Edgar Filing: NANOBAC PHARMACEUTICALS INC

Unassociated Document

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

____________________

FORM 10-QSB

QUARTERLY REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

____________________

For the Quarter Period Ended

March 31, 2006

_______________________

Nanobac Pharmaceuticals, Incorporated

(Exact name of registrant as specified in its charter)

Florida	0-24696	59-3248917
(State or Other Jurisdiction of Incorporation)	(Commission File Number)	(I.R.S. Employer Identification Number)

4730 North Habana Avenue, Suite 205, Tampa, Florida 33614

(Address of Principal Executive Office) (Zip Code)

(813) 264-2241

(Registrant’s telephone number, including area code)

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for a shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.

Yes x No o

Indicate by check mark whether the Registrant is an accelerated filer (as defined in Rule 12b-2 of the Act):

Yes o No x

The number of shares issued and outstanding of the Registrant’s Common Stock, no par value, as of May 8, 2006 was 193,506,760.

NANOBAC PHARMACEUTICALS, INCORPORATED AND SUBSIDIARIES

PART I - FINANCIAL INFORMATION

Item 1: Financial Statements

Condensed Consolidated Balance Sheets as of March 31, 2006 (unaudited) and December 31, 2005	3

Condensed Consolidated Statements of Operations for the three months ended March 31, 2006 and 2005 (unaudited)	4

Condensed Consolidated Statement of Stockholders' Equity for the three months ended March 31, 2006 (unaudited)	5

Condensed Consolidated Statements of Cash Flows for the three months ended March 31, 2006 and 2005 (unaudited)	6

Notes to the Condensed Consolidated Financial Statements	7


Item 2: Management’s Discussion and Analysis of Financial Condition and Results of Operations	10

Item 3: Controls and Procedures	19

PART II - OTHER INFORMATION

Item 1: Legal Proceedings	19

Item 2: Unregistered Sales of Equity Securities and Use of Proceeds	20

Item 3: Defaults Upon Senior Securities	21

Item 4: Submission of Matters to a Vote of Security Holders	21

Item 5: Other Information	21

Item 6: Exhibits	21

NANOBAC PHARMACEUTICALS, INCORPORATED AND SUBSIDIARIES

CONDENSED CONSOLIDATED

BALANCE SHEETS

	(Unaudited)
	March 31, 2006			December 31, 2005
ASSETS
CURRENT ASSETS
Cash	$	626,005		$	8,975
Account receivable		12,997			3,283
Inventory		109,191			117,280
Prepaid expenses		40,554			43,725
Total current assets		788,747			173,263

FURNITURE AND EQUIPMENT, less accumulated depreciation
of $83,764 at March 31, 2006 and $131,163 at
December 31, 2005		74,886			106,952

OTHER ASSETS
Security deposits		23,521			20,695
Intangible assets, less accumulated amortization
of $951,351 at March 31, 2006 and $1,539,621 at
December 31, 2005		4,291,691			5,053,421
Goodwill		3,615,393			3,615,393
Total other assets		7,930,605			8,689,509

TOTAL ASSETS	$	8,794,238		$	8,969,724

LIABILITIES AND STOCKHOLDERS' EQUITY
CURRENT LIABILITIES
Accounts payable	$	272,241		$	313,932
Accrued compensation		391,740			462,658
Accrued expenses		487,831			376,874
Short-term notes payable		14,675			50,843
Other liabilities		21,121			29,425
Related party loans		3,676,974			2,434,733
Total current liabilities		4,864,582			3,668,465

LONG-TERM LIABILITIES
Stock settlement obligation		2,836,538			2,836,538
Total liabilities		7,701,120			6,505,003

COMMITMENTS AND CONTINGENCIES		-			-

STOCKHOLDERS' EQUITY
Preferred stock, no par value, 1,000,000 shares authorized,
no shares issued and outstanding		-			-
Common stock, no par value, 250,000,000 shares authorized,
2006, 193,506,760 shares issued and outstanding		16,428,550
2005, 189,006,760 shares issued and outstanding					16,307,050
Additional paid-in capital		3,503,681			3,503,681
Accumulated deficit		(18,868,222	)		(17,380,535	)
Accumulated other comprehensive income		29,109			34,525
Total stockholders' equity		1,093,118			2,464,721

TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY	$	8,794,238		$	8,969,724

The accompanying notes are an integral part of these financial statements.

