1
                                PRELIMINARY COPY

                                  SCHEDULE 14A
                                 (Rule 14a-101)
                     INFORMATION REQUIRED IN PROXY STATEMENT

                            SCHEDULE 14A INFORMATION

                Proxy Statement Pursuant to Section 14 (a) of the
               Securities Exchange Act of 1934 (Amendment No.___)


Filed by the Registrant [X]

Filed by a Party other than the Registrant [   ]

Check the appropriate box:


                                                    

[X]  Preliminary Proxy Statement                       [   ]  Confidential, For Use of the Commission Only
                                                               (as permitted by Rule 14a-6(e)(2))


[   ]  Definitive Proxy Statement

[   ]  Definitive Additional Materials

[   ]  Soliciting Material Under Rule 14a-12

                                  ALTEON INC.

                 Name of Registrant as Specified in Its Charter


    (Name of Person(s) Filing Proxy Statement, if other than the Registrant)

Payment of Filing Fee (Check the appropriate box):


[X]  No fee required.

[ ] Fee computed on table below per Exchange Act Rules 14a-6(i)(1) and 0-11.

       (1) Title of each class of securities to which transaction applies:


       (2) Aggregate number of securities to which transaction applies:


       (3)Per unit price or other underlying value of transaction computed
          pursuant to Exchange Act Rule 0-11 (set forth the amount on which the
          filing fee is calculated and state how it was determined):


       (4) Proposed maximum aggregate value of transaction:


       (5) Total fee paid:
   2
[ ] Fee paid previously with preliminary materials.

[ ]  Check box if any part of the fee is offset as provided by Exchange
     Act Rule 0-11(a)(2) and identify the filing for which the offsetting
     fee was paid previously. Identify the previous filing by registration
     statement number, or the form or schedule and the date of its filing.

   (1)      Amount previously paid:



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   (4)      Date Filed:
   3
                                   ALTEON INC.
                               170 WILLIAMS DRIVE
                            RAMSEY, NEW JERSEY 07446


To Our Stockholders:

         You are most cordially invited to attend the 2001 Annual Meeting of
Stockholders of Alteon Inc. at 9:00 A.M., local time, on June 5, 2001, at the
American Stock Exchange, 86 Trinity Place, New York, New York 10006.

       The Notice of Meeting and Proxy Statement on the following pages describe
the matters to be presented at the meeting.

       It is important that your shares be represented at this meeting to assure
the presence of a quorum. Whether or not you plan to attend the meeting, we hope
that you will have your stock represented by signing, dating and returning your
proxy in the enclosed envelope, which requires no postage if mailed in the
United States, as soon as possible. Your stock will be voted in accordance with
the instructions you have given in your proxy.

       Thank you for your continued support.

                                   Sincerely,

                                   /s/ Kenneth I. Moch
                                   -------------------------------------
                                   KENNETH I. MOCH
                                   President and Chief Executive Officer
   4
                                   ALTEON INC.
                               170 WILLIAMS DRIVE
                            RAMSEY, NEW JERSEY 07446

                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
                             TO BE HELD JUNE 5, 2001

         The Annual Meeting of Stockholders of Alteon Inc., a Delaware
corporation will be held at the American Stock Exchange, 86 Trinity Place, New
York, New York 10006, on June 5, 2001, at 9:00 A.M., local time, for the
following purposes:

         (1)      To elect two directors to serve until the Annual Meeting to be
                  held in 2004 and until their successors shall have been duly
                  elected and qualified;

         (2)      To approve an amendment to our Restated Certificate of
                  Incorporation increasing the number of authorized shares from
                  forty million to eighty million;

         (3)      To ratify an amendment to our Amended 1995 Stock Option Plan
                  increasing the number of available shares from four million to
                  seven million;

         (4)      To ratify the appointment of Arthur Andersen LLP to serve as
                  our independent public accountants for the fiscal year ending
                  December 31, 2001; and

         (5)      To transact such other business as may properly come before
                  the meeting or any adjournment or adjournments thereof.

       Only stockholders of record at the close of business on April 9, 2001,
are entitled to vote at the meeting, or at any adjournment of the meeting. A
complete list of those stockholders will be open to the examination of any
stockholder at our principal executive offices at 170 Williams Drive, Ramsey,
New Jersey 07446 and at the American Stock Exchange, 86 Trinity Place, New York,
New York 10006, for a period of 10 days prior to the meeting. The meeting may be
adjourned from time to time without notice other than by announcement at the
meeting.

       IT IS IMPORTANT THAT YOUR SHARES BE REPRESENTED REGARDLESS OF THE NUMBER
OF SHARES YOU MAY HOLD. WHETHER OR NOT YOU PLAN TO ATTEND THE MEETING IN PERSON,
PLEASE COMPLETE, DATE AND SIGN THE ENCLOSED PROXY CARD AND MAIL IT PROMPTLY IN
THE ENCLOSED RETURN ENVELOPE. THE PROMPT RETURN OF PROXIES WILL INSURE A QUORUM
AND SAVE ALTEON THE EXPENSE OF FURTHER SOLICITATION. EACH PROXY GRANTED MAY BE
REVOKED BY THE STOCKHOLDER APPOINTING SUCH PROXY AT ANY TIME BEFORE IT IS VOTED.
IF YOU RECEIVE MORE THAN ONE PROXY CARD BECAUSE YOUR SHARES ARE REGISTERED IN
DIFFERENT NAMES OR ADDRESSES, EACH SUCH PROXY CARD SHOULD BE SIGNED AND RETURNED
TO ASSURE THAT ALL OF YOUR SHARES WILL BE VOTED.

                                      By Order of the Board of Directors
                                      /s/ Elizabeth A. O'Dell
                                      ---------------------------------------
                                      ELIZABETH A. O'DELL
                                      Secretary
Ramsey, New Jersey
____________, 2001



        THE COMPANY'S 2000 ANNUAL REPORT ACCOMPANIES THE PROXY STATEMENT.
   5
                                   ALTEON INC.
                               170 WILLIAMS DRIVE
                            RAMSEY, NEW JERSEY 07446

                                 PROXY STATEMENT

       We are furnishing this Proxy Statement in connection with our Annual
Meeting of Stockholders to be held on June 5, 2001, at the American Stock
Exchange, 86 Trinity Place, New York, New York 10006, at 9:00 A.M., local time,
and at any adjournment or adjournments thereof. Stockholders of record at the
close of business on April 9, 2001, will be entitled to vote at the meeting and
at any adjournment of the meeting. As of April 9, 2001, there were __________
shares of common stock issued and outstanding and entitled to vote. Each share
of common stock is entitled to one vote on any matter presented at the meeting.

       You may vote in person at the meeting or by proxy. We recommend you vote
by proxy even if you plan to attend the meeting. You can always change your vote
at the meeting.

       Alteon's Board of Directors is asking for your proxy. Giving us your
proxy by properly signing and returning the accompanying proxy card means, you
authorize us to vote your shares at the meeting in the manner you direct. You
may vote for both, one or neither of our director candidates. You may also vote
for or against the other proposals, or abstain from voting. We will vote as you
direct.

       If you properly sign and return the enclosed proxy card but do not
specify how to vote, we will vote your shares (i) FOR the election of the
nominees named below as directors; (ii) FOR the approval of the amendment to the
Restated Certificate of Incorporation increasing the number of authorized
shares; (iii) FOR the ratification of the amendment to the Amended 1995 Stock
Option Plan increasing the number of available shares; (iv) FOR the ratification
of the appointment of Arthur Andersen LLP as independent public accountants for
the year ending December 31, 2001; and (v) in the discretion of the persons
named in the enclosed form of proxy, on any other proposals which may properly
come before the meeting or any adjournment of the meeting.

       You may receive more than one proxy or voting card depending on how you
hold your shares. Shares registered in your name are covered by one card.
However, if you hold shares through someone else, such as a stockbroker, you may
receive material from them asking how you want to vote. Each proxy card should
be signed and returned to assure that all of your shares are voted.

       You may revoke your proxy any time before it is voted by submitting a new
proxy with a later date, by voting in person at the meeting or by notifying
Alteon's Secretary in writing. However, your mere presence at the meeting does
not revoke the proxy.

       In order to carry on the business of the meeting, we must have a quorum.
This means the holders of at least a majority of our common stock must be
represented at the meeting, either by proxy or in person. Votes that are
withheld, abstentions and broker non-votes will be counted for purposes of
determining the presence or absence of a quorum.

       The two nominees receiving the most votes will be elected to fill the
seats on the Board. In accordance with the Delaware Corporation Act, the
proposed amendment to the Restated Certificate of Incorporation to increase the
number of shares authorized for issuance must be approved by the affirmative
vote of the holders of at least a majority of the outstanding shares of our
common stock entitled to vote thereon. If you abstain from voting on this
proposal, or do not give instructions to your broker on how to vote, it has the
same effect as if you voted against that proposal. All other actions proposed in
this Proxy Statement and/or considered at the meeting, including an adjournment,
may be taken upon the favorable vote of a majority of the votes cast.

       Except as noted above, only votes for or against these proposals count.
Brokers may submit proxies that do not indicate a vote for a proposal because
such brokers do not have discretionary voting authority on the proposal and have
not received instructions from their customers on those proposals (i.e., broker
non-votes). These broker non-votes are

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not considered to be shares present for the purpose of calculating the vote on a
proposal and, except as described above, will not affect the outcome of such a
proposal. Similarly, abstentions to a proposal are not counted as votes cast in
favor of the proposal and, accordingly, except in the case of the proposal
regarding the amendment to the Restated Certificate of Incorporation, will have
no effect on the outcome of a vote on such a proposal.

       This Proxy Statement, together with the related proxy card, is being
mailed to you on or about April 19, 2001. Our Annual Report to Stockholders for
the year ended December 31, 2000, including financial statements, is being
mailed concurrently with this Proxy Statement to all stockholders of record as
of April 9, 2001. In addition, we have provided brokers, dealers, banks, voting
trustees and their nominees, at our expense, with additional copies of the
annual report so that they may supply the material to beneficial owners as of
April 9, 2001.

                              ELECTION OF DIRECTORS

       At the meeting, two directors are to be elected to hold office until the
Annual Meeting of Stockholders to be held in 2004 and until their successors are
elected and qualified. The nominees for election to the Board of Directors are
Marilyn G. Breslow and Alan J. Dalby. Their biographies appear below.

         Pursuant to our Restated Certificate of Incorporation, the Board of
Directors is divided into three classes, each of which serves a term of three
years. Class A consists of Ms. Breslow and Mr. Dalby, whose terms will expire at
the meeting. Class B consists of Mr. Moch, Dr. Bransome and Dr. Naimark, whose
terms will expire at the Annual Meeting of Stockholders in 2002. Class C
consists of Dr. Novitch and Mr. McCurdy, whose terms will expire at the Annual
Meeting of the Stockholders in 2003.

       Proxies solicited by the Board will be voted for the election of the
nominees named above, unless otherwise specified in the proxy. All of the
persons whose names and biographies appear below are at present directors of
Alteon. In the event a nominee should become unavailable or unable to serve as a
director, it is intended that votes will be cast for a substitute nominee
designated by the Board of Directors. The Board of Directors has no reason to
believe that the nominees named will be unable to serve if elected. The nominees
have consented to being named in this Proxy Statement and to serve if elected.

       The current Board of Directors, including the nominees, is comprised of
the following persons:



                                                        SERVED AS A
                  NAME                       AGE       DIRECTOR SINCE               POSITIONS WITH ALTEON
      ---------------------------------      ---       --------------               ---------------------
                                                                           
      Mark Novitch, M.D................       69            1994                    Chairman of the Board

      Kenneth I. Moch..................       46            1998                    President, Chief Executive Officer
                                                                                    and Director

      Edwin D. Bransome, Jr., M.D......       67            1999                    Director

      Marilyn G. Breslow (1)...........       57            1988                    Director

      Alan J. Dalby (1)................       64            1994                    Director

      David McCurdy....................       51            1997                    Director

      George M. Naimark, Ph.D..........       76            1999                    Director

-------------
(1)  A nominee for election to the Board of Directors.

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         The principal occupations and business experience, for at least the
past five years, of each director are as follows:

         Mark Novitch, M.D., was elected as a director of Alteon in June 1994.
He retired as Vice Chairman and Chief Compliance Officer of the Upjohn Company
in December 1993. Prior to joining Upjohn in 1985, he was Deputy Commissioner of
the U.S. Food and Drug Administration. Dr. Novitch is a director of Guidant
Corporation, a supplier of cardiology and minimally invasive surgery products;
Neurogen Corporation, a biopharmaceutical firm focused on central nervous system
disorders; Calypte Biomedical, a developer of urine-based diagnostics; and Kos
Pharmaceuticals, Inc., a developer of pharmaceutical products for cardiovascular
and respiratory conditions. Dr. Novitch is an Adjunct Professor of Health Care
Sciences at The George Washington University.

