SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
FORM 6-K
REPORT OF FOREIGN PRIVATE ISSUER
PURSUANT TO RULE 13a - 16 OR 15d - 16 OF
THE SECURITIES EXCHANGE ACT OF 1934
For the month of April, 2007
SkyePharma PLC
SkyePharma PLC, 105 Piccadilly, London W1J 7NJ England
Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40F.
Form 20-F X Form 40-F
Indicate by check mark whether the registrant by furnishing the information contained in this Form is also thereby furnishing the information to the Commission pursuant to Rule 12g3-2(b) under the Securities Exchange Act of 1934.
Yes No X
If "Yes" is marked, indicate below the file number assigned to the registrant in connection with Rule 12g3-2(b): 82- _______
3 APRIL 2007 SkyePharma PLC - Annual Information Update In accordance with the requirements of Prospectus Rule 5.2, the following summarises the information and documents published, or made available to the public, by SkyePharma between 2 May 2005 and 2 May 2006 The information referred to in this update was up to date at the time it was published but some information may now be out of date. SkyePharma also confirms that it will issue a further Annual Information Update, within the 20 business days following publication of its annual results, which will cover the 12-month period immediately preceding such announcement. 1. Announcements via RNS The following UK regulatory announcements have been made via RNS a Regulatory Information Service and can be obtained from the London Stock Exchange website at www.londonstockexchange.com or the Company's website at www.skyepharma.com Date Announcement 6 May 2005 Additional Listing 9 May 2005 Triglide Approval 23 May 2005 Notification of Shares 24 May 2005 Notification of Shares 31 May 2005 Signed Agreement 1 Jun 2005 Share Purchase Plan 2 Jun 2005 Directors Share Purchase 3 Jun 2005 Director Shareholding 3 Jun 2005 Director Shareholding 6 Jun 2005 Re Convertible Bonds 20 Jun 2005 Approval in Germany 21 Jun 2005 Notification of Shares 28 Jun 2005 Paxil CRTM Returns to US 28 Jun 2005 First Filing for Pulmicort 1 Jul 2005 Share Purchase Plan 18 Jul 2005 US Launch of Triglide 18 Jul 2005 AGM Statement 20 Jul 2005 Notification of Shares 2 Aug 2005 Share Purchase Plan 3 Aug 2005 Notification of Shares 3 Aug 2005 2004 IFRS Figures 31 Aug 2005 Notification of Shares 2 Sep 2005 Results Date & Flutiform Update 7 Sep 2005 Launch of Foradil 8 Sep 2005 Notice of Interims 28 Sep 2005 Rights Issue 28 Sep 2005 Interim Results 30 Sep 2005 Notification of Interests 30 Sep 2005 Notification of Shares 3 Oct 2005 Director/PDMR Shareholding 3 Oct 2005 Holding(s) in Company 5 Oct 2005 Notification of Shares 5 Oct 2005 R&D Day Update 6 Oct 2005 Notification of Shares 6 Oct 2005 Notification of Shares 12 Oct 2005 Filing of Prospectus 17 Oct 2005 Notification of Shares 18 Oct 2005 Notification of Shares 18 Oct 2005 Notification of Shares - Amend 19 Oct 2005 Notification of Shares 21 Oct 2005 Notification of Shares 24 Oct 2005 Notification of Shares 25 Oct 2005 Notification of Shares 1 Nov 2005 Japanese Marketing Agreement 1 Nov 2005 Notification of Shares 3 Nov 2005 Rights Issue 3 Nov 2005 Placement of Rights Issue Rump 3 Nov 2005 Director/PDMR Shareholding 7 Nov 2005 Notification of Shares 10 Nov 2005 Notification of Shares 14 Nov 2005 Strategic Review 14 Nov 2005 Rule 2.10 Announcement 17 Nov 2005 Rule 2.10 Announcement 18 Nov 2005 