California
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94-3127919
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(State or other jurisdiction of incorporation or organization)
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(I.R.S. Employer Identification No.)
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Title of each class
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Name of exchange on which registered
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Common shares, no par value
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NYSE MKT
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Common share purchase warrants expiring October 1, 2018
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NYSE MKT
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Large accelerated filer ☐
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Accelerated filer ☒
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Non-accelerated filer ☐ (Do not check if a smaller reporting company)
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Smaller reporting company ☐
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Item 15.
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Exhibits, Financial Statement Schedules
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(a-1) | Financial Statements. |
(a-2) | Financial Statement Schedules |
(a-3) | Exhibits. |
Exhibit
Numbers
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Description
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2.1
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Asset Contribution Agreement, dated January 4, 2013, by and among BioTime, Inc., BioTime Acquisition Corporation, and Geron Corporation. Schedules to the Asset Contribution Agreement have been omitted. BioTime agrees to furnish supplementally a copy of the omitted schedules to the Commission upon request. (1)
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3.1
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Articles of Incorporation with all amendments (2)
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3.2
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By-Laws, As Amended (3)
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4.1
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Specimen of Common Share Certificate (4)
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4.2
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Form of Warrant Issued June 2013 (5)
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4.3
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Warrant Agreement, dated as of October 1, 2013, as amended September 19, 2014, between BioTime, Inc. and American Stock Transfer & Trust Company, LLC as Warrant Agent for the benefit of Asterias Biotherapeutics, Inc. (6)
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4.4
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Warrant Issued October 1, 2013 to Asterias Biotherapeutics, Inc. (included in Exhibit 4.7) (6)
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10.1
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Intellectual Property Agreement between BioTime, Inc. and Hal Sternberg (4)
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10.2
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Intellectual Property Agreement between BioTime, Inc. and Judith Segall (4)
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10.3
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2002 Stock Option Plan, as amended (7)
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10.4
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Exclusive License Agreement between Abbott Laboratories and BioTime, Inc. (Portions of this exhibit have been omitted pursuant to a request for confidential treatment) (8)
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10.5
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Modification of Exclusive License Agreement between Abbott Laboratories and BioTime, Inc. (Portions of this exhibit have been omitted pursuant to a request for confidential treatment) (9)
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10.6
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Exclusive License Agreement between BioTime, Inc. and CJ Corp. (10)
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10.7
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Amendment to Exclusive License Agreement Between BioTime, Inc. and Hospira, Inc. (11)
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10.8
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Employment Agreement, dated October 10, 2007, between BioTime, Inc. and Michael D. West. (12)
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10.9
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Commercial License and Option Agreement between BioTime and Wisconsin Alumni Research Foundation (13)
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10.10
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License Agreement, dated July 10, 2008, between Embryome Sciences, Inc. and Advanced Cell Technology, Inc. (14)
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10.11
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First Amendment of Commercial License and Option Agreement, dated March 11, 2009, between BioTime and Wisconsin Alumni Research Foundation (15)
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10.12
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Registration Rights Agreement between OncoCyte Corporation and George Karfunkel (16)
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10.13
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Amended and Restated Shareholders Agreement, dated October 7, 2010, by and among ES Cell International Pte. Ltd, BioTime, Inc., Teva Pharmaceutical Industries, Limited, HBL-Hadasit Bio-Holdings, Ltd., and Cell Cure Neurosciences Ltd. (17)
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10.14
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Amended and Restated Research and License Agreement, dated October 7, 2010, between Hadasit Medical Research Services and Development Ltd. and Cell Cure Neurosciences Ltd. (17)
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10.15
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Additional Research Agreement, dated October 7, 2010, between Hadasit Medical Research Services and Development Ltd. and Cell Cure Neurosciences Ltd. (17)
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10.16
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Exclusive License Agreement, dated November 20, 2007, between Cell Targeting, Inc. and Burnham Institute for Medical Research (17)
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10.17
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OncoCyte Corporation 2010 Stock Option Plan; Form of OncoCyte Corporation Stock Option Agreement (17)
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10.18
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OrthoCyte Corporation 2010 Stock Option Plan; Form of OrthoCyte Corporation Stock Option Agreement (17)
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10.19
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BioTime Asia, Limited 2010 Stock Option Plan; Form of BioTime Asia Limited Stock Option Agreement (17)
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10.20
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License Agreement between BioTime, Inc. and Cornell University (Portions of this exhibit have been omitted pursuant to a request for confidential treatment) (18)