         Kenneth I. Moch, who was elected President, Chief Executive Officer and
a director of Alteon in December 1998, joined us in February 1995, as Senior
Vice President, Finance and Business Development and Chief Financial Officer.
Mr. Moch has acquired substantial experience in managing advanced biomedical
technologies as both an operating executive and a strategist. From 1990 to 1995,
he served as President and Chief Executive Officer of Biocyte Corporation, a
cellular therapy company that pioneered the use of cord blood stem cells in
transplantation therapy. Mr. Moch was a founder and the Managing General Partner
of Catalyst Ventures, a seed venture capital partnership, and was a founder of
The Liposome Company, Inc. in Princeton, New Jersey, where he served as Vice
President from 1982 to 1988. Previously, he was a management consultant with
McKinsey & Company, Inc., a biomedical technology consultant with Channing,
Weinberg & Company, Inc. (now The Wilkerson Group) and held product management
responsibilities in the Parenteral Products Division of Baxter International.
Mr. Moch received his A.B. in biochemistry from Princeton University, and an
M.B.A. with emphasis in finance and marketing from the Stanford Graduate School
of Business.

         Edwin D. Bransome, Jr., M.D., has been a director of Alteon since June
1999. Dr. Bransome is a Professor of Medicine and Physiology Emeritus at the
Medical College of Georgia from which he retired as Chief of the Section of
Endocrinology and Metabolism in 2000. Dr. Bransome is the Past President of the
United States Pharmacopoeial Convention and has been a member of the USP Board
of Trustees since 1990. He served on the Georgia Department of Medical
Assistance (Medicaid) Drug Utilization Board from 1992-2000 and was its first
Chairman. Currently, Dr. Bransome is in medical practice as a consultant in
Endocrinology and is Medical Director of the Diabetes Treatment Center at the
Aiken, South Carolina Regional Medical Center. He has had faculty positions at
the Scripps Clinic and Research Foundation, MIT and the Harvard University
School of Medicine. He received his A.B. in 1954 from Yale University and
received his M.D. from Columbia University College of Physicians and Surgeons in
1958. His post-graduate training in Internal Medicine and Clinical Endocrinology
fellowship was at the Peter Bent Brigham Hospital in Boston and in Biochemistry
at Columbia University College of Physicians and Surgeons.

         Marilyn G. Breslow has been a director of Alteon since June 1988. She
has been a Portfolio Manager/Analyst for W.P. Stewart & Co., Inc., an investment
advisory firm in New York City, since 1990, and is President and a director of
that firm. She was a General Partner of Concord Partners and a Vice President of
Dillon, Read & Co. Inc. from 1984 to 1990. Prior to Dillon, Read & Co., she
worked at Polaroid Corporation from 1973 to 1984 and was with Peat, Marwick,
Mitchell & Company from 1970 to 1972. Ms. Breslow holds a B.S. degree from
Barnard College and an M.B.A. from the Harvard Graduate School of Business
Administration.

         Alan J. Dalby was elected as a director of Alteon in December 1994. Mr.
Dalby is Chairman of Reckitt Benckiser plc, a household products company. He is
the former Chairman and Chief Executive Officer and a founder of Cambridge
NeuroScience, Inc. He was Executive Vice President and member of the Board of
Directors for SmithKline Beckman Corporation, retiring in 1987. Mr. Dalby is a
director of Acambis plc.

         Dave McCurdy, who became a director of Alteon in June 1997, is
currently the President of EIA (Electronic Industries Alliance), the premier
trade organization representing more than 2,100 of the world's leading
electronics manufacturers. Before becoming President of EIA in November 1998,
Mr. McCurdy was Chairman and Chief Executive Officer of the McCurdy Group
L.L.C., a business consulting and investment firm focused on high-growth
companies in the fields of healthcare, high technology and international
business, which he formed in 1995. Prior to forming the McCurdy Group, Mr.
McCurdy served for 14 years in the U.S. House of Representatives from the fourth

                                       7
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district of Oklahoma. He held a commission in the United States Air Force
Reserve attaining the rank of major and serving as a Judge Advocate General
(JAG). A 1972 graduate of the University of Oklahoma, Mr. McCurdy received his
J.D. in 1975 from Oklahoma's Law School. He also studied international economics
at the University of Edinburgh, Scotland, as a Rotary International Graduate
Fellow.

         George M. Naimark, Ph.D., was elected as a director of Alteon in June
1999. He is President of Naimark & Barba, Inc., a management consultancy, since
September 1966, and Naimark & Associates, Inc. a private healthcare consulting
organization, since February 1994. Dr. Naimark has more than 30 years of
experience in the pharmaceutical, diagnostic and medical device industries. His
experience includes management positions in research and development, new
product development and quality control. In addition, Dr. Naimark has authored
books on patent law and communications, as well as many articles that appeared
in general business, marketing, scientific and medical journals and was the
editor of a medical journal. He received his Ph.D. from the University of
Delaware in 1951, and received a B.S. and M.S. from Bucknell University in 1947
and 1948, respectively.

         THE BOARD OF DIRECTORS RECOMMENDS THAT STOCKHOLDERS VOTE FOR THE
         NOMINEES FOR THE BOARD OF DIRECTORS.


COMMITTEES AND MEETINGS OF THE BOARD

       The Board of Directors has a Compensation Committee, which reviews
salaries and incentive compensation for employees of and consultants to Alteon,
and an Audit Committee, which reviews the results and scope of the audit and
other services provided by our independent auditors. In 2000, the Audit and
Compensation Committees were comprised of Marilyn G. Breslow, Alan J. Dalby,
Edwin D. Bransome, Jr., M.D., David McCurdy, George M. Naimark, Ph.D., and Mark
Novitch, M.D. All of the members of the Audit Committee are independent, as such
term is defined by Section 121 of the American Stock Exchange listing standards.
The Audit Committee and Compensation Committee each held two meetings during the
year ended December 31, 2000. There were nine meetings of the Board of Directors
in 2000. With the exception of Mr. McCurdy, each director and each committee
member attended at least 75% of all meetings of the Board of Directors and the
committee(s) on which he or she served during the period in which he or she
served as a director or committee member. We have adopted a written charter for
the Audit Committee, which is attached to this Proxy Statement as Appendix 1.

COMPENSATION OF DIRECTORS

       All of the directors are reimbursed for their expenses for each Board and
committee meeting attended. Directors who are not compensated as Alteon
employees receive $1,500 per meeting for their service to the Board.
Non-compensated directors also receive, upon the date of their election or
re-election to the Board and on the dates of the two Annual Meetings of
Stockholders following their election or re-election to the Board (subject to
their continued service on the Board of Directors), a stock option to purchase
20,000 shares of common stock (subject to adjustment if they received stock
options upon appointment to the Board between Annual Meetings of Stockholders to
fill a vacancy or newly created directorship) at an exercise price equal to the
fair market value of the common stock on the date of grant. Each of these
options will vest and become exercisable on the date of Alteon's first Annual
Meeting of Stockholders following the date of grant, subject to the director's
continued service on the Board.

       On December 15, 1998, Dr. Novitch entered into a two-year agreement with
Alteon regarding his service as Chairman of the Board, pursuant to which Dr.
Novitch received $60,000 a year, payable in monthly installments, and an option
to purchase 200,000 shares of common stock at an exercise price of $0.875 per
share. Effective December 2000, this agreement was amended to, among other
things, extend the term to June 30, 2001. Under the amended agreement, Dr.
Novitch continues to receive $60,000 per year, payable in monthly installments,
and was granted an option to purchase an additional 50,000 shares at an exercise
price of $7.00 per share.

                                       8
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                               EXECUTIVE OFFICERS

       The following table identifies our current executive officers:



                     NAME                   AGE          CAPACITIES IN WHICH SERVED      IN CURRENT POSITIONS SINCE
                     ----                   ---          --------------------------      --------------------------

                                                                                
      Kenneth I. Moch..................     46           President, Chief Executive            December 1998
                                                            Officer and Director

      Robert C. deGroof, Ph.D. (1)....      56           Senior Vice President                 March 2000
                                                            Scientific Affairs

      Elizabeth A. O'Dell (2)............   40           Vice President, Finance and           October 1993
                                                            Administration, Secretary
                                                            and Treasurer


------

(1)      Robert C. deGroof, Ph.D., was appointed Senior Vice President,
         Scientific Affairs in March 2000. From April 1990 to February 2000, he
         was the President of Keystone Scientific Management, which provided
         strategic clinical and non-clinical development advice to many
         pharmaceutical companies. Prior to that, he was the Director of
         Regulatory Affairs of World Wide Development Operations at
         Bristol-Myers Squibb from July 1987 to March 1990. From October 1984 to
         July 1987, he was the Assistant Director of Regulatory Affairs at
         McNeil Consumer Products. Prior to that, he was Assistant Professor of
         Pharmacology at Jefferson Medical College, Thomas Jefferson University.
         Dr. deGroof received his B.S. at the University of Florida in 1967 and
         his Ph.D. in Physiology and Pharmacology from Duke University in 1973.

(2)      Elizabeth A. O'Dell has been Vice President, Finance and
         Administration, Secretary and Treasurer since October 1993. She served
         as the Company's Director of Finance from February 1993 to September
         1993 and as Controller of the Company from February 1992 to February
         1993. From November 1991 to January 1992, she was the Controller of
         Radiodetection Corp. She was the Director of Internal Operations of
         Kratos Analytical, Inc. from May 1990 to November 1991 and Controller
         from March 1987 to April 1990. Prior to that, she served for five years
         in public accounting in various positions at Coopers & Lybrand (now
         PricewaterhouseCoopers LLP) and Deloitte & Touche. Ms. O'Dell received
         her B.B.A. and M.B.A. from Pace University. She is also a CPA in New
         Jersey.

                                       9
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                             EXECUTIVE COMPENSATION

         The following table sets forth certain information concerning the
annual and long-term compensation for the fiscal years ended December 31, 2000,
1999 and 1998 of our Chief Executive Officer and two other highly compensated
executive officers of Alteon who were serving as executive officers at December
31, 2000, or who served as executive officers during the fiscal year ended
December 31, 2000 (collectively, the "Named Officers"):

                           SUMMARY COMPENSATION TABLE



                                                                                     LONG-TERM
                                                                                    COMPENSATION
                                                                                       STOCK
                                           ANNUAL COMPENSATION                       OPTION AWARDS       ALL OTHER
NAME AND PRINCIPAL POSITION             YEAR      SALARY         BONUS              (NUMBER OF SHARES)  COMPENSATION
---------------------------             ----      ------         -----              ------------------  ------------

                                                                                         
Kenneth I. Moch...............        2000      $ 310,500     $100,000 (1)           325,000            $  ----
   President and                      1999        300,000         ----             1,205,000 (2)           ----
   Chief Executive Officer            1998        198,199       12,500               200,000               ----


Robert C. deGroof (3).........        2000      $ 166,666     $   ----               325,000            $22,500 (4)
   Senior Vice President
   Scientific Affairs


Elizabeth A. O'Dell...........        2000      $ 145,000     $   ----               127,500            $  ----
   Vice President, Finance and        1999        140,000         ----               240,000 (5)           ----
   Administration, Secretary          1998        119,758       20,000 (6)            ----                 ----
   and Treasurer

----------------------

(1)      Represents a deferred performance bonus for the year ending December
         31, 2000.

(2)      Includes options for 405,000 shares repriced on February 2, 1999.

(3)      Dr. deGroof began serving as Senior Vice President, Scientific Affairs
         in March 2000.

(4)      Represents a housing allowance.

(5)      Includes options for 165,000 shares repriced on February 2, 1999.

(6)      Includes a deferred performance bonus of $15,000 for the year ending
         December 31, 1998.

                                       10
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         The following table sets forth certain information concerning grants of
stock options during the fiscal year ended December 31, 2000, to the Named
Officers:

                        OPTION GRANTS IN LAST FISCAL YEAR



                                               PERCENTAGE                                POTENTIAL REALIZABLE
                                                OF TOTAL                                   VALUE AT ASSUMED
                                 NUMBER OF      OPTIONS                                     ANNUAL RATES OF
                                SECURITIES     GRANTED TO                                     STOCK PRICE
                                UNDERLYING     EMPLOYEES    EXERCISE OR                    APPRECIATION FOR
                                  OPTIONS          IN        BASE PRICE   EXPIRATION          OPTION TERM (1)
           NAME                   GRANTED     FISCAL 2000     PER SHARE     DATE            5%           10%
           ----                   -------     -----------     ---------     ----            --           ---

                                                                                    
Kenneth I. Moch...........        200,000          21.0%    $   3.563     03/14/10     $  448,087     $1,135,542
                                  125,000          13.1%        7.000     11/08/10        550,283      1,394,525


Robert C. deGroof.........        250,000          26.2%    $   3.563     03/14/10     $  560,109     $1,419,427
                                   75,000           7.9%        7.000     11/08/10        330,170        836,715

Elizabeth A. O'Dell.......         25,000           2.6%    $   3.563     03/14/10     $   56,011     $  141,943
                                   72,500           7.6%        2.875     09/06/10        131,085        332,196
                                   30,000           3.1%        7.000     11/08/10        132,068        334,686



----------

(1)  The dollar amounts under these columns are the result of calculations
     assuming that the price of common stock on the date of the grant of the
     option increases at the hypothetical 5% and 10% rates set by the Securities
     and Exchange Commission and therefore are not intended to forecast possible
     future appreciation, if any, of our stock price over the option term of 10
     years.


