Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
ENRIGHT PATRICK G
   2. Issuer Name and Ticker or Trading Symbol
Jazz Pharmaceuticals plc [JAZZ] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
C/O LONGITUDE CAPITAL PARTNERS, LLC, 800 EL CAMINO REAL, SUITE 220		 3. Date of Earliest Transaction (Month/Day/Year)
10/05/2015
(Street)

MENLO PARK, CA 94025		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Ordinary Shares 10/05/2015   S   2,102 D $ 132.255 (1) 262,594 I By Longitude Venture Partners, L.P. (2)
Ordinary Shares 10/05/2015   S   4,193 D $ 132.9392 (3) 258,401 I By Longitude Venture Partners, L.P. (2)
Ordinary Shares 10/05/2015   S   1,225 D $ 134.3172 (4) 257,176 I By Longitude Venture Partners, L.P. (2)
Ordinary Shares 10/05/2015   S   490 D $ 135.726 (5) 256,686 I By Longitude Venture Partners, L.P. (2)
Ordinary Shares 10/05/2015   S   1,695 D $ 136.6018 (6) 254,991 I By Longitude Venture Partners, L.P. (2)
Ordinary Shares 10/05/2015   S   99 D $ 137.81 254,892 I By Longitude Venture Partners, L.P. (2)
Ordinary Shares 10/05/2015   S   43 D $ 132.256 (7) 5,261 I By Longitude Capital Associates, L.P. (2)
Ordinary Shares 10/05/2015   S   83 D $ 132.939 (8) 5,178 I By Longitude Capital Associates, L.P. (2)
Ordinary Shares 10/05/2015   S   25 D $ 134.3172 (9) 5,153 I By Longitude Capital Associates, L.P. (2)
Ordinary Shares 10/05/2015   S   10 D $ 135.726 (10) 5,143 I By Longitude Capital Associates, L.P. (2)
Ordinary Shares 10/05/2015   S   34 D $ 136.6041 (11) 5,109 I By Longitude Capital Associates, L.P. (2)
Ordinary Shares 10/05/2015   S   1 D $ 137.81 5,108 I By Longitude Capital Associates, L.P. (2)
Ordinary Shares               1,734 D  

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
ENRIGHT PATRICK G
C/O LONGITUDE CAPITAL PARTNERS, LLC
800 EL CAMINO REAL, SUITE 220
MENLO PARK, CA 94025		   X      

Signatures

 /s/ Patrick G. Enright   10/07/2015
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Reflects sales of ordinary shares executed in multiple transactions at prices ranging from $131.71 to $132.69. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.
(2) The Reporting Person is a managing member of Longitude Capital Partners, LLC, the general partner of each of Longitude Venture Partners, L.P. and Longitude Capital Associates, L.P. The Reporting Person disclaims beneficial ownership of the securities of the Issuer held by Longitude Venture Partners, L.P. and Longitude Capital Associates, L.P. except to the extent of his pecuniary interest therein.
(3) Reflects sales of ordinary shares executed in multiple transactions at prices ranging from $132.73 to $133.36. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.
(4) Reflects sales of ordinary shares executed in multiple transactions at prices ranging from $133.85 to $134.71. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.
(5) Reflects sales of ordinary shares executed in multiple transactions at prices ranging from $135.10 to $136.05. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.
(6) Reflects sales of ordinary shares executed in multiple transactions at prices ranging from $136.29 to $136.80. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.
(7) Reflects sales of ordinary shares executed in multiple transactions at prices ranging from $131.71 to $132.69. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.
(8) Reflects sales of ordinary shares executed in multiple transactions at prices ranging from $132.73 to $133.36. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.
(9) Reflects sales of ordinary shares executed in multiple transactions at prices ranging from $133.85 to $134.71. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.
(10) Reflects sales of ordinary shares executed in multiple transactions at prices ranging from $135.10 to $136.05. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.
(11) Reflects sales of ordinary shares executed in multiple transactions at prices ranging from $136.29 to $136.80. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.
 
Remarks:
All of the sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

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