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10.21
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LifeMap, Inc. 2011 Stock Option Plan; and Form of LifeMap, Inc. Stock Option Agreement (19)
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10.22
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Exclusive License Agreement, dated February 15, 2006, between Glycosan BioSystems, Inc. and the University of Utah Research Foundation, as amended (20)
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10.23
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Option Agreement, dated June 3, 2013, between BioTime, Inc. and certain investors (21)
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10.24
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Client Referral and Solicitation Agreement, dated April 1, 2013, between BioTime, Inc., LifeMap Sciences, Inc. and OBEX Securities, LLC (5)
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10.25
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Royalty Agreement, dated October 1, 2013, between Asterias Biotherapeutics, Inc. and Geron Corporation (22)
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10.26
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Exclusive Sublicense Agreement, dated October 1, 2013, between Geron Corporation and Asterias Biotherapeutics, Inc. (22)
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10.27
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Exclusive License Agreement, dated February 20, 2003, and First Amendment thereto dated September 7, 2004, between The Regents of the University of California and Geron Corporation (22)
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10.28
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Non-Exclusive License Agreement, dated as of October 7, 2013, between the Wisconsin Alumni Research Foundation and Asterias Biotherapeutics, Inc. (Portions of this exhibit have been omitted pursuant to a request for confidential treatment) (22)
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10.29
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Equity Incentive Plan (22)
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10.30
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Form of Employee Incentive Stock Option Agreement (22)
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10.31
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Form of Non-employee Director Stock Option Agreement (22)
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10.32
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Asterias Biotherapeutics, Inc. Equity Incentive Plan (23)
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10.33
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Form of Asterias Biotherapeutics, Inc. Employee Incentive Stock Option Agreement (24)
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10.34
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Form of Asterias Biotherapeutics, Inc. Non-employee Director Stock Option Agreement (24)
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10.35
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Lease, dated December 30, 2013, by and between BMR 6300 Dumbarton Circle, LP, and Asterias Biotherapeutics, Inc. (25)
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10.36
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Option Agreement, dated March 4, 2014, between BioTime and certain investors (25)
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10.37
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Co-Development and Option Agreement, dated May 6, 2014, between LifeMap Solutions, Inc. and the Icahn School of Medicine at Mount Sinai (Portions of this exhibit have been omitted pursuant to a request for confidential treatment) (26)
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10.38
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Stock Purchase Agreement, dated May 6, 2014, between LifeMap Sciences, Inc. and BioTime, Inc. (Portions of this exhibit have been omitted pursuant to a request for confidential treatment) (26)
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10.39
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Stock Purchase Agreement, dated June 12, 2014, between Pedro Lichtinger and Asterias Biotherapeutics, Inc. (26)
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10.40
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Purchase Agreement, dated June 13, 2014, between Broadwood Partners, L.P. and Asterias Biotherapeutics, Inc. (26)
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10.41
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Purchase Agreement, dated June 13, 2014, between The George Karfunkel 2007 Grantor Trust #1 and Asterias Biotherapeutics, Inc. (26)
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10.42
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Registration Rights Agreement, dated June 16, 2014, between The George Karfunkel 2007 Grantor Trust #1, Broadwood Partners, L.P., and Asterias Biotherapeutics, Inc. (26)
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10.43
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Employment Agreement, dated as of June 9, 2014, between Pedro Lichtinger and Asterias Biotherapeutics, Inc. (26)
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10.44
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LifeMap Solutions, Inc. 2014 Stock Option Plan (26)
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10.45
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Form of LifeMap Solutions, Inc. Incentive Stock Option Agreement (26)
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10.46
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Form of LifeMap Solutions, Inc. Stock Option Agreement (26)
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10.47
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Clinical Trial and Option Agreement, dated September 8, 2014, between Asterias Biotherapeutics, Inc. and Cancer Research UK and Cancer Research Technology Limited(Portions of this exhibit have been omitted pursuant to a request for confidential treatment) (27)
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10.48
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Notice of Grant Award, dated as of October 16, 2014, between the California Institute for Regenerative Medicine and Asterias Biotherapeutics, Inc. (Portions of this exhibit have been omitted pursuant to a request for confidential treatment) (28)
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10.49
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Amendment to Notice of Grant Award, dated as of November 26, 2014, between the California Institute for Regenerative Medicine and Asterias Biotherapeutics, Inc. (Portions of this exhibit have been omitted pursuant to a request for confidential treatment) (28)
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10.50
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Consulting Agreement, dated December 15, 2014, between BioTime, Inc. and William P. Tew (28)
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10.51
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Employment Agreement, dated December 29, 2014, between BioTime, Inc. Aditya Mohanty (28)
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10.52
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Subscription Agreements between Asterias Biotherapeutics, Inc. and the investors named therein (28)
