As filed with the Securities and Exchange Commission on April 3, 2001
                                                 Registration No. 333-55602

                    SECURITIES AND EXCHANGE COMMISSION
                          WASHINGTON, D.C. 20549

                              AMENDMENT NO. 1
                                    TO
                                 FORM S-3
                          REGISTRATION STATEMENT
                                   UNDER
                        THE SECURITIES ACT OF 1933

                             HESKA CORPORATION
          (EXACT NAME OF REGISTRANT AS SPECIFIED IN ITS CHARTER)

        DELAWARE                                          77-0192527
     (STATE OR OTHER                                   (I.R.S. EMPLOYER
     JURISDICTION OF                                IDENTIFICATION NUMBER)
    INCORPORATION OR
      ORGANIZATION)

                            1613 PROSPECT PARKWAY
                           FORT COLLINS, COLORADO
                                    80525
                               (970) 493-7272
(ADDRESS, INCLUDING ZIP CODE, AND TELEPHONE NUMBER, INCLUDING AREA CODE, OF
                 REGISTRANT'S PRINCIPAL EXECUTIVE OFFICES)


                              ROBERT B. GRIEVE
                           CHIEF EXECUTIVE OFFICER
                                     AND
                            CHAIRMAN OF THE BOARD
                              HESKA CORPORATION
                            1613 PROSPECT PARKWAY
                           FORT COLLINS, COLORADO
                                    80525
                               (970) 493-7272
    (NAME, ADDRESS, INCLUDING ZIP CODE, AND TELEPHONE NUMBER, INCLUDING
                     AREA CODE, OF AGENT FOR SERVICE)


                                 Copies to:
                           KAREN A. DEMPSEY, ESQ.
                          WILSON SONSINI GOODRICH &
                                   ROSATI
                          PROFESSIONAL CORPORATION
                                 ONE MARKET
                          SPEAR STREET TOWER, SUITE
                                    3300
                          SAN FRANCISCO, CALIFORNIA
                                    94105
                               (415) 947-2000
                            FAX:  (415) 947-2099

APPROXIMATE  DATE  OF  COMMENCEMENT OF PROPOSED SALE TO THE  PUBLIC:  From  time
to time after the effective date of this Registration Statement.

     If  the  only  securities being registered on this Form are  being  offered
pursuant  to dividend or interest reinvestment plans, please check the following
box. [   ]

     If any of the securities being registered on this Form are to be offered on
a  delayed or continuous basis pursuant to Rule 415 under the Securities Act  of
1933  (the  "Securities Act"), other than securities offered only in  connection
with dividend or interest reinvestment plans, check the following box. [X]

     If  this  Form is filed to register additional securities for  an  offering
pursuant to Rule 462(b) under the Securities Act, please check the following box
and  list  the  Securities  Act registration statement  number  of  the  earlier
effective registration statement for the same offering. [   ]

     If  this  Form is a post-effective amendment filed pursuant to Rule  462(c)
under  the  Securities Act, check the following box and list the Securities  Act
registration  statement  number of the earlier effective registration  statement
for the same offering. [   ]

     If  delivery of the prospectus is expected to be made pursuant to Rule 434,
please check the following box. [   ]


     THE  REGISTRANT HEREBY AMENDS THIS REGISTRATION STATEMENT ON SUCH DATE
OR  DATES  AS  MAY  BE  NECESSARY TO DELAY ITS  EFFECTIVE  DATE  UNTIL  THE
REGISTRANT  SHALL FILE A FURTHER AMENDMENT WHICH SPECIFICALLY  STATES  THAT
THIS REGISTRATION STATEMENT SHALL THEREAFTER BECOME EFFECTIVE IN ACCORDANCE
WITH SECTION 8(A) OF THE SECURITIES ACT OR UNTIL THE REGISTRATION STATEMENT
SHALL  BECOME  EFFECTIVE  ON  SUCH  DATE AS  THE  SECURITIES  AND  EXCHANGE
COMMISSION, ACTING PURSUANT TO SECTION 8(A), MAY DETERMINE.
PROSPECTUS

(Subject to Completion, dated April 3, 2001)

                                4,573,000 Shares

                                  [HESKA LOGO]

                                HESKA CORPORATION

                                  Common Stock

                                ________________

     This  prospectus  relates  to  the public  offering,  which  is  not  being
underwritten,  of up to 4,573,000 shares of our Common Stock which  is  held  by
some of our current stockholders.  We issued these shares of our Common Stock to
the selling stockholders identified in this prospectus in a private placement.

     The  prices  at  which  such  stockholders may  sell  the  shares  will  be
determined  by  the  prevailing market price for the  shares  or  in  negotiated
transactions.   We will not receive any of the proceeds from  the  sale  of  the
shares.

     Our  Common Stock is listed on the Nasdaq National Market under the  symbol
"HSKA."  On April 2, 2001, the closing price for our Common Stock was $  1.09375
per share.

                                ________________

     INVESTING  IN OUR COMMON STOCK INVOLVES CERTAIN RISKS.  SEE "RISK  FACTORS"
BEGINNING ON PAGE 3.

                                ________________

     THE SECURITIES AND EXCHANGE COMMISSION AND STATE SECURITIES REGULATORS HAVE
NOT APPROVED OR DISAPPROVED OF THESE SECURITIES OR DETERMINED IF THIS PROSPECTUS
IS  TRUTHFUL  OR  COMPLETE. ANY REPRESENTATION TO THE  CONTRARY  IS  A  CRIMINAL
OFFENSE.

                                ________________

                The date of this Prospectus is ___________, 2001.

     No  person  has  been authorized to give any information  or  to  make  any
representations other than those contained in this prospectus in connection with
the   offering  made  hereby,  and  if  given  or  made,  such  information   or
representations  must  not  be relied upon as having been  authorized  by  Heska
Corporation (referred to in this prospectus as "Heska," the "Company" and "we"),
any  selling stockholder or by any other person.  Neither the delivery  of  this
prospectus  nor  any sale made hereunder shall, under any circumstances,  create
any implication that information herein is correct as of any time subsequent  to
the  date  hereof.  This prospectus does not constitute an offer to  sell  or  a
solicitation  of an offer to buy any security other than the securities  covered
by  this prospectus, nor does it constitute an offer to or solicitation  of  any
person  in any jurisdiction in which such offer or solicitation may not lawfully
be made.

                       WHERE YOU CAN FIND MORE INFORMATION

     We  file annual, quarterly and special reports, proxy statements and  other
information with the Securities and Exchange Commission.  You may read and  copy
any  document  we file at the SEC's Public Reference Rooms in Washington,  D.C.,
New  York,  New  York  and  Chicago, Illinois.  The  Public  Reference  Room  in
Washington, D.C. is located at 450 Fifth Street, N.W.  Please call the SEC at 1-
800-SEC-0330  for further information on the public conference rooms.   Our  SEC
filings  are  also  available  to  the  public  from  the  SEC's  web  site   at
http://www.sec.gov.

     The  SEC  allows us to "incorporate by reference" the information  we  file
with  them,  which means that we can disclose important information  to  you  by
referring you to those documents.  The information incorporated by reference  is
considered to be part of this prospectus, and later information filed  with  the
SEC will update and supersede this information.  We incorporate by reference the
documents  listed below and any future filings made with the SEC  under  Section
13a,  13(c),  14 or 15(d) of the Securities Exchange Act of 1934 (the  "Exchange
Act") until our offering is completed.

 (1) Heska's Annual Report on Form 10-K, for the year ended December 31, 2000;

 (2) Heska's Current Report on Form 8-K filed with the Securities and Exchange
     Commission on February 7, 2001; and

 (3) The description of our Common Stock contained in our Registration Statement
     on Form 8-A, filed with the Securities and Exchange Commission on April 24,
     1997, and any further amendment  or report  filed hereafter for the purpose
     of updating any such description.