NANOBAC PHARMACEUTICALS, INCORPORATED AND SUBSIDIARIES

CONDENSED CONSOLIDATED

STATEMENTS OF OPERATIONS

(UNAUDITED)

	Three Months			Three Months
	ended			ended
	March 31, 2006			March 31, 2005
				(Restated)
REVENUE (Note 3)	$	161,286		$	151,865

COST OF REVENUE		45,195			43,838

GROSS PROFIT		116,091			108,027

OPERATING EXPENSES
Selling, general and administrative		425,870			341,023
Research and development		354,322			346,057
Impairment loss on intangible asset		585,000			-
Depreciation and amortization		188,217			188,252
Total Operating Expenses		1,553,409			875,332

OPERATING LOSS		(1,437,318	)		(767,305	)

OTHER INCOME (EXPENSES)
Interest expense		(38,239	)		(5,193	)
Loss on stock settlement obligation		-			(717,908	)
Other, net		(12,130	)		(15,515	)

LOSS FROM CONTINUING OPERATIONS
BEFORE INCOME TAXES		(1,487,687	)		(1,505,921	)

PROVISION FOR INCOME TAXES		-			-


NET LOSS	$	(1,487,687	)	$	(1,505,921	)


LOSS PER COMMON SHARE
Basic and Diluted	$	(0.01	)	$	(0.01	)

WEIGHTED AVERAGE NUMBER OF
COMMON SHARES OUTSTANDING
Basic and Diluted		191,232,034			188,394,671

The accompanying notes are an integral part of these financial statements.

NANOBAC PHARMACEUTICALS, INCORPORATED AND SUBSIDIARIES

CONDENSED CONSOLIDATED

STATEMENT OF CHANGES IN STOCKHOLDERS' EQUITY

FOR THE THREE MONTHS ENDED MARCH 31, 2006

(UNAUDITED)

													Accumulated
					Additional					Other			Other
	Common Stock				Paid-in		Accumulated			Comprehensive			Comprehensive
	Shares		Value		Capital		Deficit			Loss			Income			Total


Balance, December 31, 2005		189,006,760	$	16,307,050	$	3,503,681		($17,380,535	)				$	34,525		$	2,464,721

Stock issued for services		4,500,000		121,500		-		-			-			-			121,500

Comprehensive loss:
Net loss		-		-		-		(1,487,687	)		($1,487,687	)					(1,487,687	)
Foreign currency translation
adjustment		-		-		-		-			(5,416	)		(5,416	)		(5,416	)

Comprehensive loss											($1,493,103	)


Balance, March 31, 2006		193,506,760	$	16,428,550	$	3,503,681	$	(18,868,222	)				$	29,109		$	1,093,118

The accompanying notes are an integral part of these financial statements.

NANOBAC PHARMACEUTICALS, INCORPORATED AND SUBSIDIARIES

CONDENSED CONSOLIDATED

STATEMENTS OF CASH FLOWS

(UNAUDITED)

	Three Months			Three Months
	ended			ended
	March 31, 2006			March 31, 2005
CASH FLOWS FROM OPERATING ACTIVITIES				(Restated)
Net loss	$	(1,487,687	)	$	(1,505,921	)
Adjustments to reconcile net loss to cash
flows from operating activities:
Depreciation and amortization		188,217			188,252
Impairment loss on intangible assets		585,000			-
Loss on disposition of fixed assets		18,330			-
Loss on stock settlement obligation		-			717,908
Charges for common stock issued for services		-			10,500
Interest expense accrued for stockholder loan		38,023			3,895
Net (increase) decrease in assets:
Accounts receivable		(9,714	)		(13,334	)
Inventory		8,089			(3,860	)
Other assets		3,171			(5,158	)
Net increase (decrease) in liabilities:
Accounts payable		(41,691	)		(16,172	)
Accrued compensation		50,582			21,458
Accrued expenses		110,957			(18,818	)
Deferred revenue		(8,304	)		1,762
Total adjustments		942,660			886,433
Net cash flows from operating activities		(545,027	)		(619,488	)

CASH FLOWS FROM INVESTING ACTIVITIES
Acquisition of furniture and equipment		(3,825	)		(33,868	)
Proceeds from sale of furniture and equipment		6,547			-
Payment of security deposits		(2,731	)		-
Net cash flows from investing activities		(9	)		(33,868	)

CASH FLOWS FROM FINANCING ACTIVITIES
Proceeds from issuance of common stock
pursuant to subscription agreements		-			200,000
Stock issuance costs		-			(25,000	)
Proceeds from stockholder loans, net		1,204,218			448,883
Proceeds from notes payable		2,601			30,907
Payment of notes payable		(39,000	)		(16,079	)
Net cash flows from financing activities		1,167,819			638,711

Effect of exchange rate changes		(5,753	)		10,316

Net change in cash		617,030			(4,329	)
Cash balance, beginning of year		8,975			17,908
Cash balance, end of period	$	626,005		$	13,579

Supplemental disclosures of cash flow information:
Cash paid for interest	$	216		$	1,298

Supplemental schedule of non-cash investing and financing activities:
Common stock issued in exchange for current liabilities	$	121,500		$	-

The accompanying notes are an integral part of these financial statements.

