SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 ----------------------- SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(a) (Amendment No. 2)1 ARADIGM CORPORATION (Name of Issuer) Common Stock, no par value (Title of Class of Securities) 038508 (CUSIP Number) Ole Ramsby Novo Nordisk A/S Novo Alle DK-2880 Bagsvaerd Denmark Tel No.: +45 4444 8888 (Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications) February 10, 2003 (Date of Event Which Requires Filing of this Statement) If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of Rule 13d-1(e), 13d-1(f) or 13d-1(g), check the following box o. Note. Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See Rule 13d-7 for other parties to whom copies are to be sent. -------- 1 The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page. The information required in the remainder of this cover page shall not be deemed to be "filed" for the th purpose of Section 18 of the Securities Exchange Act of 1934 or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes). SCHEDULE 13D CUSIP No. 038508 Page 2 of 10 Pages ---------------- ------------------ 1 NAME OF REPORTING PERSONS I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY) Novo Nordisk A/S 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [] (b) [X] 3 SEC USE ONLY 4 SOURCE OF FUNDS* OO 5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e) [] 6 CITIZENSHIP OR PLACE OF ORGANIZATION The Kingdom of Denmark 7 SOLE VOTING POWER 1,020,612 NUMBER OF SHARES BENEFICIALLY OWNED BY 8 SHARED VOTING POWER EACH REPORTING PERSON WITH 22,889,002 9 SOLE DISPOSITIVE POWER 1,020,612 10 SHARED DISPOSITIVE POWER 6,847,757 11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 23,909,614 - See Item 5 12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES* [] 13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 56.6% - See Item 5 14 TYPE OF REPORTING PERSON* CO *SEE INSTRUCTIONS BEFORE FILLING OUT! Page 2 of 10 Novo Nordisk A/S, a publicly quoted Danish company ("Buyer") hereby amends and supplements its Report on Schedule 13D, originally filed on November 14, 2001 (as amended and supplemented, the "Schedule 13D") with respect to the shares of Common Stock, no par value (the "Shares"), of Aradigm Corporation, a California corporation (the "Issuer"). Unless otherwise indicated, each capitalized term used but not defined herein shall have the meaning assigned to such term in the Schedule 13D. Item 1. Security and Issuer. Item 2. Identity and Background. Item 3. Source and Amount of Funds or Other Consideration. Item 4. Purpose of Transaction. The following additional paragraphs are added after the last paragraph of Item 4 of the Schedule 13D: On February 10, 2003, the Issuer and certain other investors entered into a Securities Purchase Agreement (the "Securities Purchase Agreement"), whereby the Issuer agreed to sell a certain number of Shares and warrants, subject to shareholder approval and other closing conditions. In connection with the Securities Purchase Agreement, Buyer and certain other shareholders of the Issuer (collectively, the "Other Shareholders") entered into a Voting Agreement dated February 10, 2003 (the "Voting Agreement" a copy of which is attached hereto as Exhibit 2 and incorporated herein by reference), pursuant to which the parties agreed to vote all Shares registered in their respective names or beneficially owned by them (whether owned as of the date of the Voting Agreement or any time thereafter) to approve the Securities Purchase Agreement and other related documents and transactions. The scope of the Voting Agreement is limited to these matters and does not require the Buyer and the Other Stockholders to vote in any way on any matter except as set forth above. The Voting Agreement terminates on the earlier of: (i) the Closing Date (as defined in the Securities Purchase Agreement), (ii) the date on which the parties to the Voting Agreement terminate it by written consent of New Enterprise Associates and a majority in interest of the shareholders party to the Voting Agreement, (iii) the termination of the Securities Purchase Agreement and (iv) April 30, 2003. Item 5. Interest in Securities of the Issuer. (a) For the purposes of Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), Buyer may be deemed to beneficially