Edgar Filing: QIAGEN NV

2014.3.31 6-K

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

__________________________________

FORM 6-K

__________________________________

REPORT OF FOREIGN PRIVATE ISSUER

PURSUANT TO RULE 13a-16 OR 15d-16 OF

THE SECURITIES EXCHANGE ACT OF 1934

For the quarterly period ended March 31, 2014

Commission File Number 0-28564

__________________________________

QIAGEN N.V.

__________________________________

Spoorstraat 50

5911 KJ Venlo

The Netherlands

__________________________________

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F:

Form 20-F x Form 40-F o

Indicate by check mark whether the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1): o

Indicate by check mark whether the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7): o

Indicate by check mark whether the registrant by furnishing the information contained in this Form is also thereby furnishing the information to the Commission pursuant to Rule 12g3-2(b) under the Securities Exchange Act of 1934.

Yes o No x

If “Yes” is marked, indicate below the file number assigned to the registrant in connection with Rule 12g3-2(b): 82- .

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QIAGEN N.V.

Form 6-K

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Item		Page
Other Information		3
Signatures		4
Exhibit Index		5

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OTHER INFORMATION

For the three-month period ended March 31, 2014, QIAGEN N.V. prepared its quarterly report under United States generally accepted accounting principles (U.S. GAAP). This quarterly report is furnished herewith as Exhibit 99.1 and incorporated by reference herein.

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SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this Report to be signed on its behalf by the undersigned, thereunto duly authorized.



QIAGEN N.V.

BY:	/S/ ROLAND SACKERS
	Roland Sackers
	Chief Financial Officer

Date:	May 7, 2014

EXHIBIT INDEX



Exhibit No.		Exhibit

99.1		U.S. GAAP Quarterly Report for the Period Ended March 31, 2014

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Exhibit 99.1

QIAGEN N.V. AND SUBSIDIARIES

U.S. GAAP QUARTERLY REPORT FOR THE PERIOD ENDED MARCH 31, 2014

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Financial Information

Condensed Consolidated Financial Statements

Condensed Consolidated Balance Sheets as of March 31, 2014 (unaudited) and December 31, 2013	2

Condensed Consolidated Statements of Income (unaudited) for the three months ended March 31, 2014 and 2013	4

Condensed Consolidated Statements of Comprehensive Income (Loss) (unaudited) for the three months ended March 31, 2014 and 2013	5

Condensed Consolidated Statements of Changes in Equity (unaudited) for the three months ended March 31, 2014 and 2013	6

Condensed Consolidated Statements of Cash Flows (unaudited) for the three months ended March 31, 2014 and 2013	7

Notes to Condensed Consolidated Financial Statements (unaudited)	8

Operating and Financial Review and Prospects	22

Quantitative and Qualitative Disclosures About Market Risk	28

Recent Authoritative Pronouncements	29

Application of Critical Accounting Policies, Judgments and Estimates	29

Off-Balance Sheet Arrangements	29

Contractual Obligations	29

Legal Proceedings	29

Risk Factors	29

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QIAGEN N.V. AND SUBSIDIARIES

CONDENSED CONSOLIDATED BALANCE SHEETS

(in thousands)



	Note	March 31, 2014		December 31, 2013
		(unaudited)
Assets
Current assets:
Cash and cash equivalents		$	564,272	$	330,303
Short-term investments		113,701		49,923
Accounts receivable, net of allowance for doubtful accounts of $10,817 and $10,683 in 2014 and 2013, respectively		244,828		259,710
Income taxes receivable		51,190		46,874
Inventories, net	(11)	133,412		128,097
Prepaid expenses and other current assets		73,063		66,290
Deferred income taxes		35,639		39,692
Total current assets		1,216,105		920,889
Long-term assets:
Property, plant and equipment, net		450,614		445,044
Goodwill	(6)	1,864,022		1,855,691
Intangible assets, net of accumulated amortization of $663,631and $630,136 in 2014 and 2013, respectively	(6)	761,411		790,405
Deferred income taxes		5,078		5,081
Other assets		189,282		71,282
Total long-term assets		3,270,407		3,167,503
Total assets		$	4,486,512	$	4,088,392

The accompanying notes are an integral part of these condensed consolidated financial statements.

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QIAGEN N.V. AND SUBSIDIARIES

CONDENSED CONSOLIDATED BALANCE SHEETS

(in thousands, except par value)



	Note	March 31, 2014			December 31, 2013
		(unaudited)
Liabilities and equity
Current liabilities:
Current portion of long-term debt	(9)	$	414		$	207
Accounts payable		40,930			50,869
Accrued and other liabilities (of which $1,396 and $6,943 due to related parties in 2014 and 2013, respectively)	(16)	217,847			245,236
Income taxes payable		51,769			38,131
Deferred income taxes		2,639			2,595
Total current liabilities		313,599			337,038
Long-term liabilities:
Long-term debt, net of current portion (of which $145,000 in 2014 and $445,000 in 2013 due to related parties)	(9) (16)	1,170,882			845,276
Deferred income taxes		133,973			143,760
Other liabilities		135,470			38,447
Total long-term liabilities		1,440,325			1,027,483
Commitments and contingencies	(14)
Equity:
Preference shares, 0.01 EUR par value, authorized—450,000 shares, no shares issued and outstanding		—			—
Financing preference shares, 0.01 EUR par value, authorized—40,000 shares, no shares issued and outstanding		—			—
Common Shares, 0.01 EUR par value, authorized—410,000 shares, issued—239,707 shares in 2014 and in 2013		2,812			2,812
Additional paid-in capital		1,792,745			1,777,894
Retained earnings		1,063,190			1,054,431
Accumulated other comprehensive income (loss)	(12)	7,628			(4,192		)
Less treasury shares at cost—6,587 and 5,817 shares in 2014 and in 2013, respectively		(142,691		)	(116,613		)
Equity attributable to the owners of QIAGEN N.V.		2,723,684			2,714,332
Noncontrolling interest		8,904			9,539
Total equity		2,732,588			2,723,871
Total liabilities and equity		$	4,486,512		$	4,088,392

The accompanying notes are an integral part of these condensed consolidated financial statements.

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QIAGEN N.V. AND SUBSIDIARIES

CONDENSED CONSOLIDATED STATEMENTS OF INCOME

(in thousands, except per share data)



	Three months ended
	March 31,
	2014			2013
	(unaudited)
Net sales	$	317,073		$	303,576
Cost of sales	106,955			103,563
Gross profit	210,118			200,013
Operating expenses:
Research and development	40,336			34,300
Sales and marketing	91,373			89,577
General and administrative, restructuring, integration and other	26,791			38,962
Acquisition-related intangible amortization	9,315			8,103
Total operating expenses	167,815			170,942
Income from operations	42,303			29,071
Other income (expense):
Interest income	1,010			858
Interest expense	(8,002		)	(7,665		)
Other (expense) income, net	(7,472		)	517
Total other expense, net	(14,464		)	(6,290		)
Income before income taxes	27,839			22,781
Income taxes	4,556			2,708
Net income	23,283			20,073
Net income attributable to noncontrolling interest	16			90
Net income attributable to the owners of QIAGEN N.V.	$	23,267		$	19,983
Basic earnings per common share attributable to the owners of QIAGEN N.V.	$	0.10		$	0.09
Diluted earnings per common share attributable to the owners of QIAGEN N.V.	$	0.10		$	0.08

Weighted-average shares outstanding
Basic	232,856			233,325
Diluted	242,946			241,450

The accompanying notes are an integral part of these condensed consolidated financial statements.

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QIAGEN N.V. AND SUBSIDIARIES

CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME (LOSS)

(in thousands)



	Three Months Ended
	March 31,
	2014			2013
	(unaudited)
Net income	$	23,283		$	20,073
Foreign currency translation adjustments, before tax	11,467			(23,423		)
Other comprehensive loss, before tax	11,467			(23,423		)
Income tax relating to components of other comprehensive loss	(37		)	(24		)
Total other comprehensive loss, after tax	11,430			(23,447		)
Comprehensive income (loss)	34,713			(3,374		)
Less: Comprehensive (loss) income attributable to noncontrolling interest	(374		)	124
Comprehensive income (loss) attributable to the owners of QIAGEN N.V.	$	35,087		$	(3,498	)

The accompanying notes are an integral part of these condensed consolidated financial statements.

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QIAGEN N.V. AND SUBSIDIARIES

CONDENSED CONSOLIDATED STATEMENTS OF CHANGES IN EQUITY

(in thousands)



		Common Shares			Additional Paid-In Capital			Retained Earnings			Accumulated Other Comprehensive Income			Treasury Shares					Equity Attributable to the Owners of QIAGEN N.V.			Non-controlling Interest			Total Equity
(unaudited)	Note	Shares	Amount		Additional Paid-In Capital			Retained Earnings			Accumulated Other Comprehensive Income			Shares		Amount			Equity Attributable to the Owners of QIAGEN N.V.			Non-controlling Interest			Total Equity
BALANCE AT DECEMBER 31, 2013		239,707	$	2,812	$	1,777,894		$	1,054,431		$	(4,192	)	(5,817	)	$	(116,613	)	$	2,714,332		$	9,539		$	2,723,871
Acquisition of Ipsogen S.A. shares from non-controlling interests	(3)	—	—		—			—			—			—		—			—			(261		)	(261		)
Net income		—	—		—			23,267			—			—		—			23,267			16			23,283
Proceeds from subscription receivables		—	—		409			—			—			—		—			409			—			409
Redemption of subscription receivables	(9)	—	—		(67,942		)	—			—			—		—			(67,942		)	—			(67,942		)
Issuance of Warrants	(12)	—	—		69,419			—			—			—		—			69,419			—			69,419
Translation adjustment, net	(12)	—	—		—			—			11,820			—		—			11,820			(390		)	11,430
Purchase of treasury shares	(12)	—	—		—			—			—			(1,872	)	(43,310		)	(43,310		)	—			(43,310		)
Issuance of common shares in connection with stock plan		—	—		—			(14,508		)	—			1,102		17,232			2,724			—			2,724
Share-based compensation	(15)	—	—		10,145			—			—			—		—			10,145			—			10,145
Excess tax benefit of employee stock plans		—	—		2,820			—			—			—		—			2,820			—			2,820
BALANCE AT MARCH 31, 2014		239,707	$	2,812	$	1,792,745		$	1,063,190		$	7,628		(6,587	)	$	(142,691	)	$	2,723,684		$	8,904		$	2,732,588

BALANCE AT DECEMBER 31, 2012		236,487	$	2,769	$	1,718,163		$	985,434		$	43,991		(1,943	)	$	(35,653	)	$	2,714,704		$	9,659		$	2,724,363
Acquisition of Ipsogen S.A. shares from non-controlling interests		—	—		—			—			—			—		—			—			(9		)	(9		)
Net income		—	—		—			19,983			—			—		—			19,983			90			20,073
Proceeds from subscription receivables		—	—		122			—			—			—		—			122			—			122
Unrealized gain, net on hedging contracts		—	—		—			—			—			—		—			—			—			—
Realized loss, net on hedging contracts		—	—		—			—			—			—		—			—			—			—
Translation adjustment, net		—	—		—			—			(23,481		)	—		—			(23,481		)	34			(23,447		)
Purchase of treasury shares		—	—		—			—			—			(3,012	)	(60,782		)	(60,782		)	—			(60,782		)
Issuance of common shares in connection with stock plan		2,497	32		17,085			—			—			—		—			17,117			—			17,117
Share-based compensation		—	—		8,597			—			—			—		—			8,597			—			8,597
Excess tax benefit of employee stock plans		—	—		4,755			—			—			—		—			4,755			—			4,755
BALANCE AT MARCH 31, 2013		238,984	$	2,801	$	1,748,722		$	1,005,417		$	20,510		(4,955	)	$	(96,435	)	$	2,681,015		$	9,774		$	2,690,789

The accompanying notes are an integral part of these condensed consolidated financial statements.

