Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
HAGELSTEIN DAVID A
  2. Issuer Name and Ticker or Trading Symbol
ROCKWELL MEDICAL, INC. [RMTI]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
36801 WOODWARD AVE, STE 313
3. Date of Earliest Transaction (Month/Day/Year)
11/26/2012
(Street)

BIRMINGHAM, MI 48009
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock               1,372,430 (1) D  
Common Stock               438,822 (1) I By self as trustee of the David Hagelstein Charitable Remainder Unitrust

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Common Stock Warrant $ 7.18 11/26/2012   D(2)     862,502   (2) 11/28/2012 Common Stock 862,502 (2) 0 D  
Common Stock Warrant $ 7.18 11/26/2012   A(2)   862,502     (2) 01/28/2013 Common Stock 862,502 (2) 862,502 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
HAGELSTEIN DAVID A
36801 WOODWARD AVE
STE 313
BIRMINGHAM, MI 48009
    X    

Signatures

 Fred B. Green as attorney-in-fact   11/28/2012
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Pursuant to its terms, the David Hagelstein Charitable Remainder Unitrust made a distribution at the end of the third quarter of 2012 of 11,730 shares of common stock of Rockwell to the David Hagelstein Revocable Living Trust. The distribution is an exempt transaction pursuant to Rule 16a-13 under the Securities Exchange Act of 1934.
(2) Issuer originally issued Common Stock Warrants to purchase 862,502 shares of Issuer's common stock on November 28, 2007 at an exercise price of $7.18 per share. Such Warrants became exercisable on November 28, 2008. The David Hagelstein Revocable Living Trust acquired these Warrants to purchase the 862,502 shares of Issuer's common stock through acquisitions on October 22, 2010 (with respect to 400,000 shares), November 23, 2010 (with respect to 313,000 shares, March 1, 2011 (with respect to 53,668 shares), May 4, 2011 (with respect to 25,000 shares) and November 21, 2011 (with respect to 70,834 shares). On November 26, 2012, Issuer amended the Warrants acquired by the David Hagelstein Revocable Living Trust by extending the expiration date of the Warrants from November 28, 2012 to January 28, 2013. The amendment results in the deemed cancellation of the 'old' Warrants and the grant of replacement Warrants.

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