Ownership Submission
FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Cherevka Holli
 2. Date of Event Requiring Statement (Month/Day/Year)
09/19/2017		 3. Issuer Name and Ticker or Trading Symbol
Ampio Pharmaceuticals, Inc. [AMPE]
(Last)
(First)
(Middle)
C/O AMPIO PHARMACEUTICALS, INC., 373 INVERNESS PARKWAY, SUITE 200		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Chief Operating Officer
 5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

ENGLEWOOD, CO 80112		 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (Right to Buy)   (1) 01/14/2023 Common Stock 35,000 $ 4.16 D  
Stock Option (Right to Buy)   (2) 04/02/2023 Common Stock 45,000 $ 4.72 D  
Stock Option (Right to Buy)   (3) 11/08/2023 Common Stock 80,000 $ 8.62 D  
Stock Option (Right to Buy)   (4) 10/06/2024 Common Stock 30,000 $ 3.43 D  
Stock Option (Right to Buy)   (5) 07/15/2026 Common Stock 170,000 $ 1.03 D  
Stock Option (Right to Buy)   (6) 08/08/2026 Common Stock 30,000 $ 0.51 D  
Stock Option (Right to Buy)   (7) 09/19/2027 Common Stock 200,000 $ 0.55 D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Cherevka Holli
C/O AMPIO PHARMACEUTICALS, INC.
373 INVERNESS PARKWAY, SUITE 200
ENGLEWOOD, CO 80112		       Chief Operating Officer  

Signatures

/s/ Holli Cherevka 09/21/2017
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The Stock Options vested and became exercisable in four installments. 1/4th of the options vested on the grant date of January 14, 2013, 1/4 th of the options vested on January 14, 2014, 1/4th of the options vested on January 14, 2015 and 1/4th of the options vested on January 14, 2016.
(2) The Stock Options vested and became exercisable in four installments. 1/4th of the options vested on the grant date of April 2, 2013, 1/4 th of the options vested on January 14, 2014, 1/4th of the options vested on January 14, 2015 and 1/4th of the options vested on January 14, 2016.
(3) The Stock Options vested and became exercisable monthly over 36 months in equal installments.
(4) The Stock Options vested and became exercisable in two installments. 1/2 of the options vested on the grant date of October 6, 2014, and 1/2th of the options vested on October 6, 2015.
(5) The Stock Options vest and become exercisable in three installments. 1/3rd of the options vested on the grant date of July 15, 2016, 1/3rd of the options vested on July 15, 2017 and 1/3rd of the options vest on July 15, 2018.
(6) The Stock Options vest and become exercisable immediately.
(7) The Stock Options vest and become exercisable in two equal installments. 1/2 of the options vested on the grant date of September 19, 2017; and the additional 1/2 of the options shall vest on September 19, 2018.

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