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QIAGEN N.V. AND SUBSIDIARIES

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

(in thousands)



		Three months ended
		March 31,
	Note	2014			2013
Cash flows from operating activities:		(unaudited)
Net income		$	23,283		$	20,073
Adjustments to reconcile net income to net cash provided by operating activities, net of effects of businesses acquired:
Depreciation and amortization		49,122			45,085
Non-cash impairment other assets		1,200			—
Share-based compensation expense	(15)	10,145			8,597
Excess tax benefits from share-based compensation		(2,820		)	(4,755		)
Deferred income taxes		(6,797		)	(10,602		)
Loss on early redemption of debt	(9)	4,560			—
Other		1,201			748
Net changes in operating assets and liabilities:
Accounts receivable		15,120			1,025
Inventories		(7,263		)	(2,871		)
Accounts payable		(10,209		)	(12,859		)
Accrued and other liabilities		(35,311		)	(3,457		)
Other		3,379			4,891
Net cash provided by operating activities		45,610			45,875
Cash flows from investing activities:
Purchases of property, plant and equipment		(17,344		)	(15,774		)
Proceeds from sale of equipment		—			39
Purchases of intangible assets		(1,887		)	(6,923		)
Purchases of investments		(5,245		)	(546		)
Cash paid for acquisitions, net of cash acquired		179			—
Purchases of short-term investments		(63,566		)	—
Net cash used in investing activities		(87,863		)	(23,204		)
Cash flows from financing activities:
Proceeds from issuance of cash convertible notes, net of issuance costs	(9)	722,700			—
Purchase of call option related to cash convertible notes	(9)	(105,170		)	—
Proceeds from issuance of warrants	(12)	69,419			—
Net proceeds from short-term debt		—			(209		)
Repayment of long-term debt	(9)	(371,895		)	(35		)
Principal payments on capital leases		(1,004		)	(923		)
Proceeds from subscription receivables		409			122
Excess tax benefits from share-based compensation		2,820			4,755
Proceeds from issuance of common shares		2,724			17,116
Purchase of treasury shares	(12)	(43,310		)	(60,782		)
Other financing activities		(261		)	(161		)
Net cash provided by (used in) financing activities		276,432			(40,117		)
Effect of exchange rate changes on cash and cash equivalents		(210		)	(3,834		)
Net increase (decrease) in cash and cash equivalents		233,969			(21,280		)
Cash and cash equivalents, beginning of period		330,303			394,037
Cash and cash equivalents, end of period		$	564,272		$	372,757

The accompanying notes are an integral part of these condensed consolidated financial statements.

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QIAGEN N.V. AND SUBSIDIARIES

NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

(unaudited)


1.	Corporate Information

QIAGEN N.V. is a public limited liability company ('naamloze vennootschap') under Dutch law with a registered office at Spoorstraat 50, Venlo, The Netherlands. QIAGEN N.V., a Netherlands holding company, and subsidiaries (QIAGEN, we, our or the Company) is a leading provider of innovative Sample and Assay Technologies. These technologies—consumable products such as sample and assay kits and automated instrumentation systems—empower customers to transform raw biological samples into valuable molecular information. We serve four major customer classes: Molecular Diagnostics laboratories; Applied Testing customers in fields such as forensics, veterinary diagnostics and food safety; Pharmaceutical research and development groups; and Academic researchers. We market our products in more than 100 countries.


2.	Basis of Presentation and Accounting Policies

Basis of Presentation

The condensed consolidated financial statements include the accounts of QIAGEN N.V., its wholly-owned subsidiaries, and any partially owned subsidiaries that the Company has the ability to control which are not considered variable interest entities. All significant intercompany accounts and transactions have been eliminated. All amounts are presented in U.S. dollars, unless otherwise indicated. Investments in companies where we exercise significant influence over the operations but do not have control, and where we are not the primary beneficiary, are accounted for using the equity method. All other investments are accounted for under the cost method. When there is a portion of equity in an acquired subsidiary not attributable, directly or indirectly, to the Company, we record the fair value of the noncontrolling interests at the acquisition date and classify the amounts attributable to noncontrolling interests separately in equity in the condensed consolidated financial statements. Any subsequent changes in the Company's ownership interest while the Company retains its controlling financial interest in its subsidiary are accounted for as equity transactions.

On April 29, 2013, we acquired Ingenuity Systems, Inc. (Ingenuity), located in Redwood City, California and on August 23, 2013 we acquired CLC bio (CLC), located in Aarhus, Denmark. Accordingly, as of the acquisition dates, all of the assets acquired and liabilities assumed were recorded at their respective fair values and our consolidated results of operations include Ingenuity’s and CLC's operating results beginning April 29, 2013 and August 22, 2013, respectively.

The accompanying unaudited condensed consolidated financial statements have been prepared in accordance with U.S. generally accepted accounting principles (U.S. GAAP) for interim financial information and generally in accordance with the instructions to Form 10-Q and Article 10 of Regulation S-X. Certain information and footnote disclosures normally included in financial statements prepared in accordance with U.S. GAAP have been condensed or omitted pursuant to the Securities and Exchange Commission (SEC) rules and regulations. In the opinion of management, all adjustments (which include only normal recurring adjustments) necessary for a fair presentation have been included.

We operate as one operating segment in accordance with the Financial Accounting Standards Board (FASB) Accounting Standards Codification (ASC) Topic 280, Segment Reporting. We have a common basis of organization, our products and services are offered globally and have consistent product margins. Our chief operating decision maker (CODM) makes decisions based on the Company as a whole. Accordingly, we operate and make decisions as one reporting unit.

The results of operations for an interim period are not necessarily indicative of results that may be expected for any other interim period or for the full year. These unaudited condensed consolidated financial statements should be read in conjunction with the audited consolidated financial statements and notes thereto included in the Company's Annual Report on Form 20-F for the year ended December 31, 2013.

Summary of Significant Accounting Policies

The interim condensed consolidated financial statements were prepared based on the same accounting policies as those applied and described in the consolidated financial statements as of December 31, 2013 including the adoption of new standards and interpretations as of January 1, 2014.

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Adoption of New Accounting Standards

In February 2013, the FASB issued Accounting Standards Update No. 2013-04, "Liabilities (Topic 405) ─Obligations Resulting from Joint and Several Liability Arrangements for Which the Total Amount of the Obligation Is Fixed at the Reporting Date" (ASU 2013-04). The amendments in this update provide guidance for the recognition, measurement, and disclosure of obligations resulting from joint and several liability arrangements for which the total amount of the obligation within the scope of this update is fixed at the reporting date, except for obligations addressed within existing guidance in U.S. GAAP. The guidance requires an entity to measure those obligations as the sum of the amount the reporting entity agreed to pay on the basis of its arrangement among its co-obligors and any additional amount the reporting entity expects to pay on behalf of its co-obligors. The guidance in this update also requires an entity to disclose the nature and amount of the obligation as well as other information about those obligations. The requirements of ASU 2013-04 became effective for us on January 1, 2014 and did not have any material impact on our consolidated financial statements.

In March 2013, the FASB issued Accounting Standards Update No. 2013-05, "Foreign Currency Matters (Topic 830): Parent's Accounting for the Cumulative Translation Adjustment upon Derecognition of Certain Subsidiaries or Groups of Assets within a Foreign Entity or of an Investment in a Foreign Entity" (ASU 2013-05). The amendments in ASU 2013-05 provide guidance on releasing Cumulative Translation Adjustments (CTA) when a reporting entity (parent) ceases to have a controlling financial interest in a subsidiary or group of assets that is a nonprofit activity or a business within a foreign entity. In addition, these amendments provide guidance on the release of CTA in partial sales of equity method investments and in step acquisitions. For public entities, the amendments are effective on a prospective basis for fiscal years and interim reporting periods within those years, beginning after December 15, 2013. The amendments should be applied prospectively to derecognition events occurring after the effective date. Prior periods should not be adjusted and early adoption is permitted. ASU 2013-05 became effective for us in the period beginning January 1, 2014 and its adoption did not have an effect on our financial position, results of operations or cash flows.

In July 2013, the FASB issued Accounting Standards Update No. 2013-11 (ASU 2013-11), "Presentation of an Unrecognized Tax Benefit When a Net Operating Loss Carryforward, a Similar Tax Loss, or a Tax Credit Carryforward Exists" (a consensus of the FASB Emerging Issues Task Force), which requires an entity to present an unrecognized tax benefit as a reduction of a deferred tax asset for a net operating loss (NOL) carryforward, or similar tax loss or tax credit carryforward, rather than as a liability when (1) the uncertain tax position would reduce the NOL or other carryforward under the tax law of the applicable jurisdiction and (2) the entity intends to use the deferred tax asset for that purpose. The ASU does not require new disclosures. It is effective prospectively for fiscal years, and interim periods within those years, beginning after December 15, 2013. ASU 2013-11 became effective for us in the period beginning January 1, 2014 and its adoption did not have a significant effect on our financial position, results of operations or cash flows.


3.	Acquisitions

Acquisitions have been accounted for as business combinations, and the acquired companies’ results have been included in the accompanying condensed consolidated statements of income from their respective dates of acquisition. Our acquisitions have historically been made at prices above the fair value of the acquired net assets, resulting in goodwill, due to expectations of synergies of combining the businesses. These synergies include use of our existing infrastructure, such as sales force, shared service centers, distribution channels and customer relations, to expand sales of the acquired businesses’ products; use of the infrastructure of the acquired businesses to cost-effectively expand sales of our products; and elimination of duplicative facilities, functions and staffing.

2013 Acquisition

On April 29, 2013, we acquired 100% of the outstanding common shares of Ingenuity Systems, Inc. (Ingenuity), a leading provider of software solutions that efficiently and accurately analyze and interpret the biological meaning of genomic data. The cash consideration totaled $106.9 million of which $10.0 million was retained in an escrow account as of March 31, 2014 to cover any claims for breach of any representations, warranties or indemnities. The acquisition of Ingenuity did not have a material impact to net sales, net income or earnings per share and therefore no proforma information has been provided herein.

The final purchase price allocation for Ingenuity did not differ from the preliminary estimates other than the recognition of approximately $0.1 million of purchase consideration, $3.0 million increase of long-term deferred tax asset, $4.1 million increase of long-term deferred tax liability and an additional $0.3 million increase of other opening balance sheet adjustments. The corresponding impact for these adjustments was an increase to goodwill of $0.7 million. These changes to arrive at the final purchase price allocation were not material to the consolidated financial statements. The final purchase price allocation for Ingenuity is as follows:

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(in thousands)	Ingenuity Systems acquisition
Purchase Price:
Cash consideration	$	106,932
	$	106,932

Allocation:
Cash and cash equivalents	$	4,449
Accounts receivable	2,018
Prepaid and other current assets	1,834
Current deferred tax asset	3,126
Fixed and other long-term assets	2,648
Long-term deferred tax asset	13,203
Accounts payable	(2,662		)
Accruals and other current liabilities	(14,558		)
Liabilities assumed	(557		)
Developed technology, licenses and know-how	37,903
Tradenames	3,359
In-process research and development	2,069
Customer relationships	1,023
Goodwill	69,479
Deferred tax liability on fair value of identifiable intangible assets acquired	(16,402		)
	$	106,932

The weighted-average amortization period for the intangible assets is 14.1 years. The goodwill acquired is not deductible for tax purposes.

Other Acquisitions

During 2011, we acquired a majority shareholding in QIAGEN Marseille S.A., formerly Ipsogen S.A. (Marseille), a publicly listed company founded and based in Marseille, France. During 2014, we acquired additional Marseille shares for a total of $0.3 million and held 90.21% of the Marseille shares as of March 31, 2014.


4.	Restructuring

Late in 2011, we began a project to enhance productivity by streamlining the organization and reallocating resources to strategic initiatives to help drive growth and innovation, strengthen our industry leadership position and improve longer-term profitability. This project aims to eliminate organizational layers and overlapping structures, actions that we expect will enhance our processes, speed and productivity. The last group of initiatives included actions to focus R&D activities on higher-growth areas in all customer classes, concentrate operations at fewer sites, and realign sales and regional marketing teams in the U.S. and Europe to better address customer needs in a more streamlined manner across the continuum from basic research to translational medicine and clinical diagnostics. Restructuring charges were recorded in 2013 as part of this transformational project. In the first quarter of 2013, we recorded pretax charges of $10.3 million in general, administrative, restructuring and other. The pretax charges consist of $2.3 million for personnel related costs, consulting costs of $7.6 million and $0.4 million of facility and other costs. Additionally, we recorded $1.7 million in cost of sales related primarily to personnel costs. No additional costs were incurred in the first quarter of 2014.

The following table summarizes the components of the restructuring costs. At March 31, 2014 and December 31, 2013, restructuring accruals of $3.1 million and $10.6 million, respectively, were included in accrued and other liabilities in the accompanying condensed consolidated balance sheets.

