Ownership Submission
FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Sweeney Edward J
 2. Date of Event Requiring Statement (Month/Day/Year)
10/29/2008		 3. Issuer Name and Ticker or Trading Symbol
ENDO PHARMACEUTICALS HOLDINGS INC [ENDP]
(Last)
(First)
(Middle)
C/O ENDO PHARMACEUTICALS HOLDINGS INC., 100 ENDO BOULEVARD		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Principal Accounting Officer
 5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

CHADDS FORD, PA 19317		 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
2007 Stock Incentive Plan Restricted Stock Units (RSUs) (1) 2,084
D
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
2000 Stock Incentive Plan Options   (2) 08/11/2014 Common Stock 1,292 $ 16.47 D  
2004 Stock Incentive Plan Options   (3) 02/14/2016 Common Stock 6,339 $ 28.61 D  
2000 Stock Incentive Plan Options   (4) 02/21/2017 Common Stock 4,612 $ 30.55 D  
2007 Stock Incentive Plan Options   (5) 02/21/2018 Common Stock 6,757 $ 25.19 D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Sweeney Edward J
C/O ENDO PHARMACEUTICALS HOLDINGS INC.
100 ENDO BOULEVARD
CHADDS FORD, PA 19317		       Principal Accounting Officer  

Signatures

/s/ Edward J. Sweeney 02/26/2009
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) These restricted stock units (RSUs) vest over a three-year period, 25% on February 21, 2010, 25% February 21, 2011 and 25% on February 21, 2012.
(2) Exercisable 50% per year on each of August 11, 2007 and August 11, 2008.
(3) Exercisable 25% per year on each of February 14, 2007, February 21, 2008, February 21, 2009 and February 21, 2010.
(4) Exercisable 25% per year on each of February 21, 2008, February 21, 2009, February 21, 2010 and February 21, 2011.
(5) Exercisable 25% per year on each of February 21, 2009, February 21, 2010, February 21, 2011 and February 21, 2012.

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