     You  may  request  a  copy  of these filings, at no  cost,  by  writing  or
telephoning us at the following address:

     Heska Corporation
     1613 Prospect Parkway
     Fort Collins, Colorado 80525
     (970) 493-7272

     You  should  rely  only  on the information incorporated  by  reference  or
provided in this prospectus or the prospectus supplement.  We have authorized no
one  to  provide you with different information.  We are not making an offer  of
these securities in any state where the offer is not permitted.  You should  not
assume  that the information in this prospectus or the prospectus supplement  is
accurate as of any date other than the date on the front of the document.



                                HESKA CORPORATION

     We  discover,  develop,  manufacture and  market  companion  animal  health
products.   We  have  a  sophisticated scientific  effort  devoted  to  applying
biotechnology  to  create a broad range of diagnostic, therapeutic  and  vaccine
products  for the large and growing companion animal health market.  In addition
to  our  diagnostic, therapeutic and vaccine products, we also  sell  veterinary
diagnostic  and patient monitoring instruments and offer diagnostic services  in
the  United States and Europe to veterinarians.  Our principal executive offices
are  located  at  1613 Prospect Parkway, Fort Collins, Colorado  80525  and  our
telephone number is (970) 493-7272.

                           FORWARD-LOOKING STATEMENTS

     This  prospectus and the documents incorporated herein by reference contain
forward-looking statements within the meaning of Section 27A of  the  Securities
Act  of  1933, as amended (the "Securities Act") and Section 21E of the Exchange
Act.   Words  such as "anticipates," "expects," "intends," "plans,"  "believes,"
"seeks,"  "estimates,"  variations of such words  and  similar  expressions  are
intended to identify such forward- looking statements.  These statements are not
guarantees of future performance and are subject to certain risks, uncertainties
and  assumptions that are difficult to predict.  Therefore, actual results could
differ materially from those expressed or forecasted in any such forward-looking
statements  as a result of certain factors, including those set forth  in  "Risk
Factors,"  as  well  as  those  noted in the documents  incorporated  herein  by
reference.  In connection with forward-looking statements that appear  in  these
disclosures,  investors should carefully review the factors set  forth  in  this
prospectus under "Risk Factors."

                                  RISK FACTORS

     Our  future operating results may vary substantially from period to  period
due to a number of factors, many of which are beyond our control.  The following
discussion  highlights some of these factors and the possible  impact  of  these
factors  on  future results of operations.  You should carefully consider  these
factors  before making an investment decision.  If any of the following  factors
actually occur, our business, financial condition or results of operations could
be  harmed.  In that case, the price of our common stock could decline, and  you
could experience losses on your investment.

WE HAVE A HISTORY OF LOSSES AND MAY NEVER ACHIEVE PROFITABILITY.

     We have incurred net losses since our inception in 1988 and, as of December
31,  2000, we had an accumulated deficit of $174.5  million.  We anticipate that
we  will continue to incur additional operating losses in the near term.   These
losses  have  resulted principally from expenses incurred in  our  research  and
development programs and from general and administrative and sales and marketing
expenses.   Even if we achieve profitability, we may not be able to  sustain  or
increase profitability on a quarterly or annual basis.

WE MAY NEED ADDITIONAL CAPITAL IN THE FUTURE.

     We  have  incurred  negative cash flow from operations since  inception  in
1988.   We  do not expect to generate positive cash flow sufficient to fund  our
operations  in  the  near  term.  Moreover, based on  our  current  projections,
including  the  proceeds of our recent private placement, we may need  to  raise
additional  capital  in  the future.  If necessary,  we  expect  to  raise  this
additional capital through one or more of the following:

     *    sale of additional securities;
     *    sale of various assets;
     *    licensing of technology; and
     *    sale of various products or marketing rights.

     Additional  capital may not be available on acceptable terms,  if  at  all.
Furthermore,  any  additional  equity financing  would  likely  be  dilutive  to
stockholders,  and  additional  debt  financing,  if  available,   may   include
restrictive  covenants  which  may limit our currently  planned  operations  and
strategies.  If adequate funds are not available, we may be required to  curtail
our  operations significantly and reduce discretionary spending  to  extend  the
currently  available  cash  resources, or  to  obtain  funds  by  entering  into
collaborative agreements or other arrangements on unfavorable terms.  If we fail
to  generate adequate funding on acceptable terms when we need to, our  business
could be substantially harmed.

WE HAVE LIMITED RESOURCES TO DEVOTE TO PRODUCT DEVELOPMENT AND
COMMERCIALIZATION.  IF WE ARE NOT ABLE TO DEVOTE RESOURCES TO PRODUCT
DEVELOPMENT AND COMMERCIALIZATION, WE MAY NOT BE ABLE TO DEVELOP OUR PRODUCTS.

     Our  strategy is to develop a broad range of products addressing  companion
animal  healthcare.   We believe that our revenue growth and  profitability,  if
any, will substantially depend upon our ability to:

     *    improve market acceptance of our current products;
     *    complete development of new products; and
     *    successfully introduce and commercialize new products.

     We  have  introduced some of our products only recently  and  many  of  our
products  are  still  under development.  Because we have limited  resources  to
devote   to  product  development  and  commercialization,  any  delay  in   the
development  of one product or reallocation of resources to product  development
efforts that prove unsuccessful may delay or jeopardize the development  of  our
other product candidates.  If we fail to develop new products and bring them  to
market, our ability to generate revenues will decrease.

     In  addition, our products may not achieve satisfactory market  acceptance,
and we may not successfully commercialize them on a timely basis, or at all.  If
our products do not achieve a significant level of market acceptance, demand for
our  products will not develop as expected and it is unlikely that we ever  will
become profitable.

WE MUST OBTAIN AND MAINTAIN COSTLY REGULATORY APPROVALS IN ORDER TO MARKET OUR
PRODUCTS.

     Many  of  the  products  we  develop and market are  subject  to  extensive
regulation  by  one or more of the United States Department of  Agriculture,  or
USDA,  the  Food  and Drug Administration, or FDA, the Environmental  Protection
Agency,  or EPA, and foreign regulatory authorities.  These regulations  govern,
among  other things, the development, testing, manufacturing, labeling, storage,
premarket  approval,  advertising,  promotion,  sale  and  distribution  of  our
products.   Satisfaction of these requirements can take several years  and  time
needed to satisfy them may vary substantially, based on the type, complexity and
novelty of the product.  The effect of government regulation may be to delay  or
to  prevent marketing of our products for a considerable period of time  and  to
impose costly procedures upon our activities.  We have experienced in the  past,
and  may  experience in the future, difficulties that could delay or prevent  us
from  obtaining  the regulatory approval or license necessary  to  introduce  or
market  our  products.   Regulatory approval of our  products  may  also  impose
limitations  on  the indicated or intended uses for which our  products  may  be
marketed.

     Among  the conditions for regulatory approval is the requirement  that  our
manufacturing  facilities or those of our third party manufacturers  conform  to
current   Good   Manufacturing  Practices.   The  FDA  and  foreign   regulatory
authorities  strictly enforce Good Manufacturing Practices requirements  through
periodic inspections.  We can provide no assurance that any regulatory authority
will  determine  that our manufacturing facilities or those of our  third  party
manufacturers   will  conform  to  Good  Manufacturing  Practices  requirements.
Failure  to  comply  with  applicable  regulatory  requirements  can  result  in
sanctions  being  imposed on us or the manufacturers of our products,  including
warning  letters,  product recalls or seizures, injunctions, refusal  to  permit
products  to be imported into or exported out of the United States, refusals  of
regulatory authorities to grant approval or to allow us to enter into government
supply  contracts,  withdrawals of previously approved  marketing  applications,
civil fines and criminal prosecutions.

