SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM 6-K

Report of Foreign Issuer Pursuant to Rule 13a-16 or 15d-16

of the Securities Exchange Act of 1934

11 August 2004

        NOVO NORDISK A/S       
(Exact name of Registrant as specified in its charter)

Novo Allé
DK- 2880, Bagsvaerd
                                  Denmark                                 
(Address of principal executive offices)

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F

Form 20-F [X] Form 40-F [  ]

Indicate by check mark whether the registrant by furnishing the information contained in this Form is also thereby furnishing the information to the Commission pursuant to Rule 12g3-2(b) under the Securities Exchange Act of 1934.

Yes [  ]  No [X]

If “Yes” is marked, indicate below the file number assigned to the registrant in connection with Rule 12g-32(b):82-_____________________

 

   

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf of the undersigned, thereunto duly authorized.

Date: 11 August 2004

NOVO NORDISK A/S


Lars Rebien Sørensen, President and Chief Executive Officer
 

 

   

Stock Exchange Announcement
Financial statement for the first half of 2004

11 August 2004

Novo Nordisk increased operating profit by 12%

Operating profit for 2004 is now expected to grow by slightly more than 5%

Sales increased by 14% measured in local currencies in the first half of 2004. Measured in Danish kroner sales increased by 10%.
Sales of insulin analogues increased by 90% measured in local currencies. In the US, analogue sales more than doubled.
NovoSeven® sales increased by 17% measured in local currencies.
Operating profit increased by 12% to DKK 3,427 million, whereas net profit of DKK 2,367 million was in line with net profit in the first half of 2003. Earnings per share (diluted) increased by 1% to DKK 6.97.
Lars Rebien Sørensen, president & CEO, said, "Strategically important products like the insulin analogues and NovoSeven® continue to drive sales growth and enable us to raise our expectations for growth in underlying operating profit in 2004.”
Following consultation with the European regulatory authorities, Novo Nordisk expects to file an application for marketing approval in Europe for the use of NovoSeven® in connection with blunt trauma. Filing is expected in the first quarter of 2005 and could lead to an approval for the blunt trauma indication later in 2005.
Despite a continued challenging currency environment, the expectation for sales growth in 2004 remains around 10%, whereas operating profit now is expected to grow by slightly more than 5%.

Stock Exchange Announcement No 43 / 2004     Page 1 of 16
         
Novo Nordisk A/S

Investor Relations
Novo Allé
2880 Bagsværd

Denmark
Telephone:
+45 4444 8888

Telefax:
+45 4443 6633
Internet:
www.novonordisk.com
CVR Number:
24256790

 

   

Financial statement first half 2004


As of 1 January 2004, the accounting policies have been changed to comply with International Financial Reporting Standards (IFRS). The accounting policies used in this unaudited interim financial report are consistent with those used in the Annual Financial Report 2003 except for the changes described in the section ‘Adoption of IFRS in 2004’ in the Annual Financial Report 2003, which describes the changes from the historically applied Danish GAAP to IFRS. Free cash flow is defined as cash flow from operating activities plus cash flow from investing activities less net change in marketable securities (>3 months).

(Amounts below in DKK million except average number of shares outstanding, earnings per share and full-time employees).

Income statement H1 2004     H1 2003     % change
H1 2003
to H1 2004
         
Sales 13,789   12,533   10%
         
Gross profit 9,996   9,067   10%
Gross margin 72.5%   72.3%  
         
Sales and distribution costs 3,963   3,626   9%
Percent of sales 28.7%   28.9%  
         
Research and development costs 2,013   1,906   6%
Percent of sales 14.6%   15.2%  
         
Administration costs 896   870   3%
Percent of sales 6.5%   6.9%  
         
Licence fees and other operating income 303   397   (24%)
           
Operating profit 3,427   3,062   12%
Operating margin 24.9%   24.4%  
           
Share of profit in associated companies (109)   (97)   (12%)
Other net financial income 216   618   (65%)
Profit before tax 3,534   3,583   (1%)
           
Net profit 2,367   2,361   0%
Net profit margin 17.2%   18.8%    
           
Other key numbers          
           
Earnings per share (in DKK) - diluted 6.97   6.87   1%
         
Average number of shares outstanding (million) - diluted 339.8   342.0  
           
Depreciation, amortisation and impairment losses 767   665   15%
Capital expenditure 1,034   985   5%
           
Cash flow from operating activities 3,060   3,611   (15%)
Free cash flow 1,842   2,617   (30%)
           
Equity 24,928   22,807   9%
Equity ratio 72.8%   68.9%    
Total assets 34,248   33,103   3%
           
Full-time employees at the end of the period 19,631   18,465   6%

To facilitate the performance evaluation in the first half of 2004 all relevant quarterly numbers and ratios for 2003 and 2004 using IFRS have been made available in the appendices to this announcement.



Stock Exchange Announcement No 43 / 2004     Page 2 of 16
         
Novo Nordisk A/S

Investor Relations
Novo Allé
2880 Bagsværd

Denmark
Telephone:
+45 4444 8888

Telefax:
+45 4443 6633
Internet:
www.novonordisk.com
CVR Number:
24256790

 

   

Sales development by segments

Sales increased by 14% measured in local currencies. Growth was realised both within the diabetes care and the biopharmaceuticals segments - primarily driven by strategically important products like the insulin analogues NovoRapid®and NovoMix® 30 as well as NovoSeven® and Norditropin®SimpleXx®.


