Ownership Submission
FORM 3
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Hove Anders D
2. Date of Event Requiring Statement (Month/Day/Year)
02/16/2017
3. Issuer Name and Ticker or Trading Symbol
ARCA biopharma, Inc. [ABIO]
(Last)
(First)
(Middle)
11080 CIRCLEPOINT RD., SUITE 140
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

WESTMINSTER, CO 80023
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 767,660
I
By Venrock Healthcare Capital Partners II, L.P. (1)
Common Stock 311,272
I
By VHCP Co-Investment Holdings II, LLC (2)
Common Stock 390,912
I
By Venrock Healthcare Capital Partners, L.P. (3)
Common Stock 71,487
I
By VHCP Co-Investment Holdings, LLC (4)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(Month/Day/Year)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Common stock warrants (right to buy) 12/13/2015 06/16/2022 Common Stock 307,064 $ 6.1012 I By Venrock Healthcare Capital Partners II, L.P. (1)
Common stock warrants (right to buy) 12/13/2015 06/16/2022 Common Stock 124,508 $ 6.1012 I By VHCP Co-Investment Holdings II, LLC (2)
Common stock warrants (right to buy) 12/13/2015 06/16/2022 Common Stock 156,365 $ 6.1012 I By Venrock Healthcare Capital Partners, L.P. (3)
Common stock warrants (right to buy) 12/13/2015 06/16/2022 Common Stock 28,594 $ 6.1012 I By VHCP Co-Investment Holdings, LLC (4)

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Hove Anders D
11080 CIRCLEPOINT RD., SUITE 140
WESTMINSTER, CO 80023
  X      

Signatures

/s/ Brian L. Selby, Attorney-in-Fact 02/21/2017
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) These securities are owned directly by Venrock Healthcare Capital Partners II, L.P. The Reporting Person has a pecuniary interest in Venrock Healthcare Capital Partners II, L.P. The Reporting Person holds no voting or investment interest in these securities, and disclaims beneficial ownership of such shares except to the extent of his pro rata partnership interest therein.
(2) These securities are owned directly by VHCP Co-Investment Holdings II, LLC. The Reporting Person has a pecuniary interest in VHCP Co-Investment Holdings II, LLC. The Reporting Person holds no voting or investment interest in these securities, and disclaims beneficial ownership of such shares except to the extent of his pro rata partnership interest therein.
(3) These securities are owned directly by Venrock Healthcare Capital Partners, L.P. The Reporting Person has a pecuniary interest in Venrock Healthcare Capital Partners, L.P. The Reporting Person holds no voting or investment interest in these securities, and disclaims beneficial ownership of such shares except to the extent of his pro rata partnership interest therein.
(4) These securities are owned directly by VHCP Co-Investment Holdings, LLC. The Reporting Person has a pecuniary interest in VHCP Co-Investment Holdings, LLC. The Reporting Person holds no voting or investment interest in these securities, and disclaims beneficial ownership of such shares except to the extent of his pro rata partnership interest therein.
 
Remarks:
Exhibit 24- Power of Attorney

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