As filed with the Securities and Exchange Commission on April 16, 2001

                                                      Registration No. 333-04555
================================================================================


                     U.S. SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                             ----------------------

                         POST-EFFECTIVE AMENDMENT NO. 1
                                       TO
                                    FORM S-8
                             REGISTRATION STATEMENT
                        UNDER THE SECURITIES ACT OF 1933

                             ----------------------

                            APPLIED BIOMETRICS, INC.
             (Exact name of registrant as specified in its charter)

                      MINNESOTA                            41-1508112
           (State or other jurisdiction of               (I.R.S. Employer
           incorporation or organization)              Identification No.)

                   P.O. BOX 3170
                BURNSVILLE, MN 55337                          55337
      (Address of Principal Executive Offices)             (Zip Code)

                             ----------------------

                            APPLIED BIOMETRICS, INC.
                             1987 STOCK OPTION PLAN
                                       AND
                                 1996 STOCK PLAN
                            (Full title of the plans)

                             ----------------------

                               JAMES D. BONNEVILLE
                         ACTING CHIEF EXECUTIVE OFFICER
                                  P.O. BOX 3170
                              BURNSVILLE, MN 55337
                                 (612) 338-4722
                      (Name, address and telephone number,
                   including area code, of agent for service)

                             ----------------------



                                   Copies to:

                             Kimberly A. Lowe, Esq.
                        Oppenheimer Wolff & Donnelly LLP
                     3300 Plaza VII, 45 South Seventh Street
                          Minneapolis, Minnesota 55402
                                 (612) 607-7000




                         POST-EFFECTIVE AMENDMENT NO. 1

         The purpose of this Post-Effective Amendment No. 1 to Form S-8,
Registration Statement No. 333-04555 for the Applied Biometrics, Inc. 1987 Stock
Option Plan and 1996 Stock Plan, is to deregister shares registered for issuance
pursuant to the Applied Biometrics, Inc. 1987 Stock Option Plan and 1996 Stock
Plan. The Form S-8 registered 356,389 shares for issuance under the Applied
Biometrics Inc. 1987 Stock Option Plan and 1996 Stock Option Plan. Applied
Biometrics, Inc. hereby removes from registration the securities of Applied
Biometrics, Inc. registered but unsold under Registration Statement No.
333-04555.

         As there are no securities being registered in this amendment, the sole
purpose of the amendment is to deregister securities, the disclosure
requirements under the Securities Act of 1933 and the requirement for exhibits
under Regulation S-K are inapplicable to this filing.




                                   SIGNATURES

              Pursuant to the requirements of the Securities Act of 1933, the
registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements of filing on Form S-8 and has duly caused this
Post-Effective Amendment No. 1 to the Registration Statement to be signed on its
behalf by the undersigned, thereunto duly authorized, in the City of
Minneapolis, State of Minnesota, on April 16, 2001.

                                        APPLIED BIOMETRICS, INC.


                                        By: /s/ James D. Bonneville
                                            ------------------------------------
                                            James D. Bonneville
                                            Acting Chief Executive Officer


              Pursuant to the requirements of the Securities Act of 1933, this
Post-Effective Amendment No. 1 to the Registration Statement has been signed on
April 16, 2001 by the following persons in the capacities indicated.

                SIGNATURE                                TITLE
                ---------                                -----

/s/ James D. Bonneville                Acting Chief Executive Officer (principal
------------------------------------   executive officer and principal financial
 James D. Bonneville                   officer)


/s/ Andrew Weiss                       Chairman of the Board and Director
------------------------------------
Andrew Weiss

/s/ Jeffrey Green                      Director
------------------------------------
Jeffrey Green