------------------------ -------- ----------------------------------
9            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
             REPORTING PERSON                                      889,380
------------ -------------------------------------------------------------------
10           CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
             EXCLUDES CERTAIN SHARES                                [ ]
------------ -------------------------------------------------------------------
11           PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
                                                                   7.4%
------------ -------------------------------------------------------------------
12           TYPE OF REPORTING PERSON
                                                                   IN
------------ -------------------------------------------------------------------



----------------------------------- ------------------- ------------------------
CUSIP NO. 641255104                        13 G               Page 6 of 14 Pages
----------------------------------- ------------------- ------------------------

------------ -------------------------------------------------------------------
1            NAME OF REPORTING
             SS OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
                      David L. Douglass ("Douglass")
                      Tax ID Number:
------------ -------------------------------------------------------------------
2            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
                                                                                
                                                                (a)  [ ] (b) [X]
------------ -------------------------------------------------------------------
3            SEC USE ONLY
------------ -------------------------------------------------------------------
4            CITIZENSHIP OR PLACE OF ORGANIZATION
             U.S. Citizen
------------------------------------ -------- ----------------------------------
     NUMBER OF
      SHARES          5      SOLE VOTING POWER
   BENEFICIALLY              0 shares
   OWNED BY EACH
     REPORTING
      PERSON
       WITH           -------- -------------------------------------------------
                      6      SHARED VOTING POWER
                             889,380 shares, of which 871,415 are directly owned
                             by DV IV and 17,965 are  directly  owned by DBI IV.
                             Douglass  is a  managing  member  of  DMP  IV,  the
                             general  partner  of DV IV and DBI  IV,  and may be
                             deemed to have shared power to vote these shares.
                      -------- -------------------------------------------------
                      7      SOLE DISPOSITIVE POWER
                             0 shares
                      -------- -------------------------------------------------
                      8      SHARED DISPOSITIVE POWER
                             889,380 shares, of which 871,415 are directly owned
                             by DV IV and 17,965 are  directly  owned by DBI IV.
                             Douglass  is a  managing  member  of  DMP  IV,  the
                             general  partner  of DV IV and DBI  IV,  and may be
                             deemed to have  shared  power to  dispose  of these
                             shares.
------------ -------------------------------------------------------------------
9            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
             REPORTING PERSON                                        889,380
------------ -------------------------------------------------------------------
10           CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
             EXCLUDES CERTAIN SHARES                                  [ ]
------------ -------------------------------------------------------------------
11           PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
                                                                     7.4%
------------ -------------------------------------------------------------------
12           TYPE OF REPORTING PERSON
                                                                     IN
------------ -------------------------------------------------------------------



----------------------------------- ------------------- ------------------------
CUSIP NO. 641255104                        13 G               Page 7 of 14 Pages
----------------------------------- ------------------- ------------------------

------------ -------------------------------------------------------------------
1            NAME OF REPORTING
             SS OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
                      Donald J. Lothrop ("Lothrop")
                      Tax ID Number:
------------ -------------------------------------------------------------------
2            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
                                                                                
                                                                (a)  [ ] (b) [X]
------------ -------------------------------------------------------------------
3            SEC USE ONLY
------------ -------------------------------------------------------------------
4            CITIZENSHIP OR PLACE OF ORGANIZATION
             U.S. Citizen
------------------------------------ -------- ----------------------------------
      NUMBER OF
       SHARES         5      SOLE VOTING POWER
    BENEFICIALLY             0 shares
    OWNED BY EACH
      REPORTING
       PERSON
        WITH          ------- --------------------------------------------------
                      6      SHARED VOTING POWER
                             889,380 shares, of which 871,415 are directly owned
                             by DV IV and 17,965 are  directly  owned by DBI IV.
                             Lothrop is a managing member of DMP IV, the general
                             partner  of DV IV and DBI IV,  and may be deemed to
                             have shared power to vote these shares.
                      ------- --------------------------------------------------
                      7      SOLE DISPOSITIVE POWER
                             0 shares
                      ------- --------------------------------------------------
                      8      SHARED DISPOSITIVE POWER
                             889,380 shares, of which 871,415 are directly owned
                             by DV IV and 17,965 are  directly  owned by DBI IV.
                             Lothrop is a managing member of DMP IV, the general
                             partner  of DV IV and DBI IV,  and may be deemed to
                             have shared power to dispose of these shares.
------------ -------------------------------------------------------------------
9            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
             REPORTING PERSON                                      889,380
------------ -------------------------------------------------------------------
10           CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
             EXCLUDES CERTAIN SHARES                                 [ ]
------------ -------------------------------------------------------------------
11           PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
                                                                   7.4%
------------ -------------------------------------------------------------------
12           TYPE OF REPORTING PERSON
                                                                   IN
------------ -------------------------------------------------------------------


                                                              Page 8 of 14 Pages

ITEM 1(A).        NAME OF ISSUER:
                  ---------------

                  NeuroMetrix, Inc.