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(in thousands)	Personnel Related			Facility Related		Contract and Other Costs			Total
Balance at December 31, 2013	$	9,782		$	313	$	511		$	10,606
Payments	(5,974		)	—		(10		)	(5,984		)
Release of excess accrual	(1,576		)	—		—			(1,576		)
Foreign currency translation adjustment	12			—		—			12
Balance at March 31, 2014	$	2,244		$	313	$	501		$	3,058

The costs in the above table do not include consulting costs associated with third-party service providers that assisted with executing the restructuring. We accrued for consulting costs as the services were provided.


5.	Investments

We have made strategic investments in certain companies that are accounted for using the equity or cost method of accounting. The method of accounting for an investment depends on the level of influence. We monitor changes in circumstances that may require a reassessment of the level of influence. We periodically review the carrying value of these investments for impairment, considering factors such as the most recent stock transactions and book values from the recent financial statements. The fair value of cost and equity-method investments is estimated when there are identified events or changes in circumstances that may have an impact on the fair value of the investment.

As of March 31, 2014 and December 31, 2013, we had a total of cost-method investments in non-publicly traded companies with carrying amounts of $19.4 million and $15.4 million, respectively, which are included in other assets. The fair-value of these cost-method investments are not estimated unless there are identified events or changes in circumstances that may have a significant adverse effect on the fair value of the investment. For the three-month period ended March 31, 2014, we recorded an impairment of a cost method investment of $1.2 million in research and development expense.

FASB ASC Topic 810 requires a company to consolidate a variable interest entity if it is designated as the primary beneficiary of that entity even if the company does not control a majority of voting interests. A variable interest entity is generally defined as an entity with insufficient equity to finance its activities or where the owners of the entity lack the risk and rewards of ownership. We have a 50% interest in a joint venture company, PreAnalytiX GmbH (PreAnalytiX), for which we are not the primary beneficiary. Thus, the investment is accounted for under the equity method. PreAnalytiX was formed to develop, manufacture and market integrated systems for the collection, stabilization and purification of nucleic acids for molecular diagnostic testing. At present, our maximum exposure to loss as a result of our involvement with PreAnalytiX is limited to our share of losses from the equity method investment.

We also have 100% interests in two entities established for the purpose of issuing convertible debt which are not consolidated. These entities are discussed in Note 9.


6.	Intangible Assets

The following table sets forth the intangible assets by major asset class as of March 31, 2014 and December 31, 2013:



	March 31, 2014					December 31, 2013
(in thousands)	Gross Carrying Amount		Accumulated Amortization			Gross Carrying Amount		Accumulated Amortization
Amortized Intangible Assets:
Patent and license rights	$	327,737	$	(175,968	)	$	326,614	$	(168,637	)
Developed technology	697,205		(328,543		)	692,727		(310,842		)
Customer base and trademarks	390,618		(159,120		)	392,431		(150,657		)
	$	1,415,560	$	(663,631	)	$	1,411,772	$	(630,136	)
Unamortized Intangible Assets:
In-process research and development	$	9,482				$	8,769
Goodwill	1,864,022					1,855,691
	$	1,873,504				$	1,864,460

The estimated fair values of acquired in-process research and development projects which have not reached technological feasibility at the date of acquisition are capitalized and subsequently tested for impairment through completion of the development process, at which point the capitalized amounts are amortized over their estimated useful life. If a project is abandoned rather than completed, all

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capitalized amounts are written-off immediately. The amortization of the remaining in-process research and development is expected to begin during 2014 as the projects are completed.

The changes in intangibles assets in 2014 are summarized as follows:



(in thousands)	Intangibles			Goodwill
Balance at December 31, 2013	$	790,405		$	1,855,691
Additions	1,887			—
Purchase adjustments	—			656
Amortization	(33,072		)	—
Foreign currency translation adjustments	2,191			7,675
Balance at March 31, 2014	$	761,411		$	1,864,022

Cash paid for purchases of intangible assets during the three-month periods ended March 31, 2014 totaled $1.9 million.

The changes in the carrying amount of goodwill for the three months ended March 31, 2014 resulted primarily from changes in foreign currency translation together with the adjustments made in connection with the finalization of the purchase price allocation for acquisition of Ingenuity discussed in Note 3.

For the three-month periods ended March 31, 2014 and 2013, amortization expense on intangible assets totaled approximately $33.1 million and $29.6 million, respectively. Amortization of intangibles for the next five years is expected to be approximately:



Year	Annual Amortization (in thousands)
2015	$	133,037
2016	$	129,825
2017	$	115,041
2018	$	89,890
2019	$	67,984


7.	Derivatives

In the ordinary course of business, we use derivative instruments, including swaps, forwards and/or options, to manage potential losses from foreign currency exposures and variable rate debt. The principal objective of such derivative instruments is to minimize the risks and/or costs associated with our global financial and operating activities. We do not utilize derivative or other financial instruments for trading or other speculative purposes. We recognize all derivatives as either assets or liabilities on the balance sheet on a gross basis, measure those instruments at fair value and recognize the change in fair value in earnings in the period of change, unless the derivative qualifies as an effective hedge that offsets certain exposures. We do not offset the fair value of derivative instruments with cash collateral held or received from the same counterparty under a master netting arrangement. As of March 31, 2014 we did not have any derivatives that were accounted for as hedging instruments.

Call Options

We entered into Call Options which, along with the sale of the Warrants, represent the Call Spread Overlay entered into in connection with the Cash Convertible Notes and which are more fully described in Note 9, “Debt”. We used $105.2 million of the proceeds from the issuance of the Cash Convertible Notes to pay the premium for the Call Options, and simultaneously received $69.4 million from the sale of the Warrants, for a net cash outlay of $35.8 million for the Call Spread Overlay. The Call Options are intended to offset cash payments in excess of the principal amount due upon any conversion of the Cash Convertible Notes.

Aside from the initial payment of a premium of $105.2 million for the Call Options, we will not be required to make any cash payments under the Call Options. We will however be entitled to receive under the terms of the Call Options an amount of cash generally equal to the amount by which the market price per share of our common stock exceeds the exercise price of the Call Options during the relevant valuation period. The exercise price under the Call Options is equal to the conversion price of the Cash Convertible Notes.

The Call Options, for which our common stock is the underlying security, are a derivative asset that requires mark-to-market accounting treatment due to the cash settlement features until the Call Options settle or expire. The Call Options are measured and reported at fair value on a recurring basis, within Level 3 of the fair value hierarchy. For further discussion of the inputs used to

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determine the fair value of the Call Options, refer to Note 8, “Fair Value Measurements.” The fair value of the Call Options at March 31, 2014 was approximately $101.1 million.

The Call Options do not qualify for hedge accounting treatment. Therefore, the change in fair value of these instruments is recognized immediately in our Consolidated Statements of Income in other (expense) income, net. For the three months ended March 31, 2014, the change in the fair value of the Call Options resulted in gains of $4.1 million. Because the terms of the Call Options are substantially similar to those of the Cash Convertible Notes' embedded cash conversion option, discussed below, we expect the net effect of those two derivative instruments on our earnings to be minimal.

Cash Convertible Notes Embedded Cash Conversion Option

The embedded cash conversion option within the Cash Convertible Notes is required to be separated from the Cash Convertible Notes and accounted for separately as a derivative liability, with changes in fair value reported in our Consolidated Statements of Income in other (expense) income, net until the cash conversion option settles or expires. For further discussion of the Cash Convertible Notes, refer to Note 9 “Debt”. The initial fair value liability of the embedded cash conversion option was $105.2 million, which simultaneously reduced the carrying value of the Cash Convertible Notes (effectively an original issuance discount). The embedded cash conversion option is measured and reported at fair value on a recurring basis, within Level 3 of the fair value hierarchy. For further discussion of the inputs used to determine the fair value of the embedded cash conversion option, refer to Note 8, “Fair Value Measurements.” The fair value of the embedded cash conversion option at March 31, 2014 was approximately $101.3 million. For the three months ended March 31, 2014, the change in the fair value of the embedded cash conversion option resulted in losses of $3.8 million. This loss was slightly lower than the gain recognized on the Call Options over the same period.

Foreign Currency Derivatives

As a globally active enterprise, we are subject to risks associated with fluctuations in foreign currencies in our ordinary operations. This includes foreign currency-denominated receivables, payables, debt, and other balance sheet positions including intercompany items. We manage balance sheet exposure on a group-wide basis using foreign exchange forward contracts, foreign exchange options and cross-currency swaps.

Undesignated Derivative Instruments

We are party to various foreign exchange forward, option and swap arrangements which had, at March 31, 2014, an aggregate notional value of $876.6 million and fair value of $2.9 million included in prepaid and other assets and $6.5 million included in accrued and other liabilities, respectively, and which expire at various dates through January 2015.

We were party to various foreign exchange forward and swap arrangements which had, at December 31, 2013, an aggregate notional value of $842.1 million and fair values of $2.5 million and $14.5 million which are included in other assets and other liabilities, respectively, and which expired at various dates through April 2014. The transactions have been entered into to offset the effects from short-term balance sheet exposure to foreign currency exchange risk. Changes in the fair value of these arrangements have been recognized in other (expense) income, net.

The transactions were entered into to offset the effects from short-term balance sheet exposure to foreign currency exchange risk. Changes in the fair value of these arrangements were recognized in other (expense) income, net.

Fair Values of Derivative Instruments

The following table summarizes the fair value amounts of derivative instruments reported in the condensed consolidated balance sheets as of March 31, 2014 and December 31, 2013:



	Derivatives in Asset Positions Fair value				Derivatives in Liability Positions Fair value
(in thousands)	3/31/2014		12/31/2013		3/31/2014			12/31/2013
Undesignated derivative instruments
Call spread overlay	$	101,070	$	—	$	(101,341	)	$	—
Foreign exchange contracts	2,869		2,533		(6,480		)	(14,518		)
Total derivative instruments	$	103,939	$	2,533	$	(107,821	)	$	(14,518	)

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Gains and Losses on Derivative Instruments

The following tables summarize the locations and gains and losses on derivative instruments for the three months ended March 31, 2014 and 2013:



Three months ended March 31, 2014 (in thousands)	Gain/(loss) recognized in AOCI	Location of (gain) loss in income statement	(Gain) loss reclassified from AOCI into income	Gain (loss) recognized in income
Undesignated derivative instruments
Call spread overlay	n/a	Other income, net	n/a	$	(271	)
Foreign exchange contracts	n/a	Other income, net	n/a	1,035
				$	764

Three months ended March 31, 2013 (in thousands)	Gain/(loss) recognized in AOCI	Location of (gain) loss in income statement	(Gain) loss reclassified from AOCI into income	Gain (loss) recognized in income
Undesignated derivative instruments
Foreign exchange contracts	n/a	Other income, net	n/a	$	16,784

The amounts noted in the tables above for accumulated other comprehensive income (AOCI) do not include any adjustments for the impact of deferred income taxes. Gains and losses recognized on foreign exchange contracts are included in other (expense) income, net in the condensed consolidated statements of income together with the corresponding, offsetting foreign exchange losses and gains on the underlying transactions.


8.	Fair Value Measurements

Assets and liabilities are measured at fair value according to a three-tier fair value hierarchy which prioritizes the inputs used in measuring fair value as follows:

Level 1. Observable inputs, such as quoted prices in active markets;

Level 2. Inputs, other than the quoted price in active markets, that are observable either directly or indirectly; and

Level 3. Unobservable inputs in which there is little or no market data, which require the reporting entity to develop its own assumptions.

Our assets and liabilities measured at fair value on a recurring basis consist of short-term investments, which are classified in Level 1 and Level 2 of the fair value hierarchy, derivative contracts used to hedge currency and interest rate risk, which are classified in Level 2 of the fair value hierarchy, and contingent consideration accruals and derivative financial instruments entered into in connection with the Cash Convertible Notes discussed in Note 9, which are classified in Level 3 of the fair value hierarchy, and are shown in the tables below.

In determining fair value for Level 2 instruments, we apply a market approach, using quoted active market prices relevant to the particular instrument under valuation, giving consideration to the credit risk of both the respective counterparty to the contract and the Company. To determine our credit risk we estimated our credit rating by benchmarking the price of outstanding debt to publicly-available comparable data from rated companies. Using the estimated rating, our credit risk was quantified by reference to publicly-traded debt with a corresponding rating.