FACTORS BEYOND OUR CONTROL MAY CAUSE OUR OPERATING RESULTS TO FLUCTUATE, AND
SINCE MANY OF OUR EXPENSES ARE FIXED, THIS FLUCTUATION COULD CAUSE OUR STOCK
PRICE TO DECLINE.

     We  believe that our future operating results will fluctuate on a quarterly
basis due to a variety of factors, including:

     *    the introduction of new products by us or by our competitors;
     *    market acceptance of our current or new products;
     *    regulatory and other delays in product development;
     *    product recalls;
     *    competition and pricing pressures from competitive products;
     *    manufacturing delays;
     *    shipment problems;
     *    product seasonality; and
     *    changes in the mix of products sold.

     We  have high operating expenses for personnel, new product development and
marketing.  Many of these expenses are fixed in the short term.  If any  of  the
factors listed above cause our revenues to decline, our operating results  could
be substantially harmed.

     Our  operating  results in some quarters may not meet the  expectations  of
stock  market  analysts and investors.  In that case, our stock  price  probably
would decline.

WE MUST MAINTAIN VARIOUS FINANCIAL AND OTHER COVENANTS UNDER OUR REVOLVING LINE
OF CREDIT AGREEMENT.

     Under  our  revolving  line of credit agreement with Wells  Fargo  Business
Credit, Inc., we are required to comply with various financial and non-financial
covenants, and we have made various representations and warranties.   Among  the
financial covenants are requirements for monthly minimum book net worth, minimum
quarterly net income and minimum cash balances or liquidity levels.  Failure  to
comply with any of the covenants, representations or warranties would negatively
impact  our ability to borrow under the agreement.  Our inability to  borrow  to
fund our operations could materially harm our business.

A SMALL NUMBER OF LARGE CUSTOMERS ACCOUNT FOR A LARGE PERCENTAGE OF OUR
REVENUES, AND THE LOSS OF ANY OF THEM COULD HARM OUR OPERATING RESULTS.

     We currently derive a substantial portion of our revenues from sales by our
subsidiary Diamond, which manufactures various of our products and products  for
other companies in the animal health industry.  Revenues from Diamond customers,
AgriLabs  and  Bayer, comprised approximately 17% and 12% of our total  revenues
for  the  years ended December 31, 2000 and 1999, respectively.  If we  are  not
successful in maintaining our relationships with our customers and obtaining new
customers, our business and results of operations will suffer.

WE OPERATE IN A HIGHLY COMPETITIVE INDUSTRY, WHICH COULD RENDER OUR PRODUCTS
OBSOLETE OR SUBSTANTIALLY LIMIT THE VOLUME OF PRODUCTS THAT WE SELL.  THIS WOULD
LIMIT OUR ABILITY TO COMPETE AND ACHIEVE PROFITABILITY.

     We   compete   with   independent  animal  health   companies   and   major
pharmaceutical  companies that have animal health divisions.  Companies  with  a
significant  presence  in  the  animal health  market,  such  as  American  Home
Products,  Bayer, IDEXX Laboratories, Inc., Intervet International B.V.,  Merial
Ltd.,  Novartis,  Pfizer  Inc.,  Pharmacia Animal  Health  and  Schering  Plough
Corporation,  have developed or are developing products that  compete  with  our
products  or would compete with them if developed.  These competitors  may  have
substantially  greater financial, technical, research and  other  resources  and
larger,   better-established   marketing,  sales,   distribution   and   service
organizations than us.  In addition, IDEXX, which has products that compete with
our  heartworm  diagnostic  products, prohibits its  distributors  from  selling
competitors' products, including ours.  Our competitors frequently offer broader
product lines and have greater name recognition than we do.  Our competitors may
develop  or  market  technologies  or  products  that  are  more  effective   or
commercially  attractive  than our current or future  products,  or  that  would
render  our technologies and products obsolete.  Further, additional competition
could come from new entrants to the animal healthcare market.  Moreover, we  may
not have the financial resources, technical expertise or marketing, distribution
or  support  capabilities  to  compete successfully.   If  we  fail  to  compete
successfully, our ability to achieve profitability will be limited.

WE HAVE LIMITED EXPERIENCE IN MARKETING OUR PRODUCTS, AND MAY BE UNABLE TO
COMMERCIALIZE OUR PRODUCTS.

     The  market  for companion animal healthcare products is highly fragmented,
with  discount  stores  and specialty pet stores accounting  for  a  substantial
percentage of sales.  Because we sell our companion animal health products  only
to  veterinarians, we may fail to reach a substantial segment of  the  potential
market,  and  we  may  not be able to offer our products  at  prices  which  are
competitive  with  those  of companies that distribute  their  products  through
retail  channels.  We currently market our products to veterinarians  through  a
direct sales force and through third parties.  To be successful, we will have to
continue  to  develop  and train our direct sales force  or  rely  on  marketing
partnerships or other arrangements with third parties to market, distribute  and
sell  our  products.   We may not successfully develop and  maintain  marketing,
distribution  or sales capabilities, and we may not be able to make arrangements
with  third  parties to perform these activities on satisfactory terms.   If  we
fail  to  develop a successful marketing strategy, our ability to  commercialize
our products and generate revenues will decrease.

WE HAVE GRANTED THIRD PARTIES SUBSTANTIAL MARKETING RIGHTS TO OUR PRODUCTS UNDER
DEVELOPMENT.  IF OUR CURRENT THIRD PARTY MARKETING AGREEMENTS ARE NOT
SUCCESSFUL, OR IF WE ARE UNABLE TO DEVELOP OUR OWN MARKETING CAPABILITIES OR
ENTER INTO ADDITIONAL MARKETING AGREEMENTS IN THE FUTURE, WE MAY NOT BE ABLE TO
DEVELOP AND COMMERCIALIZE OUR PRODUCTS.

     Our  agreements with our corporate marketing partners generally contain  no
minimum  purchase requirements in order for them to maintain their exclusive  or
co-exclusive marketing rights.  Novartis, Eisai or Ralston Purina or  any  other
collaborative  party  may  not  devote sufficient  resources  to  marketing  our
products.   Furthermore, there is nothing to prevent Novartis, Eisai or  Ralston
Purina  or  any other collaborative party from pursuing alternative technologies
or  products  that  may compete with our products.  If we fail  to  develop  and
maintain our own marketing capabilities, we may find it necessary to continue to
rely  on  potential or actual competitors for third party marketing  assistance.
Third  party  marketing  assistance  may not  be  available  in  the  future  on
reasonable terms, if at all.  If any of these events occur, we may not  be  able
to develop and commercialize our products and our revenues will decline.

WE MAY FACE COSTLY INTELLECTUAL PROPERTY DISPUTES.

     Our  ability to compete effectively will depend in part on our  ability  to
develop and maintain proprietary aspects of our technology and either to operate
without  infringing  the proprietary rights of others or  to  obtain  rights  to
technology  owned  by third parties.  We have United States  and  foreign-issued
patents  and are currently prosecuting patent applications in the United  States
and  with  various foreign countries.  Our pending patent applications  may  not
result  in  the  issuance of any patents or that any issued patents  will  offer
protection against competitors with similar technology.  Patents we receive  may
be  challenged, invalidated or circumvented in the future or the rights  created
by those patents may not provide a competitive advantage.  We also rely on trade
secrets, technical know-how and continuing invention to develop and maintain our
competitive position.  Others may independently develop substantially equivalent
proprietary  information and techniques or otherwise gain access  to  our  trade
secrets.