                 AGGREGATED OPTION EXERCISES IN LAST FISCAL YEAR
                        AND FISCAL YEAR-END OPTION VALUES



                                                                 NUMBER OF
                                    SHARES                   SECURITIES UNDERLYING        VALUE OF UNEXERCISED
                                   ACQUIRED                  UNEXERCISED OPTIONS          IN-THE-MONEY OPTIONS
                                     ON                      AT DECEMBER 31, 2000         AT DECEMBER 31, 2000 (1)
                                   EXERCISE     VALUE        --------------------         ------------------------
              NAME                   (#)      REALIZED  EXERCISABLE   UNEXERCISABLE  EXERCISABLE    UNEXERCISABLE
              ----                   ---      --------  -----------   -------------  -----------    -------------
                                                                                   
  Kenneth I. Moch............      5,000      $6,563        810,000       715,000     $1,799,598      $1,149,263

  Robert C. deGroof..........       ----      $  ----        10,000       315,000     $    ----       $   ----

  Elizabeth A. O'Dell........       ----      $  ----       169,375       198,125     $  370,740      $  235,271


---------------

(1)  Based on the closing price on the American Stock Exchange at December
     31, 2000 ($3.4375).

                                       11
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COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION

         The persons who served as members of the Compensation Committee of the
Board of Directors during 2000 were Alan J. Dalby, Edwin D. Bransome, Jr., M.D.,
Marilyn G. Breslow, David McCurdy, George M. Naimark, Ph.D. and Mark Novitch,
M.D. None of the members of the Compensation Committee was an officer, former
officer or employee of Alteon.

COMPENSATION COMMITTEE REPORT ON EXECUTIVE COMPENSATION

General Policies

         The Compensation Committee (the "Committee") of the Board of Directors
is responsible for establishing and monitoring the general compensation policies
and compensation plans of Alteon, as well as the specific compensation levels
for executive officers. It also makes recommendations to the Board of Directors
concerning the granting of options under our Amended and Restated 1987 Stock
Option Plan and Amended 1995 Stock Option Plan.

         Under the supervision of the Committee, Alteon has developed and
implemented compensation policies, plans and programs which (1) provide a total
compensation package which is intended to be competitive within the industry so
as to enable us to attract and retain high-caliber executive personnel, and (2)
seek to align the financial interests of our employees with those of its
stockholders by relying heavily on long-term incentive compensation which is
tied to performance.

       The primary components of executive compensation include base salary and
long-term equity incentives in the form of stock options. As we have not yet
generated any revenue from the sale of pharmaceutical products, we rely on
long-term incentive compensation (i.e., stock options) to motivate the executive
officers and other employees. This allows us to retain cash for research and
development projects. In determining the size of stock option grants to
individual executives, the Committee considers a number of factors, including
the following: the level of an executive's job responsibilities; the executive's
past performance; the size and frequency of grants by comparable companies; the
executive's salary level; the need to provide incentive for the purpose of
retaining qualified personnel in light of our current conditions and prospects;
the size of any prior grants; and the achievement of designated milestones by
the executive. The Committee assigns no specific weight to any of the foregoing
(other than achievement of designated milestones by the executive in cases where
the executive's employment agreement provides for a grant of a specific size
upon achievement of the milestone) when making determinations as to the size of
stock option grants.

       Executive officers are also eligible to earn an annual cash incentive
award, the amount of which is based upon (1) the position level of the executive
officer, and (2) the attainment of specific individual non-financial performance
objectives. The Committee sets the performance objectives at the beginning of
the fiscal year.

       The Chief Executive Officer is responsible for the development of the
annual salary plan for executive officers other than himself. The plan is based
on industry and peer group comparisons and national surveys and on performance
judgments as to the past and expected future contributions of the individuals.
To maintain a competitive level of compensation, Alteon targets base salary at
the upper percentiles of a comparative group composed of other biotechnology
companies. Base salary may exceed this level as a result of individual
performance. The Committee reviews the annual plan and makes recommendations to
the Board of Directors, with any modifications it deems appropriate. The
Committee believes it has established executive compensation levels which are
competitive with companies in the industry, taking into account individual
experience, performance of both Alteon and the individual, company size,
location and stage of development.

Compensation of the Chief Executive Officer

       Mr. Moch's compensation was determined on the basis of his expertise and
experience, which include approximately 20 years of experience in the
biotechnology and venture capital fields. Mr. Moch received a base salary of
$310,500 in 2000. The Committee believes that Mr. Moch's compensation
arrangements reflect the compensation package necessary to retain his services
for Alteon in light of our current condition and prospects and is commensurate

                                       12
   13
with his expertise and experience as well as with compensation offered by
comparable biotechnology companies.

       Effective January 1, 1994, the Internal Revenue Code does not permit
corporations to deduct payment of certain compensation in excess of $1,000,000
to the chief executive officer and the four other most highly paid executive
officers. All compensation paid to our executive officers for 2000 will be fully
deductible and the Committee anticipates that amounts paid as cash compensation
will continue to be fully deductible because the amounts are expected to be less
than the $1,000,000 threshold. Under certain circumstances, the executive
officers may realize compensation upon the exercise of stock options granted
under our stock option plans which would not be deductible by Alteon. We expect
to take such action as is necessary to qualify our stock option plans as
"performance-based compensation," which is not subject to the limitation, if and
when the Committee determines that the effect of the limitation on deductibility
warrants such action.

                                                   COMPENSATION COMMITTEE
                                                   Alan J. Dalby
                                                   Edwin D. Bransome, Jr., M.D.
                                                   Marilyn G. Breslow
                                                   David McCurdy
                                                   George M. Naimark, Ph.D.
                                                   Mark Novitch, M.D.


                             AUDIT COMMITTEE REPORT

       The Audit Committee, which is responsible for reviewing the results and
scope of the audit and other services provided by our independent auditors, has
reviewed our audited annual financial statements and the related report by
Arthur Andersen LLP, our independent public accountants, and has discussed the
audited financial statements and report with management and with the independent
public accountants.

       The Audit Committee has also discussed with management and the
independent public accountants the matters required to be discussed by the
Codification of Statement of Auditing Standards, AU Section 380, also known as
SAS 61, as currently in effect. These matters include: significant accounting
policies, management judgments and accounting estimates, management's
consultation with other accountants, and any difficulties encountered in
performing the audit, significant audit adjustment, or disagreements with
management.

       As required by Independence Standards Board Standard No. 1, as currently
in effect, Arthur Andersen LLP has disclosed to the Audit Committee any
relationships between it (and its related entities) and Alteon (and its related
entities), which, in its professional judgment may reasonably be thought to
affect its ability to be independent. In addition, Arthur Andersen LLP has
discussed its independence with the Audit Committee and confirmed in a letter to
the Audit Committee that, in its professional judgment, it is independent of
Alteon within the meaning of the Securities Act of 1933 and the Securities
Exchange Act of 1934.

       Based on the review and discussions described above, the Audit Committee
recommended to our Board of Directors that the audited financial statements be
included in our annual report on Form 10-K for the fiscal year ended December
31, 2000 for filing with the Securities and Exchange Commission.

                                                   AUDIT COMMITTEE
                                                   Marilyn G. Breslow
                                                   Edwin D. Bransome, Jr., M.D.
                                                   Alan J. Dalby
                                                   David McCurdy
                                                   George M. Naimark, Ph.D.
                                                   Mark Novitch, M.D.

                                       13
   14
STOCKHOLDER RETURN PERFORMANCE PRESENTATION




       The following graph compares the cumulative total stockholder return on
our common stock over the five-year period ending December 31, 2000, with the
cumulative total return of the NASDAQ CRSP Total Return Index for the NASDAQ
Stock Market (U.S. Companies) (the "NASDAQ-US"), NASDAQ Pharmaceutical Stocks
Index (the "NASDAQ-Pharm"), the American Stock Exchange U.S. Index ("Amex US")
and the American Stock Exchange Health Products & Services Index ("Amex HP&S").
The graph assumes (i) an investment of $100 in our common stock and in each of
the indices, and (ii) reinvestment of all dividends. No cash dividends have been
declared on our common stock as of December 31, 2000. The stock performance set
forth below is not necessarily indicative of future price performance.

                                  [LINE GRAPH]



                     ALTEON INC. RELATIVE STOCK PERFORMANCE




                 31-Dec-95          31-Dec-96          31-Dec-97        31-Dec-98          31-Dec-99           29-Dec-00

                                                                                             
ALTEON              100.00              32.56              45.35             4.84               5.43               21.32
NASDAQ US           100.00             123.04             150.69           212.51             394.92              237.62
NASDAQ PHARM        100.00             100.31             103.66           131.95             248.01              308.49
Amex US             100.00             101.55             127.26           136.58             179.36              168.46
Amex HP&S           100.00              88.10             110.38           103.11             113.61              135.90





         The preceding performance graph and the compensation committee report
and the audit committee report contained in this Proxy Statement are not to be
incorporated by reference into filings we have made or may make under the
Securities Act of 1933, as amended, or the Securities Exchange Act of 1934, as
amended, that incorporate other filings we have made or may make under those
statutes.

EMPLOYMENT AGREEMENTS AND TERMINATION OF EMPLOYMENT ARRANGEMENTS WITH EXECUTIVE
OFFICERS

       Kenneth I. Moch entered into a three-year amended and restated employment
agreement with Alteon as of December 15, 1998. Under the amended and restated
employment agreement, Mr. Moch serves as our Chief Executive Officer and is
entitled to an annual salary of $300,000 (subject to annual review by the Board
of Directors) plus an annual bonus of up to $150,000 awarded at the discretion
of the Board of Directors. Pursuant to the agreement, on March 16, 1999, Mr.
Moch received stock options to purchase an aggregate of 600,000 shares of our
common stock.

       As of October 21, 2000, Elizabeth A. O'Dell entered into a new employment
agreement with Alteon. Under the terms of this agreement, which is due to expire
on December 31, 2003, she is entitled to an annual salary of $150,800 for the
calendar year 2001. For periods after December 31, 2001, Ms. O'Dell's salary
will be subject to annual review by the Board of Directors. Ms. O'Dell is also
eligible, at the discretion of the Board of Directors, to receive an annual cash
bonus of up to $5,000.

                                       14
   15
       Robert C. deGroof entered into a three-year employment agreement with
Alteon as of March 14, 2000. Under the employment agreement, Dr. deGroof is
entitled to an annual salary of $200,000 (subject to annual review by the Board
of Directors) plus an annual bonus of up to $25,000 awarded at the discretion of
the Board of Directors. Pursuant to the agreement, on March 14, 2000, Dr.
deGroof received stock options to purchase an aggregate of 250,000 shares of our
common stock.

       In addition to provisions in the above-described agreements requiring
each individual to maintain the confidentiality of our information and assign
inventions to us, such executive officers have agreed that during the terms of
their agreements and for one year thereafter, they will not compete with Alteon
by engaging in any capacity in any business which is competitive with our
business. The employment agreements of Mr. Moch, Dr. deGroof and Ms. O'Dell
provide that either party may terminate the agreement upon 30 days' prior
written notice, subject to a salary continuation obligation of Alteon if it
terminates the agreements without cause. Mr. Moch will receive a 12-month salary
continuation and Dr. deGroof and Ms. O'Dell will receive a six-month salary
continuation under such circumstances.

       All employment agreements between Alteon and its Vice Presidents provide
that all unvested stock options held by such Vice Presidents will vest and
become exercisable immediately in the event of a change in control of Alteon.

CHANGE IN CONTROL SEVERANCE BENEFITS PLAN

       In February 1996, we adopted the Alteon Inc. Change in Control Severance
Benefits Plan to protect and retain qualified employees and to encourage their
full attention, free from distractions caused by personal uncertainties and
risks in the event of a pending or threatened change in control of Alteon. The
Severance Plan provides for severance benefits to employees upon certain
terminations of employment after or in connection with a change in control of
Alteon as defined in the Severance Plan. Following a qualifying termination that
occurs as a result of a change in control, officers of Alteon will be entitled
to continuation of (i) their base salary for a period of 24 months, and (ii) all
benefit programs and plans providing for health and insurance benefits for a
period of up to 18 months. In addition, upon a change in control of Alteon, all
outstanding unexercisable stock options held by employees will become
exercisable.