Sales
H1 2004
DKK mn
   Growth
as
reported
   Growth
in local
currencies
   Share of
growth
in local
currencies
The diabetes care segment      
Insulin analogues 1,938   82%   90%   55%
Human insulin and insulin-related sales 6,901   (3%)   0%   0%
Oral antidiabetic products 801   21%   28%   10%
Diabetes care - total 9,640   9%   13%   65%
               
The biopharmaceuticals segment              
NovoSeven® 2,120   10%   17%   18%
Growth hormone therapy 1,116   7%   10%   6%
Other products 913   19%   24%   11%
Biopharmaceuticals - total 4,149   11%   16%   35%
               
Total sales 13,789   10%   14%   100%

Sales growth was realised in all regions; especially North America, constituting 26% of total sales, experienced strong growth.

The diabetes care segment

Sales of diabetes care products grew by 13% measured in local currencies compared to the first half of 2003 and by 9% measured in Danish kroner to DKK 9,640 million.

Insulin analogues, human insulin and insulin-related products

Sales of insulin analogues, human insulin and insulin-related products increased by 12% measured in local currencies and by 9% to DKK 8,839 million measured in Danish kroner. All regions contributed to growth both measured in local currencies and in Danish kroner.

Sales of insulin analogues increased by 90% measured in local currencies and by 82% in Danish kroner to DKK 1,938 million in the first half of 2004. Novo Nordisk’s insulin analogue market share continues to increase - and now exceeds 25% of the world market. Solid growth rates were realised in all regions with North America as the primary growth driver followed by Europe. Sales of insulin analogues continue to drive growth and constitute more than 20% of Novo Nordisk’s total sales of all insulin products.

The feedback from the Swiss market since the launch of Novo Nordisk’s long-acting insulin analogue, Levemir®, has been positive and the product currently has a market share of about 10% of the long-acting segment. Towards the end of June, Levemir® was launched in the UK and recently in Finland. Novo Nordisk still expects to launch Levemir® in other key European markets later this year.

North America
Sales in North America increased by 26% in local currencies in the first half of 2004 and by 15% measured in Danish kroner. Sales growth was driven by a solid underlying market growth

Stock Exchange Announcement No 43 / 2004     Page 3 of 16
         
Novo Nordisk A/S

Investor Relations
Novo Allé
2880 Bagsværd

Denmark
Telephone:
+45 4444 8888

Telefax:
+45 4443 6633
Internet:
www.novonordisk.com
CVR Number:
24256790

 

   

as well as gain of market share. The increasing market share was primarily driven by NovoLog® and NovoLog® Mix, reflecting market share gains in the retail segment.

Europe
Sales in Europe increased by 5% measured in both local currencies and in Danish kroner. Growth is driven by sales of the insulin analogues NovoRapid® and NovoMix® 30 within the short-acting and premixed segments, which in total constitute some 70% of the European insulin market. In the first half of 2004 growth in insulin sales continued to be negatively impacted by price-focused healthcare reforms in some countries.

Japan & Oceania
Sales in Japan & Oceania increased by 13% in both local currencies and in Danish kroner. Growth is driven by sales of NovoRapid® and NovoRapid® Mix 30, the latter launched in Japan in late 2003. Both analogues are launched in FlexPen® which, together with InnoLet®, facilitates the conversion from durable to disposable devices.

International Operations
Sales within International Operations increased by 13% in local currencies and by 7% measured in Danish kroner. The main growth driver within International Operations is sales of human insulin, driven especially by China and Brazil. However, also insulin analogues are adding to growth, driven by a strong performance particularly in Turkey. Also Novo Nordisk’s insulin delivery systems continued to penetrate the markets within International Operations, as about 55% of sales were realised in devices compared to around 45% in the first half of 2003.

Oral antidiabetic products

Sales of oral antidiabetic products increased in all regions and in total by 28% measured in local currencies and 21% measured in Danish kroner to DKK 801 million. This development was partly caused by a low level of sales in the first half of 2003 in the US, due to a relatively low inventory level at wholesalers at the end of the first half of 2003.

The biopharmaceuticals segment

Sales within the biopharmaceuticals segment increased by 16% in local currencies compared to the first half of 2003 and by 11% measured in Danish kroner to DKK 4,149 million.

NovoSeven®

Sales of NovoSeven® increased by 17% in local currencies compared to the same period last year. Measured in Danish kroner sales increased by 10% to DKK 2,120 million. Sales growth for NovoSeven® was primarily driven by Europe and North America.

A number of factors contributed to the NovoSeven® sales growth in the first half of 2004. Due to the high penetration within spontaneous bleeds for congenital inhibitor patients, the predominant part of the growth within the inhibitor segment has been generated by treatment of acquired haemophilia patients and usage of NovoSeven® in connection with elective surgery. Treatment of spontaneous bleeds for congenital inhibitor patients remains the largest area of use. In addition, sales are perceived to have been positively affected by increased investigational use of NovoSeven®.

Growth hormone therapy (Norditropin® and Norditropin® SimpleXx®)

In local currencies sales of Norditropin® and Norditropin®SimpleXx® products increased by 10% compared to the first half of 2003. Measured in Danish kroner sales increased by 7% to DKK 1,116 million and were driven by Europe and North America, whereas sales in Japan

Stock Exchange Announcement No 43 / 2004     Page 4 of 16
         
Novo Nordisk A/S

Investor Relations
Novo Allé
2880 Bagsværd

Denmark
Telephone:
+45 4444 8888

Telefax:
+45 4443 6633
Internet:
www.novonordisk.com
CVR Number:
24256790

 

   

decreased partly due to the government-mandated reduction in reimbursement prices as of April 2004.

