Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
FHM IV LP
   2. Issuer Name and Ticker or Trading Symbol
AMICUS THERAPEUTICS INC [FOLD] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
TWO UNION SQUARE, 601 UNION STREET STE 3200		 3. Date of Earliest Transaction (Month/Day/Year)
06/05/2007
(Street)

SEATTLE, WA 98101		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 06/05/2007   C   2,586,886 A (1) 2,586,886 I By Frazier Healthcare IV, LP (2)
Common Stock 06/05/2007   C   13,128 A (1) 13,128 I By Frazier Affiliates IV, LP (2)

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Series B Convertible Preferred Stock (1) 06/05/2007   C     988,446 (1)   (1)   (1) Common Stock 988,446 $ 0 0 I By Frazier Healthcare IV, LP (2)
Series B Preferred Stock (1) 06/05/2007   C     5,016 (1)   (1)   (1) Common Stock 5,016 $ 0 0 I By Frazier Affiliates IV, L.P. (2)
Series C Preferred Stock (1) 06/05/2007   C     1,011,088 (1)   (1)   (1) Common Stock 1,011,088 $ 0 0 I By Frazier Healthcare IV, LP (2)
Series C Preferred Stock (1) 06/05/2007   C     5,132 (1)   (1)   (1) Common Stock 5,132 $ 0 0 I By Frazier Affiliates IV, L.P. (2)
Series D Preferred Stock (1) 06/05/2007   C     572,310 (1)   (1)   (1) Common Stock 572,310 $ 0 0 I By Frazier Healthcare IV, LP (2)
Series D Preferred Stock (1) 06/05/2007   C     2,904 (1)   (1)   (1) Common Stock 2,904 $ 0 0 I By Frazier Affiliates IV, L.P. (2)
Warrant to purchase Series B (right to buy) $ 6.375 06/05/2007   X     15,042 (3)   (3)   (3) Common Stock 15,042 $ 0 0 I By Frazier Healthcare IV, LP (2)
Warrant to purchase Series B (right to buy) $ 6.375 06/05/2007   X     76 (3)   (3)   (3) Common Stock 76 $ 0 0 I By Frazier Affiliates IV, LP (2)
Series B Convertible Preferred Stock (1) 06/05/2007   J(3)   15,042 (1)     (1)   (1) Common Stock 15,042 $ 0 15,042 I By Frazier Healthcare IV, LP (2)
Series B Preferred Stock (1) 06/05/2007   J(3)   76 (1)     (1)   (1) Common Stock 76 $ 0 76 I By Frazier Affiiates IV, LP (2)
Series B Convertible Preferred Stock (1) 06/05/2007   C     15,042 (1)   (1)   (1) Common Stock 15,042 $ 0 0 I By Frazier Healthcare IV, LP (2)
Series B Preferred Stock (1) 06/05/2007   C     76 (1)   (1)   (1) Common Stock 76 $ 0 0 I By Frazier Affiiates IV, LP (2)

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
FHM IV LP
TWO UNION SQUARE
601 UNION STREET STE 3200
SEATTLE, WA 98101		     X    
FRAZIER HEALTHCARE IV LP

 		     X    
FRAZIER AFFILIATES IV LP

 		     X    

Signatures

 FHM IV, LP By: FHM IV, LLC, its General Partner /s/ Thomas S. Hodge, Chief Operation Officer   06/07/2007
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The Issuer's preferred stock automatically converted into Common Stock upon the closing of the Issuer's initial public offering and had no expiration date.
(2) These securities are owned directly by the entity listed. Frazier Healthcare IV, LP and Frazier Affiliates IV, LP, are joint filers. The designated filer, FHM IV, LP, serves as the general partner of Frazier Healthcare IV, LP and Frazier Affiliates IV, LP. FHM IV, LP disclaims beneficial ownership of the reported securities, except to the extent of its proportionate pecuniary interest therein.
(3) Exercised for cash immediately prior to the closing of the Issuer's initial public offering.
 
Remarks:
Exhibit 99.1 - Joint Filer Information

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