Ownership Submission
FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Alrutz Michael Albert
 2. Date of Event Requiring Statement (Month/Day/Year)
02/05/2019		 3. Issuer Name and Ticker or Trading Symbol
CHIMERIX INC [CMRX]
(Last)
(First)
(Middle)
C/O CHIMERIX, INC., 2505 MERIDIAN PARKWAY, SUITE 340		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Principal Executive Officer
 5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

DURHAM, NC 27713		 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 56,645 (1)
D
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (Right to Buy)   (2) 06/01/2022 Common Stock 1,485 $ 2.38 D  
Stock Option (Right to Buy)   (2) 01/28/2024 Common Stock 9,000 $ 18.75 D  
Stock Option (Right to Buy)   (2) 08/26/2024 Common Stock 20,000 $ 25.75 D  
Stock Option (Right to Buy)   (2) 01/28/2025 Common Stock 28,000 $ 39.41 D  
Stock Option (Right to Buy) 08/01/2015(3) 08/01/2025 Common Stock 15,000 $ 53.74 D  
Stock Option (Right to Buy) 01/08/2016(3) 01/08/2026 Common Stock 178,000 $ 8.06 D  
Stock Option (Right to Buy) 01/24/2017(3) 01/24/2027 Common Stock 45,750 $ 5.14 D  
Stock Option (Right to Buy) 01/25/2018(3) 01/25/2028 Common Stock 135,000 $ 4.68 D  
Stock Option (Right to Buy) 01/23/2019(3) 01/23/2029 Common Stock 176,000 $ 2.41 D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Alrutz Michael Albert
C/O CHIMERIX, INC.
2505 MERIDIAN PARKWAY, SUITE 340
DURHAM, NC 27713		       Principal Executive Officer  

Signatures

/s/ Michael Alrutz 02/07/2019
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Amount includes (i) 12,500 unvested shares pursuant to a restricted stock unit award issued on May 9, 2016 and (ii) 11,437 unvested shares pursuant to a restricted stock unit award issued on January 24, 2017.
(2) Fully vested and exercisable.
(3) 1/48th of the shares will vest each month over a four year period following the vesting commencement date.

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