Other products

Sales of other products within the biopharmaceuticals segment, which predominantly consists of hormone replacement therapy (HRT) related products, grew by 24% in local currencies and by 19% in Danish kroner to DKK 913 million.

Sales growth in the first half of 2004 was positively impacted by the change in July 2003 of the US distribution set-up for Novo Nordisk’s HRT products and by the continued market penetration of the low-dose continuous combined product Activella® and the local oestrogen product Vagifem®. In the regions outside North America, sales decreased by 20% measured in Danish kroner, broadly in line with the contraction in the overall HRT market.

Costs

The cost of goods sold increased by 9% to DKK 3,793 million, leaving the gross margin at 72.5%, an increase from 72.3% in the first half of 2003. The gross margin continued to show a positive development, reflecting continued productivity improvements and a more favourable product mix. The positive development was to some extent countered by the lower average exchange rates for especially the US dollar and US dollar-related currencies compared to the first half of 2003.

Total non-production-related costs increased by 7% to DKK 6,872 million. The increase in non-production-related costs reflects especially costs related to sales and distribution. Costs of sales and distribution increased in line with sales - partly related to the increased sales force in the US.

Net financials

Net financials showed a net income of DKK 107 million in the first half of 2004 compared to DKK 521 million in the same period in 2003. Included in net financials are foreign exchange hedging gains, primarily related to the hedging of the US dollar, of DKK 174 million compared to DKK 843 million in the first half of 2003.

Outlook 2004

Novo Nordisk now expects 11-14% growth in sales for 2004 measured in local currencies based on continued market penetration of Novo Nordisk’s insulin analogue portfolio, combined with expectations of increasing NovoSeven® and Norditropin® SimpleXx® sales. Operating profit for 2004, measured in local currencies and excluding the impact from non-recurring items, is now expected to grow by 17-20%. In April 2004, the corresponding expectation for operating profit growth was around 15%

The increased expectation to operating profit growth in 2004 reflects a continued solid development in sales, supported by a sound overall development in costs. A changed phasing for some development projects will result in research and development costs growing at a somewhat lower rate than forecasted for reported sales.

Despite a continued challenging currency environment, the expectation for sales growth in 2004 measured in DKK remains around 10%, whereas operating profit now is expected to grow by slightly more than 5%.

Stock Exchange Announcement No 43 / 2004     Page 5 of 16
         
Novo Nordisk A/S

Investor Relations
Novo Allé
2880 Bagsværd

Denmark
Telephone:
+45 4444 8888

Telefax:
+45 4443 6633
Internet:
www.novonordisk.com
CVR Number:
24256790

 

   

For 2004 Novo Nordisk now expects a net financial income of DKK 100 million. This reflects the depreciation of especially the US dollar, since April 2004, which increases the expected positive impact from hedging of currencies, and an unchanged expectation of the negative impact from Novo Nordisk’s share of the financial results from associated companies.

For 2004 Novo Nordisk still expects the tax rate to be 33%, 1 percentage point lower than the tax rate realised in 2003.

Novo Nordisk continues to plan for capital expenditure of around DKK 3 billion in 2004. Depreciations, amortisation and impairment losses are still expected to be around DKK 1.8 billion and the free cash flow to be around DKK 3 billion.

Novo Nordisk has hedged expected net cash flows in relation to US dollars, Japanese yen and British pounds. The current currency hedging periods for these main currencies are 12, 11 and 8 months, respectively. The financial impact from currency hedging is included in `Net financials’.

All of the above expectations are provided that currency exchange rates remain at the current level for the rest of 2004.

Research and development update

The diabetes care segment

In July 2004 Novo Nordisk filed for marketing approval of NovoMix® 50 and NovoMix® 70 in Europe as well as for NovoMix® 50 in Japan. NovoMix® 50 and NovoMix® 70 are completing the Novo Nordisk portfolio of premix insulin analogues that provides a mix of both rapid-acting and intermediate-acting insulin effect. Upon approval, Novo Nordisk will be the only company providing the patients with a wide range of premix insulin analogues.

The findings from the 12-month interim analysis of the meal-related plasma glucose regulation for the AERx® iDMS project are currently being evaluated by Novo Nordisk and its partner Aradigm Corporation. To support the analysis it has been decided to add a pharmacokinetic and pharmacodynamic (PK/PD) study to the recently performed phase 3 safety study. The PK/PD study is expected to report in the first half of 2005. The design and completion of the remaining phase 3 clinical studies will depend upon the outcome of these analyses.

The biopharmaceuticals segment

Novo Nordisk continues to pursue the strategy for developing NovoSeven®into the preferred haemostatic agent for critical and life-threatening bleedings.

On 22 June 2004, Novo Nordisk announced that the results from a phase 2b study demonstrated that treatment with NovoSeven® of intracerebral haemorrhage patients led to a significant reduction in haemotoma growth. The key findings from the study were presented at the World Stroke Congress in Vancouver, Canada, in June. The optimal clinical and regulatory process for the use of NovoSeven® in connection with ICH is expected to be determined in collaboration with the regulatory authorities in Europe and the US in the second half of 2004.


