SECURITIES EXCHANGE COMMISSION
Washington, DC 20549
Under the Securities Exchange Act of 1934
(Amendment No.)
EPIX Pharmaceuticals, Inc.
(Name of Issuer)
Common Stock
(Title of Class of Securities)
26881Q309
(CUSIP NUMBER)
May 31, 2009
Date of Event Which Requires Filing of this Statement
Check the appropriate box to designate the rule
pursuant to which this Schedule is filed
[X] Rule 13d-1(b)
[ ] Rule 13d-1(c)
[ ] Rule 13d-1(d)
1) Name of Reporting Person: UniCredit S.p.A.
IRS Identification 000000000
No. of Above
2) Check the Appropriate Box (a)
of A Member of Group
(See Instructions) (b)
3) SEC Use Only
4) Citizenship of Place of
Organization Italy
Number of (5)Sole Voting
Shares Power 0
Beneficially Owned [See Item 4 below.]
by Each Reporting
Person With (6)Shared Voting
Power 0
[See Item 4 below.]
(7)Sole Disposi-
tive Power 0
[See Item 4 below.]
(8)Shared Disposi-
tive Power 0
[See Item 4 below.]
9) Aggregate Amount Beneficially 0
Owned by Each [See Item 4 below.]
Reporting Person
10) Check if the aggregate Amount in Row (9) Exclude Certain Shares (See
Instructions)
11) Percent of Class Represented
By Amount in Row 9. 0%
[See Item 4 below.]
12) Type of Reporting
Person (See Instructions) HC
1) Name of Reporting Person: Pioneer Global Asset Management S.p.A. (PGAM)
IRS Identification 000000000
No. of Above
2) Check the Appropriate Box (a)
of A Member of Group
(See Instructions) (b)
3) SEC Use Only
4) Citizenship of Place of
Organization Italy
Number of (5)Sole Voting
Shares Power 0
Beneficially Owned [See Item 4 below.]
by Each Reporting
Person With (6)Shared Voting
Power 11,187,000
[See Item 4 below.]
(7)Sole Disposi-
tive Power 0
[See Item 4 below.]
(8)Shared Disposi-
tive Power 11,187,000
[See Item 4 below.]
9) Aggregate Amount Beneficially 11,187,000
Owned by Each [See Item 4 below.]
Reporting Person
10) Check if the aggregate Amount in Row (9) Exclude Certain Shares (See
Instructions)
11) Percent of Class Represented
By Amount in Row 9. 14.96%
[See Item 4 below.]
12) Type of Reporting
Person (See Instructions) HC
1) Name of Reporting Person: Pioneer Investment Management, Inc. (PIM)
IRS Identification 13-1961193
No. of Above
2) Check the Appropriate Box (a)
of A Member of Group
(See Instructions) (b)
3) SEC Use Only
4) Citizenship of Place of
Organization Delaware
Number of (5)Sole Voting
Shares Power 0
Beneficially Owned [See Item 4 below.]
by Each Reporting
Person With (6)Shared Voting
Power 11,153,100
[See Item 4 below.]
(7)Sole Disposi-
tive Power 0
[See Item 4 below.]
(8)Shared Disposi-
tive Power 11,153,100
[See Item 4 below.]
9) Aggregate Amount Beneficially 11,153,100
Owned by Each [See Item 4 below.]
Reporting Person
10) Check if the aggregate Amount in Row (9) Exclude Certain Shares (See
Instructions)
11) Percent of Class Represented
By Amount in Row 9. 14.92%
[See Item 4 below.]
12) Type of Reporting
Person (See Instructions) IA
1) Name of Reporting Person: Pioneer Institutional Asset Management, Inc.
(PIAM)
IRS Identification 43-2095408
No. of Above
2) Check the Appropriate Box (a)
of A Member of Group
(See Instructions) (b)
3) SEC Use Only
4) Citizenship of Place of
Organization Delaware
Number of (5)Sole Voting
Shares Power 0
Beneficially Owned [See Item 4 below.]
by Each Reporting
Person With (6)Shared Voting
Power 33,900
[See Item 4 below.]
(7)Sole Disposi-
tive Power 0
[See Item 4 below.]
(8)Shared Disposi-
tive Power 33,900
[See Item 4 below.]
9) Aggregate Amount Beneficially 33,900
Owned by Each [See Item 4 below.]
Reporting Person
10) Check if the aggregate Amount in Row (9) Exclude Certain Shares (See
Instructions)
11) Percent of Class Represented
By Amount in Row 9. 0.04%
[See Item 4 below.]
12) Type of Reporting
Person (See Instructions) IA
Item 1(a) Name of Issuer.
EPIX Pharmaceuticals, Inc.
Item 1(b) Address of Issuer's Principal Executive Offices:
4 Maguire Road
Lexington, MA 02421
United States
Item 2(a) Name of Person Filing:
UniCredit S.p.A.;
PGAM; PIM; and
PIAM
Item 2(b) Address of Principal Business Office:
The principal business office for UniCredit S.p.A is:
Piazza Cordusio 2
20123 Milan, Italy
The principal business office for PGAM is:
Galleria San Carlo 6
Milan, Italy
The principal business office for PIM is:
60 State Street
Boston, MA 02109
The principal business office for PIAM is:
60 State Street
Boston, MA 02109
Item 2(c) Citizenship:
UniCredit S.p.A and PGAM are organized under the laws of Italy.
