Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
GREEN DAVID
   2. Issuer Name and Ticker or Trading Symbol
HARVARD BIOSCIENCE INC [HBIO] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
84 OCTOBER HILL ROAD		 3. Date of Earliest Transaction (Month/Day/Year)
11/01/2013
(Street)

HOLLISTON, MA 01746		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 11/01/2013   J   53,372 (1) A $ 0 1,711,881 (2) D  
Common Stock               300,000 I David Green 2013 Annuity Trust

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock option (right to buy) $ 5.73 11/01/2013   J   71,515 (1)     (3) 03/25/2014 Common Stock, par value $0.01 per share 71,515 $ 0 271,515 (1) D  
Stock option (right to buy) $ 3.99 11/01/2013   J   63,447 (1)     (4) 05/01/2017 Common Stock, par value $0.01 per share 63,447 $ 0 263,447 (1) D  
Stock option (right to buy) $ 1.43 11/01/2013   J   23,894 (1)     (5) 12/04/2018 Common Stock, par value $0.01 per share 23,894 $ 0 98,894 (1) D  
Stock option (right to buy) $ 2.28 11/01/2013   J   127,115 (1)     (6) 05/21/2019 Common Stock, par value $0.01 per share 127,115 $ 0 527,115 (1) D  
Stock option (right to buy) $ 4.04 11/01/2013   J   34,082 (1)     (7) 06/02/2021 Common Stock, par value $0.01 per share 34,082 $ 0 141,582 (1) D  
Stock option (right to buy) $ 2.56 11/01/2013   J   53,959 (1)     (8) 06/01/2022 Common Stock, par value $0.01 per share 53,959 $ 0 223,888 (1) D  
Stock option (right to buy) $ 3.64 11/01/2013   J   25,383 (1)     (9) 05/31/2023 Common Stock, par value $0.01 per share 25,383 $ 0 105,411 (1) D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
GREEN DAVID
84 OCTOBER HILL ROAD
HOLLISTON, MA 01746		   X      

Signatures

 David Green   11/05/2013
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) These additional options and restricted stock units were acquired by the Reporting Person in connection with the adjustment to the existing options and restricted stock units held by the Reporting Person and required in connection with the spin-off of Harvard Apparatus Regenerative Technology, Inc. by the Issuer. As part of such required adjustment relating to the spin-off, the exercise price of the options underlying these adjustment option grants was also reset to the exercise price of these adjustment grants to reflect the impact of the spin-off. The share amounts and exercise prices of the adjusted options and restricted stock units were set in a manner to ensure the intrinsic value held by the Reporting Person pertaining to the existing award was maintained immediately following the spin-off. In addition to these adjustments, to maintain such intrinsic value, equity awards issued by Harvard Apparatus Regenerative Technology, Inc. were also granted to the Reporting Person.
(2) Includes (a) an adjusted deferred stock award of 43,985 restricted stock units which shall vest on Jan 1, 2014; (b) an adjusted deferred stock award of 35,394 restricted stock units which vest in equal installments on Jan 1, 2014 and Jan 1, 2015; (c) an adjusted deferred stock award of 87,645 restricted stock units which vest in equal installments on Jan 1, 2014, Jan 1, 2015, and Jan 1, 2016; (d) an adjusted deferred stock award of 54,750 restricted stock units which vest in equal installments on Jan 1, 2014, Jan 1, 2015, Jan 1, 2016, and Jan 1, 2017; and (e) 1,490,107 shares of common stock held by the Reporting Person.
(3) The option shares vested in four equal installments on January 1, 2005, 2006, 2007 and 2008.
(4) The option shares vested in four equal installments on January 1, 2008, 2009, 2010 and 2011.
(5) The option shares vested in four equal installments on January 1, 2009, 2010, 2011 and 2012.
(6) The option shares vested in four equal installments on January 1, 2010, 2011, 2012 and 2013
(7) The unvested shares become exercisable in equal installments on January 1 of each of 2014 and 2015.
(8) The unvested shares become exercisable in equal installments on January 1 of each of 2014, 2015 and 2016.
(9) The unvested shares become exercisable in equal installments on January 1 of each of 2014, 2015, 2016 and 2017.
 
Remarks:
This form has been signed under power of attorney.

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