Stock Exchange Announcement No 43 / 2004     Page 6 of 16
         
Novo Nordisk A/S

Investor Relations
Novo Allé
2880 Bagsværd

Denmark
Telephone:
+45 4444 8888

Telefax:
+45 4443 6633
Internet:
www.novonordisk.com
CVR Number:
24256790

 

   

Based on recent consultations with the European regulatory authorities regarding the approval process for the use of NovoSeven® in connection with trauma patients, Novo Nordisk expects to file for European approval of NovoSeven® in connection with blunt trauma. The filing will be supported by the existing data from the phase 2 study concluded in December 2003. Filing, which is expected in the first quarter of 2005, is earlier than previously anticipated and could lead to an approval for the trauma indication later in 2005.
Novo Nordisk expects to initiate a study on the use of NovoSeven® in connection with trauma within the next six months in the US, following consultations with the US regulatory authorities.

As part of the clinical expansion programme of the use of NovoSeven® in a surgical setting Novo Nordisk has initiated an exploratory phase 2a study focusing on the use of NovoSeven® in connection with spinal surgery.

Equity

Total equity was DKK 24,928 million at the end of the first half of 2004, equalling 72.8% of total assets, compared to 72.0% at the end of 2003. Please refer to appendix 5 for further elaboration hereof.

Holding of own shares

As per 11 August 2004, Novo Nordisk A/S and its wholly-owned affiliates owned 18,305,907 of its own B shares, corresponding to 5.16% of the total share capital.

Sustainable development

Novo Nordisk has reaffirmed its commitment as signatory to the UN Global Compact. At a ceremony in New York at the end of June 2004, a tenth principle was added to the UN Global Compact, specifying that `business should work against corruption in all its forms, including extortion and bribery’. Novo Nordisk reports annually on the company’s performance against the UN Global Compact, which covers human rights, labour and environment.

Legal issues update

On 2 June 2004 Novo Nordisk issued a press release in response to reports in Brazilian media according to which Novo Nordisk was one of several pharmaceutical companies being suspected of alleged illegal activities in relation to public tenders. Together with outside counsel Novo Nordisk has conducted an internal investigation regarding the alleged wrongdoings. It has been concluded, based on the information available, that neither the Brazilian affiliate nor its managers or employees have participated in any illegal acts or committed any wrongdoings. Meanwhile, the Federal Public Attorney in Sao Paulo has indicted two managers from the Brazilian affiliate. Novo Nordisk will support these managers in their defence in these cases.

In a pending lawsuit between Novo Nordisk and Bio-Technology General (Savient) / Teva, the US District Court in Delaware has ruled that Novo Nordisk’s `352 patent’ covering recombinant human growth hormone is invalid for lack of novelty, due to an error in the application process in the mid-80s. Novo Nordisk is currently considering an appeal of the US District Court decision.

Stock Exchange Announcement No 43 / 2004     Page 7 of 16
         
Novo Nordisk A/S

Investor Relations
Novo Allé
2880 Bagsværd

Denmark
Telephone:
+45 4444 8888

Telefax:
+45 4443 6633
Internet:
www.novonordisk.com
CVR Number:
24256790

 

   

Novo Nordisk’s US subsidiary, Novo Nordisk Pharmaceuticals, Inc, is, together with the majority of HRT manufacturers, defendants in a number of product liability lawsuits relating to HRT products. The products have been marketed in the US since 2000 and until July 2003, the products were sold and marketed by Pharmacia Corporation. The proceedings are currently in their preliminary stages; however, Novo Nordisk is not expecting the claims to impact Novo Nordisk’s financial outlook.

Conference call details

At 14:00 CET today, corresponding to 8:00 am New York time, a conference call will be held. Investors will be able to listen in via a link on novonordisk.com, which can be found under `Investors - Conference call’. Presentation material for the conference call will be made available approximately one hour before on the same page.

Forward-looking statement

The above sections contain forward-looking statements as the term is defined in the US Private Securities Litigation Reform Act of 1995. Forward-looking statements provide current expectations or forecasts of events such as new product introductions, product approvals and financial performance.

Such forward-looking statements are subject to risks, uncertainties and inaccurate assumptions. This may cause actual results to differ materially from expectations. Factors that may affect future results include interest rate and currency exchange rate fluctuations, delay or failure of development projects, production problems, unexpected contract breaches or terminations, government-mandated or market-driven price decreases for Novo Nordisk’s products, introduction of competing products, Novo Nordisk’s ability to successfully market both new and existing products, exposure to product liability and other lawsuits, changes in reimbursement rules and governmental laws and related interpretation thereof, and unexpected growth in costs and expenses.

Risks and uncertainties are further described in reports filed by Novo Nordisk with the US Securities and Exchange Commission (SEC) including the company’s Form 20-F, which was filed on 27 February 2004. Please also refer to the section `Management of risk in Novo Nordisk’ in the Annual Financial Report 2003. Novo Nordisk is under no duty to update any of the forward-looking statements or to conform such statements to actual results, unless required by law.