Our Level 3 instruments include contingent consideration liabilities and derivative financial instruments. We value contingent consideration liabilities using unobservable inputs, applying the income approach, such as the discounted cash flow technique, or the probability-weighted scenario method. Contingent consideration arrangements obligate us to pay the sellers of an acquired entity if specified future events occur or conditions are met such as the achievement of technological or revenue milestones. We use various key assumptions, such as the probability of achievement of the milestones and the discount rate, to represent the non-performing risk factors and time value when applying the income approach. We regularly review the fair value of the contingent consideration, and reflect any change in the accrual in the consolidated statements of income in the line items commensurate with the underlying nature of milestone arrangements. The Level 3 derivative financial instruments include the Call Options asset and the embedded conversion option liability. See Note 9, "Debt", and Note 7, "Derivatives", for further information. The derivatives are not actively traded and are valued based on an option pricing model that uses observable and unobservable market data for inputs. Significant market data inputs used to determine fair values as of March 31, 2014 included our common stock price, the risk-free interest rate, and the implied volatility of our common stock. The Call Options asset and the embedded cash conversion option liability were designed with the

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intent that changes in their fair values would substantially offset, with limited net impact to our earnings. Therefore, the sensitivity of changes in the unobservable inputs to the option pricing model for such instruments is substantially mitigated.

The following table presents our fair value hierarchy for our financial assets and liabilities measured at fair value on a recurring basis as of March 31, 2014 and December 31, 2013:



	As of March 31, 2014										As of December 31, 2013
(in thousands)	Level 1		Level 2		Level 3			Total			Level 1		Level 2			Level 3			Total
Assets:
Short-term investments	$	—	$	—	$	—		$	—		$	8,550	$	41,373		$	—		$	49,923
Call Option	—		—		101,070			101,070			—		—			—			—
Foreign exchange contracts	—		2,869		—			2,869			—		2,533			—			2,533
	$	—	$	2,869	$	101,070		$	103,939		$	8,550	$	43,906		$	—		$	52,456
Liabilities:
Foreign exchange contracts	$	—	$	—	$	—		$	—		$	—	$	(14,518	)	$	—		$	(14,518	)
Cash Conversion Option	—		—		(101,341		)	(101,341		)	—		—			—			—
Contingent consideration	—		—		(5,061		)	(5,061		)	—		—			(6,127		)	(6,127		)
	$	—	$	—	$	(106,402	)	$	(106,402	)	$	—	$	(14,518	)	$	(6,127	)	$	(20,645	)

For liabilities with Level 3 inputs, the following table summarizes the activity for the three months ended March 31, 2014:



(in thousands)	Call Option			Cash Conversion Option			Contingent Consideration
Beginning Balance at December 31, 2013	$	—		$	—		$	(6,127	)
Additions	105,170			(105,170		)	—
Payments	—			—			—
Gain (loss) included in earnings	(4,100		)	3,829			1,068
Foreign currency translation adjustments	—			—			(2		)
Ending balance at March 31, 2014	$	101,070		$	(101,341	)	$	(5,061	)

During 2014, a gain for the reduction in the fair value of contingent consideration totaling $1.1 million was included in the condensed consolidated statement of income of which $1.0 million was recognized in cost of sales and $0.1 million was recognized in general and administrative, restructuring, integration and other.

The carrying values of financial instruments, including cash and equivalents, accounts receivable, accounts payable and other accrued liabilities, approximate their fair values due to their short-term maturities. The estimated fair value of long-term debt as disclosed in Note 9 was based on current interest rates for similar types of borrowings. The estimated fair values may not represent actual values of the financial instruments that could be realized as of the balance sheet date or that will be realized in the future. There were no fair value adjustments in the three-month periods ended March 31, 2014 and 2013 for nonfinancial assets or liabilities required to be measured at fair value on a nonrecurring basis other than the impairment of a cost-method investment as discussed in Note 5, "Investments".


9.	Debt

Our credit facilities available and undrawn at March 31, 2014 total €438.0 million (approximately $603.9 million). This includes a €400.0 million syndicated multi-currency revolving credit facility expiring December 2016 of which no amounts were utilized at March 31, 2014 or at December 31, 2013, and four other lines of credit amounting to €38.0 million with no expiration date, none of which were utilized as of March 31, 2014 or as of December 31, 2013. The €400.0 million facility can be utilized in euro, U.K. pound or U.S. dollar and bears interest of 0.8% to 2.35% above three months EURIBOR, or LIBOR in relation to any loan not in euro, and is offered with interest periods of one, two, three, six or twelve months. The commitment fee is calculated based on 35% of the applicable margin. The revolving facility agreement contains certain financial and non-financial covenants, including but not limited to, restrictions on the encumbrance of assets and the maintenance of certain financial ratios. We were in compliance with these covenants at March 31, 2014. The credit facilities are for general corporate purposes.

At March 31, 2014, total long-term debt was approximately $1.2 billion, $0.4 million of which is current.

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Total long-term debt consists of the following:



(in thousands)	March 31, 2014		December 31, 2013
Notes payable to QIAGEN Euro Finance bearing interest at an effective rate of 3.7% repaid in March 2014	$	—	$	300,000
Notes payable to QIAGEN Finance bearing interest at an effective rate of 1.8% due in February 2024	145,000		145,000
3.19% Series A Senior Notes due October 2019	73,000		73,000
3.75% Series B Senior Notes due October 2022	300,000		300,000
3.90% Series C Senior Notes due October 2024	27,000		27,000
0.375% Senior Unsecured Cash Convertible Notes due 2019	379,122		—
0.875% Senior Unsecured Cash Convertible Notes due 2021	246,208		—
Other notes payable bearing interest up to 6.28% and due through November 2015	966		483
Total long-term debt	1,171,296		845,483
Less current portion	414		207
Long-term portion	$	1,170,882	$	845,276

Cash Convertible Notes due 2019 and 2021

On March 19, 2014, we issued $730.0 million aggregate principal amount of Cash Convertible Senior Notes of which $430.0 million is due in 2019 (2019 Notes) and $300.0 million is due in 2021 (2021 Notes). We refer to the 2019 Notes and 2021 Notes, collectively as the “Cash Convertible Notes”. The aggregate net proceeds of the Cash Convertible Notes was $686.9 million, after payment of the net cost of the Call Spread Overlay described below and transaction costs, excluding approximately $5.8 million of accrued debt issuance costs at March 31, 2014. Additionally, we used $372.5 million of the net proceeds to repay the 2006 Notes and related subscription right described below.

Interest on the Cash Convertible Notes is payable semiannually in arrears on March 19 and September 19 of each year, at rates of 0.375% and 0.875% per annum for the 2019 Notes and 2021 Notes, respectively, commencing on September 19, 2014. The 2019 Notes will mature on March 19, 2019 and the 2021 Notes will mature on March 19, 2021, respectively, unless repurchased or converted in accordance with their terms prior to such date.

The Cash Convertible Notes are convertible only into cash, and not into shares of our common stock or any other securities. The Cash Convertible Notes are convertible into cash in whole, but not in part, at the option of noteholders in the following circumstances: (a) from April 29, 2014 through September 18, 2018 for the 2019 Notes, and September 18, 2020 for the 2021 Notes (Contingent Conversion Period), under any of the Contingent Conversion Conditions and (b) at any time following the Contingent Conversion Period through the fifth business day immediately preceding the applicable maturity Date. Upon conversion, noteholders will receive an amount in cash equal to the Cash Settlement Amount, calculated as described below.

Noteholders may convert their Cash Convertible Notes solely into cash at their option at any time during the Contingent Conversion Period only under the following circumstances (Contingent Conversion Conditions):

•

during any calendar quarter commencing after the calendar quarter ending on March 31, 2014 (and only during such calendar quarter), if the last reported sale price of our common stock for at least 20 trading days (whether or not consecutive) during a period of 30 consecutive trading days ending on the last trading day of the immediately preceding calendar quarter is greater than or equal to 130% of the conversion price on each applicable trading day;


•	if we undergo certain fundamental changes;


•	during the five business day period immediately after any ten consecutive trading day period in which the quoted price for the 2019 Notes or the 2021 Notes for each trading day of the measurement period was less than 98% of the product of the last reported sale price of our common stock and the conversion rate on each such trading day;


•	if we elect to distribute assets or property to all or substantially all of the holders of our common stock and those assets or other property have a value of more than 25% of the average daily volume-weighted average trading price of our common stock for the prior 20 consecutive trading days;


•	if we elect to redeem the Cash Convertible Notes; or


•	if we experience certain customary events of default, including defaults under certain other indebtedness.

The initial conversion rate is 7,056.7273 shares of our common stock per $200,000 principal amount of Cash Convertible Notes (reflecting an initial conversion price of approximately $28.34 per share of common stock). Upon conversion, holders are entitled to a cash payment (Cash Settlement Amount) equal to the average of the conversion rate multiplied by the daily volume-weighted average trading price for our common stock over a 50-day period. The conversion rate is subject to adjustment in certain instances but will not be adjusted for any accrued and unpaid interest. In addition, following the occurrence of certain corporate events that may occur prior

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to the applicable maturity date, we may be required to pay a cash make-whole premium by increasing the conversion rate for any holder who elects to convert Cash Convertible Notes in connection with the occurrence of such a corporate event.

We may redeem the 2019 Notes or 2021 Notes in their entirety at a price equal to 100% of the principal amount of the applicable Cash Convertible Notes plus accrued interest if at any time 20% or less of the aggregate principal amount of the applicable Cash Convertible Notes originally issued remain outstanding.

The Cash Convertible Notes are senior unsecured obligations, and rank senior in right of payment to any of our indebtedness that is expressly subordinated in right of payment to the Cash Convertible Notes; equal in right of payment to any of our unsecured indebtedness that is unsubordinated; junior in right of payment to any of our secured indebtedness to the extent of the value of the assets securing such indebtedness; and junior to all indebtedness and other liabilities (including trade payables) of our subsidiaries.

Because The Cash Convertible Notes contain an embedded cash conversion option, we have determined that the embedded cash conversion option is a derivative financial instrument, which is required to be separated from the Cash Convertible Notes and accounted for separately as a derivative liability, with changes in fair value reported in our consolidated statements of operations until the cash conversion option transaction settles or expires. The initial fair value liability of the embedded cash conversion option was $105.2 million, which simultaneously reduced the carrying value of the Cash Convertible Notes (effectively an original issuance discount). For further discussion of the derivative financial instruments relating to the Cash Convertible Notes, refer to Note 7, “Derivatives.”

As noted above, the reduced carrying value on the Cash Convertible Notes resulted in a debt discount that is amortized to the principal amount through the recognition of non-cash interest expense over the expected life of the debt, which is five and seven years for the 2019 Notes and 2021 Notes, respectively. This resulted in our recognition of interest expense on the Cash Convertible Notes at an effective rate approximating what we would have incurred had nonconvertible debt with otherwise similar terms been issued. The effective interest rate of the 2019 and 2021 Notes is 2.937% and 3.809%, respectively, which is imputed based on the amortization of the fair value of the embedded cash conversion option over the remaining term of the Cash Convertible Notes. As of March 31, 2014, we expect the 2019 Notes to be outstanding until their 2019 maturity date and the 2021 Notes to be outstanding until their 2021 maturity date, for remaining amortization periods of approximately five and seven years, respectively. The Cash Convertible Notes’ if-converted value did not exceed their principal amount as of March 31, 2014.

In connection with the issuance of the Cash Convertible Notes, we incurred approximately $13.1 million in transaction costs. Such costs have been allocated to the Cash Convertible Notes and deferred as a long-term asset and will be amortized over the terms of the Cash Convertible Notes.

Interest expense related to the Cash Convertible Notes was comprised of the following:



	Three months ended
	March 31,
Three months ended March 31, (in thousands)	2014		2013
Coupon interest	$	130	$	—
Amortization of original issuance discount	500		—
Amortization of debt issuance costs	59		—
Total interest expense related to the Cash Convertible Notes	$	689	$	—

Cash Convertible Notes Call Spread Overlay

Concurrent with the issuance of the Cash Convertible Notes, we entered into privately negotiated hedge transactions (Call Options) with, and issued warrants to purchase shares of our common stock (Warrants) to, certain financial institutions. We refer to the Call Options and Warrants collectively as the “Call Spread Overlay”. The Call Options are intended to offset any cash payments payable by us in excess of the principal amount due upon any conversion of the Cash Convertible Notes. We used $105.2 million of the proceeds from the issuance of the Cash Convertible Notes to pay for the Call Options, and simultaneously received $69.4 million from the sale of the Warrants, for a net cash outlay of $35.8 million for the Call Spread Overlay. The Call Options are derivative financial instruments and is discussed further in Note 7, “Derivatives.” The Warrants are equity instruments and are further discussed in Note 12, “Equity.”