ITEM 1(B).        ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES:
                  ------------------------------------------------

                  62 Fourth Avenue
                  Waltham, MA 02451

ITEM 2(A).        NAME OF PERSONS FILING:
                  -----------------------

                  This  statement  is filed  by  Delphi  Ventures  IV,  L.P.,  a
                  Delaware limited partnership ("DV IV"), Delphi  BioInvestments
                  IV, L.P., a Delaware limited  partnership  ("DBI IV"),  Delphi
                  Management  Partners IV, L.L.C., a Delaware limited  liability
                  company  ("DMP IV") and the  general  partner of DV IV and DBI
                  IV,  James J.  Bochnowski  ("Bochnowski"),  David L.  Douglass
                  ("Douglass") and Donald J. Lothrop  ("Lothrop"),  the managing
                  members of DMP IV. The foregoing  entities and individuals are
                  collectively referred to as the "Reporting Persons".

                  DMP IV is the  general  partner of DV IV and DBI IV and may be
                  deemed to have sole power to vote and sole power to dispose of
                  shares  of the  issuer  directly  owned  by DV IV and  DBI IV.
                  Bochnowski,  Douglass and Lothrop are the managing  members of
                  DMP IV and may be  deemed  to have  shared  power  to vote and
                  shared  power to dispose of the shares of the issuer  directly
                  owned by DV IV and DBI IV.

ITEM 2(B).        ADDRESS OF PRINCIPAL BUSINESS OFFICE, OR, IF NONE, RESIDENCE:
                  -------------------------------------------------------------

                  The address of the principal  business  office for each of the
                  Reporting Persons is:

                  Delphi Ventures
                  3000 Sand Hill Road
                  Building 1 - Suite 135
                  Menlo Park, CA  94025

ITEM 2(C)         CITIZENSHIP:
                  ------------

                  DV IV and DBI IV are Delaware limited partnerships.  DMP IV is
                  a Delaware limited liability company. Bochnowski, Douglass and
                  Lothrop are United States citizens.

ITEM 2(D) AND ITEM 2(E).   TITLE OF CLASS OF SECURITIES AND CUSIP NUMBER:
                           ----------------------------------------------

                  Common Stock
                  CUSIP # 641255104

ITEM 3.           Not Applicable.

                                                              Page 9 of 14 Pages

ITEM 4.           OWNERSHIP:
                  ----------

                  The following information with respect to the ownership of the
                  Common  Stock  of  the  issuer  by  the  persons  filing  this
                  Statement is provided as of December 31, 2004:

                       (a) Amount beneficially owned:
                           --------------------------

                       See Row 9 of cover page for each Reporting Person.

                       (b) Percent of Class:
                           -----------------

                       See Row 11 of cover page for each Reporting Person.

                       (c) Number of shares as to which such person has:
                           ---------------------------------------------

                                 (i) Sole power to vote or to direct the vote:
                                     -----------------------------------------

                                 See Row 5 of  cover  page  for  each  Reporting
                                 Person.

                                 (ii)  Shared  power  to vote or to  direct  the
                                       -----------------------------------------
                                 vote:
                                 -----

                                 See Row 6 of  cover  page  for  each  Reporting
                                 Person.

                                 (iii)  Sole  power to  dispose or to direct the
                                        ----------------------------------------
                                 disposition of:
                                 ---------------

                                 See Row 7 of  cover  page  for  each  Reporting
                                 Person.

                                 (iv)  Shared  power to dispose or to direct the
                                       -----------------------------------------
                                 disposition of:
                                 ---------------

                                 See Row 8 of  cover  page  for  each  Reporting
                                 Person.

ITEM 5.        OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS:
               ---------------------------------------------

               Not applicable.

ITEM 6.        OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON:
               ---------------------------------------------------------------

               Under certain  circumstances set forth in the limited partnership
               agreements of DV IV and DBI IV, and the limited liability company
               agreement of DMP IV, the general and limited partners or members,
               as the case may be,  of each of such  entities  may be  deemed to
               have the right to receive  dividends  from, or the proceeds from,
               the sale of shares  of the  issuer  owned by each such  entity of
               which they are a partner.

