Looking at options trading activity among components of the Russell 3000 index, there is noteworthy activity today in Sage Therapeutics Inc (SAGE), where a total volume of 4,128 contracts has been traded thus far today, a contract volume which is representative of approximately 412,800 underlying shares (given that every 1 contract represents 100 underlying shares). That number works out to 45.1% of SAGE's average daily trading volume over the past month, of 915,585 shares..