Bagsværd 11 August 2004
The Board of Directors

Stock Exchange Announcement No 43 / 2004     Page 8 of 16
         
Novo Nordisk A/S

Investor Relations
Novo Allé
2880 Bagsværd

Denmark
Telephone:
+45 4444 8888

Telefax:
+45 4443 6633
Internet:
www.novonordisk.com
CVR Number:
24256790

 

   

Contacts for further information

Media:

Investors:

   

Outside North America:

Outside North America:

Mike Rulis

Peter Haahr

Tel (direct): (+45) 4442 3573 Tel (direct): (+45) 4442 1207

e-mail: mike@novonordisk.com

e-mail: pehr@novonordisk.com

   
  Palle Holm Olesen
  Tel (direct): (+45) 4442 6175
  e-mail: phoo@novonordisk.com
   
In North America: In North America:
Susan T Jackson Christian Kanstrup
Tel (direct): (+1) 609 919 7776 Tel (direct): (+1) 609 919 7937
e-mail: stja@novonordisk.com e-mail: cka@novonordisk.com


Further information on Novo Nordisk is available on the company’s internet homepage at the address: novonordisk.com

Stock Exchange Announcement No 43 / 2004     Page 9 of 16
         
Novo Nordisk A/S

Investor Relations
Novo Allé
2880 Bagsværd

Denmark
Telephone:
+45 4444 8888

Telefax:
+45 4443 6633
Internet:
www.novonordisk.com
CVR Number:
24256790

 

   

Appendix 1:

The Novo Nordisk Group
Quarterly numbers in DKK

(Amounts in DKK million, except number of employees, earnings per share and number of shares outstanding.)

  2004   2003 % change
Q22003 -
  Q2 Q1   Q4 Q3 Q2 Q1 Q2 2004
 
 
 
Sales 7,222   6,567      7,158   6,655   6,477   6,056   12%
                           
Gross profit 5,280   4,716     5,031   4,847   4,677   4,390   13%
Gross margin 73.1 % 71.8 %   70.3 % 72.8 % 72.2 % 72.5 %
                           
Sales and distribution costs 2,037   1,926     2,097   1,880   1,854   1,772   10%
Percent of sales 28.2 % 29.3 %   29.3 % 28.2 % 28.6 % 29.3 %
Research and development costs 978   1,035     1,125   1,012   969   937   1%
Percent of sales 13.5 % 15.8 %   15.7 % 15.2 % 15.0 % 15.5 %
Administrative expenses 425   471     482   485   415   455   2%
Percent of sales 5.9 % 7.2 %   6.7 % 7.3 % 6.4 % 7.5 %
Licence fees and other operating income (net) 71   232     423   216   226   171   -69%
                           
Operating profit 1,911   1,516     1,750   1,686   1,665   1,397   15%
Operating margin 26.5 % 23.1 %   24.4 % 25.3 % 25.7 % 23.1 %
                           
Share of profit in associated R&D companies (44 ) (38 )   78   (45 ) (41 ) (63 ) 7%
Share of profit in other associated companies 4   (31 )   7   (2 ) (2 ) 9   -300%
Financial income 104   178     438   177   446   421   -77%
Financial expenses 44   22     117   103   116   133   -62%
Profit before taxation 1,931   1,603     2,156   1,713   1,952   1,631   -1%
                           
Net profit 1,293   1,074     1,413   1,128   1,288   1,073   0%
                           
Depreciation, amortisation and impairment losses 387   380     553   363   356   309   9%
Capital expenditure 642   392     934   383   519   466   24
Cash flow from operating activities 1,710   1,350     221   2,317   1,437   2,174   19%
Free cash flow 956   886     (703 ) 1,932   910   1,707   5%
                           
Equity 24,928   24,048     24,887   23,700   22,807   21,829   9%
Total assets 34,248   33,838     34,564   35,140   33,103   31,382   3%
Equity ratio 72.8 % 71.1 %   72.0 % 67.4 % 68.9 % 69.6 %
                           
Full-time employees at the end of the period 19,631   19,179     18,756   18,664   18,465   18,221   6%
                           
Diluted earnings per share (in DKK)* 3.81   3.16     4.17   3.31   3.76   3.11   1%
Average number of shares outstanding (million)*
- used for diluted earnings per share
339.8   339.8     339.1   340.7   342.0   344.6  
 
Sales by business segments:
   Insulin analogues 1,045   893     796   711   576   488   81%
   Human insulin and insulin-related sales 3,669   3,232     3,963   3,554   3,666   3,414   0%
   Oral antidiabetic products (OAD) 382   419     390   387   300   363   27%
   Diabetes care total 5,096   4,544     5,149   4,652   4,542   4,265   12%
                           
   NovoSeven® 1,093   1,027     940   1,010   996   925   10%
   Growth hormone therapy 562   554     588   520   537   503   5%
   Hormone replacement therapy 392   342     399   361   292   279   34%
   Other products 79   100     82   112   110   84   -28%
   Biopharmaceuticals total 2,126   2,023     2,009   2,003   1,935   1,791   10%
 
Sales by geographic segments:
   Europe 3,118   2,894     3,165   2,920   2,935   2,723   6%
   North America 1,882   1,769     1,618   1,674   1,501   1,566   25%
   International Operations 1,135   980     1,234   1,027   1,058   910   7%
   Japan & Oceania 1,087   924     1,141   1,034   983   857   11%
 
Segment operating profit:
   Diabetes care 954   693     966   755   784   691   22%
   Biopharmaceuticals 957   823     784   931   881   706   9%

*) For Q2 2004 diluted earnings per share/ADR of a nominal value of DKK 2, which include options on Novo Nordisk’s treasury shares with an exercise price below current market value, have been based on an average number of shares of 339,780,374.

 

Stock Exchange Announcement No 43 / 2004     Page 10 of 16
         
Novo Nordisk A/S

Investor Relations
Novo Allé
2880 Bagsværd

Denmark
Telephone:
+45 4444 8888

Telefax:
+45 4443 6633
Internet:
www.novonordisk.com
CVR Number:
24256790

 

   

Appendix 2:

The Novo Nordisk Group
Quarterly numbers in EUR
(Amounts in EUR million, except number of employees, earnings per share and number of shares outstanding.)
Key figures are translated into EUR as supplementary information - the translation is based on average exchange rate for income statement and exchange rate at the balance sheet date for balance sheet items.