Aside from the initial payment of a premium of $105.2 million for the Call Option, we will not be required to make any cash payments under the Call Options, and will be entitled to receive an amount of cash, generally equal to the amount by which the market price per share of our common stock exceeds the exercise price of the Call Options during the relevant valuation period. The exercise price under the Call Options is initially equal to the conversion price of the Cash Convertible Notes.

The Warrants cover an aggregate of 25.8 million shares of our common stock (subject to anti-dilution adjustments under certain circumstances) and have an initial exercise price of $32.085 per share, subject to customary adjustments. The Warrants expire as

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follows: Warrants to purchase 15.2 million shares expire over a period of 50 trading days beginning on December 27, 2018 and Warrants to purchase 10.6 million shares expire over a period of 50 trading days beginning on December 29, 2020. The Warrants are European-style (exercisable only upon expiration). The Warrants could have a dilutive effect to the extent that the price of our common stock exceeds the applicable strike price of the Warrants. For each Warrant that is exercised, we will deliver to the holder a number of shares of our common stock equal to the amount by which the settlement price exceeds the exercise price, divided by the settlement price, plus cash in lieu of any fractional shares. We will not receive any additional proceeds if the Warrants are exercised.

Private Placement

In October 2012, we completed a private placement through the issuance of new senior unsecured notes at a total amount of $400 million with a weighted average interest rate of 3.66% (settled on October 16, 2012). The notes were issued in three series: (1) $73 million 7-year term due in 2019 (3.19%); (2) $300 million 10-year term due in 2022 (3.75%); and (3) $27 million 12-year term due in 2024 (3.90%). We paid $2.1 million in debt issue costs which are being amortized through interest expense over the lifetime of the notes. The note purchase agreement contains certain financial and non-financial covenants, including but not limited to, restrictions on priority indebtedness and the maintenance of certain financial ratios. We were in compliance with these covenants at March 31, 2014. Based on an estimation using the changes in the U.S. Treasury rates, the fair value of these senior notes at March 31, 2014 was approximately $380.5 million.

2006 Notes

In May 2006, we completed the offering of $300 million of 3.25% Senior Convertible Notes due in 2026 (2006 Notes) through an unconsolidated subsidiary, QIAGEN Euro Finance (Euro Finance). The net proceeds of the 2006 Notes were loaned by Euro Finance to consolidated subsidiaries and at December 31, 2013, $300 million is included in long-term debt for the loan amounts payable to Euro Finance. These long-term notes payable to Euro Finance had an effective interest rate of 3.7% and were due in May 2026. Interest was payable semi-annually in May and November. The 2006 Notes were issued at 100% of the principal amount, and were convertible into 15.0 million common shares at the option of the holders upon the occurrence of certain events, at a price of $20.00 per share, subject to adjustment. QIAGEN N.V. had an agreement with QIAGEN Euro Finance to issue shares to the note holders in the event of conversion. This subscription right, along with the related receivable, was recorded at fair value in the equity of QIAGEN N.V. as paid-in capital. In March 2014, we redeemed the $300 million loan payable to Euro Finance and approximately 98% of the subscription right with QIAGEN Euro Finance for $372.5 million, and recognized a loss on the redemption of $4.6 million in other (expense) income, net.

2004 Notes

In August 2004, we completed the sale of $150 million of 1.5% Senior Convertible Notes due in 2024 (2004 Notes), through our unconsolidated subsidiary QIAGEN Finance. The net proceeds of the 2004 Notes were loaned by QIAGEN Finance to consolidated subsidiaries with an effective interest rate of 1.8% and at March 31, 2014 and December 31, 2013. $145 million is included in long-term debt for the loan amounts payable to QIAGEN Finance. The 2004 Notes are due in February 2024. Interest is payable semi-annually in February and August. The 2004 Notes were issued at 100% of principal value, and are convertible into 11.5 million common shares at the option of the holders upon the occurrence of certain events at a price of $12.6449 per share, subject to adjustment. QIAGEN N.V. has an agreement with QIAGEN Finance to issue shares to the investors in the event of conversion. This subscription right, along with the related receivable, is recorded at fair value in the equity of QIAGEN N.V. as paid-in capital. The 2004 Notes may be redeemed, in whole or in part, at QIAGEN’s option at 100% of the principal amount, provided that the actual trading price of our common shares exceeds 120% of the conversion price for twenty consecutive trading days. In addition, the holders of the 2004 Notes may require QIAGEN to repurchase all or a portion of the outstanding 2004 Notes for 100% of the principal amount, plus accrued interest, on August 18, 2014 and 2019. Based on an estimation using available over-the-counter market information on the convertible bond issued by QIAGEN Finance, the fair value of the 2004 Notes at March 31, 2014 was $240.8 million. We have reserved 11.5 million common shares for issuance in the event of conversion of the 2004 Notes.

We believe that funds from operations, existing cash and cash equivalents, and availability of financing facilities as needed, will be sufficient to fund our debt repayment obligations as they come due in the next twelve months.


10.	Income Taxes

The provision for income taxes is based upon the estimated annual effective tax rates for the year applied to the current period income before tax plus the tax effect of any significant unusual items, discrete events or changes in tax law. Our operating subsidiaries are exposed to effective tax rates ranging from zero to approximately 42%. Fluctuations in the distribution of pre-tax income among our operating subsidiaries can lead to fluctuations of the effective tax rate in the condensed consolidated financial statements. In the three-month periods ended March 31, 2014 and 2013, the effective tax rates were 16.4% and 11.9%, respectively.

We assess uncertain tax positions in accordance with ASC 740 (ASC 740-10 Accounting for Uncertainties in Tax). At March 31, 2014, our net unrecognized tax benefits totaled approximately $11.8 million which, if recognized, would favorably impact our effective tax rate in the periods in which they are recognized. It is possible that approximately $0.4 million of the unrecognized tax benefits may be

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released during the next 12 months due to lapse of statutes of limitations or settlements with tax authorities. We cannot reasonably estimate the range of the potential outcomes of these matters.

We conduct business globally and, as a result, file numerous consolidated and separate income tax returns in The Netherlands, Germany, Switzerland and the U.S. federal jurisdiction, as well as in various other state and foreign jurisdictions. In the normal course of business, we are subject to examination by taxing authorities throughout the world. Our subsidiaries are generally no longer subject to income tax examinations by tax authorities for years before 2008. Currently, the U.S. tax authority (Internal Revenue Service) is examining our U.S. federal tax returns for 2011 and 2012. The audit is still in the early stage and the outcome is not assessable at this time.

As of March 31, 2014, residual Netherlands income taxes have not been provided on the undistributed earnings of the majority of our foreign subsidiaries as these earnings are considered to be either permanently reinvested or can be repatriated tax free.


11.	Inventories

The components of inventories consist of the following as of March 31, 2014 and December 31, 2013:



(in thousands)	March 31, 2014		December 31, 2013
Raw materials	$	23,414	$	24,975
Work in process	24,500		25,535
Finished goods	85,498		77,587
Total inventories	$	133,412	$	128,097


12.	Equity

Issuance of Warrants

During March 2014, in connection with the issuance of our Cash Convertible Notes, we issued warrants (as described in Note 9, “Debt”) for approximately 25.8 million shares of our common stock (subject to antidilution adjustments under certain circumstances) with an initial exercise price of $32.085 per share, subject to customary adjustments. The net proceeds from the sale of the Warrants of approximately $69.4 million are included as additional paid in capital in the accompanying balance sheet as of March 31, 2014. The Warrants expire as follows: warrants to purchase 15.2 million shares expire over a period of 50 trading days beginning on December 27, 2018 and Warrants to purchase 10.6 million shares expire over a period of 50 trading days beginning on December 29, 2020. The Warrants are exercisable only upon expiration. For each Warrant that is exercised, we will deliver to the holder a number of shares of our common stock equal to the amount by which the settlement price exceeds the exercise price, divided by the settlement price, plus cash in lieu of any fractional shares. The Warrants could separately have a dilutive effect on shares of our common stock to the extent that the market value per share of our common stock exceeds the applicable exercise price of the Warrants (as measured under the terms of the Warrants).

Share Repurchase Program

In 2012, our Supervisory Board approved a program authorizing management to purchase up to a total of $100 million of our common shares (excluding transaction costs). We completed this share repurchase program in April 2013 having repurchased, between October 2012 and April 2013, a total of 5.1 million QIAGEN shares for an aggregate cost of $99.0 million.

In July 2013, we announced our intention to exercise the authorization granted by the Annual General Meeting of Shareholders on June 26, 2013, to purchase up to $100 million of our common shares (excluding transaction costs). Based on the closing price on July 29, 2013, this represents approximately five million shares. In 2013, 1.0 million QIAGEN shares were repurchased for $22.7 million and 1.9 million QIAGEN shares were repurchased for $43.3 million in the first quarter of 2014, under this program.

The cost of repurchased shares is included in treasury stock and reported as a reduction in total equity when a repurchase occurs. Repurchased shares will be held in treasury in order to satisfy various obligations, which include exchangeable debt instruments and employee share-based remuneration plans.

Accumulated Other Comprehensive Income (Loss)

The following table is a summary of the components of accumulated other comprehensive income as of March 31, 2014 and December 31, 2013:

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(in thousands)	March 31, 2014			December 31, 2013
Net unrealized gain on pension, net of tax	$	(401	)	$	(401	)
Foreign currency effects from intercompany long-term investment transactions, net of tax of $6.6 million and $6.5 million in 2014 and 2013, respectively	10,267			12,164
Foreign currency translation adjustments	(2,238		)	(15,955		)
Accumulated other comprehensive income (loss)	$	7,628		$	(4,192	)


13.	Earnings per Common Share

We present basic and diluted earnings per share. Basic earnings per share is calculated by dividing the net income attributable to the owners of QIAGEN N.V. by the weighted average number of common shares outstanding. Diluted earnings per share reflect the potential dilution that would occur if all “in the money” securities to issue common shares were exercised. The following table summarizes the information used to compute earnings per common share:



	Three months ended
	March 31,
(in thousands, except per share data)	2014		2013
Net income attributable to the owners of QIAGEN N.V.	$	23,267	$	19,983

Weighted average number of common shares used to compute basic net income per common share	232,856		233,325
Dilutive effect of warrants	6,525		4,695
Dilutive effect of stock options and restricted stock units	3,565		3,430
Weighted average number of common shares used to compute diluted net income per common share	242,946		241,450
Outstanding options and awards having no dilutive effect, not included in above calculation	498		1,501
Outstanding warrants having no dilutive effect, not included in above calculation	19,943		21,772

Basic earnings per common share attributable to the owners of QIAGEN N.V.	$	0.10	$	0.09
Diluted earnings per common share attributable to the owners of QIAGEN N.V.	$	0.10	$	0.08

Holders of the Warrants issued in connection with the Call Spread Overlay discussed in Note 9 may acquire up to 25.8 million shares of our common stock at an exercise price of $32.085. If the market price per share of our common stock for the period in which the Warrants are exercised exceeds the established exercise price of the Warrants, the Warrants will have a dilutive effect on our earnings per common share using the treasury method. The average stock price during the period ending March 31, 2014 did not exceed the exercise price of the Warrants. Holders of the Cash Convertible Notes may, under certain circumstances at their option, convert into cash and not shares of common stock. Therefore the Cash Convertible notes are excluded from the calculation of dilutive shares.


14.	Commitments and Contingencies

Contingent Consideration Commitments

Pursuant to the purchase agreements for certain acquisitions, we could be required to make additional contingent cash payments totaling up to $115.9 million based on the achievement of certain revenue and operating results milestones as follows: $61.3 million in the remainder of 2014, $16.5 million in 2015, $17.8 million in 2016, $7.0 million in 2017, and $13.3 million payable in any 12-month period from now through 2017 based on the accomplishment of certain revenue targets. Of the $115.9 million total contingent obligation, $41.4 million if earned would be recorded as an adjustment to goodwill. Of the remaining $74.5 million, we have assessed the fair value at March 31, 2014 to be $5.1 million, which is included in accrued and other liabilities as of March 31, 2014.