     The biotechnology and pharmaceutical industries have been characterized  by
extensive litigation relating to patents and other intellectual property rights.
In 1998, Synbiotics Corporation filed a lawsuit against us alleging infringement
of  a  Synbiotics patent relating to heartworm diagnostic technology,  and  this
litigation  remains  ongoing.   We  may  become  subject  to  additional  patent
infringement  claims and litigation in the United States or other  countries  or
interference  proceedings conducted in the United States  Patent  and  Trademark
Office to determine the priority of inventions.  The defense and prosecution  of
intellectual  property suits, USPTO interference proceedings, and related  legal
and  administrative proceedings are costly, time-consuming and distracting.   We
may  also need to pursue litigation to enforce any patents issued to us  or  our
collaborative partners, to protect trade secrets or know-how owned by us or  our
collaborative partners, or to determine the enforceability, scope  and  validity
of  the proprietary rights of others.  Any litigation or interference proceeding
will  result  in  substantial  expense to us and significant  diversion  of  the
efforts of our technical and management personnel.  Any adverse determination in
litigation   or  interference  proceedings  could  subject  us  to   significant
liabilities  to  third  parties.  Further, as a result of  litigation  or  other
proceedings,  we may be required to seek licenses from third parties  which  may
not be available on commercially reasonable terms, if at all.

     We  license  technology from a number of third parties.   The  majority  of
these  license agreements impose due diligence or milestone obligations  on  us,
and  in  some cases impose minimum royalty and/or sales obligations  on  us,  in
order  for  us to maintain our rights under these agreements.  Our products  may
incorporate technologies that are the subject of patents issued to,  and  patent
applications filed by, others.  As is typical in our industry, from time to time
we  and  our collaborators have received, and may in the future receive, notices
from  third parties claiming infringement and invitations to take licenses under
third  party  patents.  It is our policy that when we receive such  notices,  we
conduct  investigations of the claims they assert.  With respect to the  notices
we  have  received to date, we believe, after due investigation,  that  we  have
meritorious  defenses  to the infringement claims asserted.   Any  legal  action
against  us or our collaborators may require us or our collaborators  to  obtain
one  or  more  licenses in order to market or manufacture affected  products  or
services.   However, we cannot assure you that we or our collaborators  will  be
able  to  obtain  licenses  for technology patented by  others  on  commercially
reasonable  terms,  that  we will be able to develop alternative  approaches  if
unable  to  obtain  licenses, or that the current and future  licenses  will  be
adequate  for  the  operation of our businesses.  Failure  to  obtain  necessary
licenses  or to identify and implement alternative approaches could  prevent  us
and  our  collaborators from commercializing our products under development  and
could substantially harm our business.

WE HAVE LIMITED MANUFACTURING EXPERIENCE AND CAPACITY AND RELY SUBSTANTIALLY ON
THIRD PARTY MANUFACTURERS.  THE LOSS OF ANY THIRD PARTY MANUFACTURERS COULD
LIMIT OUR ABILITY TO LAUNCH OUR PRODUCTS IN A TIMELY MANNER, OR AT ALL.

     To  be successful, we must manufacture, or contract for the manufacture of,
our  current and future products in compliance with regulatory requirements,  in
sufficient  quantities and on a timely basis, while maintaining product  quality
and  acceptable  manufacturing costs.  In order to  increase  our  manufacturing
capacity, we acquired Diamond in April 1996.

     We  currently rely on third parties to manufacture those products we do not
manufacture  at our Diamond facility.  We currently have supply agreements  with
Quidel  Corporation for various manufacturing services relating to our point-of-
care  diagnostic tests, with Centaq, Inc. for the manufacture of our own allergy
immunotherapy treatment products and with various manufacturers for  the  supply
of   our   veterinary  diagnostic  and  patient  monitoring  instruments.    Our
manufacturing strategy presents the following risks:

 * Delays in the scale-up to quantities needed for product development could
   delay regulatory submissions and commercialization of our products  in
   development;

 * Our  manufacturing  facilities and those of some of  our  third  party
   manufacturers are subject to ongoing periodic unannounced inspection by
   regulatory authorities, including the FDA, USDA and other federal and state
   agency's for compliance with strictly enforced Good Manufacturing Practices
   regulations and similar foreign standards, and we do not have control over
   our third party manufacturers' compliance with these regulations and
   standards;

 * If we need to change to other commercial manufacturing contractors for
   certain of our products, additional regulatory licenses or approvals must
   be obtained for these contractors prior to our use.  This would require new
   testing and compliance inspections.  Any new manufacturer would have to be
   educated in, or develop substantially equivalent processes necessary for the
   production of our products;

 * If  market  demand  for our products increases suddenly,  our  current
   manufacturers might not be able to fulfill our commercial needs, which would
   require us to seek new manufacturing arrangements and may result in
   substantial delays in meeting market demand; and

 * We  may not have intellectual property rights, or may have to share
   intellectual property rights, to any improvements in the manufacturing
   processes or new manufacturing processes for our products.

     Any  of  these factors could delay commercialization of our products  under
development, interfere with current sales, entail higher costs and result in our
being unable to effectively sell our products.

     Our agreements with various suppliers of the veterinary medical instruments
require us to meet minimum annual sales levels to maintain our position  as  the
exclusive distributor of these instruments.  We may not meet these minimum sales
levels in the future, and maintain exclusivity over the distribution and sale of
these  products.   If  we are not the exclusive distributor of  these  products,
competition may increase.

WE DEPEND ON PARTNERS IN OUR RESEARCH AND DEVELOPMENT ACTIVITIES.  IF OUR
CURRENT PARTNERSHIPS AND COLLABORATIONS ARE NOT SUCCESSFUL, WE MAY NOT BE ABLE
TO DEVELOP OUR TECHNOLOGIES OR PRODUCTS.

     For  various  of  our proposed products, we are dependent on  collaborative
partners  to successfully and timely perform research and development activities
on  our  behalf.   These  collaborative partners may not complete  research  and
development  activities on our behalf in a timely fashion, or at  all.   If  our
collaborative partners fail to complete research and development activities,  or
fail  to  complete them in a timely fashion, our ability to develop technologies
and products will be impacted negatively and our revenues will decline.

WE DEPEND ON KEY PERSONNEL FOR OUR FUTURE SUCCESS.  IF WE LOSE OUR KEY PERSONNEL
OR ARE UNABLE TO ATTRACT AND RETAIN ADDITIONAL PERSONNEL, WE MAY BE UNABLE TO
ACHIEVE OUR GOALS.

     Our  future success is substantially dependent on the efforts of our senior
management  and  scientific team.  The loss of the services of  members  of  our
senior  management or scientific staff may significantly delay  or  prevent  the
achievement  of product development and other business objectives.   Because  of
the  specialized  scientific nature of our business, we depend substantially  on
our  ability to attract and retain qualified scientific and technical personnel.
There  is intense competition among major pharmaceutical and chemical companies,
specialized biotechnology firms and universities and other research institutions
for qualified personnel in the areas of our activities.  If we lose the services
of,  or  fail to recruit, key scientific and technical personnel, the growth  of
our business could be substantially impaired.

WE MAY FACE PRODUCT RETURNS AND PRODUCT LIABILITY LITIGATION AND THE EXTENT OF
OUR INSURANCE COVERAGE IS LIMITED.  IF WE BECOME SUBJECT TO PRODUCT LIABILITY
CLAIMS RESULTING FROM DEFECTS IN OUR PRODUCTS, WE MAY FAIL TO ACHIEVE MARKET
ACCEPTANCE OF OUR PRODUCTS AND OUR BUSINESS COULD BE HARMED.