ITEM 7.        IDENTIFICATION   AND   CLASSIFICATION  OF  THE  SUBSIDIARY  WHICH
               ACQUIRED THE  SECURITY  BEING  REPORTED ON BY THE PARENT  HOLDING
               COMPANY:
               -----------------------------------------------------------------

               Not applicable.


                                                             Page 10 of 14 Pages


ITEM 8.        IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP:
               ---------------------------------------------------------

               Not applicable.

ITEM 9.        NOTICE OF DISSOLUTION OF GROUP:
               ------------------------------

               Not applicable.

ITEM 10.       CERTIFICATION:
               -------------

               Not applicable.






                                                             Page 11 of 14 Pages


                                   SIGNATURES


         After reasonable  inquiry and to the best of my knowledge and belief, I
certify that the information  set forth in this statement is true,  complete and
correct.


Dated:  February 11, 2005


                                    DELPHI VENTURES IV, L.P., a Delaware 
                                    Limited Partnership


                                    By:  Delphi Management Partners IV, L.L.C.,
                                         a Delaware Limited Liability Company
                                         Its General Partner



                                    By:    /s/ James J. Bochnowski              
                                           -------------------------------------
                                           James J. Bochnowski, 
                                           Member


                                    DELPHI BIOINVESTMENTS IV, L.P., a Delaware 
                                    Limited Partnership

                                    By:  Delphi Management Partners IV, L.L.C.,
                                         a Delaware Limited Liability Company
                                         Its General Partner



                                    By:    /s/ James J. Bochnowski              
                                           -------------------------------------
                                           James J. Bochnowski, 
                                           Member


                                    DELPHI MANAGEMENT PARTNERS IV, L.L.C., 
                                    a Delaware Limited Liability Company


                                    By:    /s/ James J. Bochnowski              
                                           -------------------------------------
                                           James J. Bochnowski, 
                                           Member



                                                             Page 12 of 14 Pages



                                    JAMES J. BOCHNOWSKI


                                    By:    /s/ James J. Bochnowski        
                                           -------------------------------
                                           James J. Bochnowski


                                    DAVID L. DOUGLASS


                                    By:    /s/ David L. Douglass          
                                           -------------------------------
                                           David L. Douglass


                                    DONALD J. LOTHROP



                                    By:    /s/ Donald J. Lothrop  
                                           -----------------------
                                           Donald J. Lothrop



                                                             Page 13 of 14 Pages


                                  EXHIBIT INDEX


                                                                 Found on
                                                               Sequentially
Exhibit                                                        Numbered Page
-------                                                        -------------
Exhibit A:  Agreement of Joint Filing                               14






                                                             Page 14 of 14 Pages


                                    EXHIBIT A


                            Agreement of Joint Filing

         The  undersigned  hereby  agree  that a  single  Schedule  13G  (or any
amendment  thereto) relating to the Common Stock of Neometrix  Technology Group,
Inc. shall be filed on behalf of each of the undersigned and that this Agreement
shall be filed as an exhibit to such Schedule 13G.

Date:  February 11, 2005

February 11, 2005                     DELPHI MANAGEMENT PARTNERS IV, L.L.C.,
                                      a Delaware Limited Liability Company


                                      By: /s/ James J. Bochnowski 
                                         --------------------------------
                                          James J. Bochnowski, Member


February 11, 2005                     DELPHI VENTURES IV, L.P.,
                                      a Delaware Limited Partnership

                                      By: Delphi Management Partners IV, L.L.C.,
                                          a Delaware Limited Liability Company
                                          Its General Partner


                                      By: /s/ James J. Bochnowski 
                                         --------------------------------
                                          James J. Bochnowski, Member


February 11, 2005                     DELPHI BIOINVESTMENTS IV, L.P.,
                                      a Delaware Limited Partnership

                                      By: Delphi Management Partners IV, L.L.C.,
                                          a Delaware Limited Liability Company
                                          Its General Partner


                                      By:  /s/ James J. Bochnowski 
                                         --------------------------------
                                           James J. Bochnowski, Member


February 11, 2005                     By:   /s/ James J. Bochnowski             
                                            ------------------------------------
                                            James J. Bochnowski


February 11, 2005                     By:   /s/ David L. Douglass               
                                            ------------------------------------
                                            David L. Douglass


February 11, 2005                     By:   /s/ Donald J. Lothrop               
                                            ------------------------------------
                                            Donald J. Lothrop