1. Title of Derivative Security (Instr. 4) |
2. Date Exercisable and Expiration Date (Month/Day/Year) |
3. Title and Amount of Securities Underlying Derivative Security (Instr. 4) |
4. Conversion or Exercise Price of Derivative Security |
5. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 5) |
6. Nature of Indirect Beneficial Ownership (Instr. 5) |
Date Exercisable |
Expiration Date |
Title |
Amount or Number of Shares |
B-2 Investor Warrants
|
04/04/2005 |
08/04/2009 |
Common Stock
|
125,000
|
$
1
|
I
|
By ISIS Acquisition Partners II LLC
|
B-2 Investor Warrants
|
04/04/2005 |
09/30/2009 |
Common Stock
|
250,000
|
$
1
|
I
|
By ISIS Acquisition Partners II LLC
|
Series C Investor Warrants
|
Â
(1)
|
03/31/2010 |
Common Stock
|
287,795
|
$
1.25
|
I
|
By ISIS Acquisition Partners II LLC
|
Series C Investor Warrants
|
Â
(1)
|
03/31/2005 |
Common Stock
|
240,553
|
$
1.25
|
I
|
By ISIS Acquisition Partners LLC
|
Series C Investor Warrants
|
Â
(1)
|
03/31/2005 |
Common Stock
|
1,284,913
|
$
1.25
|
I
|
By ISIS Capital Management, LLC
|
Options
|
Â
(2)
|
08/04/2014 |
Common Stock
|
150,686
|
$
6.75
|
D
|
Â
|
Options
|
Â
(2)
|
08/04/2014 |
Common Stock
|
200,914
|
$
6.75
|
I
|
By ISIS Capital Management, LLC
|
Series C Preferred Stock
|
Â
(1)
|
03/31/2008 |
Common Stock
|
287,795
|
$
1
|
I
|
By ISIS Acquisition Partners II LLC
|
Series C Preferred Stock
|
Â
(1)
|
03/31/2008 |
Common Stock
|
240,553
|
$
1
|
I
|
By ISIS Acquisition Partners LLC
|
Series C Preferred Stock
|
Â
(1)
|
03/31/2008 |
Common Stock
|
1,284,913
|
$
1
|
I
|
By ISIS Capital Management LLC
|