Ownership Submission
FORM 5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Form 3 Holdings Reported
Form 4 Transactions Reported
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

ANNUAL STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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1. Name and Address of Reporting Person *
DRAKULIC BUDIMIR
 2. Issuer Name and Ticker or Trading Symbol
SIGNALIFE, INC. [sgn] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Chief Technology Officer
(Last)
(First)
(Middle)

4705 LAUREL CANYON BLVD, SUITE 203		 3. Statement for Issuer's Fiscal Year Ended (Month/Day/Year)
12/31/2005
(Street)


STUDIO CITY, CA 91607		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Reporting
(check applicable line)

_X_ Form Filed by One Reporting Person
___ Form Filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned at end of Issuer's Fiscal Year
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Amount (A) or (D) Price
Common stock (2)             600,000 (1) I By B World Technologies (3)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number. SEC 2270 (9-02)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned at End of Issuer's Fiscal Year
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
(A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Option to purchase $ 0.95     3     06/10/2003 03/28/2008 Common stock
46,875
  46,875 (1)
D
 
Option to purchase $ 0.95     3     09/10/2003 03/28/2008 Common stock
46,875
  46,875 (1)
D
 
Option to purchase $ 0.95     3     12/10/2003 03/28/2008 Common stock
46,875
  46,875 (1)
D
 
Option to purchase $ 0.95     3     03/10/2004 03/28/2008 Common stock
46,875
  46,875 (1)
D
 
Option to purchase $ 0.95     3     06/10/2004 03/28/2008 Common stock
46,875
  46,875 (1)
D
 
Option to purchase $ 0.95     3     09/10/2004 03/29/2008 Common stock
46,875
  46,875 (1)
D
 
Option to purchase $ 0.95     3     12/10/2004 03/28/2008 Common stock
46,875
  46,875 (1)
D
 
Option to purchase $ 0.95     3     03/10/2005 03/28/2008 Common stock
46,875
  46,875 (1)
D
 
Option to purchase $ 0.95     3     06/10/2005 03/28/2008 Common stock
46,875
  46,875 (1)
D
 
Option to purchase $ 0.95     3     09/10/2005 03/28/2008 Common stock
46,875
  46,875 (1)
D
 
Option to purchase $ 0.95     3     12/10/2005 03/28/2008 Common stock
46,875
  46,875 (1)
D
 
Option to purchase $ 0.95     3     03/10/2006 03/28/2008 Common stock
46,875
  46,875 (1)
D
 
Option to purchase $ 0.95     3     06/10/2006 03/28/2008 Common stock
46,875
  46,875 (1)
D
 
Option to purchase $ 0.95     3     09/10/2006 03/28/2008 Common stock
46,875
  46,875 (1)
D
 
Option to purchase $ 0.95     3     12/10/2006 03/28/2008 Common stock
46,875
  46,875 (1)
D
 
Option to purchase $ 0.95     3     03/10/2007 03/28/2008 Common stock
46,875
  46,875
D
 

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
DRAKULIC BUDIMIR
4705 LAUREL CANYON BLVD, SUITE 203
STUDIO CITY, CA 91607		       Chief Technology Officer  

Signatures

John Woodbury, as agent-in-fact for reporting owner 02/14/2006
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Holdings as of June 3, 2005, when original obligation to file form 3 arose.
(2) Restricted stock within meaning of IRC Section 83, subject to forfeiture to the extent not vested based upon continued employment. Shares vest quarterly in tranches of 30,000 shares per quarter over 5 year period commencing January 15, 2003.
(3) Corporation owned and controlled by reporting owner.

Note: File three copies of this Form, one of which must be manually signed. If space provided is insufficient, see Instruction 6 for procedure.

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