FORM 5 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b). Form 3 Holdings Reported Form 4 Transactions Reported

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 ANNUAL STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL OMB Number: 3235-0362 Expires: January 31, 2005 Estimated average burden hours per response... 1.0

1. Name and Address of Reporting Person * ANDREEFF DANE 2. Issuer Name and Ticker or Trading Symbol Ardea Biosciences, Inc./DE [ARDC] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director __X__ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) C/O ANDREEFF EQUITY ADVISORS LLC, 450 LAUREL ST STE 2105 3. Statement for Issuer's Fiscal Year Ended (Month/Day/Year) 12/31/2006 (Street) BATON ROUGE, LA 70801 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Reporting (check applicable line) _X_ Form Filed by One Reporting Person ___ Form Filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned at end of Issuer's Fiscal Year (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Amount (A) or (D) Price Common Stock 02/13/2006(2)   P4 6,164 A $ 3.5 1,203,848 I See footnote (1) Common Stock 04/04/2006   P4 165 A $ 3.55 1,203,848 I See footnote (1) Common Stock 04/05/2006   P4 842 A $ 3.55 1,203,848 I See footnote (1) Common Stock 04/17/2006   P4 722 A $ 3.65 1,203,848 I See footnote (1) Common Stock 04/18/2006   P4 19 A $ 3.65 1,203,848 I See footnote (1) Common Stock 04/19/2006   P4 389 A $ 3.65 1,203,848 I See footnote (1) Common Stock 04/20/2006   P4 25 A $ 3.65 1,203,848 I See footnote (1) Common Stock 04/21/2006   P4 107 A $ 3.65 1,203,848 I See footnote (1) Common Stock 04/30/2006   P4 226 A $ 5.4766 1,203,848 I See footnote (1) Common Stock 06/01/2006   S4 1,647 D $ 3.4638 1,203,848 I See footnote (1) Common Stock 01/03/2007   S4 2,541 D $ 4.2944 1,203,848 I See footnote (1) Common Stock 01/31/2007   S4 2,232 D $ 5.65 1,203,848 I See footnote (1) Common Stock 04/02/2007   S4 311 D $ 4.758 1,203,848 I See footnote (1) Common Stock 05/02/2007   S4 163 D $ 5.51 1,203,848 I See footnote (1) Common Stock 02/13/2006(2)   P4 100,417 A $ 3.5 1,203,848 I See footnote (1) Common Stock 04/03/2006   P4 17,205 A $ 3.54 1,203,848 I See footnote (1) Common Stock 04/04/2006   P4 2,842 A $ 3.55 1,203,848 I See footnote (1) Common Stock 04/05/2006   P4 14,494 A $ 3.55 1,203,848 I See footnote (1) Common Stock 04/10/2006   P4 11,756 A $ 3.61 1,203,848 I See footnote (1) Common Stock 04/11/2006   P4 4,114 A $ 3.62 1,203,848 I See footnote (1) Common Stock 04/17/2006   P4 12,453 A $ 3.65 1,203,848 I See footnote (1) Common Stock 04/18/2006   P4 2,226 A $ 3.65 1,203,848 I See footnote (1) Common Stock 04/19/2006   P4 6,699 A $ 3.65 1,203,848 I See footnote (1) Common Stock 04/20/2006   P4 425 A $ 3.65 1,203,848 I See footnote (1) Common Stock 04/21/2006   P4 1,842 A $ 3.65 1,203,848 I See footnote (1) Common Stock 08/01/2006   P4 17,554 A $ 3.7499 1,203,848 I See footnote (1) Common Stock 06/01/2006   S4 27,362 D $ 3.4638 1,203,848 I See footnote (1) Common Stock 01/03/2007   S4 27,456 D $ 4.2944 1,203,848 I See footnote (1)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.

SEC 2270 (9-02)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned at End of Issuer's Fiscal Year (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
ANDREEFF DANE C/O ANDREEFF EQUITY ADVISORS LLC 450 LAUREL ST STE 2105 BATON ROUGE, LA 70801	Â	  X	Â	Â

Signatures

/s/ Dane Andreeff		06/07/2007
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	This transaction was made by a fund that is not, itself, a 10% owner of the issuer's securities. The reporting person is reporting this transaction because he is the managing member of the fund's general partner and thus may be deemed an indirect beneficial owner of the fund's holdings. When these holdings are aggregated with the reporting person's other indirect holdings of this issuer's securities, he may be deemed an indirect beneficial owner of 10% or more of the issuer's securities.
(2)	The reporting person may be deemed to have become a 10% owner of the issuer's securities on this date. These holdings were reportable on a Form 3. The SEC's reporting system would not accept that form type to be listed in Table 1 of this Form 5 filing.

Note: File three copies of this Form, one of which must be manually signed. If space provided is insufficient, see Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.