own 23,909,614 Shares, or approximately 56.6% of the outstanding Shares, which includes Warrants to purchase 4,913,144 Shares and 1,536,226 shares of Preferred Stock (convertible into 6,144,904 Shares). (b) By virtue of the Voting Agreement (the details of which are set forth under Item 4 of this Schedule 13D), Buyer may be deemed to have the shared power to vote or direct the vote of the 4,983,197 Shares, warrants to purchase 4,913,144 Shares and the 1,536,226 shares of Preferred Stock (convertible into 6,144,904 Shares) held by the Other Stockholders for the limited purposes described in Item 4 of this Schedule 13D. The Reporting Person disclaims beneficial ownership of all such securities of the Issuer owned by the Other Stockholders. By virtue of the relationship described in Item 2 of this Schedule 13D, Buyer may be deemed to have the sole power to vote or direct the vote and sole power to dispose or direct the disposition of and vote of the 1,020,612 Shares held by it directly and the shared power to direct the disposition of and vote of the 6,847,757 Shares held by NN Pharmaceuticals. (c) None of Buyer, any of the persons named in Item 2 or any of the persons set forth on Schedule A, has effected any transaction in the Common Stock during the past 60 days. Page 3 of 10 (d) Inapplicable. (e) Inapplicable. Item 6. Contracts, Arrangements, Understandings or Relationships with Respect to Securities of the Issuer. See response to Item 4. Item 7. Material to be Filed as Exhibits. Exhibit 1: Stock Purchase Agreement dated as of October 22, 2001 between the Issuer and Buyer.# Exhibit 2: Voting Agreement dated as of February 10, 2003 between Buyer and certain other parties set forth on Exhibit A to such Voting Agreement. # Previously filed as an exhibit to the original Schedule 13D filed November 14, 2001. Page 4 of 10 SIGNATURES After reasonable inquiry and to the best knowledge and belief of the undersigned, the undersigned certifies that the information set forth in this statement is true, complete and correct. Date: February 28, 2003 NOVO NORDISK A/S By: /s/ Mads Ovlisen -------------------------------- Name: Mads Ovlisen Title: Chairman of the Board By: /s/ Kare Schultz -------------------------------- Name: Kare Schultz Title: Executive Vice President & COO Page 5 of 10 SCHEDULE A DIRECTORS AND EXECUTIVE OFFICERS OF BUYER The name, address, title, present principal occupation or employment of each of the directors and executive officers of Buyer are set forth below. If no address is given, the director's or officer's address is Novo Alle, DK-2880 Bagsvaerd, Denmark. The directors are designated with asterisks (*). Name and Citizenship Principal Occupation and Address -------------------- -------------------------------- *Mads 0vlisen Chairman of the Board Danish Novo Nordisk A/S Novo Alle, 6B2.22 2880 Bagsvaerd Denmark *Kurt Anker Nielsen Co-President & CEO Danish Novo A/S Krogshojvej 41, 9P2.05 2880 Bagsvaerd Denmark *Jan Ulf Sigvard Johansson CEO/Businessman Swedish Strandvagen 43, 4 tr. 114 56 Stockholm Sweden *Jorgen Wedel 29 Winsor Way Danish Weston, Massachusetts 02493 USA *Kurt Briner Director Swiss c/o Ebsa sa 47, rue du 31 Decembre CH-1211 Geneva 6 Switzerland *Niels Jacobsen President & CEO Danish William Demant Holding A/S Strandvejen 58 2900 Hellerup Denmark *Anne Marie Handrup Kverneland Laboratory Assistant Danish Novo Nordisk A/S Laurentsvej 22, 7X 2880 Bagsvaerd Denmark Page 6 of 10 Name and Citizenship Principal Occupation and Address -------------------- -------------------------------- *Johnny Henriksen Environmental Specialist Danish Novo Nordisk A/S Hummeltoftevej 49 Building SOC 1.18 2830 Virum Denmark *Stig Strobaek Electrician Danish Novo Nordisk, A/S Laurentsvej 22, 7X 2880 Bagsvaerd Denmark Lars Rebien Sorensen CEO Danish Novo Nordisk A/S Jesper Brandgaard CFO Danish Novo Nordisk A/S Kare Schultz Chief Operating Officer Danish Novo Nordisk A/S Mads Krogsgaard Thompsen Chief Science Officer Danish Novo Nordisk A/S Lars Almblom Jorgensen Chief of Staffs Danish Novo Nordisk A/S Lise Kingo Executive Vice President Danish Novo Nordisk A/S DIRECTORS AND EXECUTIVE OFFICERS OF NN NORTH AMERICA The name, address, title, present principal occupation or employment of each of the directors and executive officers of NN North