401(k) PLAN

       We have a tax-qualified employee savings and retirement plan (the "401(k)
Plan") covering all of our employees. Pursuant to the 401(k) Plan, employees may
elect to reduce their current compensation by up to the statutorily prescribed
annual limit ($10,500 in 2001) and have the amount of such reduction contributed
to the 401(k) Plan. The 401(k) Plan does not require that we make additional
matching contributions to the Plan on behalf of participants in the Plan.
However, in 1998, we began making discretionary contributions at a rate of 25%
of employee contributions up to a maximum of 5% of their base salary.
Contributions by employees to the 401(k) Plan and income earned on such
contributions are not taxable to employees until withdrawn from the 401(k) Plan.
The Trustees under the 401(k) Plan, at the direction of each participant, invest
the assets of the 401(k) Plan.

                                       15
   16
         SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT

       The following table sets forth certain information regarding the
beneficial ownership of our common stock as of February 15, 2001, except as
otherwise set forth below, by each (i) person who is known to Alteon to own
beneficially more than 5% of the common stock, and (ii) current director and
Named Officer, including the nominees, and by all current directors and officers
as a group:



                                                                   AMOUNT AND NATURE OF          PERCENT OF
                 NAME OF BENEFICIAL OWNER (1)                    BENEFICIAL OWNERSHIP (1)        CLASS (2)
                 ----------------------------                    ------------------------        ---------

                                                                                           
S.A.C. Capital Associates, LLC.............................           2,507,322 (3)                10.87%
777 Long Ride Road
Stamford, CT 06902

Charles Livingston Grimes..................................           1,910,000 (4)                 8.50%
P.O. Box 136
Mendenhall, PA  19357

Mark Novitch, M.D..........................................             317,999 (5)                 1.40%

Kenneth I. Moch............................................           1,073,433 (6)                 4.56%

Edwin D. Bransome, Jr., M.D................................              17,500 (7)                   *

Marilyn G. Breslow**.......................................             102,071 (8)                   *

Alan J. Dalby**............................................              75,002 (9)                   *

David McCurdy..............................................              46,067 (10)                  *

George M. Naimark, Ph.D....................................              22,337 (11)                  *

Elizabeth A. O'Dell........................................             260,542 (12)                 1.15%

Robert C. deGroof, Ph.D....................................              37,084 (13)                  *

All current directors and officers as a group (9 persons)..           1,952,035 (14)                 8.00%


-------------

*        Less than one percent.
**       Nominee for election to the Board of Directors.

(1)      Beneficial ownership is determined in accordance with the rules of the
         Securities and Exchange Commission, and generally includes voting or
         investment power with respect to securities. Shares of common stock
         subject to stock options and warrants currently exercisable or
         exercisable within 60 days are deemed outstanding for computing the
         percentage ownership of the person holding such options and the
         percentage ownership of any group of which the holder is a member, but
         are not deemed outstanding for computing the percentage ownership of
         any other person. Except as indicated by footnote, and subject to
         community property laws where applicable, the persons named in the
         table have sole voting and investment power with respect to all shares
         of common stock shown as beneficially owned by them.

(2)      Applicable percentage of ownership is based on 22,492,800 shares of
         common stock outstanding.

(3)      As set forth in a Schedule 13G, dated December 31, 2000, filed by
         S.A.C. Capital Advisors, LLC, S.A.C. Capital Management, LLC and Steven
         A. Cohen. Includes 1,934,584 shares of common stock and 572,738 shares
         of common stock underlying warrants. The shares are held by S.A.C.
         Capital Associates, LLC. Pursuant to

                                       16
   17
         investment agreements, each of S.A.C. Capital Advisors and S.A.C.
         Capital Management share all investment and voting power over the
         shares. Steven A. Cohen is the Managing Member, President and Chief
         Executive Officer of S.A.C. Capital Advisors and the owner, directly
         and through a wholly owned subsidiary, of 100% of the membership
         interests of S.A.C. Capital Management. Accordingly, each of S.A.C.
         Capital Advisors, S.A.C. Capital Management and Mr. Cohen may be deemed
         to be the beneficial owner of the shares.

(4)      As set forth in a Schedule 13D, dated February 1, 2000, filed by Mr.
         Grimes with the Securities and Exchange Commission.

(5)      Includes 5,000 shares of common stock held jointly by Dr. Novitch and
         his wife and 312,999 shares of common stock subject to options that
         were exercisable as of February 15, 2001, or which will become
         exercisable within 60 days after February 15, 2001. Does not include
         options to purchase 36,668 shares of common stock which will become
         exercisable more than 60 days after February 15, 2001.

(6)      Includes 5,100 shares of common stock and 1,068,333 shares of common
         stock subject to options which were exercisable as of February 15,
         2001, or which will become exercisable within 60 days after February
         15, 2001. Does not include options to purchase 456,667 shares of common
         stock which will become exercisable more than 60 days after February
         15, 2001.

(7)      Includes 15,000 shares of common stock held directly by Dr. Bransome
         and 2,500 shares of common stock held by Dr. Bransome's wife (of which
         he disclaims beneficial ownership). Does not include an option to
         purchase 20,000 shares of common stock which will become exercisable
         more than 60 days after February 15, 2001.

(8)      Includes 102,071 shares of common stock subject to options that were
         exercisable as of February 15, 2001. Does not include options to
         purchase 19,996 shares of common stock which will become exercisable
         more than 60 days after February 15, 2001.

(9)      Includes 12,467 shares of common stock and 62,535 shares of common
         stock subject to options which were exercisable as of February 15,
         2001, or which will become exercisable within 60 days after February
         15, 2001. Does not include options to purchase 19,996 shares of common
         stock which will become exercisable more than 60 days after February
         15, 2001.

(10)     Includes 46,067 shares of common stock subject to options which were
         exercisable as of February 15, 2001, or which will become exercisable
         within 60 days after February 15, 2001. Does not include an option to
         purchase 20,000 shares of common stock which will become exercisable
         more than 60 days after February 15, 2001.

(11)     Includes 5,000 shares of common stock held directly by Dr. Naimark,
         4,000 shares held jointly by Dr. Naimark and his wife and 13,337 shares
         of common stock subject to options which were exercisable as of
         February 15, 2001, or which will become exercisable within 60 days
         after February 15, 2001. Does not include an option to purchase 20,000
         shares of common stock which will become exercisable more than 60 days
         after February 15, 2001.

(12)     Includes 258,542 shares of common stock subject to options which were
         exercisable as of February 15, 2001, or which will become exercisable
         within 60 days after February 15, 2001, and 2,000 shares of common
         stock held by Ms. O'Dell's husband. Does not include options to
         purchase 108,958 shares of common stock which will become exercisable
         more than 60 days after February 15, 2001.

(13)     Includes 37,084 shares of common stock subject to options which were
         exercisable as of February 15, 2001, or which will become exercisable
         within 60 days after February 15, 2001. Does not include options to
         purchase 287,916 shares of common stock which will become exercisable
         more than 60 days after February 15, 2001.

(14)     Includes 1,900,968 shares of common stock subject to options which were
         exercisable as of February 15, 2001, or which will become exercisable
         within 60 days after February 15, 2001.

                                       17
   18
                          APPROVAL OF AMENDMENT TO OUR
                      RESTATED CERTIFICATE OF INCORPORATION
           TO INCREASE THE AUTHORIZED NUMBER OF SHARES OF COMMON STOCK
                   FROM 40,000,000 SHARES TO 80,000,000 SHARES

       The Board of Directors has adopted a resolution recommending that the
stockholders consider and adopt at the meeting an amendment to Article FOURTH of
Alteon's Restated Certificate of Incorporation. The proposed amendment would
increase the number of authorized shares of common stock, $.01 par value per
share, from 40,000,000 to 80,000,000 shares.

       For the reasons described below, the Board of Directors believes that the
proposed amendment is in the best interests of Alteon and its stockholders. If
the amendment is approved, it will become effective upon the filing of a
Certificate of Amendment to the Restated Certificate of Incorporation with the
Secretary of State of Delaware. The text of the proposed amended Article FOURTH
is set forth below:

          FOURTH: The total number of shares of all classes of stock which the
       Corporation shall have authority to issue is 81,993,329 shares. The
       Corporation is authorized to issue two classes of stock designated
       "Common Stock" and "Preferred Stock," respectively. The total number of
       shares of Common Stock authorized to be issued by the Corporation is
       80,000,000, and each such share of Common Stock shall have a par value of
       $.01 per share. The total number of shares of Preferred Stock authorized
       to be issued by the Corporation is 1,993,329 and each such share shall
       have a par value of $.01 per share."

       The Board of Directors believes that it is in the best interests of
Alteon to increase our authorized common stock in order to meet possible
contingencies and opportunities for which the issuance of common stock may be
deemed advisable. From time to time we have given, and in the future are likely
to give, consideration to the feasibility of obtaining funds for appropriate
corporate objectives, such as advancement of our research and drug development
programs, through the public or private sale of equity securities. The ability
to issue additional shares of common stock in any future capital raising
endeavor or expansion transaction, without the costs and delays incident to
obtaining stockholder approval at the time of such issuance, is vital to our
success in a competitive marketplace.

       We have no current plans and have not entered into any arrangements or
understandings whereby we would be required to issue any of the additional
shares of common stock for which authority is now sought. However, the number of
shares of common stock which we are required to issue upon the conversion of our
outstanding Series G Preferred Stock and Series H Preferred Stock varies with
the market price of the common stock. Therefore, depending on the market price
of our common stock, these additional shares may be issued upon the conversion
of currently outstanding convertible securities and the exercise of currently
outstanding warrants. Because of this variability, we agreed with the purchasers
of our common stock and warrants in a private placement in September 2000 to
request our stockholders to approve this proposed increase in our authorized
common stock.

       Other purposes for which the additional shares of common stock could be
issued include financing transactions, the acquisition of the shares or assets
of other corporations, stock splits or dividends, dividend reinvestment programs
and employee benefit plans.

       As of December 31, 2000, there were 22,399,660 shares of common stock
issued and outstanding. We have reserved additional shares of common stock in
connection with the conversion of our outstanding preferred stock, the exercise
of outstanding warrants and the exercise of options granted under our Amended
and Restated 1987 Stock Option Plan and Amended 1995 Stock Option Plan. In the
opinion of the Board of Directors, the remaining authorized and unissued shares
of common stock are insufficient to meet our capital needs.

       The newly authorized shares of common stock, which will be identical to
the shares of common stock presently authorized, may be issued for such
consideration as shall be authorized from time to time by the Board of
Directors, subject to any required regulatory approvals, but without further
action by the stockholders unless specifically required by applicable law or
rules of the American Stock Exchange or any other exchange or market system on
which the

                                       18
   19
common stock is then traded. In connection with any issuance and sale of such
shares, the number of shares to be issued and sold and the terms upon which they
may be issued and sold will necessarily be determined by conditions existing at
the time of such issuance and sale.

       Our stockholders do not have preemptive rights to subscribe on a pro rata
basis to any future issuance of shares. If Alteon elects to issue additional
shares of common stock, stockholders would not have any preferential right to
purchase them, and their ownership would therefore be diluted. Although the
Board is not aware of any effort by any person to acquire control of Alteon, the
authorized but unissued shares could be used to make it more difficult to effect
a change in control, and thereby make it more difficult for stockholders to
obtain an acquisition premium for their shares or remove incumbent management.
Such shares could be used to create impediments for persons seeking to gain
control of Alteon by means of a merger, tender offer, proxy contest or other
means. For example, substantial dilution of a potential acquiring party could be
achieved through private placement of securities with purchasers who might
cooperate with the Board of Directors in opposing the potential acquiring party.
The amendment is not part of a plan by our Board of Directors to propose a
series of new anti-takeover measures and the Board of Directors does not
presently intend to propose additional anti-takeover measures in future proxy
solicitations.

       In accordance with the Delaware Corporation Act, the proposed amendment
to the Restated Certificate of Incorporation must be approved by the affirmative
vote of the holders of at least a majority of the outstanding shares of our
common stock.

       THE BOARD OF DIRECTORS RECOMMENDS A VOTE FOR THE PROPOSED AMENDMENT TO
THE RESTATED CERTIFICATE OF INCORPORATION TO INCREASE THE NUMBER OF AUTHORIZED
SHARES OF COMMON STOCK FROM 40,000,000 TO 80,000,000 SHARES.

           RATIFICATION OF AMENDMENT TO INCREASE THE AUTHORIZED SHARES
                     FOR THE AMENDED 1995 STOCK OPTION PLAN

       Our Board of Directors has approved an amendment to Alteon's Amended 1995
Stock Option Plan (the "Plan") to increase the number of available shares of
common stock from four million to seven million. At December 31, 2000, options
to purchase 3,369,635 shares were outstanding under the Plan, leaving 420,207
shares available for grant. In the event that any option under the Plan expires
or is terminated without having been exercised in full, the shares of common
stock allocable to the unexercised portion of such option may again be subjected
to an option under the Plan. At December 31, 2000, the market value of the
common stock underlying the options was $3.4375 per share.