     The testing, manufacturing and marketing of our current products as well as
those  currently under development entail an inherent risk of product  liability
claims  and  associated  adverse publicity.  Following  the  introduction  of  a
product,  adverse  side effects may be discovered.  Adverse publicity  regarding
such  effects could affect sales of our other products for an indeterminate time
period.  To date, we have not experienced any material product liability claims,
but  any  claim  arising in the future could substantially  harm  our  business.
Potential  product  liability  claims may exceed the  amount  of  our  insurance
coverage or may be excluded from coverage under the terms of the policy.  We may
not be able to continue to obtain adequate insurance at a reasonable cost, if at
all.  In the event that we are held liable for a claim against which we are  not
indemnified  or  for damages exceeding the $10 million limits of  our  insurance
coverage  or which results in significant adverse publicity against us,  we  may
lose revenue and fail to achieve market acceptance.

WE MAY BE HELD LIABLE FOR THE RELEASE OF HAZARDOUS MATERIALS, WHICH COULD RESULT
IN EXTENSIVE COSTS WHICH WOULD HARM OUR BUSINESS.

     Our  products  and  development  programs involve  the  controlled  use  of
hazardous  and  biohazardous materials, including chemicals, infectious  disease
agents  and various radioactive compounds.  Although we believe that our  safety
procedures  for  handling  and  disposing of  such  materials  comply  with  the
standards  prescribed  by  applicable local, state and federal  regulations,  we
cannot completely eliminate the risk of accidental contamination or injury  from
these materials.  In the event of such an accident, we could be held liable  for
any  fines,  penalties,  remediation costs or other damages  that  result.   Our
liability  for  the release of hazardous materials could exceed  our  resources,
which  could lead to a shut down of our operations.  In addition, we  may  incur
substantial  costs to comply with environmental regulations  as  we  expand  our
manufacturing capacity.

WE EXPECT TO EXPERIENCE VOLATILITY IN OUR STOCK PRICE, WHICH MAY AFFECT OUR
ABILITY TO RAISE CAPITAL IN THE FUTURE OR MAKE IT DIFFICULT FOR INVESTORS TO
SELL THEIR SHARES.

     The securities markets have from time to time experienced significant price
and  volume  fluctuations  that are unrelated to the  operating  performance  of
particular  companies.   The market prices of securities of  many  publicly-held
biotechnology companies have in the past been, and can in the future be expected
to  be,  especially volatile.  For example, in the last twelve months our  stock
price has ranged from a low of $0.59375 to a high of $4.50.  Fluctuations in the
trading  price or liquidity of our common stock may adversely affect our ability
to  raise  capital through future equity financings.  Factors that  may  have  a
significant  impact on the market price and marketability of  our  common  stock
include:

     *    announcements of technological innovations or new products by us or by
          our competitors;
     *    our quarterly operating results;
     *    releases of reports by securities analysts;
     *    developments or disputes concerning patents or proprietary rights;
     *    regulatory developments;
     *    developments in our relationships with collaborative partners;
     *    changes in regulatory policies;
     *    litigation;
     *    economic and other external factors; and
     *    general market conditions.

     In  the  past,  following periods of volatility in the market  price  of  a
company's  securities,  securities  class  action  litigation  has  often   been
instituted.   If a securities class action suit is filed against  us,  we  would
incur  substantial legal fees and our management's attention and resources would
be diverted from operating our business in order to respond to the litigation.

IF WE FAIL TO MEET NASDAQ NATIONAL MARKET LISTING REQUIREMENTS, OUR COMMON STOCK
WILL BE DELISTED AND BECOME ILLIQUID.

     Our common stock is currently listed on the Nasdaq National Market.  Nasdaq
has  requirements we must meet in order to remain listed on the Nasdaq  National
Market.   If  we  continue to experience losses from our operations  or  we  are
unable to raise additional funds, we might not be able to maintain the standards
for  continued quotation on the Nasdaq National Market, including a minimum  bid
price  requirement of $1.00.  If the minimum bid price of our common stock  were
to  remain below $1.00 for 30 consecutive trading days, or if we were unable  to
continue to meet Nasdaq's standards for any other reason, our common stock could
be delisted from the Nasdaq National Market.

     If as a result of the application of these listing requirements, our common
stock  were  delisted from the Nasdaq National Market, our  stock  would  become
harder  to buy and sell.  Further, our stock could be subject to what are  known
as the "penny stock" rules.  The penny stock rules place additional requirements
on  broker-dealers who sell or make a market in such securities.   Consequently,
if  we  were removed from the Nasdaq National Market, the ability or willingness
of  broker-dealers to sell or make a market in our common stock  might  decline.
As  a  result,  the ability for investors to resell shares of our  common  stock
could be adversely affected.

THE COMMON STOCK SOLD IN THIS OFFERING WILL INCREASE THE SUPPLY OF OUR COMMON
STOCK ON THE PUBLIC MARKET, WHICH MAY CAUSE OUR STOCK PRICE TO DECLINE.

     The  sale  into the public market of the common stock to be  sold  in  this
offering  could adversely affect the market price of our common stock.  Most  of
our   shares  of  common  stock  outstanding  are  eligible  for  immediate  and
unrestricted  sale  in  the  public market at any time.  Once  the  registration
statement  of  which  this  prospectus forms a part is declared  effective,  the
4,573,000 shares of common stock covered by this prospectus will be eligible for
immediate and unrestricted resale into the public market. The presence of  these
additional  shares of common stock in the public market may further depress  our
stock price.

                                 USE OF PROCEEDS

  Heska  will  not  receive  any of the proceeds from the  sale  of  the  shares
offered  by  this prospectus. All proceeds from the sale of the  shares  offered
hereby  will be for the account of the selling stockholders, as described below.
See "Selling Stockholders" and "Plan of Distribution."


                              SELLING STOCKHOLDERS

  The  following table sets forth as of March 23, 2001, the name of each of  the
selling  stockholders, the number of shares of common stock  that  each  selling
stockholder  owns, the number of shares of common stock owned  by  each  selling
stockholder  that may be offered for sale from time to time by this  prospectus,
and  the number of shares of common stock to be held by each selling stockholder
assuming the sale of all the common stock offered hereby.

  Some  of  the selling stockholders may distribute their shares, from  time  to
time, to their limited and/or general partners, who may sell shares pursuant  to
this prospectus. Each selling stockholder may also transfer shares owned by  him
by  gift, and upon any such transfer the donee would have the same right of sale
as the selling stockholder.

  The  shares  being  offered  by  the selling  stockholders  were  acquired  in
connection  with a private placement on February 6, 2001.  Except as  set  forth
below, none of the selling stockholders has had a material relationship with  us
within  the  past  three years other than as a result of the  ownership  of  our
common  stock.  We may amend or supplement this prospectus from time to time  to
update the disclosure set forth herein.

