UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM 8-K

CURRENT REPORT
Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): September 16, 2010

NuPathe Inc.
(Exact name of registrant as specified in its charter)

Delaware		001-34836		20-2218246
(State or other Jurisdiction of Incorporation)		(Commission File Number)		(IRS Employer Identification No.)

227 Washington Street Suite 200 Conshohocken, Pennsylvania		19428
(Address of Principal Executive Offices)		(Zip Code)

Registrant’s telephone number, including area code: (484) 567-0130

Not Applicable

(Former name or former address if changed since last report.)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

o Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

o Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

o Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

o Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Item 7.01		Regulation FD Disclosure.

On September 16, 2010, Jane H. Hollingsworth, the chief executive officer of NuPathe Inc. (the “Company”), is presenting a company overview at the Stifel Nicolaus 2010 Healthcare Conference. Attached as Exhibit 99.1 to this Current Report on Form 8-K is a copy of the presentation materials to be used in connection with the presentation. The presentation materials will be posted and an audio webcast of the presentation will be available, for approximately one month, on the Investor Relations page in the “Events and Presentations” section of the Company’s website at www.nupathe.com.

The information furnished pursuant to this Item 7.01 and the accompanying Exhibit 99.1 shall not be deemed to be “filed” for the purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liability of that section, and is not to be incorporated by reference into any filing of the Company.

Item 9.01		Financial Statements and Exhibits.

(d)

Exhibits.

Exhibit No.		Description
99.1		Stifel Nicolaus 2010 Healthcare Conference Presentation Materials.

SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

Dated: September 16, 2010

Exhibit Index

Exhibit		Description
99.1		Stifel Nicolaus 2010 Healthcare Conference Presentation Materials.