FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person * Casteel Marty   2. Issuer Name and Ticker or Trading Symbol SIMMONS FIRST NATIONAL CORP [SFNC] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner __X__ Officer (give title below) _____ Other (specify below) SEVP (Last) (First) (Middle) SIMMONS FIRST NATIONAL CORP, 501 MAIN STREET 3. Date of Earliest Transaction (Month/Day/Year) 01/16/2019 (Street) PINE BLUFF, AR 71601 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price SFNC 01/16/2019   A   9,040 A $ 26.27 104,879 D   SFNC 01/16/2019   F   4,302 D $ 26.27 100,577 D   SFNC 01/17/2019   M   1,576 A $ 26.43 102,153 D   SFNC 01/17/2019   F   714 D $ 26.43 101,439 D   SFNC               8,306 (1) D   SFNC               5,230 (2) D   SFNC               22,434 D

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Restricted Stock Unit

$ 26.43

01/17/2019

M

1,576 (3)

(4)

(4)

Common

1,576 (3)

$ 26.43

1,576 (3) (5)

D

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Casteel Marty SIMMONS FIRST NATIONAL CORP 501 MAIN STREET PINE BLUFF, AR 71601			SEVP

Signatures

/s/ Marty Casteel by Piper P. Erwin		01/18/2019
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	This number reflects the acquisition of 42 shares pursuant to the Company's Dividend Reinvestment Plan.
(2)	Total share amount increased by 654 shares due to company's Employee Stock Purchase Plan.
(3)	On February 8, 2018, the Company effected a 2-for-1 stock split. The number of shares/units reported in this Form 4 has been adjusted to reflect the stock split.
(4)	The Restricted Stock Unit vested on January 17, 2019.
(5)	The balance of the Restricted Stock Unit vests on January 17, 2020. SFNC shares will be delivered within 30 days of vesting. Events such as retirement, death, disability and other specified events in the agreement may result in earlier vesting.

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