       The Plan was adopted by the Board of Directors in February 1995 and
ratified by the stockholders of Alteon in June 1995. Directors, officers,
employees and consultants of Alteon or any of its subsidiaries or affiliates are
eligible to receive options pursuant to the terms of the Plan. Alteon currently
has 7 directors, 3 officers (one of whom is also a director) and approximately
34 employees (including the officers). Alteon also engages consultants from time
to time. The Board believes that providing selected persons with the opportunity
to invest in Alteon will give them additional incentive to increase their
efforts on behalf of Alteon and will enable us to attract and retain the best
available employees, officers, directors and consultants. An increase in the
number of shares available under the Plan is necessary to provide sufficient
shares to achieve this goal.

       Stockholder approval of the amendment to the Plan is being sought (i) to
satisfy Section 422 of the Internal Revenue Code of 1986, as amended (the
"Code") which requires stockholder approval of amendment of the Plan in order
that options granted under the Plan may qualify as incentive stock options
("ISOs") and thus be entitled to receive special tax treatment under the Code,
and (ii) to satisfy the rules of the American Stock Exchange regarding
stockholder approval of grants of options to officers, directors and key
employees.

       Options granted under the Plan may be either ISOs as defined in Section
422 of the Code, or non-qualified stock options ("NQSOs"). ISOs may be granted
only to employees of Alteon and are subject to the following limitations, in
addition to restrictions applicable to all stock options under the Plan: (1) an
ISO may not be granted to an employee who at the time of grant owns in excess of
10% of the outstanding common stock of Alteon, unless the exercise price under
the option is at least 110% of the fair market value of the stock subject to the
option as of the date of grant of the

                                       19
   20
option and the option term is no more than five years, (2) the aggregate fair
market value (determined as of the time the option is granted) of stock with
respect to which ISOs are exercisable for the first time by an optionee during
any calendar year (under all option plans of Alteon) may not exceed $100,000,
(3) the exercise price of an ISO must be the fair market value of the stock at
the time the option is granted, (4) ISOs may not be sold, pledged or otherwise
transferred other than by will or by the laws of descent and distribution, and
(5) in the event of termination of an ISO holder's employment with Alteon, any
ISOs which are then exercisable must be exercised within three months of such
termination (or within twelve months if the termination is the result of death
or disability).

       Options that do not meet the above qualifications will be treated as
NQSOs.

Terms of the Plan

       Administration of the Plan. With respect to grants of options to
employees or consultants who are also officers or directors of Alteon, the Plan
is administered in compliance with Rule 16b-3 under the Securities Exchange Act
of 1934 by (1) the Board of Directors of Alteon, or (2) a committee comprised of
disinterested directors of Alteon who are not compensated as employees or
consultants, as designated by the Board. With respect to grants of options to
employees or consultants who are neither directors nor officers of Alteon, the
Plan is administered by (1) the Board, or (2) a committee designated by the
Board.

       The Plan may be administered by multiple administrative bodies.
Presently, the Plan is administered by a committee of non-compensated directors.
The Board or a committee designated by the Board, as the case may be, shall, in
its capacity as administrator, be hereinafter referred to as the
"Administrator."

       Granting of Options. Except with respect to non-compensated directors,
the granting of options to eligible participants is within the sole discretion
of the Administrator. Non-compensated directors receive grants of options in
accordance with a formula award structure pursuant to which they automatically
receive, upon the date of their election or re-election to the Board and on the
dates of the two Annual Meetings of Stockholders following their election or
re-election to the Board (subject to their continued service on the Board of
Directors), a stock option to purchase 20,000 shares of common stock (subject to
adjustment if they received stock options upon appointment to the Board between
Annual Meetings of Stockholders to fill a vacancy or newly created directorship)
at an exercise price equal to the fair market value of the common stock on the
date of grant. Each of these options will vest and become exercisable on the
date of Alteon's first Annual Meeting of Stockholders following the date of
grant, subject to the director's continued service on the Board. We do not
receive any consideration upon the grant of an option under the Plan.

       Option Agreement; Additional Functions of the Administrator. Options
granted pursuant to the Plan will be evidenced by agreements in such form as the
Administrator approves. In addition to the functions otherwise discussed in this
Proxy Statement, and excepting options granted to non-compensated directors, the
Administrator shall determine, subject to the terms and conditions of the Plan,
(1) whether and to whom options are to be granted, (2) whether an option is to
be an ISO or a NQSO, (3) the number of the shares covered by an option, (4) the
exercise price of an option, and (5) all other terms and conditions of an
option.

       Exercise Price. The exercise price of an NQSO is determined by the
Administrator. As discussed above, the exercise price of an ISO is determined
with respect to the applicable provisions of the Code. With respect to
non-compensated directors, the exercise price pursuant to the formula awards is
the fair market value of the shares at the time that the option is granted.

       Vesting; Term of Option. Except with respect to non-compensated
directors, the Administrator has the power to set the time or times during which
each option will vest and become exercisable, provided that no option may be
exercisable after the expiration of ten years from the date it is granted and no
ISO granted to a holder of ten percent of the total voting power of Alteon may
be exercisable after the expiration of five years from the date it is granted.
Options granted to non-compensated directors vest and become exercisable on the
date of Alteon's first Annual Meeting of Stockholders following the date of
grant, subject to the director's continued service on the Board.

       Transferability. Unless the Administrator determines otherwise, options
may not be sold or otherwise transferred

                                       20
   21
other than by will or by the laws of the descent and distribution and during the
lifetime of the optionee shall be exercisable only by the optionee. If the
Administrator so determines, subject to compliance with certain provisions set
forth in the Plan, NQSOs may be transferable to certain family members and
related trusts and partnerships.

       Duration of the Plan and Amendment. Options may be granted under the Plan
from time to time until February 28, 2005. The Administrator may at any time
terminate or amend the Plan, provided that (i) stockholder approval must be
obtained for any amendment for which such approval is required by applicable
laws or regulations, and (ii) no amendment can be made which would impair the
rights of any optionee under any grant theretofore made without the consent of
the optionee.

       Adjustments. Appropriate adjustments will be made in the number of shares
of stock covered by the Plan or subject to options granted under the Plan, and
in the exercise price per share of such options, in the event that the number of
outstanding shares of common stock is changed by a stock dividend, stock split,
reverse stock split, combination, reclassification or similar change in the
capital structure of Alteon without consideration.

       In the event of a merger or consolidation in which the stockholders of
Alteon prior to the merger own at least fifty percent of the voting power of
Alteon or the surviving entity after the merger or consolidation, each optionee
shall be entitled to receive upon exercise of the option, in lieu of the shares
for which the option was exercisable immediately before such transaction, the
number and class of securities to which such holder would have been entitled if
the option had been exercised immediately prior to the transaction.

       In the event of a dissolution or liquidation of Alteon, a merger or
consolidation in which the stockholders of Alteon prior to the merger do not own
at least fifty percent of the voting power of Alteon or the surviving entity
after the merger or consolidation, a transaction in which 100% of the voting
shares of Alteon is sold or otherwise transferred, or the sale of substantially
all of the assets of Alteon, (a) on the effective date of such transaction
holders of options will be entitled to receive upon exercise of the option, in
lieu of the shares for which the option was exercisable immediately before such
transaction, the number and class of securities to which such holder would have
been entitled if the option had been exercised immediately prior to the
transaction, (b) the Administrator may accelerate the time for exercise of some
or all then unexercised and unexpired options, or (c) the Administrator may
cancel all outstanding options as of the effective date of the transaction,
provided that notice of such cancellation is given to each optionee and each
optionee has the opportunity to exercise the option to the extent then
exercisable.

Certain Federal Income Tax Consequences

       The following summary discusses certain of the federal income tax
consequences associated with options granted under the Plan. This description of
tax consequences is based upon present federal tax laws and regulations and does
not purport to be a complete description of the federal income tax consequences
applicable to an optionee under the Plan. Accordingly, each optionee should
consult with his or her own tax advisor regarding the federal, state and local
tax consequences of the grant of an option and any subsequent exercise and
whether any action is appropriate.

       Non-Qualified Stock Options. There are no federal income tax consequences
associated with the grant of a NQSO. Upon the exercise of a NQSO, the optionee
generally must recognize ordinary compensation income equal to the "spread"
between the exercise price and the fair market value of our common stock on the
date of exercise. Any gain realized on disposition of shares purchased upon
exercise of the NQSO will be treated as capital gain for federal income tax
purposes.

       Incentive Stock Options. There will be no regular federal income tax
liability upon the grant or exercise of an ISO. However, the "spread" between
the exercise price and the fair market value of our common stock on the date of
exercise will be treated as a tax preference item for federal income tax
purposes and may subject the optionee to the alternative minimum tax in the year
of exercise.

       Any gain realized on disposition of shares purchased upon exercise of an
ISO will be treated as long-term capital gain for federal income tax purposes if
such shares are held for at least 12 months after the date of the issuance of
the shares pursuant to the exercise of the ISO and are disposed of at least two
years after the date of grant of the ISO. If the

                                       21
   22
shares are disposed of within 12 months after the date of issuance of the shares
or within two years after the date of grant of the ISO, the optionee will
recognize compensation income (taxable at ordinary income rates) to the extent
of the excess, if any, of the fair market value of such shares on the date of
exercise over the exercise price of the ISO, and capital gains on the excess,
if any, of the fair market value of such shares on the date of disposition over
the fair market value of such shares on the date of exercise.

       Compensation Deduction. To the extent compensation income is recognized
by an optionee in connection with the exercise of a NQSO or a "disqualifying
disposition" of stock obtained upon exercise of an ISO, Alteon generally would
be entitled to a matching compensation deduction (assuming the requisite
withholding requirements are satisfied).

       As of December 31, 2000, we had granted options to purchase an aggregate
of 3,602,193 shares of common stock (net of cancellations) under the Plan at an
average exercise price of $2.83 per share. As of February 15, 2001, options to
purchase 2,130,169 shares of common stock were exercisable and options to
purchase 217,558 shares of common stock had been exercised under the Plan. Each
of the two nominees for election to the Board of Directors, upon election to the
Board of Directors and on the dates of the two Annual Meetings of Stockholders
following their election to the Board (subject to their continued service on the
Board of Directors), will receive a stock option to purchase 20,000 shares of
common stock at an exercise price equal to the fair market value of the common
stock on the date of grant. See "Election of Directors - Compensation of
Directors."

         As of December 31, 2000, the following persons or groups had received
options to purchase shares of common stock under the Plan as follows: (i) the
Chief Executive Officer and Named Officers: Kenneth I. Moch, 1,165,000 shares;
Elizabeth A. O'Dell, 317,500 shares; Robert C. deGroof, 325,000 shares: (ii) all
current executive officers of Alteon as a group: 1,807,500 shares: (iii) each
nominee for director: Marilyn Breslow, 54,867 shares; Alan J. Dalby, 54,867
shares: (iv) all current employees, including all current officers who are not
executive officers, as a group: 624,422 shares.

       THE BOARD OF DIRECTORS RECOMMENDS THAT STOCKHOLDERS VOTE FOR THE
RATIFICATION OF THE AMENDMENT TO OUR AMENDED 1995 STOCK OPTION PLAN THEREBY
INCREASING THE NUMBER OF AVAILABLE SHARES FROM FOUR MILLION TO SEVEN MILLION.

          RATIFICATION OF APPOINTMENT OF INDEPENDENT PUBLIC ACCOUNTANTS

       The Board of Directors, subject to stockholder ratification, retained
Arthur Andersen LLP to serve as our independent public accountants for the
fiscal year ending December 31, 2001 because it is an internationally recognized
accounting firm familiar with the unique accounting, tax and financial issues
that relate to and affect the biopharmaceutical industry. Arthur Andersen LLP
has a firm-wide effort and a group of personnel that specialize in this industry
and has assigned members of this group to work with us. Arthur Andersen LLP also
served as our independent public accountants for the fiscal year ended December
31, 2000. One or more representatives of Arthur Andersen LLP is expected to
attend the meeting and have an opportunity to make a statement and/or respond to
appropriate questions from stockholders.

       Audit Fees

          The aggregate fees billed to Alteon by Arthur Andersen LLP for the
review of our annual financial statements, and the financial statements included
in our quarterly reports on Form 10Q, for the fiscal year ended December 31,
2000 totaled $45,000.

       Financial Information Systems Design and Implementation Fees

       We did not engage Arthur Andersen LLP to provide advice to us regarding
financial information systems design and implementation during the fiscal year
ended December 31, 2000.

       All Other Fees

       The aggregate fees billed to Alteon by Arthur Andersen LLP during the
fiscal year ended December 31, 2000 for non-audit services (including tax
related services), totaled $15,000. The Audit Committee has considered whether
or not the provision of non-audit services is compatible with maintaining Arthur
Anderson LLP's independence.