Preacquisition Contingencies

In connection with certain acquisitions, amounts were paid into escrow accounts to cover certain preacquisition contingencies assumed in the acquisition. The escrow amounts that can be claimed by QIAGEN are recorded as an asset in prepaid and other expenses and amount to $2.5 million as of March 31, 2014 ($2.5 million as of December 31, 2013). In addition, we have recorded $0.1

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million for preacquisition contingencies as a liability under accrued and other liabilities as of March 31, 2014 ($0.1 million as of December 31, 2013).

Contingencies

In the ordinary course of business, we provide a warranty to customers that our products are free of defects and will conform to published specifications. Generally, the applicable product warranty period is one year from the date of delivery of the product to the customer or of site acceptance, if required. Additionally, we typically provide limited warranties with respect to our services. From time to time, we also make other warranties to customers, including warranties that our products are manufactured in accordance with applicable laws and not in violation of third-party rights. We provide for estimated warranty costs at the time of the product sale. We believe our warranty reserves of $4.9 million as of March 31, 2014 and December 31, 2013, appropriately reflect the estimated cost of such warranty obligations.

Litigation

From time to time, QIAGEN may be party to legal proceedings incidental to its business. As of March 31, 2014, certain claims, suits or legal proceedings arising out of the normal course of business have been filed or were pending against QIAGEN or its subsidiaries. These matters have arisen in the ordinary course and conduct of business, as well as through acquisition. Although it is not possible to predict the outcome of such litigation, we assess the degree of probability and evaluate the reasonably possible losses that we could incur as a result of these matters. We accrue for any estimated loss when it is probable that a liability has been incurred and the amount of probable loss can be estimated. Based on the facts known to QIAGEN and after consultation with legal counsel, management believes that such legal proceedings will not have a material adverse effect on QIAGEN’s financial position or results of operations.


15.	Share-Based Compensation

Stock Options

During the three-month period ended March 31, 2014, we did not grant any options to purchase common shares, compared to 0.3 million common shares granted for the three-month month period ended March 31, 2013.

The unrecognized share-based compensation expense related to employee stock option awards, less estimated forfeitures, was approximately $2.6 million, as of March 31, 2014 which will be recognized over a period of 1.47 years.

Stock Units

Stock units represent rights to receive Common Shares at a future date and include restricted stock units which are subject to time-vesting only and performance stock units which include performance conditions in addition to time-vesting. During the three-month period ended March 31, 2014, we granted 0.7 million stock awards compared to 1.0 million stock awards for the three-month period ended March 31, 2013.

At March 31, 2014, there was $128.0 million remaining in unrecognized compensation expense, less estimated forfeitures, related to these awards which will be recognized over a period of 3.17 years.

Share-Based Compensation Expense

Total share-based compensation expense for the three-month periods ended March 31, 2014 and 2013 is comprised of the following:



	Three months ended
	March 31,
Compensation Expense (in thousands)	2014		2013
Cost of sales	$	812	$	848
Research and development	2,084		1,547
Sales and marketing	2,733		2,676
General and administrative, restructuring, integration and other	4,516		3,526
Share-based compensation expense before taxes	10,145		8,597
Less: income tax benefit	2,312		2,000
Net share-based compensation expense	$	7,833	$	6,597

No compensation cost was capitalized in inventory at March 31, 2014 or December 31, 2013 as the amounts were not material.

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16.	Related Party Transactions

From time to time, we engage in transactions with companies in which we hold interests all of which are individually and in the aggregate immaterial except for certain transactions as discussed below.

We have a 100% interest in QIAGEN Finance (Luxembourg) S.A. (QIAGEN Finance) and QIAGEN Euro Finance (Luxembourg) S.A. (Euro Finance), which were established for the purpose of issuing convertible debt. As discussed in Note 9, QIAGEN Finance and Euro Finance are variable interest entities with no primary beneficiary, thus they are not consolidated. Accordingly, the convertible debt is not included in the consolidated statements of QIAGEN N.V., though QIAGEN N.V. does report the full obligation of the debt through its liabilities to QIAGEN Finance and Euro Finance. As of March 31, 2014 and December 31, 2013, we had loans payable to QIAGEN Finance of $145.0 million, accrued interest due to QIAGEN Finance of $1.4 million and $4.3 million, respectively and amounts receivable from QIAGEN Finance of $1.0 million and $3.4 million, respectively. As of December 31, 2013, we had a loan payable to Euro Finance of $300.0 million, accrued interest due to Euro Finance of $2.6 million and amounts receivable from Euro Finance of $1.3 million. As of March 31, 2014, the loan payable to Euro Finance has been redeemed together with all accrued interest. The amounts receivable are related to subscription rights which are recorded net in the equity of QIAGEN N.V. as paid-in capital.

In June 2013, we collected $1.6 million from a loan receivable due from a company in which we also hold an interest.

During 2012, we entered into a development and license agreement with a company in which we also hold an interest. Under the terms of this agreement we paid a total of $7.7 million in 2013 and another $2.0 million will become due through 2015 based on the achievement of certain milestones.


17.	Subsequent Event

Since April 1, 2014 and settled through April 25, 2014, we have repurchased 641,792 QIAGEN shares on the Frankfurt Stock Exchange at a volume-weighted average price of €15.08 (approximately €9.7 million, or $13.4 million in total) under the share repurchase program discussed more fully in Note 12 "Equity".

OPERATING AND FINANCIAL REVIEW AND PROSPECTS

This section contains a number of forward-looking statements. These statements are based on current management expectations, and actual results may differ materially. Among the factors that could cause actual results to differ from management’s expectations are those described in “Risk Factors” and “Forward-looking and Cautionary Statements” below.

Forward-looking and Cautionary Statements

This report contains forward-looking statements that are subject to risks and uncertainties. These statements can be identified by the use of forward-looking terminology, such as “believe,” “hope,” “plan,” “intend,” “seek,” “may,” “will,” “could,” “should,” “would,” “expect,” “anticipate,” “estimate,” “continue” or other similar words. Such statements are based on management’s current expectations and are subject to a number of factors and uncertainties that could cause actual results to differ materially from those described in the forward-looking statements. We caution investors that there can be no assurance that actual results or business conditions will not differ materially from those projected or suggested in such forward-looking statements as a result of various factors, including, but not limited to, the following: risks associated with our expansion of operations, including the acquisition of new businesses; variability in our operating results from quarter to quarter; management of growth, international operations, and dependence on key personnel; intense competition; technological change; our ability to develop and protect proprietary products and technologies and to enter into and maintain collaborative commercial relationships; our future capital requirements; general economic conditions and capital market fluctuations; and uncertainties as to the extent of future government regulation of our business. As a result, our future success involves a high degree of risk. For further information, refer to the more specific risks and uncertainties discussed in Part 1, Item 3 "Key Information" of our Annual Report on Form 20-F for the year ended December 31, 2013.

Results of Operations

Overview

We are the world's leading provider of innovative Sample & Assay Technologies, based on independent market studies of United States and European market shares for our products and technologies. Our automated systems and consumable products empower customers to transform raw biological samples into valuable molecular information. Sample technologies are used to isolate DNA, RNA and proteins from any biological sample, such as blood or tissue. Assay technologies are then used to amplify, enrich and provide results for analysis of biomolecules, such as the DNA of a virus or a mutation of a gene.

We sell our products, sample and assay kits known as consumables and automated instrumentation systems using those technologies, to four major customer classes:

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•	Molecular Diagnostics-healthcare providers supporting many aspects of patient care including prevention, profiling of diseases, personalized healthcare and point of need testing


•	Applied Testing- government or industry customers using molecular technologies in fields such as forensics, veterinary diagnostics and food safety testing


•	Pharma-drug discovery and development efforts of pharmaceutical and biotechnology companies


•	Academia-researchers exploring the secrets of life such as the mechanisms and pathways of diseases, and in some cases translating that research into drug targets or commercial applications

We market products in more than 100 countries throughout the world. We have established subsidiaries in markets we believe have the greatest sales potential, including countries throughout Europe, Asia, the Americas and Australia. We also work with specialized independent distributors and importers. As of March 31, 2014, we employed approximately 4,000 people in more than 35 locations worldwide.

We aim to continue accelerating the pace of our innovation and growth in 2014 by executing on initiatives to expand our leadership in addressing the rapidly evolving needs of customers to transform biological samples into valuable molecular insights. Our focus is on five growth drivers: (1) driving adoption of the QIAsymphony automation platform and expanding the test menu, (2) extending leadership in Personalized Healthcare with innovative companion diagnostics, (3) establishing the QuantiFERON-TB test as the modern gold standard for latent tuberculosis control, (4) expanding the use of bioinformatics in molecular applications, including the adoption of our Ingenuity and CLC bio franchises, and (5) creating an industry-leading portfolio of universal solutions and workflows to drive the use of next-generation sequencing (NGS) in clinical research and diagnostics.

Among recent developments in 2014:


•	QIAsymphony maintaining rapid growth pace as content menu expands


◦	FDA 510(k) clearance was granted in April 2014 for the artus C. difficile QS-RGQ MDx Kit, a diagnostic for the bacterial infection Clostridium difficile, and QIAsymphony RGQ MDx, a complete PCR sample-to-insight platform. This assay was CE-marked in December 2013, and it was developed in collaboration with IntelligentMDx under a multiyear agreement.


◦	An FDA 510(k) submission is set to be completed in May 2014 for the artus VanR QS-RGQ Kit, another assay in the healthcare-associated infection test menu for QIAsymphony, and it was also CE-marked in March 2014. This assay is intended as an aid to identify, prevent, and control vancomycin-resistant bacterial infections.


◦	After surpassing 1,000 cumulative placements in 2013, QIAGEN is on track for 250 new annual QIAsymphony placements based on placements achieved in the first quarter of 2014.


•	Personalized Healthcare leadership gaining momentum


◦	New co-development agreements were reached in the first quarter of 2014 with existing and new pharmaceutical company partners, including solutions for the use of liquid biopsies to gain access to biological samples without costly and invasive surgical procedures. QIAGEN currently has more than 20 co-development and / or co-commercialization projects under way with pharma partners.


◦	QIAGEN began the launch in April 2014 of the first sample preparation kits for processing nucleic acids from exosomes, which are tiny enclosures that circulate in the blood and other body fluids carrying genomic information.


•	QuantiFERON-TB expanding rapidly around the world


◦	QuantiFERON-TB, the leading test for diagnosis of latent tuberculosis infections, was launched in China on March 24, 2014 in conjunction with World TB Day.


•	Bioinformatics tools driving the advancement of NGS technologies


◦	The CLC Cancer Research Workbench was launched at the American Association for Cancer Research (AACR) meeting in April 2014 as the first comprehensive, cancer-focused bioinformatics solution that can be personalized by researchers.


◦	More than 20 laboratories are now participating in the early access program for Ingenuity^® Clinical, a web-based solution

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designed to address challenges of scale, speed and decision support that healthcare laboratories face with the adoption of NGS-based applications.


◦	The GeneGlobe web portal has been expanded to offer interactive access to the extensive genomic content of the Ingenuity Knowledge Base making it easier and faster for customers to identify QIAGEN assays that best support their research.


◦	A milestone of 11,000 references to Ingenuity products in peer-reviewed publications was achieved in 2014, reaffirming the gold standard of these biological interpretation solutions.


•	Innovative NGS workflows and universal solutions helping to address clinical needs

◦

Five new sample technology kits were launched in early 2014 that provide solutions for the important and challenging tasks of gaining access to nucleic acids from clinical samples for NGS analysis. These include the REPLI-g Single Cell Kit and the REPLI-g Cell WGA & WTA Kit, which address the fast-growing demand created by the choice of single-cell analysis as “the method of the year” in 2013 by Nature Methods.


◦	Development of the sample-to-insight workflow incorporating the GeneReader™ benchtop NGS sequencer is progressing, with commercialization now expected in 12 to 18 months. Teams have been addressing system integration issues through the inclusion of new chemistries and bioinformatics in the workflow.

Recent Acquisitions

We have made a number of strategic acquisitions, expanding our technology and product offerings as well as extending our geographic presence. These transactions include:

•

In August 2013, we acquired CLC bio (CLC), a global leader in bioinformatics software with a focus on next-generation sequencing (NGS). This acquisition creates a complete workflow from biological sample to valuable molecular insights. CLC bio, a privately-held company based in Aarhus, Denmark, was founded in 2005 and has created the leading commercial data analysis solutions and workbenches for NGS. CLC’s leading products are CLC Genomics Workbench, a comprehensive and user-friendly analysis package for analyzing, comparing and visualizing NGS data; and CLC Genomics Server, a flexible enterprise-level infrastructure and analysis backbone for NGS data analysis.

