Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
Margolis Jeff Eliot
  2. Issuer Name and Ticker or Trading Symbol
RespireRx Pharmaceuticals Inc. [RSPI]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
VP, Treasurer & Secretary
(Last)
(First)
(Middle)
C/O RESPIRERX PHARMACEUTCALS INC., 126 VALLEY ROAD, SUITE C
3. Date of Earliest Transaction (Month/Day/Year)
08/28/2015
(Street)

GLEN ROCK, NJ 07452
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 09/14/2015   X   507,374 A (1) 15,618,816 D  
Common Stock 09/14/2015   S(1)   483,872 D (1) 15,134,944 D  

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Warrants (right to buy) $ 0.021 08/28/2015   J(2)   325,022     (2) 09/30/2020 Common Stock 325,022 $ 0 325,022 D (4)  
Warrants (right to buy) $ 0.035 09/14/2015   X     507,374   (1) 09/15/2015 Common Stock 507,374 (1) 0 D  
Warrants (right to buy) $ 0.021 09/28/2015   J(2)   309,975     (2) 09/30/2020 Common Stock 309,975 $ 0 634,997 D (4)  
Warrants (right to buy) $ 0.021 11/02/2015   J(2)   939,729     (2) 09/30/2020 Common Stock 939,729 $ 0 1,574,726 D (4)  
Common Stock Options (to purchase shares of Common Stock) $ 0.0227 03/31/2016   A   24,000,000     (3) 03/31/2021 Common Stock 24,000,000 $ 0 24,000,000 D (4)  
Common Stock Options (to purchase shares of Common Stock) $ 0.0197               (5) 08/18/2022 Common Stock 10,000,000   10,000,000 D (4)  
Common Stock Options (to purchase shares of Common Stock) $ 0.025               (6) 06/30/2022 Common Stock 15,000,000   15,000,000 D (4)  
Common Stock Options (to purchase shares of Common Stock) $ 0.05               (7) 07/17/2019 Common Stock 5,000,000   5,000,000 D (8)  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
Margolis Jeff Eliot
C/O RESPIRERX PHARMACEUTCALS INC.
126 VALLEY ROAD, SUITE C
GLEN ROCK, NJ 07452
  X     VP, Treasurer & Secretary  

Signatures

 /s/ Jeff Eliot Margolis   04/04/2016
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) On September 14, 2015, the reporting person exercised warrants to purchase 507,374 shares of the registrant's common stock for $0.035 per share. The reporting person paid the exercise price on a cashless basis, resulting in the registrant withholding 483,872 of the warrant shares to pay the exercise price and issuing the reporting person the remaining 23,502 shares. These Warrants were acquired by Mr. Margolis in his capacity as President of Aurora Capital LLC, which served as placement agent in the Company's convertible note and warrant offering, and represent his share of the Placement Agent Warrants awarded in that transaction at each closing. The Warrants were exercisable on September 14, 2015.
(2) These Warrants were acquired by Mr. Margolis in his capacity as President of Aurora Capital LLC, which served as placement agent in the Company's unit offering with each unit consisting of one share of common stock and warrants to purchase two additional shares of common stock, and represent his share of the Placement Agent Warrants awarded at each closing of that transaction. The warrants are currently exercisable.
(3) These Common Stock Options vest in four equal installments: 25 percent on March 31, 2016 (the grant date), 25 percent on June 30, 2016, 25 percent on September 30, 2016, and 25 percent on December 31, 2016.
(4) Mr. Margolis holds these securities jointly with his spouse.
(5) These Common Stock Options vest in four equal installments: 25 percent on December 31, 2015, 25 percent on March 31, 2016, 25 percent on June 30, 2016, and 25 percent on September 30, 2016.
(6) These Common Stock Options vested in three installments: 50 percent on June 30, 2015, 25 percent on September 30, 2015, and 25 percent on December 31, 2015.
(7) These Common Stock Options vested in three equal installments on July 17, 2014, September 30, 2014 and December 31, 2014, and are all currently vested and exercisable.
(8) Mr. Margolis holds 2,727,273 of these securities jointly with his spouse.

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