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10.53
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First Amendment to Co-Development and Option Agreement, dated March 7, 2015, between Icahn School of Medicine at Mount Sinai and LifeMap Solutions, Inc. (Portions of this exhibit have been omitted pursuant to a request for confidential treatment) (29)
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10.54
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2012 Equity Incentive Plan, as amended (30)
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10.55
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Stock Purchase Agreements, dated September 14, 2015, between BioTime, Inc. and certain investors (31)
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10.56
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Research & Development Agreement, dated September 29, 2015, between OrthoCyte Corporation and Heraeus Medical GmbH (Portions of this exhibit have been omitted pursuant to a request for confidential treatment) (31)
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10.57
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License Agreement, dated September 29, 2015, between OrthoCyte Corporation and Heraeus Medical GmbH (Portions of this exhibit have been omitted pursuant to a request for confidential treatment) (31)
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10.58
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Stock Purchase Agreements Between BioTime and certain investors (31)
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10.59
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Subscription Agreement, dated September 29, 2015, between OncoCyte Corporation and BioTime, Inc. (31)
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10.60
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Letter Agreement, dated September 24, 2015, between BioTime, Inc. and Union Underwriting & Finances Ltd. (32)
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10.61
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Employment Agreement, dated November 16, 2015, between BioTime, Inc. and Russell Skibsted (33)
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10.62
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Employment Termination and Release Agreement, dated November 18, 2015, between BioTime, Inc. and Robert W. Peabody (34)
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10.63
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Employment Agreement, dated November 18, 2015, between LifeMap Solutions, Inc. and Robert W. Peabody (34)
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10.64
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Consulting Agreement, dated November 18, 2015, between BioTime, Inc. and Robert W. Peabody (34)
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10.65
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Amendment of Employment Agreement, dated November 24, 2015, between BioTime, Inc. and Michael D. West (35)
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10.66
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Amendment of Employment Agreement, dated November 24, 2015, between BioTime, Inc. and Aditya Mohanty (35)
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10.67
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Lease, dated December 10, 2015, between BioTime, Inc. and BSREP Marina Village Owner LLC (36)
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License Agreement, dated January 22, 2016, between OncoCyte Corporation and The Wistar Institute of Anatomy and Biology (Portions of this exhibit have been omitted pursuant to a request for confidential treatment) *
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||
10.69
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First Amendment to License Agreement, dated January 25, 2016, between OncoCyte Corporation and The Wistar Institute of Anatomy and Biology (37)
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21.1
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List of Subsidiaries (37)
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23.1
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Consent of OUM & Co. LLP (37)
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23.2
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Consent of Rothstein Kass (37)
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Rule 13a-14(a)/15d-14(a) Certification *
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||
32
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Section 1350 Certification (37)
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101
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Interactive Data File
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101.INS
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XBRL Instance Document (37)
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101.SCH
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XBRL Taxonomy Extension Schema (37)
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101.CAL
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XBRL Taxonomy Extension Calculation Linkbase (37)
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101.LAB
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XBRL Taxonomy Extension Label Linkbase(37)
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101.PRE
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XBRL Taxonomy Extension Presentation Linkbase(37)
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101.DEF
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XBRL Taxonomy Extension Definition Document(37)
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(1)
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Incorporated by reference to BioTime’s Current Report on Form 8-K filed with the Securities and Exchange Commission on January 8, 2013
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(2)
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Incorporated by reference to BioTime’s Annual Report on Form 10-K/A-1 for the year ended December 31, 2013
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(3)
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Incorporated by reference to Registration Statement on Form S-1, File Number 33-48717 and Post-Effective Amendment No. 1 thereto filed with the Securities and Exchange Commission on June 22, 1992, and August 27, 1992, respectively
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(4)
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Incorporated by reference to Registration Statement on Form S-1, File Number 33-44549 filed with the Securities and Exchange Commission on December 18, 1991, and Amendment No. 1 and Amendment No. 2 thereto filed with the Securities and Exchange Commission on February 6, 1992 and March 7, 1992, respectively
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(5)
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Incorporated by reference to BioTime’s Current Report on Form 8-K filed with the Securities and Exchange Commission on June 3, 2013
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(6)
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Incorporated by reference to BioTime’s Current Report on Form 8-K filed with the Securities and Exchange Commission on September 23, 2014
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(7)