•

In April 2013, we acquired Ingenuity Systems, Inc. (Ingenuity), the leading provider of software solutions that efficiently and accurately analyze and interpret the biological meaning of genomic data. Ingenuity, a privately-held U.S. company based in California's Silicon Valley, created a market leading, expertly curated knowledge system of biomedical information and analysis solutions for the exploration, interpretation and analysis of complex biological systems. New technologies such as NGS are now generating more data in a single year than was created in all prior history, making the analysis and interpretation of this extensive and very complex biological data a critical success factor.

Our financial results include the contributions of our recent acquisitions from the date of acquisition, as well as costs related to the acquisitions and integrations of the acquired companies, such as the relocation and closure of certain facilities.

We determined that we operate as one business segment in accordance with ASC Topic 280, Segment Reporting. Our chief operating decision maker (CODM) makes decisions on business operations and resource allocation based on evaluations of our Company as a whole. With revenues derived from our entire product and service offerings, it is not practicable to provide a detail of revenues for each group of similar products and services or for each customer group, as full discrete financial information is not available. However, we do provide certain revenue information by customer class to allow better insight into our operations. This information is estimated using certain assumptions to allocate revenue among the customer classes.

Three-Month Period Ended March 31, 2014 compared to Three-Month Period Ended March 31, 2013

Net Sales

In the first quarter of 2014, net sales increased by 4% to $317.1 million, from $303.6 million in the first quarter of 2013, supported by higher sales of consumables and other revenues (+5%) and instruments (+3%). Total growth was comprised of about two percentage points from the bioinformatics acquisitions of Ingenuity (as of April 29, 2013) and CLC (as of August 22, 2013) and about two percentage points from the rest of the business. Currency movements did not have any significant impact on reported sales growth.

Geographic regions: Net sales rose in all regions in the first quarter of 2014, led by the Asia-Pacific / Japan region (+6%, 19% of sales). Growth in the Americas (+4%, 47% of sales) was led by Brazil and the U.S., while the growth in Europe / Middle East / Africa region (+6%, 33% of sales) was led by France, the United Kingdom, Italy and the Nordic region. The top seven emerging

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markets provided 10% of sales, as Brazil, South Korea and China delivered growth against weaker results in Russia and tender timing impacts in Mexico.

Product categories: In the first quarter of 2014, consumables and related revenues (+5%, 89% of sales) were higher in all customer classes, led by Applied Testing, Academia and Pharma. Contributions from the Ingenuity and CLC portfolios (acquired in 2013) supported underlying growth in all customer classes.

Instruments (+3%, 11% of sales) rose at a double-digit pace in the Applied Testing and Pharma customer classes, while Molecular Diagnostics rose at a single-digit pace. Academia sales were lower due to ongoing funding issues for research institutions.

Customer classes: An overview of performance in QIAGEN’s four customer classes:

Molecular Diagnostics, which contributed approximately 48% of net sales and 1% growth in the first quarter of 2014 compared to the first quarter of 2013, absorbed the impact of the expected decline in HPV testing product sales in the U.S. (-27%, 9% of sales), generating good double-digit growth from the rest of the portfolio and especially among QIAGEN’s five growth drivers. The QuantiFERON-TB latent TB test maintained its pace of growing 21% and provided approximately 7% of total sales. The growing installed base of QIAsymphony automation platforms drove double-digit growth of Profiling consumables. Personalized Healthcare sales growth was led by rising contributions from companion diagnostic assays. Global sales of HPV testing products (-24%, 12% of sales) were primarily lower as a result of the ongoing pricing competitive pressures in the U.S.

Applied Testing, which represented approximately 8% and 14% growth, delivered solid double-digit gains in both instruments and consumables, with the bioinformatics acquisitions contributing to growth.

Pharma, which represented approximately 19% of net sales with 8% growth, generated a double-digit sales expansion in instruments and a single-digit improvement in consumables, with contributions from the Ingenuity and CLC acquisitions adding to underlying growth.

Academia, which contributed approximately 24% of net sales with 6% growth, grew on higher consumables sales and contributions from the Ingenuity and CLC bio acquisitions, which more than offset weaker instrument sales. Government funding levels are expected to improve in the second half of 2014, particularly in the U.S. and Europe, but are likely to remain below levels seen in previous years.

Gross Profit

Gross profit was $210.1 million (66% of net sales) for the three-month period ended March 31, 2014, as compared to $200.0 million (66% of net sales) in the same period in 2013. Generally, our consumable sample and assay products have a higher gross margin than our instrumentation products and service arrangements. Fluctuations in the sales levels of these products and services can result in fluctuations in gross margin between periods. Further, amortization expense related to developed technology and patent and license rights, which have been acquired in business combinations, is included in cost of sales. In the first quarter of 2014, the amortization expense on acquisition-related intangibles within cost of sales increased to $20.2 million compared to $18.0 million in the 2013 period. We expect that our acquisition-related intangible amortization will increase as a result of future acquisitions.

Research and Development

Research and development expenses increased by 18% to $40.3 million (13% of net sales) in the first quarter of 2014, compared to $34.3 million (11% of net sales) in the same period of 2013. The increase in research and development expense in 2014 primarily reflects the 2013 acquisitions. Our business combinations, along with the acquisition of new technologies, may continue to increase our research and development costs. As we continue to discover, develop and acquire new products and technologies, we expect to incur additional expenses related to facilities, licenses and employees engaged in research and development efforts. Additionally, research and development costs are expected to increase as a result of seeking regulatory approvals, including U.S. FDA Pre-Market Approval (PMA), U.S. FDA 510(k) clearance and EU CE approval of certain assays or instruments. We have a strong commitment to innovation and expect to continue to make investments in our research and development efforts.

Sales and Marketing

Sales and marketing expenses increased by 2% to $91.4 million (29% of net sales) in the first quarter of 2014 from $89.6 million (30% of net sales) in the same period of 2013. Sales and marketing expenses are primarily associated with personnel, commissions, advertising, trade shows, publications, freight and logistics expenses and other promotional expenses. We anticipate that sales and marketing costs will continue to increase along with new product introductions and growth in sales of our products.

General and Administrative, Restructuring, Integration and Other Costs

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General and administrative, business integration, restructuring and related costs were $26.8 million (8% of net sales) in the first quarter of 2014 as compared to $39.0 million (13% of net sales) in the first quarter of 2013. The net decrease includes $10.3 million in restructuring costs in 2013 related to internal restructuring of subsidiaries, including severance and retention costs, plus costs in connection with our acquisitions. The restructuring costs primarily relate to a project we began in late 2011 to enhance productivity by streamlining the organization and reallocating resources to strategic initiatives to help drive growth and innovation, strengthen our industry leadership position and improve longer-term profitability. This project eliminated organizational layers and overlapping structures, actions that will enhance our processes, speed and productivity. In connection with the integration of the acquired companies, we aim to improve efficiency in general and administrative operations. As we further integrate the acquired companies and pursue other opportunities to gain efficiencies, we expect to continue to incur additional business integration costs in 2014. Over time, we believe the integration and restructuring activities will reduce expenses as we improve efficiency in operations.

Acquisition-Related Intangible Amortization

Amortization expense related to developed technology and patent and license rights acquired in a business combination is included in cost of sales. Amortization of trademarks, customer base and noncompete agreements acquired in a business combination is recorded in operating expense under the caption “acquisition-related intangible amortization.” Amortization expenses of intangible assets not acquired in a business combination are recorded within cost of sales, research and development, or sales and marketing based on the use of the asset.

During the quarter ended March 31, 2014, the amortization expense on acquisition-related intangibles within operating expense increased to $9.3 million compared to $8.1 million the same period of 2013. We expect that our acquisition-related intangible amortization will increase as a result of future acquisitions.

Other (Expense) Income, net

Total other expense was $14.5 million and $6.3 million in the three-month periods ended March 31, 2014 and 2013, respectively. Included in other (expense) income, net is a $4.6 million loss recognized on the redemption of the $300 million loan payable to and subscription right with Euro Finance as discussed more fully in Note 9, "Debt". Additionally, total other (expense) income, net is primarily the result of interest expense partially offset by interest income and gains on foreign currency transactions.

Interest expense increased to $8.0 million and $7.7 million in the three-month periods ended March 31, 2014 and 2013, respectively. Interest costs primarily relate to debt, discussed in Note 9 in the accompanying notes to the condensed consolidated financial statements. Interest expense increased primarily as a result of the $400.0 million of new senior unsecured notes issued in October 2012.

For the three-month period ended March 31, 2014 and 2013, interest income was $1.0 million and $0.9 million. Interest income primarily reflects the changes in our cash and short-term investments and the changing interest rates thereon.

For the three-month period ended March 31, 2014, gains on foreign currency transactions totaled $0.7 million compared to gains of $0.5 million in the same period 2013. These gains and losses are due to foreign currency fluctuations.

Provision for Income Taxes

In the first quarters of 2014 and 2013, our effective tax rates were 16.4% and 11.9%, respectively. Our provision for income taxes is based upon the estimated annual effective tax rates. Our operating subsidiaries are exposed to effective tax rates ranging from zero to approximately 42%. Fluctuations in the distribution of pre-tax (loss) income among our operating subsidiaries can lead to fluctuations of the effective tax rate in the consolidated financial statements. Income tax expense increased in the first quarter of 2014 compared to 2013, mainly reflecting improved operating results.

Liquidity and Capital Resources

To date, we have funded our business primarily through internally generated funds, debt and private and public sales of equity. Our primary use of cash has been to support continuing operations and our investing activities, including capital expenditure requirements and acquisitions. As of March 31, 2014 and December 31, 2013, we had cash and cash equivalents of $564.3 million and $330.3 million, respectively. Cash and cash equivalents are primarily held in U.S. dollars and euros, other than those cash balances maintained in the local currency of subsidiaries to meet local working capital needs. At March 31, 2014, cash and cash equivalents had increased by $234.0 million from December 31, 2013, primarily due to cash provided by operating activities of $45.6 million and financing activities of $276.4 million partially offset by cash used in investing activities of $87.9 million. As of March 31, 2014 and December 31, 2013, we had working capital of $902.5 million and $583.9 million, respectively.

Operating Activities. For the three months ended March 31, 2014 and 2013, we generated net cash from operating activities of $45.6 million and $45.9 million, respectively. While net income was $23.3 million in the three months ended March 31, 2014, non-cash components in income included $49.1 million of depreciation and amortization and $1.2 million of impairments. Operating

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cash flows include a net decrease in working capital of $34.3 million, primarily due to increased inventories and payments made in connection with restructuring activities. Because we rely heavily on cash generated from operating activities to fund our business, a decrease in demand for our products, longer collection cycles or significant technological advances of competitors would have a negative impact on our liquidity.

Investing Activities. Approximately $87.9 million of cash was used in investing activities during the three months ended March 31, 2014, compared to $23.2 million for the same period in 2013. Investing activities during the three months ended March 31, 2014 consisted principally of $63.6 million for purchases of short-term investments and $17.3 million paid for purchases of property and equipment, including our ongoing construction projects in the U.S., as well as $1.9 million paid for intangible assets.

In recent years we have expanded of our Hilden, Germany, and Germantown, Maryland, USA facilities. There are two new small-scale expansion projects in Maryland that started in 2014 and are estimated to be completed in 2015. We anticipate being able to fund these expansions with cash generated by operating activities.

In connection with certain acquisitions, we could be required to make additional contingent cash payments totaling up to $115.9 million based on the achievement of certain revenue and operating results milestones as follows: $61.3 million in 2014, $16.5 million in 2015, $17.8 million in 2016, $7.0 million in 2017, and $13.3 million payable in any 12-month period from now through 2017 based on the accomplishment of certain revenue targets, the launch of certain products or the grant of certain patent rights. Of the $115.9 million total contingent obligation we have assessed the fair value at March 31, 2014 to be $5.1 million which is included in accrued and other liabilities as of March 31, 2014.

Financing Activities. Financing activities provided $276.4 million of cash for the three months ended March 31, 2014, compared to cash used in financing activities of $40.1 million for the three months ended March 31, 2013. The net proceeds from the issuance of the Cash Convertible Notes, including the related cash flow from the purchase of the Call Options and the issuance of the Warrants, were substantially used to fund the redemption of the 2006 Notes and subscription right as discussed in Note 9 "Debt." Additionally, cash used during the three months ended March 31, 2014 for the $43.3 million purchase of treasury shares was partially offset by $2.7 million for the issuance of common shares in connection with our stock plan.

