UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549




FORM 8-K

CURRENT REPORT


Pursuant to Section 13 or 15(d) of the
Securities Exchange Act of 1934.








Date of Report: December  22, 2005

(Date of earliest event reported)




ISCO International, Inc.

(Exact name of registrant as specified in its charter)





IL

(State or other jurisdiction 
of incorporation)


0-22302

(Commission File Number)


36-3688459

(IRS Employer 
Identification Number)






1001 Cambridge Drive, Elk Grove Village, IL

(Address of principal executive offices)

 

60007

(Zip Code)




847-391-9400
(Registrant's telephone number, including area code)




Not Applicable
(Former Name or Former Address, if changed since last report)








Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:



 
o Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

 
o Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

 
o Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

  

 
o Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

  







Item 7.01. Regulation FD Disclosure



The Company provided a brief update on business activity.


Item 9.01. Financial Statements and Exhibits


(a) Financial statements:

             None

(b) Pro forma financial information:

             None

(c) Exhibits

             99.1       Press Release of ISCO International, Inc. dated December  22, 2005






SIGNATURE


      Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be 
              signed on its behalf by the undersigned hereunto duly authorized.








Dated: December  22, 2005



ISCO INTERNATIONAL, INC.


By:  /s/ Frank J. Cesario                      

     Frank J. Cesario

     CFO








Exhibit Index



Exhibit No.
Description


99.1
Press Release of ISCO International, Inc. dated December  22, 2005