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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                        --------------------------------

                                    FORM 8-K
                        --------------------------------


                                 CURRENT REPORT
                     PURSUANT TO SECTION 13 OR 15(D) OF THE
                         SECURITIES EXCHANGE ACT OF 1934

        DATE OF REPORT (DATE OF EARLIEST EVENT REPORTED): AUGUST 4, 2005

                             -----------------------

                                 CRYOLIFE, INC.
             (Exact name of registrant as specified in its charter)
                            -------------------------


                                                                                   
                FLORIDA                                 1-13165                              59-2417093
     (State or Other Jurisdiction              (Commission File Number)                     (IRS Employer
           of Incorporation)                                                             Identification No.)


              1655 ROBERTS BOULEVARD, N.W., KENNESAW, GEORGIA 30144
               (Address of principal executive office) (zip code)

       REGISTRANT'S TELEPHONE NUMBER, INCLUDING AREA CODE: (770) 419-3355

          -------------------------------------------------------------
          (Former name or former address, if changed since last report)

                            -------------------------

     Check the  appropriate  box below if the Form 8-K  filing  is  intended  to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

|_|  Written  communications  pursuant to Rule 425 under the  Securities Act (17
     CFR 230.425)

|_|  Soliciting  material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
     240.14a-12)

|_|  Pre-commencement   communications  pursuant  to  Rule  14d-2(b)  under  the
     Exchange Act (17 CFR 240.14d-2(b))

|_|  Pre-commencement   communications  pursuant  to  Rule  13e-4(c)  under  the
     Exchange Act (17 CFR 240.13e-4(c))

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ITEM 2.02  RESULTS OF OPERATIONS AND FINANCIAL CONDITION.

The information  provided  pursuant to this Item 12 is to be considered  "filed"
under the Securities  Exchange Act of 1934 ("Exchange  Act") and incorporated by
reference into those filings of CryoLife, Inc. ("CryoLife") that provide for the
incorporation  of all reports and documents filed by CryoLife under the Exchange
Act.

On August 4, 2005,  CryoLife  issued a press release  announcing its results for
the quarter  ended June 30,  2005.  CryoLife  hereby  incorporates  by reference
herein the  information  set forth in its Press  Release dated August 4, 2005, a
copy of which is attached hereto as Exhibit 99.1.  Except as otherwise  provided
in the press release, the press release speaks only as of the date of such press
release and such press release shall not create any implication that the affairs
of CryoLife have continued unchanged since such date.

Except for the historical  information  contained in this report, the statements
made  by  CryoLife  are  forward-looking   statements  that  involve  risks  and
uncertainties. All such statements are subject to the safe harbor created by the
Private  Securities  Litigation Reform Act of 1995.  CryoLife's future financial
performance could differ  significantly  from the expectations of management and
from results expressed or implied in the Press Releases. For further information
on  other  risk  factors,  please  refer  to the  "Risk  Factors"  contained  in
CryoLife's  Form 10-K for the year ended December 31, 2004,  CryoLife's Form S-3
(Registration  No.  333-121406),  as filed  with  the  Securities  and  Exchange
Commission  ("SEC") and any  subsequent  SEC  filings.  CryoLife  disclaims  any
obligation or duty to update or modify these forward-looking statements.

Included in Exhibit  99.1,  as attached,  is the  following  non-GAAP  financial
measure:

     o    Adjusted net loss excluding a charge for settlement of the shareholder
          class action lawsuit and a non-cash charge for the change in the value
          of the derivative  related to the Company's 6%  convertible  preferred
          stock*

     *    Adjusted net loss excluding a charge for settlement of the shareholder
          class action lawsuit and a non-cash charge for the change in the value
          of the derivative  related to the Company's 6%  convertible  preferred
          stock is presented and deemed useful by management in order to present
          the  Company's  2005  results as more readily  comparable  to its 2004
          results.   The   Company's   2004  numbers  do  not  include   charges
          attributable to the settlement of the shareholder class action lawsuit
          nor  non-cash  charges  for the change in the value of the  derivative
          related to the Company's 6% convertible preferred stock.

ITEM 9.01  FINANCIAL STATEMENTS AND EXHIBITS.

     (a) Financial Statements.

     (b) Pro Forma Financial Information.

     (c) Exhibits.

         Exhibit Number             Description
         --------------             -----------
         99.1                       Press Release dated August 4, 2005




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                                   SIGNATURES

     Pursuant  to the  requirements  of the  Securities  Exchange  Act of  1934,
CryoLife,  Inc.  has duly  caused  this report to be signed on its behalf by the
undersigned hereunto duly authorized.

                                      CRYOLIFE, INC.



Date:  August 4, 2005                 By: /s/ D. Ashley Lee
                                          -----------------------------------
                                          Name:  D. Ashley Lee
                                          Title: Executive Vice President, Chief
                                          Operating Officer and Chief Financial 
                                          Officer





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                                  EXHIBIT INDEX


Exhibit Number             Description
--------------             -----------
99.1                       Press Release dated August 4, 2005




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