  
  
                                                          SHARES BENEFICIALLY      NUMBER OF       SHARES BENEFICIALLY
                                                                 OWNED              SHARES                OWNED
                                                          PRIOR TO OFFERING(1)    BEING OFFERED    AFTER OFFERING(1)(2)
NAME OF SELLING STOCKHOLDER                               --------------------    -------------   ---------------------
---------------------------                                NUMBER    PERCENT                        NUMBER     PERCENT
                                                          ---------  ---------                    ----------  ---------
                                                                                               
State of Wisconsin Investment Board (3)                   6,468,000    16.73%       1,000,000      5,468,000     14.15%
Charter Ventures II, L.P.(4).                             6,206,924    16.06%       1,000,000      5,206,924     13.47%
Lombard Odier & Cie(5)                                    2,774,200     7.18%       1,000,000      1,774,200      4.59%
Edith W. Martin, Ph.D.(6)                                    38,500       *            36,000          2,500         *
National Federation of Independent Business
 (NFIB) Corp Acct (7)                                       172,000       *            77,000         95,000         *
Norwalk Employees' Pension Plan (7)                         258,000       *           108,000        150,000         *
Public Employee Retirement System of Idaho (7)            1,135,000    2.94%          385,000        750,000      1.94%
City of Stamford Firemen's Pension Fund (7)                 138,000       *            38,000        100,000         *
Lazar Foundation (7)                                         63,000       *            38,000         25,000         *
Roanoke College (7)                                         138,000       *            38,000        100,000         *
HBL Charitable Unitrust (7)                                 38,000        *            38,000            -           -
Psychology Associates (7)                                   58,000        *            38,000         20,000         *
Peter Looram (7)                                            73,000        *            38,000         35,000         *
Mary C. Anderson (7)                                        77,000        *            77,000            -           *
Murray Capital, LLC (7)                                     38,000        *            38,000            -           -
The Meehan Investment Partnership I, L.P. (7)               98,000        *            58,000         40,000         *
Domenic J. Mizio (7)                                       132,000        *            77,000         55,000         *
Theeuwes Family Trust, Felix Theeuwes Trustee (7)           77,000        *            77,000            -           -
Wells Family LLC (7)                                       231,000        *           231,000            -           -
Albert L. Zesiger (7)                                      222,000        *           115,000        107,000         *
Barrie Ramsay Zesiger (7)                                  133,000        *            58,000         75,000         *
John J. & Catherine H. Kayola (7)                            8,000        *             8,000            -           -


______________________________
*   Represents less than 1% of our common stock.
(1) Based on 38,656,745 shares outstanding as of March 23, 2001.
(2) Assumes that each selling stockholder sells all shares registered under
    this registration statement.  However, to our knowledge, there are no
    agreements, arrangements or understandings with respect to the sale of
    any of our common stock, and each selling stockholder may decide not to
    sell his shares that are registered under this registration statement.
(3) Based upon information derived from a Schedule 13G filed on February 9,
    2001 by State of Wisconsin Investment Board pursuant to Section 13G of the
    Exchange Act and the rules promulgated thereunder, reporting its beneficial
    ownership of our common stock.  According to the Schedule 13G, State of
    Wisconsin Investment Board has sole power to vote and dispose of 5,468,000
    shares.  Also includes 1,000,000 shares purchased in a private placement on
    February 6, 2001.
(4) Represents 3,386,510 shares and options to purchase 1,000 shares of our
    common stock held by Charter Ventures and 2,818,414 shares and options to
    purchase 1,000 shares of our common stock held by Charter Ventures II,
    L.P., with respect to which Mr. A. Barr Dolan, one of our directors,
    disclaims beneficial ownership except to the extent of his proportionate
    share therein.  Mr. Dolan is a general partner of each of Charter Ventures
    and Charter Ventures II, L.P., and may be deemed a beneficial owner of the
    shares held by such entities because of shared voting power with respect to
    such shares.
(5) Shares listed consist of 2,755,000 shares held as custodian for the Lombard
    Odier Nutrition Fund, over which Lombard Odier & Cie and Lombard Odier Fund
    Managers S.A. share voting and dispositive power, and 19,200 shares held for
    the benefit of private and institutional clients.  Such clients have the
    right to receive or the power to direct the receipt of dividends from, or
    the proceeds from the sale of, such shares and retain sole voting power
    with respect to such shares.
(6) Dr. Edith Martin is one of our directors.  The amount of shares
    beneficially owned includes 2,300 shares of common stock issuable upon
    exercise of stock options currency exercisable with 60 days of
    March 23, 2001.
(7) Zesiger Capital Group LLC acted as the agent and attorney-in-fact for this
    selling stockholder in connection with the stockholder's acquisition from us
    of the shares offered by this selling stockholder under this prospectus.
    Zesiger Capital Group LLC is an investment adviser registered with the
    Securities and Exchange Commission under the Investment Advisers Act of
    1940.  This selling stockholder is an advisory client of Zesiger Capital
    Group LLC, and the shares offered by this selling stockholder under this
    prospectus are held in a discretionary client account managed by Zesiger
    Capital Group LLC. Zesiger Capital Group LLC disclaims beneficial
    ownership of these shares.

                              PLAN OF DISTRIBUTION

  Heska  is  registering 4,573,000 shares of Common Stock, par value  of  $0.001
per  share  on  behalf of certain selling stockholders.  Heska will  receive  no
proceeds  from this offering.  The shares may be offered by certain stockholders
of  Heska  or  by pledgees, donees, transferees or other successors in  interest
that  receive such shares as a gift, partnership distribution or other  non-sale
related transfer.  The shares were originally issued by Heska in connection with
the  Stock Purchase Agreement between Heska and the selling stockholders,  dated
February  1,  2001  (the  "Stock Purchase Agreement").   The  shares  are  being
registered  by Heska pursuant to the Stock Purchase Agreement.  The shares  were
issued  pursuant  to  exemptions  from  the  registration  requirements  of  the
Securities Act, provided by Section 4(2) thereof.

  The  selling stockholders will act independently of Heska in making  decisions
with  respect  to  the  timing,  manner and  size  of  each  sale.  The  selling
stockholders may sell the shares on the Nasdaq National Market, or otherwise, at
prices  and under terms then prevailing or at prices related to the then current
market price, at varying prices or at negotiated prices. The shares may be sold,
without limitation, by one or more of the following means of distribution: (a) a
block  trade  in which the broker-dealer so engaged will attempt  to  sell  such
shares as agent, but may position and resell a portion of the block as principal
to facilitate the transaction; (b) purchases by a broker-dealer as principal and
resale  by  such broker-dealer for its own account pursuant to this  prospectus;
(c)  an over-the-counter distribution in accordance with the rules of the Nasdaq
National  Market; (d) ordinary brokerage transactions and transactions in  which
the broker solicits purchasers; and (e) in privately negotiated transactions. To
the  extent required, this prospectus may be amended and supplemented from  time
to time to describe a specific plan of distribution.

  In  connection  with  distributions of the shares or  otherwise,  the  selling
stockholders  may enter into hedging transactions with broker-dealers  or  other
financial institutions. In connection with such transactions, broker-dealers  or
other  financial  institutions may engage in short sales of the  shares  in  the
course  of  hedging  the  positions they assume with selling  stockholders.  The
selling stockholders may also sell the shares short and redeliver the shares  to
close  out  such short positions. The selling stockholders may also  enter  into
option or other transactions with broker-dealers or other financial institutions
which  require the delivery to such broker-dealer or other financial institution
of  the  shares, which shares such broker-dealer or other financial  institution
may resell or otherwise transfer pursuant to this prospectus (as supplemented or
amended  to reflect such transaction). The selling stockholders may also  pledge
the  shares  to  a  broker-dealer or other financial institution,  and,  upon  a
default, such broker-dealer or other financial institution, may effect sales  of
the  pledged shares pursuant to this prospectus (as supplemented or  amended  to
reflect  such  transaction).  In addition, any  shares  that  qualify  for  sale
pursuant  to  Rule 144 may, at the option of the holder thereof, be  sold  under
Rule 144 rather than pursuant to this prospectus.

