FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person * Mahatme Sandesh   2. Issuer Name and Ticker or Trading Symbol Sarepta Therapeutics, Inc. [SRPT] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner __X__ Officer (give title below) _____ Other (specify below) EVP, CFO & CBO (Last) (First) (Middle) 215 FIRST STREET, SUITE 415 3. Date of Earliest Transaction (Month/Day/Year) 01/30/2019 (Street) CAMBRIDGE, MA 02142 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 01/30/2019   M(1)   5,469 A $ 13.71 14,118 D   Common Stock 01/30/2019   M(1)   1,128 A $ 13.71 15,246 D   Common Stock 01/30/2019   M(1)   17,860 A $ 13.9 33,106 D   Common Stock 01/30/2019   M(1)   19,345 A $ 23.85 52,451 D   Common Stock 01/30/2019   S(1)   43,802 D $ 130 8,649 D   Common Stock 01/31/2019   M(1)   21,198 A $ 23.85 29,847 D   Common Stock 01/31/2019   S(1)   21,198 D $ 130.72 8,649 D   Common Stock               12,012 I By trust

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Stock Option (right to buy)

$ 13.71

01/30/2019

M(1)

5,469

02/28/2017

02/28/2026

Common Stock

5,469

$ 0

7,404

D

Stock Option (right to buy)

$ 13.71

01/30/2019

M(1)

1,128

02/28/2017

02/28/2026

Common Stock

1,128

$ 0

6,771

D

Stock Option (right to buy)

$ 13.9

01/30/2019

M(1)

17,860

02/27/2016

02/27/2025

Common Stock

17,860

$ 0

0

D

Stock Option (right to buy)

$ 23.85

01/30/2019

M(1)

19,345

11/05/2013

11/05/2022

Common Stock

19,345

$ 0

96,664

D

Stock Option (right to buy)

$ 23.85

01/31/2019

M(1)

21,198

11/05/2013

11/05/2022

Common Stock

21,198

$ 0

75,466

D

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Mahatme Sandesh 215 FIRST STREET, SUITE 415 CAMBRIDGE, MA 02142			EVP, CFO & CBO

Signatures

/s/ David Tyronne Howton, as attorney-in-fact for Sandesh Mahatme		02/01/2019
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	This transaction was effected pursuant to a Rule 10b5-1 Plan. Accordingly, the reporting person had no discretion with regards to the timing of the transaction.

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