In December 31, 2011, we entered into a €400.0 million syndicated multi-currency revolving credit facility expiring December 2016 of which no amounts were utilized at March 31, 2014. The €400.0 million facility can be utilized in euro, U.K pound or U.S. dollar and bears interest of 0.8% to 2.35% above three months EURIBOR, or LIBOR in relation to any loan not in euro, and is offered with interest periods of one, two, three, six or twelve months. We have additional credit lines totaling €38.0 million at variable interest rates, of which no amounts were utilized as of March 31, 2014. We also have capital lease obligations, including interest, in the aggregate amount of $15.4 million, and carry $1.2 billion of long-term debt, of which $0.4 million is current as of March 31, 2014.

In March 2014, we issued $730.0 million aggregate principal amount of Cash Convertible Senior Notes of which $430.0 million is due in 2019 (2019 Notes) and$300.0 million is due in 2021 (2021 Notes). We refer to the 2019 Notes and 2021 Notes, collectively as the “Cash Convertible Notes”. The aggregate net proceeds of the Cash Convertible Notes was $686.9 million, after payment of the net cost of the Call Spread Overlay described in Note 9, "Debt" and transaction costs. Interest on the Cash Convertible Notes is payable semiannually in arrears on March 19 and September 19 of each year, at rates of 0.375% and 0.875% per annum for the 2019 Notes and 2021 Notes, respectively, commencing on September 19, 2014. The 2019 Notes will mature on March 19, 2019 and the 2021 Notes will mature on March 19, 2021, respectively, unless repurchased or converted in accordance with their terms prior to such date.

We have notes payable, which are the long-term borrowings of the proceeds from the issuances of $150.0 million senior unsubordinated convertible notes, with a 1.5% coupon due in 2024 through QIAGEN Finance (2004 Notes). In March 2014, we redeemed the $300 million note and subscription right with QIAGEN Euro Finance for $372.5 million. QIAGEN Finance and Euro Finance are unconsolidated subsidiaries, which were established for this purpose. The 2004 Notes are convertible into our common shares at a conversion price of $12.6449, subject to adjustment. In connection with conversion of $5.0 million of the 2004 Notes, we repaid $5.0 million of the debt to QIAGEN Finance. At March 31, 2014, $145.0 million are included in long-term debt for the amount of the notes payable to QIAGEN Finance. The $145.0 million note payable has an effective rate of 1.8%, and had an original maturity in July 2011. We refinanced the $145.0 million note, which has a new maturity date of February 2024. QIAGEN N.V. has guaranteed the 2004 Notes and has agreements with QIAGEN Finance to issue shares to the note holders in the event of conversion. These subscription rights, along with the related receivable, are recorded at fair value in the equity of QIAGEN N.V. as paid-in capital.

In October 2012, we completed a U.S. private placement through the issuance of new senior unsecured notes at a total amount of $400 million with a weighted average interest rate of 3.66% (settled on October 16, 2012). The notes were issued in three series: (1) $73 million 7-year term due in 2019 (3.19%); (2) $300 million 10-year term due in 2022 (3.75%); and (3) $27 million 12-year

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term due in 2024 (3.90%). Approximately EUR 170 million (approximately $220 million) of proceeds from the notes were used to repay amounts outstanding under our short-term revolving credit facility. The remainder of the proceeds provides additional resources to support QIAGEN's longer-term business expansion.

In 2012, our Supervisory Board approved a program authorizing management to purchase up to a total of $100 million of our common shares (excluding transaction costs). We completed the share repurchase program in April 2013 having repurchased between October 2012 and April 2013 a total of 5.1 million QIAGEN shares for a total aggregate cost of $99.0 million.

In July 2013, we announced our intention to exercise the authorization granted by the Annual General Meeting of Shareholders on June 26, 2013, to purchase up to $100 million of our common shares (excluding transaction costs). Based on the closing price on July 29, 2013, this represents approximately 5.0 million common shares. Repurchased shares will be held in treasury in order to satisfy obligations for exchangeable debt instruments and employee share-based remuneration plans. In 2013, 1.0 million QIAGEN shares were repurchased for $22.7 million and 1.9 million QIAGEN shares were repurchased for $43.3 million in the first quarter of 2014, under this program.

We expect that cash from financing activities will continue to be impacted by issuances of our common shares in connection with our equity compensation plans and that the market performance of our stock will impact the timing and volume of the issuances. Additionally, we may make future acquisitions or investments requiring cash payments, the issuance of additional equity or debt financing.

We believe that funds from operations, existing cash and cash equivalents, together with the proceeds from our public and private sales of equity, and availability of financing facilities, will be sufficient to fund our planned operations and expansion during the coming year. However, the global economic downturn may have a greater impact on our business than currently expected, and we may experience a decrease in the sales of our products, which could impact our ability to generate cash. The availability of debt financing may be negatively impacted by the global credit crisis. If our future cash flows from operations and other capital resources are not adequate to fund our liquidity needs, we may be required to obtain additional debt or equity financing or to reduce or delay our capital expenditures, acquisitions or research and development projects. If we cannot obtain financing on a timely basis or at satisfactory terms, or implement timely reductions in our expenditures, our business could be adversely affected.

Quantitative and Qualitative Disclosures about Market Risk

Our market risk relates primarily to interest rate exposures on cash, marketable securities and borrowings and foreign currency exposures on intercompany and third-party transactions. The overall objective of our risk management is to reduce the potential negative earnings effects from changes in interest and foreign currency exchange rates. Exposures are managed through operational methods and financial instruments. We do not use financial instruments for trading or speculative purposes. Our exposure to market risk from changes in interest rates and currency exchange rates has not changed materially from our exposure as discussed in Item 11 of our Annual Report on Form 20-F for the year ended December 31, 2013.

Foreign Currency

QIAGEN N.V.’s functional currency is the U.S. dollar and our subsidiaries’ functional currencies are generally the local currencies of the respective countries in which they are located. All amounts in the financial statements of entities whose functional currency is not the U.S. dollar are translated into U.S. dollar equivalents at exchange rates as follows: (1) assets and liabilities at period-end rates, (2) income statement accounts at average exchange rates for the period, and (3) components of shareholders’ equity at historical rates. Translation gains or losses are recorded in shareholders’ equity, and transaction gains and losses are reflected in net income. The gain or loss on a foreign currency transactions in the three-month periods ended March 31, 2014 was $0.7 million net gains as compared to $0.5 million net gains in the same period of 2013 and are included in other expense, net.

Derivatives and Hedging

In the ordinary course of business, we use derivative instruments, including swaps, forwards and/or options, to manage potential losses from foreign currency exposures and variable rate debt. The principal objective of such derivative instruments is to minimize the risks and/or costs associated with global financial and operating activities. We do not utilize derivative or other financial instruments for trading or speculative purposes. We recognize all derivatives as either assets or liabilities on the balance sheet, measure those instruments at fair value and recognize the change in fair value in earnings in the period of change, unless the derivative qualifies as an effective hedge that offsets certain exposures. In determining fair value, we consider both the counterparty credit risk and our own creditworthiness. To determine our own credit risk, we estimated our own credit rating by benchmarking the price of our outstanding debt to publicly-available comparable data from rated companies. Using the estimated rating, we quantify our credit risk by reference to publicly-traded debt with a corresponding rating.

Foreign Currency Derivatives. As a globally active enterprise, we are subject to risks associated with fluctuations in foreign currencies in our ordinary operations. This includes foreign currency-denominated receivables, payables, debt, and other balance sheet

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positions. We manage our balance sheet exposure on a group-wide basis using foreign exchange forward and option contracts as well as cross-currency swaps.

We also make use of economic hedges. All derivatives that qualify for hedge accounting have been cash-flow hedges. Further details of our derivative and hedging activities can be found in Note 7 to the accompanying condensed consolidated financial statements.

Recent Authoritative Pronouncements

For information on recent accounting pronouncements impacting our business, see Note 2 to the accompanying condensed consolidated financial statements.

Application of Critical Accounting Policies, Judgments and Estimates

The preparation of our financial statements in accordance with accounting principles generally accepted in the United States requires management to make assumptions that affect the reported amounts of assets and liabilities and disclosure of contingencies as of the date of the financial statements, as well as the reported amounts of revenues and expenses during the reporting period. Critical accounting policies are those that require the most complex or subjective judgments, often as a result of the need to make estimates about the effects of matters that are inherently uncertain. Thus, to the extent that actual events differ from management’s estimates and assumptions, there could be a material impact on the financial statements. In applying our critical accounting policies, at times we used accounting estimates that either required us to make assumptions about matters that were highly uncertain at the time the estimate was made or were reasonably likely to change from period to period, having a material impact on the presentation of our results of operations, financial position or cash flows. Our critical accounting policies are those related to revenue recognition, share-based compensation, income taxes, investments, variable interest entities, goodwill and other intangible assets, purchase price allocation and fair value measurements.

Our critical accounting policies are discussed further in Item 5 of our Annual Report on Form 20-F for the year ended December 31, 2013. Actual results in these areas could differ from management’s estimates. There have been no significant changes in our critical accounting policies during 2014.

Off-Balance Sheet Arrangements

Other than our arrangements with QIAGEN Finance and Euro Finance as discussed above and in Notes 9 and 16 to the accompanying condensed consolidated financial statements, we did not use special purpose entities and did not have off-balance-sheet financing arrangements as of March 31, 2014 and December 31, 2013.

Contractual Obligations

There were no material changes at March 31, 2014 from the contractual obligations disclosed in Item 5 of our Annual Report on Form 20-F for the year ended December 31, 2013 other than the issuance of the Cash Convertible Notes as described in Note 9 in the accompanying Notes to Consolidated Financial Statements.

Legal Proceedings

For information on legal proceedings, see Note 14 to the accompanying condensed consolidated financial statements.

While no assurances can be given regarding the outcome of the proceedings described in Note 14, based on information currently available, we believe that the resolution of these matters is unlikely to have a material adverse effect on our financial position or results of future operations for QIAGEN N.V. as a whole. However, because of the nature and inherent uncertainties of litigation, should the outcomes be unfavorable, certain aspects of our business, financial condition, and results of operations and cash flows could be materially adversely affected.

Risk Factors

Material risks that may affect our results of operations and financial position appear in Part 1, Item 3 "Key Information" of the 2013 Annual Report on Form 20-F for the year ended December 31, 2013. There have been no material changes from the risk factors disclosed in Item 3 of our Form 20-F other than those described below.

The accounting for the Cash Convertible Notes will result in our having to recognize interest expense significantly greater than the stated interest rate of the notes and may result in volatility to our Consolidated Statements of Operations.

We will settle any conversions of the Cash Convertible Notes entirely in cash. Accordingly, the conversion option that is part of the Cash Convertible Notes will be accounted for as a derivative pursuant to accounting standards relating to derivative instruments and

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hedging activities. Refer to Note 7, “Derivatives,” of the Notes to Consolidated Financial Statements in. In general, this resulted in an initial valuation of the conversion option separate from the debt component of the Cash Convertible Notes, resulting in an original issue discount. The original issue discount will be accreted to interest expense over the term of the Cash Convertible Notes, which will result in an effective interest rate reported in our financial statements significantly in excess of the stated coupon rates of the Cash Convertible Notes. This accounting treatment will reduce our earnings. For each financial statement period after the issuance of the Cash Convertible Notes, a hedge gain (or loss) will be reported in our financial statements to the extent the valuation of the conversion option changes from the previous period. The Call Options will also be accounted for as derivative instruments, substantially offsetting the gain (or loss) associated with changes to the valuation of the conversion option. This may result in increased volatility to our results of operations.

The cash convertible note hedge and warrant transactions we entered into in connection with the issuance of our Cash Convertible Notes may not provide the benefits we anticipate, and may have a dilutive effect on our common stock.

Concurrently with the issuance of the Cash Convertible Notes, we entered into Call Options with, and issued Warrants. We entered into the Call Options with the expectation that they would offset potential cash payments by us in excess of the principal amount of the Cash Convertible Notes upon conversion of the Cash Convertible Notes. In the event that the hedge counterparties fail to deliver potential cash payments to us, as required under the Call Options, we would not receive the benefit of such transaction. Separately, we also issued Warrants. The Warrants could separately have a dilutive effect to the extent that the market price per share of our common stock, as measured under the terms of the Warrants, exceeds the strike price of the Warrants.

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