  Any  broker-dealer  participating in such transactions as  agent  may  receive
commissions from the selling stockholders and/or purchasers of the shares  (and,
if  it  acts  as  agent for the purchaser of such shares, from such  purchaser).
Usual  and  customary  brokerage fees will be paid by the selling  stockholders.
Broker-dealers  may  agree with the selling stockholders  to  sell  a  specified
number  of  shares at a stipulated price per share, and, to the  extent  such  a
broker-dealer  is unable to do so acting as agent for the selling  stockholders,
to  purchase as principal any unsold shares at the price required to fulfill the
broker-dealer commitment to the selling stockholders. Broker-dealers who acquire
shares  as  principal may thereafter resell such shares from  time  to  time  in
transactions  (which  may  involve cross and block transactions  and  which  may
involve sales to and through other broker-dealers, including transactions of the
nature   described  above)  in  the  over-the-counter  market,   in   negotiated
transactions or otherwise at market prices prevailing at the time of sale or  at
negotiated  prices, and in connection with such resales, may pay to  or  receive
from  the  purchasers  of such shares commissions computed as  described  above.
Such  broker-dealers and any other participating broker-dealers or  the  selling
stockholders  may be deemed to be "underwriters" within the meaning  of  Section
2(11)  of  the  Securities  Act  in connection with  such  sales  and  any  such
commission, discount or concession may be deemed to be underwriting discounts or
commissions under the Securities Act.  Because the selling stockholders  may  be
deemed  to  be  an  underwriter under Section 2(11) of the Securities  Act,  the
selling stockholders will be subject to the prospectus delivery requirements  of
the Securities Act.

  To  comply  with  the  securities laws of certain states, if  applicable,  the
shares  will  be sold in such jurisdictions only through registered or  licensed
brokers  or dealers. In addition, in certain states the shares may not  be  sold
unless  they have been registered or qualified for sale in the applicable  state
or  an exemption from the registration or qualification requirement is available
and is complied with.

  Under  applicable  rules and regulations under the Exchange Act,  any  persons
engaged  in  the  distribution of the shares may not  simultaneously  engage  in
market  making activities with respect to our common stock for a period  of  two
business  days prior to the commencement of such distribution.  In addition  and
without  limiting  the foregoing, each selling stockholder will  be  subject  to
applicable  provisions  of  the  Exchange  Act  and  the  associated  rules  and
regulations  thereunder,  including, without  limitation,  Regulation  M,  which
provisions  may limit the timing of purchases and sales of shares of our  common
stock  by  the selling stockholders.  Heska will make copies of this  prospectus
available  to  the selling stockholders and have informed them of the  need  for
delivery of copies of this prospectus to purchasers at or prior to the  time  of
any  sale  of the shares.  Heska assumes no obligation to so deliver  copies  of
this prospectus or any related prospectus supplement.

  At  the  time a particular offer of shares is made, if required, a  prospectus
supplement  will be distributed that will set forth the number of  shares  being
offered  and  the terms of the offering, including the name of any  underwriter,
dealer  or  agent,  the  purchase price paid by any underwriter,  any  discount,
commission and other item constituting compensation, any discount, commission or
concession allowed or reallowed or paid to any dealer, and the proposed  selling
price to the public.

  The  selling stockholders will be responsible for any fees, disbursements  and
expenses  of  any  counsel  for the selling stockholders.   All  other  expenses
incurred  in connection with the registration of the shares, including printer's
and  accounting  fees and the fees, disbursements and expenses  of  counsel  for
Heska will be borne by us up to a certain amount.  Commissions and discounts, if
any,  attributable  to  the sales of the shares will be  borne  by  the  selling
stockholders.  The selling stockholders may agree to indemnify any broker-dealer
that  participates in transactions involving sales of the shares against certain
liabilities, including liabilities arising under the Securities Act.  Heska will
indemnify  the  selling stockholders against claims arising out  of  any  untrue
statement  of  a material fact contained in this Registration Statement  or  any
omission  to  state  therein a material fact necessary  in  order  to  make  the
statement made therein not misleading.

  Heska  has  undertaken  to  keep  a  Registration  Statement  of  which   this
prospectus constitutes a part effective until the earlier of the disposition  of
the  securities offered hereby or two years measured from the effective date  of
this  Registration Statement.  After such period, if we choose not  to  maintain
the  effectiveness  of  the  Registration Statement  of  which  this  prospectus
constitutes  a  part, the securities issuable offered hereby may  not  be  sold,
pledged, transferred or assigned, except in a transaction which is exempt  under
the  provisions  of the Securities Act of pursuant to an effective  registration
statement thereunder.

                                  LEGAL MATTERS

  Certain  legal  matters  relating to the validity of  the  securities  offered
hereby  will  be  passed  upon for Heska by Wilson Sonsini  Goodrich  &  Rosati,
Professional Corporation, San Francisco, California.

                                     EXPERTS

     The  financial statements incorporated in this prospectus by  reference  to
the  Annual  Report on Form 10-K of Heska for the year ended December  31,  2000
have  been  so  incorporated in reliance on the report of Arthur  Andersen  LLP,
independent public accountants, given on the authority of said firm  as  experts
in giving said reports.

     PROSPECTIVE  INVESTORS MAY RELY ONLY ON THE INFORMATION CONTAINED  IN  THIS
PROSPECTUS. NEITHER HESKA NOR ANY SELLING STOCKHOLDERS HAS AUTHORIZED ANYONE  TO
PROVIDE PROSPECTIVE INVESTORS WITH INFORMATION DIFFERENT FROM THAT CONTAINED  IN
THIS  PROSPECTUS. THIS PROSPECTUS IS NOT AN OFFER TO SELL NOR IS IT  SEEKING  AN
OFFER  TO  BUY  THE SHARES IN ANY JURISDICTION WHERE THE OFFER OR  SALE  IS  NOT
PERMITTED.  THE INFORMATION CONTAINED IN THIS PROSPECTUS IS CORRECT ONLY  AS  OF
THE  DATE  OF  THIS PROSPECTUS, REGARDLESS OF THE TIME OF THE DELIVERY  OF  THIS
PROSPECTUS OR ANY SALE OF THE SHARES.









                                HESKA CORPORATION

                                4,573,000 SHARES
                                  COMMON STOCK



                                   PROSPECTUS





                                 _________, 2001





                                     PART II

                     INFORMATION NOT REQUIRED IN PROSPECTUS

ITEM 14. OTHER EXPENSES OF ISSUANCE AND DISTRIBUTION

  The  Company  will pay all expenses incident to the offering and sale  to  the
public  of  the shares being registered other than any commissions and discounts
of underwriters, dealers or agents and any transfer taxes. Such expenses are set
forth in the following table. All of the amounts shown are estimates except  for
the Securities and Exchange Commission registration fee.

  
  
                                     
         SEC Registration Fee           $  1,358
         Accounting fees and expenses     15,000
         Legal fees and expenses          20,000
         Miscellaneous                       142
                                        --------
             Total                      $ 36,500
                                        ========


ITEM 15. INDEMNIFICATION OF DIRECTORS AND OFFICERS

  Section   145  of  the  Delaware  General  Corporation  Law  allows  for   the
indemnification  of  officers,  directors and  any  corporate  agents  in  terms
sufficiently  broad  to indemnify such persons under certain  circumstances  for
liabilities  (including reimbursement for expenses incurred) arising  under  the
Securities  Act.   Our certificate of incorporation and our bylaws  provide  for
indemnification of our directors, officers, employees and other  agents  to  the
extent and under the circumstances permitted by the Delaware General Corporation
Law.   We  have  also entered into agreements with our directors  and  executive
officers  that  require  Heska, among other things, to  indemnify  them  against
certain  liabilities  that may arise by reason of their  status  or  service  as
directors  and  executive officers to the fullest extent permitted  by  Delaware
law.   We have also purchased directors and officers liability insurance,  which
provides  coverage against certain liabilities including liabilities  under  the
Securities Act.