  2004   2003 % change
Q2 2003 -
  Q2   Q1     Q4   Q3   Q2   Q1   Q2 2004
 
 
 
Sales 970   882      957   896   872   815   12%
                             
Gross profit 710   633     673   652   630   591   13%
Gross margin 73.1 % 71.8 % 70.3 % 72.8 % 72.2 % 72.5 %
                             
Sales and distribution costs 273   259     281   253   250   238   10%
Percent of sales 28.2 % 29.3 % 29.3 % 28.2 % 28.6 % 29.3 %
Research and development costs 131   139     150   136   131   126   1%
Percent of sales 13.5 % 15.8 % 15.7 % 15.2 % 15.0 % 15.5 %
Administrative expenses 60   62     64   66   55   62   2%
Percent of sales 5.9 % 7.2 % 6.7 % 7.3 % 6.4 % 7.5 %
Licence fees and other operating income (net) 10   31     56   30   30   23   -69%
                             
Operating profit 256   204   234   227   224   188   15%
Operating margin 26.5 % 23.1 % 24.4 % 25.3 % 25.7 % 23.1 %
                             
Share of profit in associated R&D companies (4 ) (6 )   10   (6 ) (6 ) (8 ) 7%
Share of profit in other associated companies -   (4 )   1   -   -   1   -300%
Financial income 14   24     59   23   60   57   -77%
Financial expenses 6   3     16   13   16   18   -62%
Profit before taxation 260   215     288   231   262   220   -1%
                             
Net profit 174   144   189   152   174   144   0%
                             
Depreciation, amortisation and impairment losses 52   51     74   48   48   42   9%
Capital expenditure 86   53     125   51   70   63   24%
Cash flow from operating activities 230   181     28   312   193   293   19%
Free cash flow 128   119     (96 ) 260   123   230   5%
                             
Equity 3,348   3,230     3,343   3,192   3,070   2,939   9%
Total assets 4,600   4,545     4,643   4,732   4,455   4,226   3%
Equity ratio 72.8 % 71.1 % 72.0 % 67.4 % 68.9 % 69.6 %
                             
Full-time employees at the end of the period 19,631   19,179     18,756   18,664   18,465   18,221   6%
                             
Diluted earnings per share (in EUR)* 0.52   0.42     0.56   0.45   0.50   0.42   1%
Average number of shares outstanding (million)*
- used for diluted earnings per share
339.8   339.8     339.1   340.7   342.0   344.6  
 
Sales by business segments:
   Insulin analogues 140   120     106   96   77   66   81%
   Human insulin and insulin-related sales 491   435     529   479   494   459   0%
   Oral antidiabetic products (OAD) 52   56     53   52   40   49   27%
   Diabetes care total 683   611   688   627   611   574   12%
                             
   NovoSeven® 147   138     125   136   135   124   10%
   Growth hormone therapy 76   74     79   70   72   68   5%
   Hormone replacement therapy 53   46     54   48   39   38   34%
   Other products 11   13     11   15   15   11   -28%
   Biopharmaceuticals total 287   271   269   269   261   241   10%
 
Sales by geographic segments:
   Europe 419   389     422   394   394   367   6%
   North America 253   237     217   225   202   211   25%
   International Operations 152   132     165   138   143   122   7%
   Japan & Oceania 146   124     153   139   133   115   11%
 
Segment operating profit:
   Diabetes care 128   93     129   101   106   93   22%
   Biopharmaceuticals 128   111     105   126   118   95   9%

*) For Q2 2004 diluted earnings per share/ADR of a nominal value of DKK 2, which include options on Novo Nordisk’s treasury shares with an exercise price below current market value, have been based on an average number of shares of 339,780,374.

 

Stock Exchange Announcement No 43 / 2004     Page 11 of 16
         
Novo Nordisk A/S

Investor Relations
Novo Allé
2880 Bagsværd

Denmark
Telephone:
+45 4444 8888

Telefax:
+45 4443 6633
Internet:
www.novonordisk.com
CVR Number:
24256790

 

   

Appendix 3:

As of 1 January 2004, the accounting policies have been changed to comply with International Financial Reporting Standards (IFRS). The accounting policies used in appendix 1 as well as all other appendices in this interim report are consistent with those used in the Annual Financial Report 2003 except for the changes described in the section ‘Adoption of IFRS in 2004’ in the Annual Financial Report 2003, which describes the changes from the historically applied Danish GAAP to IFRS.

The Novo Nordisk Group
Consolidated income statement

DKK million H1
2004
  H1
2003
  Q2
2004
  Q2
2003
 

 
 
Sales 13,789   12,533   7,222   6,477  
Cost of goods sold 3,793   3,466   1,942   1,800  

 
 
Gross profit 9,996   9,067   5,280   4,677  
                 
Sales and distribution costs 3,963   3,626   2,037   1,854  
Research and development costs 2,013   1,906   978   969  
Administrative expenses 896   870   425   415  
Licence fees and other operating income (net) 303   397   71   226  

 
 
Operating profit 3,427   3,062   1,911   1,665  
                 
Share of profit in associated R&D companies (82 ) (104 ) (44 ) (41 )
Share of profit in other associated companies (27 ) 7   4   (2 )
Financial income 282   867   104   446  
Financial expenses 66   249   44   116  

 
 
Profit before taxation 3,534   3,583   1,931   1,952  
                 
Income taxes 1,167   1,222   638   664  

 
 