                                       22
   23
       THE BOARD OF DIRECTORS RECOMMENDS A VOTE FOR THE RATIFICATION OF THE
APPOINTMENT OF ARTHUR ANDERSEN LLP AS THE INDEPENDENT PUBLIC ACCOUNTANTS OF
ALTEON FOR THE FISCAL YEAR ENDING DECEMBER 31, 2001.


                       SECTION 16(a) BENEFICIAL OWNERSHIP
                              REPORTING COMPLIANCE

       Section 16(a) of the Securities Exchange Act of 1934, as amended,
requires our officers and directors, and persons who own more than 10% of a
registered class of our equity securities, to file reports of ownership and
changes in ownership on Forms 3, 4 and 5 with the Securities and Exchange
Commission ("SEC"). Officers, directors and greater than 10% stockholders are
required by SEC regulation to furnish Alteon with copies of all Forms 3, 4 and 5
they file.

       Based solely on our review of the copies of such forms we have received
and written representations from certain reporting persons that they were not
required to file Forms 5 for specified fiscal years, we believe that all our
officers, directors, and greater than 10% beneficial owners complied with all
filing requirements applicable to them with respect to transactions during
fiscal 2000.

                             STOCKHOLDERS' PROPOSALS

       Stockholders deciding to submit proposals for inclusion in our proxy
statement and form of proxy relating to the 2002 Annual Meeting of Stockholders
must advise the Secretary of Alteon of such proposals in writing by December 20,
2001. Any stockholder intending to propose a matter at the 2002 Annual Meeting
of Stockholders, but not intending for Alteon to include the matter in its proxy
statement or form of proxy relating to such meeting, must advise the Secretary
of Alteon of such intention in writing not later than 20 days prior to such
meeting. If Alteon does not receive such notice by that date, the notice will
be considered untimely. Our proxy for the 2002 Annual Meeting of Stockholders
will grant discretionary authority to the persons named therein to exercise
their voting discretion with respect to any manner of which Alteon does not
receive notice by March 5, 2002.

                                  OTHER MATTERS

       The Board of Directors is not aware of any matter to be presented for
action at the meeting other than the matters referred to above and does not
intend to bring any other matters before the meeting. However, if other matters
should come before the meeting, it is intended that holders of the proxies will
vote thereon in their discretion.

                                     GENERAL

       The accompanying proxy is solicited by and on behalf of the Board of
Directors of Alteon, whose notice of meeting is attached to this Proxy
Statement, and the entire cost of such solicitation will be borne by Alteon.

       In addition to the use of the mails, proxies may be solicited by personal
interview, telephone and telegram by directors, officers and other employees of
Alteon who will not be specially compensated for these services. The Company has
retained the services of Registrar and Transfer Company to assist in the proxy
solicitation at a fee estimated to be $17,500. We will also request that
brokers, nominees, custodians and other fiduciaries forward soliciting materials
to the beneficial owners of shares held of record by such brokers, nominees,
custodians and other fiduciaries. We will reimburse such persons for their
reasonable expenses in connection therewith.

       Certain information contained in this Proxy Statement relating to the
occupations and security holdings of directors and officers of Alteon is based
upon information received from the individual directors and officers.

                                       23
   24
       ALTEON HAS FURNISHED, WITHOUT CHARGE, A COPY OF ITS REPORT ON FORM 10-K
FOR THE YEAR ENDED DECEMBER 31, 2000, INCLUDING FINANCIAL STATEMENTS AND
SCHEDULES THERETO BUT NOT INCLUDING EXHIBITS, TO EACH OF ITS STOCKHOLDERS OF
RECORD ON APRIL 9, 2001, AND WILL FURNISH TO EACH BENEFICIAL STOCKHOLDER SUCH
REPORT UPON WRITTEN REQUEST MADE TO THE SECRETARY OF THE COMPANY. A REASONABLE
FEE WILL BE CHARGED FOR COPIES OF REQUESTED EXHIBITS.

       PLEASE DATE, SIGN AND RETURN THE PROXY CARD AT YOUR EARLIEST CONVENIENCE
IN THE ENCLOSED RETURN ENVELOPE. A PROMPT RETURN OF YOUR PROXY CARD WILL BE
APPRECIATED, AS IT WILL SAVE THE EXPENSE OF FURTHER MAILINGS.


                                             By Order of the Board of Directors
                                             /s/ Elizabeth A. O'Dell
                                             ----------------------------------
                                             ELIZABETH A. O'DELL
                                             Secretary

Ramsey, New Jersey
__________, 2001

                                       24
   25
                                   APPENDIX I

                                   ALTEON INC.
                    AUDIT COMMITTEE OF THE BOARD OF DIRECTORS
                                     CHARTER


1.   Purpose

       The Audit Committee shall provide assistance to the Board of Directors in
fulfilling its responsibility to the stockholders, potential stockholders, and
investment community relating to the accounting and reporting practices of
Alteon Inc. (the "Corporation") and the quality and integrity of the financial
information provided by the Corporation. The Audit Committee will fulfill these
responsibilities and duties primarily by carrying out the activities enumerated
in this Charter.

2.   Composition

       The Audit Committee shall be comprised of three or more directors as
determined by the Board of Directors of the Corporation, each of whom shall be
independent directors, and free from any relationship that would interfere with
the exercise of his or her independent judgment as a member of the Audit
Committee. All members of the Audit Committee shall be financially literate as
interpreted by the Board of Directors, or become financially literate within a
reasonable period of time after his or her appointment to the Audit Committee.
One member of the Audit Committee shall have accounting or related financial
management expertise, as the Board of Directors interprets such qualifications
in its business judgment.

3.   Meetings

       The Audit Committee shall meet at stated times without notice, or on
notice to all by the Chairman or Vice Chairman of the Board of Directors, the
Chief Executive Officer, the President, the Chief Financial Officer, or by one
of the members of the Audit Committee, as frequently as circumstances and needs
of the Corporation shall dictate. As part of its responsibilities to foster open
communication, the Audit Committee should meet at least annually with management
and the independent accountants for the Corporation separately to discuss any
matters that the Audit Committee or each of these groups believe should be
discussed privately.

4.   Responsibilities and Duties

         To fulfill its responsibilities and duties the Audit Committee shall:

         a.       Review and reassess, at least annually, the adequacy of this
                  Charter. Make recommendations to the Board of Directors, as
                  conditions dictate, to update this Charter.

         b.       Review with management and the independent accountants the
                  Corporation's audited financial statements, including a
                  discussion with the independent accountants of the matters
                  required to be discussed by Statement of Auditing Standards
                  No. 61, "Communications with Audit Committees" ("SAS No. 61").

         c.       Recommend to the Board of Directors that, based on the Audit
                  Committee's review and discussions with management and the
                  independent accountants, the audited financial statements be
                  included in the annual report filing with the Securities and
                  Exchange Commission.

         d.       Review the performance of the independent accountants and make
                  recommendations to the Board of Directors regarding the
                  appointment of termination of the independent accountants. The
                  independent accountants are ultimately accountable to the
                  Board of Directors and the Audit Committee. The Audit
                  Committee and the Board of Directors have the ultimate
                  authority and responsibility to select, evaluate, and where
                  appropriate, replace the independent accountants.

                                       25
   26
         e.       Oversee independence of the accountants by:

                  1.       Receiving from the independent accountants, on a
                           periodic basis, a formal written statement
                           delineating all relationships between the independent
                           accountants and the Corporation consistent with
                           Independence Standard No. 1, "Independence
                           Discussions with Audit Committees."

                  2.       Discussing with the independent accountants any
                           disclosed relationships or services between the
                           independent accountants and the Corporation or any
                           other disclosed relationships or services that may
                           impact the objectivity and independence of the
                           accountants; and

                  3.       Recommending, if necessary, that the Board of
                           Directors take appropriate action to satisfy itself
                           of the accountants' independence based on the report
                           provided.

         f.       Review in consultation with the independent accountants the
                  audit scope and plan of the independent accountants.

         g.       Review with the independent accountants and management the
                  adequacy and effectiveness of internal controls of the
                  Corporation.

         h.       Report through the Audit Committee's Chairperson to the Board
                  of Directors following meeting of the Audit Committee.

         i.       Maintain minutes or other records of meetings and activities
                  of the Audit Committee.

         j.       Perform any other activities consistent with this Charter and
                  the Corporation's By-Laws as the Audit Committee or the Board
                  of Directors deems necessary or appropriate.

                                       26
   27
                                   APPENDIX II

                                   ALTEON INC.

                         AMENDED 1995 STOCK OPTION PLAN
                           (AS PROPOSED TO BE AMENDED)

         1. Purposes of Plan. The purposes of this Stock Option Plan are to
attract and retain the best available personnel for positions of substantial
responsibility, to provide additional incentive to Employees and Consultants of
the Company and its Subsidiaries and to promote the success of the Company's
business. Options granted under the Plan may be Incentive Stock Options or
Non-Qualified Stock Options, as determined by the Administrator at the time of
grant of an Option.

         2. Certain Definitions. As used herein, the following definitions shall
apply:

                  2.1. "Administrator" means the Board or a Committee.

                  2.2. "Board" means the Board of Directors of the Company.

                  2.3. "Code" means the Internal Revenue Code of 1986, as
         amended, and the regulations thereunder.

                  2.4. "Committee" means a Committee appointed by the Board in
         accordance with Section 4.1 of the Plan.

                  2.5. "Common Stock" means the Common Stock of the Company.

                  2.6. "Company" means Alteon Inc., a Delaware corporation.

                  2.7. "Consultant" means any person, including an advisor, who
         is engaged by the Company or any Subsidiary to render services and is
         compensated for such services. The payment of a director's fee by the
         Company shall not render a director a Consultant within the meaning of
         this section.

                  2.8. "Date of Grant" means the date on which an Option is
         granted under the Plan pursuant to Section 12 of the Plan.

                  2.9. "Employee" means any person, including officers and
         directors, employed by the Company or any Subsidiary of the Company.
         The payment of a director's fee by the Company shall not be sufficient
         to constitute employment by the Company.

                  2.10. "Exchange Act" means the Securities Exchange Act of
         1934, as amended.

                  2.11."Fair Market Value" means, as of any date, the value of
         the Common Stock determined as follows:

                           (a) If the Common Stock is listed on any established
                  stock exchange or a national market system including without
                  limitation the National Market System of the National
                  Association of Securities Dealers, Inc. Automated Quotation
                  ("NASDAQ") System, its Fair Market Value shall be the closing
                  sales price for such stock (or the closing bid, if no sales
                  were reported) as quoted on such system or exchange for such
                  date, or if such date is not a trading day, the last market
                  trading day prior to such date as reported in the Wall Street
                  Journal or such other source as the Administrator deems
                  reliable;

                           (b) If the Common Stock is quoted on the NASDAQ
                  System (but not on the National Market System thereof) or
                  regularly quoted by a recognized securities dealer but selling
                  prices are not reported, its Fair Market Value shall be the
                  mean between the high and low asked prices for the
   28
                  Common Stock as quoted on such System or by such dealer for
                  such date, or if such date is not a trading day for the last
                  market trading day prior to such date; or

                           (c) In the absence of an established market for the
                  Common Stock, the Fair Market Value thereof shall be
                  determined in good faith by the Administrator.

                  2.12. "Incentive Stock Option" means an Option which qualifies
         as an incentive stock option within the meaning of Section 422 of the
         Code.

                  2.13. "Non-Compensated Directors" means directors of the
         Company who are not Consultants who render services more than one (1)
         day per week or full-time Employees.

                  2.14. "Non-Qualified Stock Option" means an Option which does
         not qualify as an Incentive Stock Option.

                  2.15. "Option" means a stock option granted pursuant to the
         Plan.

                  2.16. "Option Agreement" means the agreement which must be
         entered into between the Optionee and the Company upon the grant of an
         Option by the Company to the Optionee as approved by the Administrator
         pursuant to Section 15 of the Plan.

                  2.17. "Optionee" means a person who receives an Option.

                  2.18. "Parent" means a "parent corporation", whether now or
         hereafter existing, as defined in Section 424(e) of the Code.

                  2.19. "Plan" means this 1995 Stock Option Plan.

                  2.20. "Share" means a share of the Common Stock, as adjusted
         in accordance with Section 11 of the Plan.

                  2.21. "Subsidiary" means a "subsidiary corporation", whether
         now or hereafter existing, as defined in Section 424(f) of the Code.

         3. Stock Subject to the Plan. Subject to the provisions of Section 11
of the Plan, the maximum aggregate number of Shares which may be optioned and
sold under the Plan is 7,000,000 Shares and the maximum number of Shares which
may be covered by Options granted to any employee in any calendar year may not
exceed 500,000 Shares. The Shares may be authorized, but unissued, or reacquired
Common Stock. If an Option should expire or become unexercisable for any reason
without having been exercised in full, the unpurchased Shares which were subject
thereto shall, unless the Plan shall have been terminated, become available for
future grant under the Plan.