ITEM 16. EXHIBITS

                                  EXHIBIT INDEX

     
     

   EXHIBIT
   NUMBER    NOTES  DESCRIPTION
  --------   -----  -----------
             
  5.1*             Opinion of Wilson Sonsini Goodrich & Rosati,
                   Professional Corporation
  10.26(a)#        Amended  and  Restated  Employment  Agreement  between
                   Registrant  and Giuseppe Miozzari dated June 9, 2000
  10.42      (1)   Stock Purchase Agreement dated February 1, 2001
  23.1*            Consent   of   Wilson  Sonsini  Goodrich   &   Rosati,
                   Professional Corporation (included in Exhibit 5.1)
  23.2             Consent    of   Arthur   Andersen   LLP,   independent
                   accountants
  24.1*            Power of Attorney (contained on Page II-4)

 
--------------------
 NOTES
 -----
 * Previously Filed
 # Indicates management contract or compensatory plan or arrangement.
 (1) Filed with Registrant's Current Report on Form 8-K on February 7, 2001.


ITEM 17. UNDERTAKINGS

(a)  The undersigned Registrant hereby undertakes:

     (1)  To file, during any period in which offers or sales are being made,  a
post-effective  amendment  to this Registration Statement  (i)  to  include  any
prospectus required by Section 10(a)(3) of the

     Securities Act of 1933, as amended (the "Securities Act"), (ii) to  reflect
in  the  prospectus any facts or events arising after the effective date of  the
registration  statement  (or the most recent post-effective  amendment  thereof)
which,  individually or in the aggregate, represent a fundamental change in  the
information  set  forth  in  the  registration statement.   Notwithstanding  the
foregoing,  any  increase or decrease in volume of securities  offered  (if  the
total  dollar  value  of  securities offered would not  exceed  that  which  was
registered) and any deviation from the low or high end of the estimated  maximum
offering  range  may  be  reflected in the form of  prospectus  filed  with  the
Securities and Exchange Commission pursuant to Rule 424(b) if, in the aggregate,
the  changes in volume and price represent no more than a 20 percent  change  in
the  maximum  aggregate  offering  price  set  forth  in  the  "Calculation   of
Registration  Fee" table in the effective registration statement, and  (iii)  to
include  any  material information with respect to the plan of distribution  not
previously  disclosed in the Registration Statement or any  material  change  to
such   information  in  the  Registration  Statement;  provided,  however,  that
paragraphs  (a)(1)(i)  and  (a)(1)(ii) above do not  apply  if  the  information
required  to  be included in a post-effective amendment by those  paragraphs  is
contained in the periodic reports filed by the Registrant pursuant to Section 13
or  Section  15(d) of the Securities Exchange Act of 1934 (the  "Exchange  Act")
that are incorporated by reference into this Registration Statement.

     (2)   That,  for  the  purpose  of  determining  any  liability  under  the
Securities Act, each such post-effective amendment shall be deemed to be  a  new
Registration  Statement  relating to the securities  offered  therein,  and  the
offering of such securities at that time shall be deemed to be the initial  bona
fide offering thereof.

     (3)  To remove from registration by means of a post-effective amendment any
of the securities being registered which remain unsold at the termination of the
offering.

(b)   The  undersigned  Registrant  hereby  undertakes  that,  for  purposes  of
determining  any  liability  under  the  Securities  Act,  each  filing  of  the
Registrant's  annual report pursuant to Section 13(a) or Section  15(d)  of  the
Exchange  Act  that  is incorporated by reference in the Registration  Statement
shall  be  deemed to be a new Registration Statement relating to the  securities
offered  therein,  and the offering of such securities at  that  time  shall  be
deemed to be the initial bona fide offering thereof.

(c)  Insofar as indemnification for liabilities arising under the Securities Act
may  be  permitted  to  directors,  officers  and  controlling  persons  of  the
Registrant  pursuant to the foregoing provisions, or otherwise,  the  Registrant
has  been  advised that in the opinion of the Securities and Exchange Commission
such indemnification is against public policy as expressed in the Securities Act
and is, therefore, unenforceable.  In the event that a claim for indemnification
against  such liabilities (other than the payment by the Registrant of  expenses
incurred  or paid by a director, officer or controlling person of the Registrant
in the successful defense of any action, suit or proceeding) is asserted by such
director, officer or controlling person in connection with the securities  being
registered, the Registrant will, unless in the opinion of its counsel the matter
has  been  settled  by controlling precedent, submit to a court  of  appropriate
jurisdiction  the question whether such indemnification by it is against  public
policy  as  expressed in the Securities Act and will be governed  by  the  final
adjudication of such issue.

(d)  The undersigned Registrant hereby undertakes that:

     (1)   for  purposes of determining any liability under the Securities  Act,
the  information  omitted from the form of prospectus  filed  as  part  of  this
registration  statement in reliance upon Rule 430A and contained in  a  form  of
prospectus filed by the Registrant pursuant to Rule 424(b)(1) or (4)  or  497(h)
under  the  Securities  Act  shall be deemed to be  part  of  this  Registration
Statement as of the time it was declared effective.

     (2)   for  the  purpose of determining liability under the Securities  Act,
each post-effective amendment that contains a form of prospectus shall be deemed
to  be  a new registration statement relating to the securities offered therein,
and  the  offering  of such securities at that time shall be deemed  to  be  the
initial bona fide offering thereof.


                                   SIGNATURES

  Pursuant  to  the requirements of the Securities Act of 1933,  the  Registrant
certifies  that it has reasonable grounds to believe that it meets  all  of  the
requirements for filing on Form S-3 and has duly caused this Amendment No. 1  to
the  Registration  Statement  to be signed on its  behalf  by  the  undersigned,
thereunto  duly authorized, in the City of Fort Collins, State of  Colorado,  on
April 3, 2001.
                                   HESKA CORPORATION

                                   By:        *
                                      ---------------------------
                                      Robert B. Grieve
                                      Chief Executive Officer and
                                      Chairman of the Board

  Pursuant  to the requirements of the Securities Act of 1933, this Registration
Statement  has  been  signed below by the following persons  on  behalf  of  the
Registrant on April 3, 2001.

     
     

             SIGNATURE                                  TITLE
-----------------------------        --------------------------------------------
                                  
             *                       Chief Executive Officer (Principal Executive
-----------------------------         Officer) and Chairman of the Board
Robert B. Grieve

/s/ Ronald L. Hendrick               Chief Financial Officer (Principal Financial
-----------------------------        and Accounting Officer), Executive Vice
Ronald L. Hendrick                   President and Secretary

             *
-----------------------------        Director
Fred M. Schwarzer

             *
-----------------------------        Director
A. Barr Dolan
             *
-----------------------------        Director
Lyle A. Hohnke
             *
-----------------------------        Director
William A. Aylesworth
             *
-----------------------------        Director
Lynnor B. Stevenson
             *
-----------------------------        Director
Edith W. Martin
             *
-----------------------------        Director
John F. Sasen, Sr.




By: /s/ Ronald L. Hendrick
    -------------------------
      Ronald L. Hendrick
      Attorney-in-Fact





                                INDEX TO EXHIBITS




  EXHIBIT
  NUMBER     NOTES   DESCRIPTION
  --------   -----   -----------------------------------------------
               
  5.1*               Opinion of Wilson Sonsini Goodrich & Rosati,
                     Professional Corporation
  10.26(a)#          Amended  and  Restated  Employment  Agreement  between
                     Registrant and Giuseppe Miozzari dated June 9, 2000
  10.42      (1)     Stock Purchase Agreement dated February 1, 2001
  23.1*              Consent   of   Wilson  Sonsini  Goodrich   &   Rosati,
                     Professional Corporation (included in Exhibit 5.1)
  23.2               Consent    of   Arthur   Andersen   LLP,   independent
                     accountants
  24.1*              Power of Attorney (contained on Page II-4)


---------------------
 NOTES
 -----
 * Previously Filed
 # Indicates management contract or compensatory plan or arrangement.
 (1) Filed with Registrant's Current Report on Form 8-K on February 7, 2001.