NET PROFIT 2,367   2,361   1,293   1,288  
                 
Earnings per share (DKK) 7.00   6.89   3.82   3.77  
Earnings per share diluted (DKK) 6.97   6.87   3.81   3.76  
 
Segment sales:
   Diabetes care 9,640   8,807   5,096   4,542  
   Biopharmaceuticals 4,149   3,726   2,126   1,935  
 
Segment operating profit:
   Diabetes care 1,647   1,475   954   784  
   Biopharmaceuticals 1,780   1,587   957   881  

 

Stock Exchange Announcement No 43 / 2004     Page 12 of 16
         
Novo Nordisk A/S

Investor Relations
Novo Allé
2880 Bagsværd

Denmark
Telephone:
+45 4444 8888

Telefax:
+45 4443 6633
Internet:
www.novonordisk.com
CVR Number:
24256790

 

   

Appendix 4:

The Novo Nordisk Group
Consolidated balance sheet

DKK million 30 Jun 2004 31 Dec 2003 30 Jun 2003

ASSETS      
Long-term assets            
Intangible assets 410   331   371  
Property, plant and equipment 16,682   16,342   16,011  
Investments in associated companies 958   1,040   1,076  
Deferred tax assets 532   579   553  
Long-term financial assets 113   80   54  
TOTAL LONG-TERM ASSETS 18,695   18,372   18,065  
 
Current assets
Inventories 7,079   6,531   6,423  
Trade receivables 3,834   3,785   3,514  
Tax receivables 52   134   497  
Other receivables 2,048   2,652   1,839  
Marketable securities 525   1,828   216  
Cash at bank and in hand 2,015   1,262   2,549  
TOTAL CURRENT ASSETS 15,553   16,192   15,038  
             

TOTAL ASSETS 34,248   34,564   33,103  

             
EQUITY AND LIABILITIES
             
Share capital 709   709   709  
Treasury shares (36 ) (33 ) (28 )
Share premium account 2,565   2,565   2,565  
Retained earnings 21,538   21,037   19,122  
Other comprehensive income 152   609   439  

TOTAL EQUITY 24,928   24,887   22,807  

 
Long-term liabilities
Long-term debt 716   753   1,276  
Deferred tax liabilities 1,576   1,610   1,289  
Provision for pensions 275   222   300  
Other long-term provisions 73   60   39  

Total long-term liabilities 2,640   2,645   2,904  
 
Current liabilities
Short-term debt 502   975   706  
Trade payables 813   1,008   736  
Tax payables 270   643   1,365  
Other current liabilities 3,887   3,366   3,609  
Other short-term provisions 1,208   1,040   976  

Total current liabilities 6,680   7,032   7,392  
             
TOTAL LIABILITIES 9,320   9,677   10,296  
             

TOTAL EQUITY AND LIABILITIES 34,248   34,564   33,103  

 

Stock Exchange Announcement No 43 / 2004     Page 13 of 16
         
Novo Nordisk A/S

Investor Relations
Novo Allé
2880 Bagsværd

Denmark
Telephone:
+45 4444 8888

Telefax:
+45 4443 6633
Internet:
www.novonordisk.com
CVR Number:
24256790

 

   

Appendix 5:

The Novo Nordisk Group
Consolidated statement of changes in equity

                  Other comprehensive income
     
DKK million Share
capital
  Treasury
shares
  Share
premium
account
  Retained
earnings
  Exchange
rate
adjustments
  Deferred
gain/loss
on cash
flow
hedges
  Other
adjustments
  Total

H1 2004                
                             
Balance at the beginning of the year 709     (33 ) 2,565     21,037    33    513    63   24,887
                             
Net profit for the period             2,367               2,367
Purchase of treasury shares     (3 )     (425 )             (428 )
Sale of treasury shares     -       47               47
Dividends declared             (1,488 )             (1,488 )
Exchange rate adjustment of investments in subsidiaries                 (18 )         (18 )
Reversal of deferred (gain)/loss on cash flow hedges at the
    beginning of the year
                    (513 )     (513 ) 
Deferred gain/(loss) on cash flow hedges at the end
    of the period
                    77       77
Other adjustments                         (3 ) (3 )

Balance at the end of the period 709   (36 ) 2,565   21,538   15   77   60   24,928  
                                 
H1 2003                                
Balance at the beginning of the year 709   (19 ) 2,565   18,968   27   391   (45 ) 22,596
                             
Net profit for the period             2,361               2,361
Purchase of treasury shares     (9 )     (973 )             (982 )
Sale of treasury shares     -       9               9
Dividends declared             (1,243 )             (1,243 )
Exchange rate adjustment of investments in subsidiaries                 (14 )         (14 )
Reversal of deferred (gain)/loss on cash flow hedges at the
    beginning of the year
                    (391 )     (391 )
Deferred gain/(loss) on cash flow hedges at the end
    of the period
                    461       461
Other adjustments                         10   10

Balance at the end of the period 709   (28 ) 2,565   19,122   13   461   (35 ) 22,807

 

Stock Exchange Announcement No 43 / 2004     Page 14 of 16
         
Novo Nordisk A/S

Investor Relations
Novo Allé
2880 Bagsværd

Denmark
Telephone:
+45 4444 8888

Telefax:
+45 4443 6633
Internet:
www.novonordisk.com
CVR Number:
24256790

 

   

Appendix 6:

The Novo Nordisk Group
Condensed consolidated statements of cash flow and financial resources