         4. Administration of the Plan.

                  4.1.       Procedure.

                           (a) Administration With Respect to Directors and
                  Officers. With respect to grants of Options to Employees and
                  Consultants who are also officers or directors of the Company,
                  the Plan shall be administered, and grants of Options shall be
                  approved, by (i) the Board or (ii) a Committee designated by
                  the Board to administer the Plan, which Committee shall be
                  constituted in such a manner as (A) to permit transactions
                  under the Plan to qualify for exemption from the provisions of
                  Section 16(b) of the Exchange Act pursuant to Rule 16b-3
                  promulgated thereunder ("Rule 16b-3") and (B) to satisfy all
                  legal requirements relating to administration of stock option
                  plans and the Code (the "Applicable Laws"). Once appointed,
                  such Committee shall continue to serve in its designated
                  capacity until otherwise directed by the Board. From time to
                  time the Board may increase the size of the Committee and
                  appoint additional members thereof, remove members (with or
                  without cause) and appoint new
   29
                  members in substitution therefor, fill vacancies, however
                  caused, and remove all members of the Committee and thereafter
                  directly administer the Plan.

                           (b) Administration With Respect to Consultants and
                  Employees Who Are Not Directors or Officers. With respect to
                  grants of Options to Employees or Consultants who are neither
                  directors nor officers of the Company, the Plan shall be
                  administered by (i) the Board or (ii) a Committee designated
                  by the Board, which Committee shall be constituted in such a
                  manner as to satisfy the Applicable Laws. Once appointed, such
                  Committee shall continue to serve in its designated capacity
                  until otherwise directed by the Board. From time to time the
                  Board may increase the size of the Committee and appoint
                  additional members thereof, remove members (with or without
                  cause) and appoint new members in substitution therefor, fill
                  vacancies, however caused, and remove all members of the
                  Committee and thereafter directly administer the Plan, all to
                  the extent permitted by the Applicable Laws.

                           (c) Formula Awards to Non-Compensated Directors.

                                    (i) On the date of a Non-Compensated
                           Director's election or reelection to the Board at an
                           annual meeting of shareholders of the Company and on
                           each of the dates of the Company's two annual
                           meetings of shareholders following the date of such
                           election, (provided that on such date the
                           Non-Compensated Director is serving as a director of
                           the Company), such Non-Compensated Director shall be
                           granted a Non-Qualified Stock Option to purchase
                           20,000 Shares. Each such Option shall vest and become
                           exercisable on the date of the Company's first annual
                           meeting of shareholders following the date of its
                           grant, provided that on such date the Non-Compensated
                           Director is serving as a director of the Company.

                                    (ii) If a Non-Compensated Director is
                           elected or appointed to the Board other than at an
                           annual meeting of shareholders, on the date of his
                           election he shall be granted a Non-Qualified Stock
                           Option to purchase the number of Shares determined by
                           multiplying 1,667 by the number of whole or partial
                           months from the date of his election or appointment
                           to the Company's next annual meeting of shareholders.
                           For purposes of the preceding sentence, a month shall
                           mean a period of 30 consecutive days. In addition, on
                           the dates of each of the Company's annual meetings of
                           shareholders which occur during the term to which he
                           was so elected or appointed (provided that on such
                           date he is serving as a director of the Company),
                           such Non-Compensated Director shall be granted a
                           Non-Qualified Stock Option to purchase 20,000 Shares.
                           Each Option granted pursuant to this subsection
                           4.1(c)(ii) shall vest and become exercisable on the
                           date of the Company's first annual meeting of
                           shareholders following the date of its grant,
                           provided that on such date the Non-Compensated
                           Director is serving as a director of the Company.

                                    (iii) Each Non-Compensated Director who held
                           such office on January 1, 1999 shall be granted a
                           Non-Qualified Stock Option to purchase 3,667 Shares.
                           Each Non-Compensated Director who held such office on
                           January 1, 1999 and whose term continues beyond the
                           date of the Company's first annual meeting of
                           shareholders following January 1, 1999 shall be
                           granted a Non-Qualified Stock Option to purchase
                           8,800 Shares on the date of the Company's first
                           annual meeting of shareholders following January 1,
                           1999 (provided that on such date the Non-Compensated
                           Director is serving as a director of the Company).
                           Each Non-Compensated Director who held such office on
                           January 1, 1999 and whose term continues beyond the
                           date of the Company's second annual meeting of
                           shareholders following January 1, 1999 shall be
                           granted a Non-Qualified Stock Option to purchase
                           8,800 Shares on the date of the Company's second
                           annual meeting of shareholders following January 1,
                           1999 (provided that on such date the Non-Compensated
                           Director is serving as a director of the Company).
                           Each Option granted pursuant to this subsection
                           4.1(c)(iii) shall vest and become exercisable on the
                           date of the Company's first annual meeting of
                           shareholders following the date of its grant,
                           provided that on such date the Non-Compensated
                           Director is serving as a director of the Company.

                                    (iv) Options granted pursuant to this
                           Section 4.1(c) shall have a per share exercise price
                           equal to the Fair Market Value per share on the Date
                           of Grant and shall expire ten years from the Date of
                           Grant. Once an Option granted pursuant to this
                           Section, or any portion thereof, has become
                           exercisable, it shall remain exercisable regardless
                           of whether or not the Non-Compensated Director
                           holding the Option later ceases to be a director of
                           the Company.

                                    (v) If the granting of any option on the
                           dates provided in this Section 4.1(c) would cause the
                           number of Shares as to which options have been
                           granted pursuant to the Plan to exceed the number set
                           forth in Section 3 of the Plan, the grant of such
                           option shall be deferred to the first date on which
                           an option may
   30
                           be granted without exceeding the limitation set forth
                           in Section 3 and such date shall be the Date of Grant
                           of the option.

                           (d) Multiple Administrative Bodies. The Plan may be
                  administered by different bodies with respect to directors,
                  non-director officers, and Employees and Consultants who are
                  neither directors nor officers.

                  4.2. Powers of the Administrator. Subject to the provisions of
         the Plan and in the case of a Committee, the specific duties delegated
         by the Board to such Committee, the Administrator, acting in its sole
         discretion, shall have the power and authority to supervise the
         administration of the Plan and to take all action necessary or
         desirable in order to carry out the provisions of the Plan including,
         without limitation, the power and authority:

                           (a) to select the Consultants and Employees to whom
                  Options may from time to time be granted hereunder;

                           (b) to determine whether and to what extent Options
                  are granted hereunder;

                           (c) to determine the number of shares of Common Stock
                  to be covered by each such Option granted hereunder;

                           (d) to approve forms of agreement for use under the
                  Plan;

                           (e) to determine the terms and conditions, not
                  inconsistent with the terms of the Plan, of any Option granted
                  hereunder (including, but not limited to, the exercise price,
                  the vesting schedule, and any restrictions or limitations
                  regarding any Option and/or the Shares relating thereto) based
                  in each case on such factors as the Administrator shall
                  determine, in its sole discretion;

                           (f) to make changes to any outstanding Option,
                  including, without limitation, to reduce the exercise price,
                  to accelerate the vesting schedule, or to extend the
                  expiration date, provided that no such change shall impair the
                  rights of any Optionee under any grant previously made without
                  such Optionee's consent;

                           (g) to determine whether and when an Optionee has
                  ceased to have an employment or consulting relationship with
                  the Company;

                           (h) to buy out for a payment in cash or Shares, an
                  Option previously granted, based on such terms and conditions
                  as the Administrator shall establish and the Optionee shall
                  accept.

                  4.3. Effect of Committee's Decision. The Administrator shall
         have the power and authority to establish, amend, and revoke rules and
         regulations for administration of the Plan. All decisions,
         determinations and interpretations of the Administrator shall be final
         and binding on all holders of Options.

         5. Eligibility. Non-Qualified Stock Options may be granted to
Non-Compensated Directors (but only pursuant to Section 4.1(c)), Employees, and
Consultants. Incentive Stock Options may be granted only to Employees. An
individual who has been granted an Option may, if otherwise eligible, be granted
an additional Option or Options.

         6. Term of Plan. The Plan shall become effective upon the earlier to
occur of its adoption by the Board of Directors or its approval by the
shareholders of the Company as described in Section 18 of the Plan. It shall
continue in effect for a term of ten (10) years unless sooner terminated under
Section 13 of the Plan.

         7. Exercise Period of Option.

                  7.1. Term. Each Option shall vest and become exercisable as
         provided in the Option Agreement. The term of each Option shall be the
         term stated in the Option Agreement; provided, however, that in no case
         shall the term shall be more than ten (10) years from the Date of
         Grant. However, in the case of an Incentive
   31
         Stock Option granted to an Optionee who, at the time the Option is
         granted, owns stock representing more than ten percent (10%) of the
         voting power of all classes of stock of the Company or any Parent or
         Subsidiary, the term of the Option shall be no more than five (5) years
         from the Date of Grant.

                  7.2. Termination of Employment. If an Optionee ceases to be an
         Employee of the Company for any reason, except death or disability
         within the meaning of Section 422(c) of the Code, an Incentive Stock
         Option, to the extent unexercised and exercisable by the Optionee on
         the date on which the Optionee ceased to be an Employee, may be
         exercised by the Optionee within three (3) months after the date on
         which the Optionee's employment terminated, but in any event no later
         than the date of expiration of the Option term. If the Optionee's
         employment is terminated because of the death or disability of the
         Optionee within the meaning of Section 422(c) of the Code, an Incentive
         Stock Option, to the extent unexercised and exercisable by the Optionee
         on the date on which the Optionee ceased to be an Employee, may be
         exercised by the Optionee (or the Optionee's legal representative) at
         any time prior to the expiration of twelve (12) months from the date
         the Optionee's employment terminated, but in any event no later than
         the date of expiration of the Option term. An Optionee's employment
         shall be deemed to have terminated on account of death if the Optionee
         dies within three (3) months after the Optionee's termination of
         employment.

         8. Option Exercise Price and Consideration.

                  8.1. Exercise Price. The per Share exercise price for the
         Shares to be issued pursuant to exercise of an Option (other than
         Options granted pursuant to Section 4.1(c)) shall be such price as is
         determined by the Administrator, provided that in the case of an
         Incentive Stock Option (a) granted to an Employee who, at the time of
         the grant of such Incentive Stock Option, owns stock representing more
         than ten percent (10%) of the voting power of all classes of stock of
         the Company or any Parent or Subsidiary, the per Share exercise price
         shall be no less than 110% of the Fair Market Value per Share on the
         Date of Grant and (b) granted to any other Employee, the per Share
         exercise price shall be no less than 100% of the Fair Market Value per
         Share on the Date of Grant.

                  8.2. Consideration. The consideration to be paid for the
         Shares to be issued upon exercise of an Option, including the method of
         payment, shall be determined by the Administrator and may consist
         entirely of (i) cash, (ii) check, (iii) promissory note, (iv) other
         Shares which have a Fair Market Value on the date of surrender equal to
         the aggregate exercise price of the Shares as to which said Option
         shall be exercised, (v) authorization from the Company to retain from
         the total number of Shares as to which the Option is exercised that
         number of Shares having a Fair Market Value on the date of exercise
         equal to the exercise price for the total number of Shares as to which
         the Option is exercised, (vi) delivery of a properly executed exercise
         notice together with irrevocable instructions to a broker to deliver
         promptly to the Company the amount of sale or loan proceeds required to
         pay the exercise price, (vii) any combination of the foregoing methods
         of payment, or (viii) such other consideration and method of payment
         for the issuance of Shares to the extent permitted under the Applicable
         Laws.


         9. Exercise of Option.

                  9.1. Procedure for Exercise. An Option shall be deemed to be
         exercised when written notice of such exercise has been given to the
         Company in accordance with the terms of the Option Agreement by the
         person entitled to exercise the Option and full consideration for the
         Shares with respect to which the Option is exercised has been received
         by the Company. Until the issuance (as evidenced by the appropriate
         entry on the books of the Company or of a duly authorized transfer
         agent of the Company) of the stock certificate evidencing such Shares,
         no right to vote or receive dividends or any other rights as a
         shareholder shall exist with respect to the Optioned Stock,
         notwithstanding the exercise of the Option. The Company shall issue (or
         cause to be issued) such stock certificate promptly upon exercise of
         the Option. No adjustment will be made for a dividend or other right
         for which the record date is prior to the date the stock certificate is
         issued. An Option may not be exercised for a fraction of a Share.