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Incorporated by reference to BioTime’s Quarterly Report on Form 10-Q for the quarter ended June 30, 2009
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(8)
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Incorporated by reference to BioTime’s Current Report on Form 8-K, filed April 24, 1997
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(9)
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Incorporated by reference to BioTime’s Form Quarterly Report on 10-Q for the quarter ended June 30, 1999
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(10)
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Incorporated by reference to BioTime’s Annual Report on Form 10-K/A-1 for the year ended December 31, 2002
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(11)
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Incorporated by reference to BioTime’s Current Report on Form 8-K, filed January 13, 2006
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(12)
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Incorporated by reference to BioTime’s Annual Report on Form 10-KSB for the year ended December 31, 2007
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(13)
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Incorporated by reference to BioTime’s Current Report on Form 8-K, filed January 9, 2008
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(14)
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Incorporated by reference to BioTime’s Quarterly Report on Form 10-Q for the quarter ended June 30, 2008
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(15)
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Incorporated by reference to BioTime’s Annual Report on Form 10-K for the year ended December 31, 2008
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(16)
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Incorporated by reference to BioTime’s Quarterly Report on Form 10-Q for the quarter ended September 30, 2009
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(17)
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Incorporated by reference to BioTime’s Annual Report on Form 10-K for the year ended December 31, 2010
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(18)
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Incorporated by reference to BioTime’s Quarterly Report on Form 10-Q for the quarter ended September 30, 2011
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(19)
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Incorporated by reference to BioTime’s Annual Report on Form 10-K for the year ended December 31, 2011
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(20)
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Incorporated by reference to BioTime’s Quarterly Report on Form 10-Q for the quarter ended September 30, 2012
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(21)
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Incorporated by reference to BioTime’s Quarterly Report on Form 10-Q for the quarter ended June 30, 2013
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(22)
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Incorporated by reference to BioTime’s Quarterly Report on Form 10-Q for the quarter ended September 30, 2013
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(23)
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Incorporated by reference to Amendment No. 1 to Registration Statement on Form S-1 (333-187706) filed by Asterias Biotherapeutics, Inc. with the Securities and Exchange Commission on June 26, 2013
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(24)
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Incorporated by reference to Amendment No. 2 to Registration Statement on Form S-1 (333-187706) filed by Asterias Biotherapeutics, Inc. with the Securities and Exchange Commission on August 13, 2013
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(25)
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Incorporated by reference to BioTime’s Annual Report on Form 10-K for the year ended December 31, 2013
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(26)
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Incorporated by reference to BioTime’s Quarterly Report on Form 10-Q for the quarter ended June 30, 2014
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(27)
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Incorporated by reference to BioTime’s Quarterly Report on Form 10-Q/A-1 for the quarter ended September 30, 2014
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(28)
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Incorporated by reference to BioTime’s Annual Report on Form 10-K for the year ended December 31, 2014
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(29)
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Incorporated by reference to BioTime’s Quarterly Report on Form 10/Q for the quarter ended March 31, 2015
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(30)
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Incorporated by reference to Registration Statement on Form S-1, File Number 333-205661 filed with the Securities and Exchange Commission on July 15, 2015
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(31)
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Incorporated by reference to BioTime’s Quarterly Report on Form 10/Q for the quarter ended September 30, 2015
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(32)
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Incorporated by reference to Current Report on Form 8-K filed with the Securities and Exchange Commission on September 25, 2015
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(33)
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Incorporated by reference to BioTime’s Current Report on Form 8-K, filed November 16, 2015
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(34)
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Incorporated by reference to BioTime’s Current Report on Form 8-K, filed November 18, 2015
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(35)
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Incorporated by reference to BioTime’s Current Report on Form 8-K, filed November 24, 2015
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(36)
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Incorporated by reference to BioTime’s Current Report on Form 8-K, filed December 9, 2015
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(37)
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Previously filed with BioTime’s Annual Report on Form 10-K for the year ended December 31, 2015, filed March 15, 2016
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*
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Filed herewith
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BIOTIME, INC.
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By:
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/s/Michael D. West
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Michael D. West, Ph.D.
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Co-Chief Executive Officer
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By:
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/s/Aditya Mohanty
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Aditya Mohanty
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Co-Chief Executive Officer
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