NANOBAC PHARMACEUTICALS, INCORPORATED AND SUBSIDIARIES

NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

THREE MONTHS ENDED MARCH 31, 2006

(UNAUDITED)

1. Nature of operations and summary of significant accounting polices

Nature of business

Nanobac Pharmaceuticals, Incorporated and subsidiaries, ("Nanobac”, the "Company", or "NNBP") trades under the symbol "NNBP."

NNBP’s primary business is research and development of therapeutic and diagnostic technologies related to nanobacterium sanguineum (“Nanobacteria”). Nanobacteria are believed to be small, calcifying nano-particles that can be found in human blood, kidney stones and arterial wall plaques.

Principles of Consolidation

The consolidated financial statements include the accounts of the Company and its wholly-owned subsidiaries, Nanobac Sciences LLC, Nanobac OY and Nanobac Research Institute LLC. All intercompany transactions and balances have been eliminated in consolidation.

Basis of Presentation

In the opinion of management, the accompanying financial statements include all adjustments, consisting only of normal recurring items, necessary for their fair presentation in conformity with accounting principles generally accepted in the United States of America. The results of operations for the three months ended March 31, 2006 are not necessarily indicative of the results for a full year.

The financial statements for the period ended March 31, 2006 and notes thereto should be read in conjunction with the financial statements and notes thereto for the year ended December 31, 2005 for the Company as filed in the annual report on Form 10-KSB, which information is included herein by reference.

Liquidity and Management Plans

The accompanying financial statements have been prepared assuming that the Company will continue as a going concern. The Company has incurred recurring losses and has a working capital deficiency at March 31, 2006. The Company is dependent on continued financing from outside investors including additional shareholder loans. All of these matters raise substantial doubt about the ability of the Company to continue as a going concern. Management believes that the Company will need to raise additional capital in order to launch new clinical trials, fund research and development for new treatment areas, and general working capital requirements. Capital may be raised through further sales of equity securities, which may result in dilution of the position of current shareholders. At this time, there is no firm commitment to invest in NNBP.

There can be no assurances that NNBP will be successful in obtaining debt or equity financing in order to achieve its financial objectives and continue as a going concern. The financial statements do not include any adjustments to the carrying amount of assets and the amounts and classifications of liabilities that might result from an adverse outcome of this uncertainty.

NANOBAC PHARMACEUTICALS, INCORPORATED AND SUBSIDIARIES

NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

THREE MONTHS ENDED MARCH 31, 2006

(UNAUDITED)

1. Nature of operations and summary of significant accounting polices (continued)

Impairment of long-lived assets and intangible assets

In accordance with Statement of Financial Accounting Standards No. 142, “Goodwill and Other Intangible Assets” (“SFAS No. 142”), and Statement of Financial Accounting Standards, No. 144, “Accounting for the Impairment or Disposal of Long-Lived Assets” (“SFAS No. 144”), the Company reviews its non-amortizable long-lived assets, including intangible assets and goodwill for impairment annually, or sooner whenever events or changes in circumstances indicate the carrying amounts of such assets may not be recoverable. Other depreciable or amortizable assets are reviewed when indications of impairment exist. Upon such an occurrence, recoverability of these assets is determined as follows. For long-lived assets that are held for use, the Company compares the forecasted undiscounted net cash flows to the carrying amount. If it is determined that the long-lived asset will be unable to recover its carrying amount, then it is written down to fair value. For long-lived assets held for sale, assets are written down to fair value. Fair value is determined based on discounted cash flows or appraised values from management’s estimates, depending upon the nature or the assets. Impairment of goodwill is tested using a two step method. The first step is to compare the fair value of the reporting unit to its book value, including goodwill. If the fair value of the unit is less than its book value, the Company then determines the implied fair value of goodwill by deducting the fair value of the reporting unit’s net assets from the fair value of the reporting unit. If the book value of goodwill is greater than its implied fair value, the Company writes down goodwill to its implied fair value. As described in Note 5, during the three months ended March 31, 2005, the Company’s Product Rights was deemed fully impaired based on the Company terminating the marketing and sales of dietary supplements and therefore the asset is not expected to be recoverable from the use or eventual disposition of the asset.