America, are set forth below. If no address is given, the director's or officer's address is 405 Lexington Avenue, New York City, New York 10017. The directors are designated with asterisks (*). Name and Citizenship Principal Occupation and Address -------------------- -------------------------------- *James Shehan President and Secretary USA Novo Nordisk of North America, Inc. *Susan Jackson Vice President Communications USA Novo Nordisk Pharmaceuticals, Inc. 100 College Road West Princeton, NJ 08540-7810 *Phil Fornecker CFO and Treasurer USA Novo Nordisk of North America, Inc. Page 7 of 10 Name and Citizenship Principal Occupation and Address -------------------- -------------------------------- *Ole F. Ramsby Senior Vice President Legal Affairs Danish and General Counsel Novo Nordisk A/S Novo Alle 2880 Bagsvaerd Denmark Mark Stolp Assistant Treasurer USA Novo Nordisk of North America, Inc. Jerry Shilling Assistant Treasurer USA Novo Nordisk of North America, Inc. Kevin Rowland Assistant Treasurer USA Novo Nordisk of North America, Inc. Joan M. Schmidt Assistant Secretary USA Novo Nordisk of North America, Inc. DIRECTORS AND EXECUTIVE OFFICERS OF NN PHARMACEUTICALS The name, address, title, present principal occupation or employment of each of the directors and executive officers of NN Pharmaceuticals, are set forth below. If no address is given, the director's or officer's address is 100 College Road, Princeton, New Jersey 08540. The directors are designated with asterisks (*). Name and Citizenship Principal Occupation and Address -------------------- -------------------------------- *Martin Soeters President The Netherlands Novo Nordisk Pharmaceuticals, Inc. *Kare Schultz Chief Operating Officer Danish Novo Nordisk A/S *Barry Reit Vice President Regulatory Affairs Danish Novo Nordisk Pharmaceuticals, Inc. *Phil Fornecker Vice President Finance USA Novo Nordisk Pharmaceuticals, Inc. *Jim C. Shehan President USA Novo Nordisk of North America, Inc. 405 Lexington Avenue New York City, NY 10017 DIRECTORS AND EXECUTIVE OFFICERS OF NOVO A/S The name, address, title, present principal occupation or employment of each of the directors and executive officers of Novo A/S, are set forth below. If no address is given, the director's or officer's address is Krogshojvej 41, DK-2880 Bagsvaerd, Denmark. The directors are designated with asterisks (*). Name and Citizenship Principal Occupation and Address -------------------- -------------------------------- *Palle Marcus Chairman of the Board of Directors Danish Novo A/S Page 8 of 10 Name and Citizenship Principal Occupation and Address -------------------- -------------------------------- *Jorgen Boe Lawyer Danish Margrethevej 6 2960 Rungsted Kyst Denmark *Jan Ulf Sigvard Johansson CEO/Businessman Swedish Strandvagen 43, 4 tr. 114 56 Stockholm Sweden *Hans Kristian Werdelin Member Board of Directors Danish Novo A/S Henrik Gurtler Co-CEO Danish Novo A/S Kurt Anker Nielsen Co-CEO Danish Novo A/S DIRECTORS AND EXECUTIVE OFFICERS OF FOUNDATION The name, address, title, present principal occupation or employment of each of the directors and executive officers of the Foundation, are set forth below. If no address is given, the director's or officer's address is Brogardsvej 70, Post Box 71, DK-2820 Gentofte, Denmark. The directors are designated with asterisks (*). Name and Citizenship Principal Occupation and Address -------------------- -------------------------------- *Palle Marcus Chairman of Board of Directors Danish Novo Nordisk Foundation *Jorgen Boe Lawyer Danish Margrethevej 6 2960 Rungsted Kyst Denmark *Mads Ovlisen Member Board of Directors Danish Novo Nordisk Foundation Novo Nordisk A/S Novo Alle 6B2.22 2880 Bagsvaerd Denmark *Niels Borregaard Doctor Danish Enevangen 83 3450 Allerod Denmark *Jan Eric Lindsten Doctor Swedish Norr Malarstrand 78, 3 tr. S-112 35 Stockholm Sweden Page 9 of 10 Name and Citizenship Principal Occupation and Address -------------------- -------------------------------- *Hans Ejvird Hansen Director Danish Hegelsvej 12 2900 Charlotterlund Denmark *Ulla Morin Technician Danish Novo Nordisk Foundation *Soren Thuesen Pedersen Chemist Danish Novo Nordisk Foundation *Stig Strobaek Electrician Danish Novo Nordisk Foundation Gert Almind Frederiksen CEO Danish Novo Nordisk Foundation Page 10 of 10