DKK million H1 2004 H1 2003

Net profit 2,367   2,361  
         
Net reversals with no effect on cash flow 2,367   2,032  
Income taxes paid and net interest received (1,311 ) (484 )

Cash flow before change in working capital 3,423   3,909  
         
Net change in working capital (363 ) (298 )

Cash flow from operating activities 3,060   3,611  
         
Net investments in intangible assets and long-term financial assets (184 ) (9 )
Capital expenditure for property, plant and equipment (1,034 ) (985 )
Net change in marketable securities (>3 months) 1,304   101  

Total cash flow from investing activities 86   (893 )
         
Cash flow from financing activities (2,202 ) (1,760 )
         
NET CASH FLOW 944   958  
         
Unrealised gain/(loss) on exchange rates in cash and cash equivalents (16 ) (11 )

Net change in cash and cash equivalents 928   947  
         
Cash and cash equivalents at the beginning of the year 841   919  

Cash and cash equivalents at the end of the period 1,769   1,866  
         
Undrawn committed credit facilities 6,689   8,966  

FINANCIAL RESOURCES AT THE END OF THE PERIOD 8,458   10,832  
         
FREE CASH FLOW* 1,842   2,617  

*) Cash flow from operating activities + Cash flow from investing activities - Net change in marketable securities (>3 months)

 

Stock Exchange Announcement No 43 / 2004     Page 15 of 16
         
Novo Nordisk A/S

Investor Relations
Novo Allé
2880 Bagsværd

Denmark
Telephone:
+45 4444 8888

Telefax:
+45 4443 6633
Internet:
www.novonordisk.com
CVR Number:
24256790

 

   

Appendix 7:

The Novo Nordisk Group
Reconciliations of Danish GAAP to IFRS

Accounting policies

This unaudited interim financial report has been prepared in accordance with International Accounting Standard 34 on Interim Financial Reporting.

As of 1 January 2004, the accounting policies have been changed to comply with International Financial Reporting Standards (IFRS). The date of transition is 1 January 2002. The accounting policies used in this interim financial report are consistent with those used in the Annual Financial Report 2003 except for the changes described in the section ‘Adoption of IFRS in 2004’ in the Annual Financial report 2003, which describes the changes from the historically applied Danish GAAP to IFRS. In this interim financial report the presentation and accounting terminology comply with IFRS.

The reconciliation items in the tables below refer to descriptions of the changes in accounting policies due to IFRS adoption mentioned in the section ‘Adoption of IFRS in 2004’ in the Annual Financial Report 2003.

Effect of IFRS adoption for the quarterly financial reporting in 2003

DKK Million Q1   Q2   Q3   Q4  

Operating profit - Danish GAAP 1,320   1,619   1,636   1,809  
    Accounting for associated R&D companies - reclass. of share of profit or loss 40   36   40   31  
    Accounting for associated R&D companies - reclass. of capital (gain)/loss 18   -   -   (103 )
    Provisions for pensions 9   -   1   --  
    Borrowing costs - depreciation 10   9   9   10  
    Other -   1   -   3  
Operating profit - IFRS 1,397   1,665   1,686   1,750  
                 
Net profit - Danish GAAP 1,091   1,286   1,130   1,351  
    Accounting for associated R&D companies (5 ) (5 ) (5 ) 6  
    Market value of currency options (15 ) 17   (13 ) 41  
    Provisions for pensions 5   -   1   -  
    Borrowing costs - depreciation 10   9   9   10  
    Borrowing costs - interest expenses as incurred (3 ) (3 ) (2 ) (2 )
    Other (10 ) (16 ) 8   7  
Net profit - IFRS 1,073   1,288   1,128   1,413  
                 
Equity - Danish GAAP 22,158   23,159   24,037   25,224  
    Accounting for associated R&D companies 40   34   28   31  
    Market value of currency options (16 ) (23 ) (18 ) (35 )
    Provisions for pensions (32 ) (30 ) (29 ) (36 )
    Borrowing costs (282 ) (278 ) (273 ) (268 )
    Other (39 ) (55 ) (45 ) (29 )
Equity - IFRS 21,829   22,807   23,700   24,887  
                 
Effect of IFRS adoption on net profit                
                 
DKK Million     2003 2002      

   
Net profit - Danish GAAP 4,858 4,095      
    Accounting for associated R&D companies     (9 ) (9 )    
    Market value of currency options     30   50      
    Provisions for pensions     6   (7 )    
    Borrowing costs - depreciation     38   39      
    Borrowing costs - interest expenses as incurred     (10 ) (14 )    
    Other     (11 ) (10 )    
Net profit - IFRS 4,902 4,144      
                 
Effect of IFRS adoption on equity                
                 
DKK Million     31 Dec
2003
31 Dec
2002
1Jan
2002
 

Equity - Danish GAAP 25,224 22,928 20,137
    Accounting for associated R&D companies     31   47   57  
    Market value of currency options     (35 ) (22 ) (22 )
    Provisions for pensions     (36 ) (42 ) (15 )
    Borrowing costs     (268 ) (287 ) (297 )
    Other                                                                                                             (29 ) (28 ) (31  )
Equity - IFRS 24,887 22,596 19,829

Stock Exchange Announcement No 43 / 2004     Page 16 of 16
         
Novo Nordisk A/S

Investor Relations
Novo Allé
2880 Bagsværd

Denmark
Telephone:
+45 4444 8888

Telefax:
+45 4443 6633
Internet:
www.novonordisk.com
CVR Number:
24256790