2. Related Party Transactions:

An entity controlled by the Chief Executive Officer (who is also the largest stockholder of NNBP), has loaned NNBP approximately $3.7 million as of March 31, 2006. These loans bear interest at the rate of 5% per annum and are due on demand. Interest expense for the above loans for the three months ended March 31, 2006 was approximately $38,000.

In March 2006, the Company assigned certain products to a related entity owned by the Company’s primary stockholder for no compensation (Note 3).

NANOBAC PHARMACEUTICALS, INCORPORATED AND SUBSIDIARIES

NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

THREE MONTHS ENDED MARCH 31, 2006

(UNAUDITED)

3. Discontinuance of sale of supplements

During March 2006, the Company’s management established a plan for Nanobac to discontinue the sale of dietary supplements and the Company’s focus to be exclusively on the science that will ultimately lead to drug discovery and the development of diagnostic products. Effective March 30, the Company assigned these product rights to an entity owned by the primary stockholder for no compensation. As a result of the above decision, a charge to earnings of $585,000 for the impairment of the product rights intangible asset has been recognized in operating expenses in the accompanying March 31, 2006 condensed consolidated statement of operations.

4. Abandonment of lease

During March 2006, the Company ceased occupying certain leased office space in Tampa, Florida. As a result of the early abandonment of this office lease, a charge to earnings of approximately $125,000 for the write-off of leasehold improvements and the acceleration of lease payments associated with the abandoned lease has been recognized in operating expenses in the accompanying March 31, 2006 condensed consolidated statement of operations.

Item 2: Management's Discussion and Analysis of Financial Condition and Results of Operations

Business

Nanobac Pharmaceuticals, Inc. and its subsidiaries (which may be referred to as “Nanobac”, “the Company”, “NNBP”, “we”, “us” or “our”) is a life science company dedicated to the discovery and developments of products and services to improve people's health through the detection and treatment of Calcifying Nano-Particles (“CNPs”), otherwise known as "nanobacteria". The Company's pioneering research is establishing the pathogenic role of nanobacteria in soft tissue calcification, particularly in coronary artery heart disease, prostatitis and vascular disease.

Nanobac manufactures and markets In Vitro Diagnostic (IVD) kits and reagents for the detection of Calcifying Nano-Particles. IVD products include the NANOCAPTURE(TM) and NANO-SERO(TM) ELISA assays and the Nano-Vision(TM) line of antibodies and reagents. Nanobac's BioAnalytical Services works with biopharmaceutical partners to develop and apply methods for avoiding, detecting, and inactivating or eliminating CNPs from raw materials. Nanobac's drug discovery and development efforts are focused on developing new and existing compounds that effectively inhibit, destroy or neutralize CNPs.

We believe that calcification is a significant feature in most diseases that are leading causes of death, including heart disease. Calcification is shown in numerous studies to block circulation, cause inflammation and cell disruption, and is a possible sign of cancers. We have decided to have a sharpened focus on drug therapy based on findings by Nanobac scientists that certain drugs, when combined, are effective at halting the calcification process. Some of these drug combinations have not been tested in animals or humans. However, the Company has an advantage in that each of these drugs on its own has an FDA-approved record of being safe, therefore regulatory hurdles are significantly lower in every national jurisdiction.

Our plan is to focus on the following priorities over the next 12-18 months:

Therapy - We are entering into agreements to test our proprietary drug combinations to treat stone-forming diseases, with a preliminary focus on prostatitis, which affects millions of men and currently is largely untreatable. We will also conduct tests with other stone forming diseases such as gallstones and kidney stones.

Infection - The gold standard for proving that something is infectious is Koch's postulates. We intend to validate earlier findings on Koch's postulates with calcifying nanoparticles in laboratory animals, including testing whether the infection can be prevented or treated with a proprietary drug combination.

Characterization - We have preliminary photographic and biochemical evidence that calcifying nanoparticles self-replicate in non-precipitating conditions, suggesting further that they have the ability to be infectious. We have designed an experiment with NASA to demonstrate this via time-lapse photography, using new microscopic technology developed in 2005.

·	Thrombosis - Thrombosis is the cause of death in most hemodialysis patients. We intend to validate findings that calcifying nanoparticles discovered in human blood provoke thrombosis and might be preventable.