                  9.2. Limitations on Exercise.

                           (a) Shares shall not be issued pursuant to the
                  exercise of an Option unless the exercise of such Option and
                  the issuance and delivery of such Shares pursuant thereto
                  shall comply with all relevant provisions of law, including,
                  without limitation, the Securities Act of 1933, as amended,
                  the Exchange Act, the rules
   32
                  and regulations promulgated thereunder, and the requirements
                  of the National Association of Securities Dealers or any stock
                  exchange upon which the Shares may then be listed, and shall
                  be further subject to the approval of counsel for the Company
                  with respect to such compliance. As a condition to the
                  exercise of an Option, the Company may require the person
                  exercising such Option to represent and warrant at the time of
                  any such exercise that the Shares are being purchased only for
                  investment and without any present intention to sell or
                  distribute such Shares if, in the opinion of counsel for the
                  Company, such a representation is required by any of the
                  aforementioned relevant provisions of law.

                           (b) The Administrator may specify a reasonable
                  minimum number of shares that may be purchased on any exercise
                  of an Option, provided that such minimum number will not
                  prevent the Optionee from exercising that full number of
                  Shares as to which the Option is then exercisable.

                  9.3. Withholding Obligations. Prior to issuance of the Shares
         upon exercise of an Option, the Optionee shall pay or make adequate
         provision for any federal or state withholding obligations of the
         Company, if applicable, in a form and manner satisfactory to the
         Administrator.


         10. Transferability of Options. Except as otherwise provided in this
Section 10, Options may not be sold, pledged, assigned, hypothecated,
transferred or disposed of in any manner other than by will or by the laws of
descent and distribution and during the lifetime of the Optionee shall be
exercisable only by the Optionee. If the Administrator so determines,
Non-Qualified Stock Options may be transferable to (a) the Optionee's spouse,
parents, siblings, children or grandchildren (including stepparents,
stepsiblings, stepchildren, and stepgrandchildren), (b) trusts for the benefit
of the Optionee and/or such family members, and (c) partnerships whose only
partners are the Optionee and/or such family members, provided that (i) no
consideration is paid for such transfer, (ii) the terms and conditions of the
Option which are applicable to the Optionee prior to the transfer of the Option
shall continue to apply to the transferee; and (iii) the Option Agreement
pertaining to each transferable option shall set forth the applicable transfer
restrictions.

         11. Adjustments. Unless the terms of an Option Agreement provide
otherwise:

                  11.1. Change in Capitalization. Subject to any required action
         by the shareholders of the Company, the number of shares of Common
         Stock covered by each outstanding Option, and the number of shares of
         Common Stock which have been authorized for issuance under the Plan but
         as to which no Options have yet been granted or which have been
         returned to the Plan upon cancellation or expiration of an Option, as
         well as the price per share of Common Stock covered by each such
         outstanding Option, shall be proportionately adjusted for any increase
         or decrease in the number of issued shares of Common Stock resulting
         from a stock split, reverse stock split, stock dividend, combination or
         reclassification of the Common Stock, or any other increase or decrease
         in the number of issued shares of Common Stock effected without receipt
         of consideration by the Company; provided, however, that conversion of
         any convertible securities of the Company shall not be deemed to have
         been "effected without receipt of consideration." Such adjustment shall
         be made by the Administrator, whose determination in that respect shall
         be final, binding and conclusive. Except as expressly provided herein,
         no issuance by the Company of shares of stock of any class, or
         securities convertible into shares of stock of any class, shall affect,
         and no adjustment by reason thereof shall be made with respect to, the
         number or price of shares of Common Stock subject to an Option.


                  11.2. Merger without Change of Control. After a merger of one
         or more corporations or other entities with or into the Company or
         after a consolidation of the Company and one or more corporations or
         other entities in which the shareholders of the Company immediately
         prior to such merger or consolidation own after such merger or
         consolidation shares representing at least fifty percent (50%) of the
         voting power of the Company or the surviving or resulting corporation
         or other entity, as the case may be, each holder of an outstanding
         Option shall, at no additional cost, be entitled upon exercise of such
         Option to receive in lieu of the shares of Common Stock as to which
         such Option was exercisable immediately prior to such event, the number
         and class of shares of stock or other securities, cash or property
         (including, without limitation, shares of stock or other securities of
         another corporation or Common Stock) to which such holder would have
         been entitled pursuant to the terms of the agreement of merger or
         consolidation if, immediately prior to such merger or consolidation,
         such holder had been the holder of record of a number of shares of
         Common Stock equal to the number of shares for which such Option shall
         be so exercised.
   33
                  11.3. Sale or Merger with Change of Control. If the Company is
         merged with or into or consolidated with another corporation or other
         entity under circumstances where the shareholders of the Company
         immediately prior to such merger or consolidation do not own after such
         merger or consolidation shares representing at least fifty percent of
         the voting power of the Company or the surviving or resulting
         corporation or other entity, as the case may be, or if one hundred
         percent of the then outstanding voting shares of the Company are sold
         or otherwise transferred, or if the Company is liquidated, or sells or
         otherwise disposes of substantially all of its assets to another
         corporation or other entity while unexercised Options remain
         outstanding under the Plan, (a) subject to the provisions of clause (c)
         below, after the effective date of such merger, consolidation,
         liquidation, sale or disposition, as the case may be, each holder of an
         outstanding Option shall be entitled, upon exercise of such Option, to
         receive, in lieu of the shares of Common Stock as to which Option was
         exercisable immediately prior to such event, the number and class of
         shares of stock or other securities, cash or property (including,
         without limitation, shares of stock or other securities of another
         corporation or common stock) to which such holder would have been
         entitled pursuant to the terms of the merger, consolidation,
         liquidation, sale or disposition if, immediately prior to such event,
         such holder had been the holder of a number of shares of Common Stock
         equal to the number of shares as to which such Option shall be so
         exercised; (b) the Administrator may accelerate the time for exercise
         of some or all unexercised and unexpired options so that from and after
         a date prior to the effective date of such merger, consolidation,
         liquidation, sale or disposition, as the case may be, specified by the
         Administrator such accelerated options shall be exercisable in full; or
         (c) all outstanding Options may be cancelled by the Administrator as of
         the effective date of any such merger, consolidation, liquidation, sale
         or disposition provided that (i) notice of such cancellation shall be
         given to each holder of an Option and (ii) each holder of an Option
         shall have the right to exercise such Option to the extent that the
         same is then exercisable or, if the Administrator shall have
         accelerated the time for exercise of all unexercised and unexpired
         Options, in full during the 10-day period preceding the effective date
         of such merger, consolidation, liquidation, sale or disposition.

                  11.4. Miscellaneous. Adjustments under this Section 11 shall
         be determined by the Administrator, and such determinations shall be
         conclusive. No fractional shares of Common Stock shall be issued under
         the Plan on account of any adjustment specified above.

         12. Time of Granting Options. The Date of Grant of an Option shall, for
all purposes, be the date on which the Administrator makes the determination
granting such Option, or such other date as is determined by the Administrator.
Notice of the determination shall be given to each Employee or Consultant to
whom an Option is granted within a reasonable time after the date of such grant.

         13. Amendment and Termination of the Plan.

                  13.1. Amendment and Termination. The Board may at any time
         amend, alter, suspend or discontinue the Plan, but no amendment,
         alteration, suspension or discontinuation shall be made which would
         impair the rights of any Optionee under any grant theretofore made
         without the Optionee's consent. In addition, to the extent necessary
         and desirable to comply with Rule 16b-3 under the Exchange Act or with
         Section 422 of the Code (or any other applicable law or regulation,
         including the requirements of the National Association of Securities
         Dealers or an established stock exchange), the Company shall obtain
         shareholder approval of any Plan amendment in such a manner and to such
         a degree as required.

                  13.2. Effect of Amendment or Termination. Any such amendment
         or termination of the Plan shall not affect Options already granted and
         such Options shall remain in full force and effect as if the Plan had
         not been amended or terminated unless mutually agreed otherwise between
         the Optionee and the Board, which agreement must be in writing and
         signed by the Optionee and the Company.

         14. Reservation of Shares. The Company, during the term of the Plan,
will at all times reserve and keep available such number of Shares as shall be
sufficient to satisfy the requirements of the Plan. The inability of the Company
to obtain authority from any regulatory body having jurisdiction, which
authority is deemed by the Company's counsel to be necessary to the lawful
issuance and sale of any Shares hereunder, shall relieve the Company of any
liability in respect of the failure to issue or sell such Shares as to which
such requisite authority shall not have been obtained.
   34
         15. Agreements. Options shall be evidenced by written agreements in
such form as the Administrator shall approve from time to time. Each Option
shall be designated in the Option Agreement as either an Incentive Stock Option
or a Non-Qualified Stock Option as the Administrator shall determine. However,
notwithstanding such designations, to the extent that the aggregate Fair Market
Value of the Shares with respect to which Options designated as Incentive Stock
Options are exercisable for the first time by any Optionee during any calendar
year (under all plans of the Company or any Parent or Subsidiary) exceeds
$100,000, such excess Options shall be treated as Non-Qualified Stock Options.
For purposes of the preceding sentence, Incentive Stock Options shall be taken
into account in the order in which they were granted, and the Fair Market Value
of the Shares shall be determined as of the time the Option with respect to such
Shares is granted.

         16. No Additional Rights. The Plan shall not confer upon any Optionee
any right with respect to continuation of an employment or consulting
relationship with the Company, nor shall it interfere in any way with his right
or the Company's right to terminate his employment or consulting relationship at
any time, with or without cause.

         17. Rule 16b-3. Grants of Options to persons subject to Section 16(b)
of the Exchange Act must qualify for exemption from Section 16(b) of the
Exchange Act pursuant to Rule 16b-3. Options granted to such persons shall
contain such additional conditions or restrictions as may be required thereunder
to qualify for the maximum exemption from Section 16 of the Exchange Act with
respect to Plan transactions.

         18. Shareholder Approval. Continuance of the Plan shall be subject to
approval by the shareholders of the Company within twelve (12) months after the
date the Plan is adopted. Such shareholder approval shall be obtained in the
degree and manner required under applicable state and federal law.


                                   * * * * *

   35
                                 REVOCABLE PROXY
                                   ALTEON INC.


[ X ]  PLEASE MARK VOTES
       AS IN THIS EXAMPLE



PROXY SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS OF THE CORPORATION FOR THE
ANNUAL MEETING OF STOCKHOLDERS

  The undersigned hereby constitutes and appoints Kenneth I. Moch and Elizabeth
A. O'Dell and each of them, his or her true and lawful agents and proxies with
full power of substitution in each, to represent and to vote on behalf of the
undersigned all of the shares of Alteon Inc. (the "Company") which the
undersigned is entitled to vote at the Annual Meeting of Stockholders of the
Company to be held at the American Stock Exchange, 86 Trinity Place, New York,
New York at 9:00 A.M., local time, on June 5, 2001, and at any adjournment or
adjournments thereof, upon the following proposals more fully described in the
Notice of Annual Meeting of Stockholders and Proxy Statement for the Meeting
(receipt of which is hereby acknowledged).










    Please be sure to sign and date this Proxy in the box below

                                                                Dated:

Signature of Stockholder               Signature of Stockholder if held Jointly

1. ELECTION OF DIRECTORS.

(Mark one only) For All

Nominee: Marilyn G. Breslow and Alan J. Dalby

                                               For [ ]  Against [ ] Except [ ]

(INSTRUCTIONS: To withhold authority for any
individual nominee, write that nominee's name
in the space provided below.)

                                               For [ ] Against [ ] Abstain [ ]

2. Approval of the proposal to amend the
   Restated Certificate of Incorporation
   to increase the number of authorized
   shares from forty million to eighty million.

                                               For [ ] Against [ ] Abstain [ ]

3. Approval of the proposal to amend the
   1995 Stock Option Plan to increase the
   number of available shares from four
   million to seven million.

                                               For [ ] Against [ ] Abstain [ ]

4. Approval of the proposal to ratify the appoint-
   ment of Arthur Andersen LLP as Alteon's
   independent public accountants for the fiscal
   year ending  December 31, 2001.


5. In their discretion, the proxies are
   authorized to vote upon other matters as
   may properly come before the Meeting.


PLEASE CHECK BOX IF YOU PLAN
TO ATTEND THE ANNUAL MEETING.                                              [ ]


THIS PROXY WHEN PROPERLY EXECUTED WILL BE VOTED IN THE MANNER DIRECTED HEREIN BY
THE UNDERSIGNED STOCKHOLDER. IF NO DIRECTION IS MADE, THIS PROXY WILL BE VOTED
FOR PROPOSALS 1, 2, 3 AND 4.


   Detach above card, sign, date and mail in postage-paid envelope provided.
   36
                                   ALTEON INC


This proxy must be signed exactly as the name appears hereon. When shares are
held by joint tenants, both should sign. If the signer is a corporation, please
sign full corporate name by duly authorized officer, giving full title as such.
If a partnership, please sign in partnership name by authorized person.

                               PLEASE ACT PROMPTLY
                     SIGN, DATE & MAIL YOUR PROXY CARD TODAY