Rule 2.10 Announcement 30 Nov 2005 Notification of Shares 2 Dec 2005 Holding(s) in Company 2 Dec 2005 Notice of Major Interests 5 Dec 2005 Notification of Shares 8 Dec 2005 Strategic Review Update 13 Dec 2005 Notification of Shares 28 Dec 2005 Share Purchase Plan 11 Jan 2006 Strategic Review 12 Jan 2006 Postponement of R&D Days 13 Jan 2006 Notice of Major Interest 16 Jan 2006 Notice of Major Interest 20 Jan 2006 Resignation of Chairman 20 Jan 2006 Responds to Call for EGM 23 Jan 2006 Holding(s) in Company 26 Jan 2006 Holding(s) in Company 30 Jan 2006 Further re call for EGM 2 Feb 2006 Appointment of New Chairman 3 Feb 2006 Director/PDMR Shareholding 3 Feb 2006 Director/PDMR Shareholding 3 Feb 2006 Director Shareholding 3 Feb 2006 Notification of Shares 6 Feb 2006 Board Appointment 6 Feb 2006 Notification of Shares 6 Feb 2006 Notification of Shares 7 Feb 2006 Response to NAV Syndicate 7 Feb 2006 Notification of Shares 8 Feb 2006 Notification of Shares 9 Feb 2006 Further re Employment Terms 9 Feb 2006 Notification of Shares 9 Feb 2006 Notification of Shares 13 Feb 2006 Former Chairman Retires 13 Feb 2006 Notification of Shares 13 Feb 2006 Notification of Shares 14 Feb 2006 Notification of Shares 15 Feb 2006 Director/PDMR Shareholding 16 Feb 2006 EGM Circular 23 Feb 2006 Notification of Shares 23 Feb 2006 Notification of Shares 27 Feb 2006 EGM Nominee Voting 1 Mar 2006 Share Purchase Plan 2 Mar 2006 Response to NAV 3 Mar 2006 Full Response to NAV 3 Mar 2006 Notification of Shares 3 Mar 2006 Financial Position 6 Mar 2006 Holding(s) in Company 9 Mar 2006 Result of EGM 14 Mar 2006 Agreement over Non-Executives 15 Mar 2006 Notification of Shares 17 Mar 2006 Notification of Shares 27 Mar 2006 Notice of Results 3 Apr 2006 Share Purchase Plan 5 Apr 2006 Board Appointment 19 Apr 2006 Preliminary Results 21 Apr 2006 Propofol Update 24 Apr 2006 Holding(s) in Company 24 Apr 2006 Notification of Interests 24 Apr 2006 Directors Share Awards 26 Apr 2006 Notification of Interests 28 Apr 2006 European Approval of DepoDur 2 May 2006 Notification of Shares 2. Documents filed at Companies House All of the documents listed below were filed with the Registrar of Companies in England and Wales on or around the dates indicated. Copies of the documents filed with the Registrar of Companies can be obtained from Companies House (www.companieshouse.gov.uk) Date of Filing Brief Description of document(s) filed 16/05/2005 88(2)R Return Allotment of Shares 28/07/2005 AA Annual Accounts 30/07/2005 RES09 Resolutions 03/08/2005 288b Director Resigned 27/09/2005 288c Directors Particulars Changed 30/01/2006 363 Return made up to 31/12/05 22/02/2006 288b Director resigned 3. Documents published or sent to Shareholders or filed with the UK Listing Authority viewing facility at: Financial Services Authority The North Colonnade Canary Wharf London E14 5HS Date Document June 2005 Annual Report and Notice of Meeting October 2005 Interim Report October 2005 Rights Issue Prospectus February 2006 EGM Circular and Notice of Meeting Copies of the above documents can be obtained from the Company Secretary at: 105 Piccadilly London W1J 7NJ Name of contact and telephone number for queries: John Murphy Company Secretary SkyePharma PLC Tel: 020 7491 1777
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.
SkyePharma PLC
By: /s/ John Murphy
Name: John Murphy
Title:
Company Secretary
Date: April 04, 2007