PIM and PIAM are a corporations organized under the laws of the
State of Delaware.
Item 2(d) Title of Class of Securities:
Common Stock
Item 2(e) Cusip Number:
26881Q309
Item 3 The person filing this statement pursuant to Rule 13d-1(b)
or 13d-2(b) is:
UniCredit S.p.A is a parent holding company or control
person in accordance with Section 240.13d-1(b)(1)(ii)(G).
PGAM is a parent holding company or control person in
accordance with Section 240.13d-1(b)(1)(ii)(G).
PIM is an investment adviser in accordance with Section
240.13d-1(b)(1)(ii)(E).
PIAM is an investment adviser in accordance with Section
240.13d-1(b)(1)(ii)(E).
Item 4. Ownership.
(a) Amount Beneficially Owned: 11,187,000**
(b) Percent of Class: 14.96%
(c) Number of shares as to which such person has
(i) sole power to vote or to direct the vote 0
(ii) shared power to vote or to direct vote 11,187,000**
(iii) sole power to dispose or to direct disposition of 0
(iv) shared power to dispose or to direct disposition 11,187,000**
**Shares reported on this Schedule 13G (the Shares) are owned by Funds
(investment companies registered under the Investment Company Act of 1940 and
unregistered entities) advised by PIM and PIAM. In its role as investment
manager or adviser to the Funds, PIM and PIAM possess investment and/or voting
control over the Shares.
PIM and PIAM are direct subsidiaries of PGAM and wholly-owned indirect
subsidiaries of UniCredit S.p.A. PGAM is a limited liability company and the
holding company incorporating all of the UniCredit S.p.A asset management
business which are, as of the date of this filing, PGAMs subsidiaries.
UniCredit S.p.A and PGAM are listed as reporting persons on this Schedule 13G
due to their respective indirect and direct controlling relationship with PIM
and PIAM. UniCredit S.p.A, PGAM, PIM and PIAM disclaim beneficial ownership of
the Shares except to the extent of their respective pecuniary interests therein,
if any. The filing of this Schedule 13G shall not be construed as an admission
that the Reporting Persons are the beneficial owners of the Shares for any other
purposes than Section 13(d) of the Securities Exchange Act of 1934.
Item 5. Ownership of Five Percent or Less of a Class.
If this statement is being filed to report the fact that as of the date Hereof
the reporting person has ceased to be the beneficial owner of more than five
percent of the class of securities, check here:
Item 6. Ownership of More than Five Percent on Behalf of Another Person.
Various persons have the right to receive or the power to direct the receipt
of dividends from, or the proceeds from the sale of, the Common Stock of
EPIX Pharmaceuticals, Inc. The Interest of one person, Pioneer High Yield Fund,
in the Common Stock of EPIX Pharmaceuticals, Inc., amounted to 10,453,065
shares or 13.98% of the total outstanding Common Stock at May 31, 2009.
Item 7. Identification and Classification of the Subsidiary Which Acquired
the Security Being Reported On By the Parent Holding Company.
See Item 4.
Item 8. Identification and Classification of Members of the Group.
Inapplicable.
Item 9. Notice of Dissolution of the Group.
Inapplicable.
Item 10. Certification.
By signing below I certify that, to the best of my knowledge and
belief, the securities referred to above were acquired and are held in the
ordinary course of business and were not acquired and are not held for the
purpose of or with the effect of changing or influencing the control of the
issuer of the securities and were not acquired and are not held in connection
with or as a participant in any transaction having that purpose or effect.
After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.
Date: June 5, 2009
Pioneer Global Asset Management S.p.A
By: /s/ Dario Frigerio
Name: Dario Frigerio
Title: CEO; Head of Asset Management Division
UniCredit S.p.A
By: /s/ Paolo Fiorentino
Name: Paolo Fiorentino
Title: Deputy CEO; Head of Global Banking Services Division
Pioneer Investment Management, Inc.
By: /s/ Teri W. Anderholm
Name: Teri W. Anderholm
Title: Chief Compliance Officer
Pioneer Institutional Asset Management, Inc.
By: /s/ Gerald H. Stanney, Jr.
Name: Gerald H. Stanney, Jr.
Title: Chief Compliance Officer
EXHIBIT
JOINT FILING AGREEMENT
In accordance with Rule 13d-1(k)(1) promulgated under the Securities Exchange
Act of 1934, the undersigned agree to the joint filing of a Statement on
Schedule 13G (including any and all amendments thereto) with respect to the
Common Stock of EPIX Pharmaceuticals, Inc. and further agree to the filing of
this agreement as an Exhibit thereto. Each party to this Agreement expressly
authorizes each other party to this Agreement to file on its behalf any and all
amendments to such Statement on Schedule 13G.
Date: June 5, 2009
Pioneer Global Asset Management S.p.A
By: /s/ Dario Frigerio
Name: Dario Frigerio
Title: CEO; Head of Asset Management Division
UniCredit S.p.A
By: /s/ Paolo Fiorentino
Name: Paolo Fiorentino
Title: Deputy CEO; Head of Global Banking Services Division
Pioneer Investment Management, Inc.
By: /s/ Teri W. Anderholm
Name: Teri W. Anderholm
Title: Chief Compliance Officer
Pioneer Institutional Asset Management, Inc.
By: /s/ Gerald H. Stanney, Jr.
Name: Gerald H. Stanney, Jr.
Title: Chief Compliance Officer