·	Diagnostics - We believe that our proprietary Elisa antibody test uniquely recognizes calcifying nanoparticles known as nanobacteria, and plan to further validate the functionality of this diagnostic test.

Item 2: Management's Discussion and Analysis of Financial Condition and Results of Operations (continued)

We will continue optimizing our proprietary diagnostics, with a clear focus on developing effective therapies in cooperation with well-established partners including NASA, Mayo Clinic, Cleveland Clinic, and numerous other institutions. Once these experiments are completed, we will have a compelling and well-rounded scientific basis for the Company to move forward.

Current Developments- Dr. Benedict S. Maniscalco, M.D. joined Nanobac as Director of Clinical Research, Medical Director and member of the Board of Directors on March 29, 2006. Dr. Maniscaclo replaces Jan Egberts who resigned effective March 29, 2006.

During March 2006, we decided to terminate the marketing and selling of dietary supplements in order for the Company to focus exclusively on the science related to CNPs, which we plan to lead to drug discovery and the development of diagnostic products for the detection and treatment of Nanobacteria related diseases. Furniture and equipment related to the dietary supplements’ business were sold at book value to an entity controlled by our Chief executive Officer and largest shareholder.

Patents - We have filed applications for a number of patents, have been granted patents, and await prosecution of pending application in the US and International Stages.

Patent		General Subject Matter	Expiration Date
US 5,135,851	U.S.	-Method for the culture and detection of nanobacteria also known as calcifying nanoparticles (issued in 1992)	May 8, 2010
US 6,706,290 PCT/EP1999/004555	U.S. & International Application (PCT)	-Methods for the eradication of Nanobacteria from articles and animals using various novel combinations of systems, chemicals, compounds, drugs, prodrugs, supplements, etc. (issued in 2004)	Jul 6, 2018
	U.S. & PCT Applications Filed	-Methods and Compositions (combinations) for treating diseases characterized by pathological calcification (Filed in 2004)
	U.S. & PCT Applications Filed	-Methods and combinations of compositions including Bisphosphonates, chelators, and citrates (Filed in 2004)
	U.S.	-Methods for the treatment of disease associated with calcification and/or plaque formation (Filed in 2004)
	U.S. & PCT Application Filed	-Detection of antibodies against compositions of conformationally changed proteins comprising calcium binding protein hydroxy apatite complexes and novel in vitro test methods (Filed in 2005)
	U.S. & PCT Applications filed	-Methods and compositions to detect calcifying nanoparticles including the identification and quantification of proteins thereon and correlation to diseases thereof (Filed in 2005)

Item 2: Management's Discussion and Analysis of Financial Condition and Results of Operations (continued)

Patents (continued) - There can be no assurance that our patents or pending applications will afford legal protection against competitors or provide significant proprietary protection or competitive advantage. In addition, our patents or pending applications could be held invalid or unenforceable by a court, or infringed or circumvented by others, or others could obtain patents that we would need to license or circumvent. Competitors or potential competitors may have filed patent applications or received patents, and may obtain additional patents and proprietary rights relating to proteins, small molecules, compounds, or processes competitive with ours. Additionally, for certain of our product candidates, competitors, or potential competitors may claim that their existing or pending patents prevent us from commercializing such product candidates in certain territories. Further, when our patents expire, other companies could develop new competitive products to our products.

Trade secret protection for our unpatented confidential and proprietary information is important to us. To protect our trade secrets, we generally require our staff members, material consultants, scientific advisors, and parties to collaboration and licensing agreements to execute confidentiality agreements upon the commencement of employment, the consulting relationship, or the collaboration or licensing arrangement with us. However, others could either develop independently the same or similar information or obtain access to our information.

Change of Name - During April 2004, we announced a name change from Nanobac Pharmaceuticals, Incorporated to Nanobac Life Sciences, Inc. to become effective upon approval by the shareholders. No shareholder meeting was held to approve, therefore the name was not officially changed in the Florida records.

Results of Operations

The following table presents the percentage of period-over-period dollar change for the line items in our Condensed Consolidated Statements of Operations for the three month periods ended March 31, 2006 and 2005. These comparisons of financial results are not necessarily indicative of future results.

		Three months ended March
		2006	2005	% Change
Revenue		$161,286	$151,865	6%
Cost of revenue		45,195	43,838	3%
	Gross Profit	116,091	108,027	7%
	Gross Profit percentage	72%	71%

Selling, general and administrative		425,870	341,023	25%
Research and development		354,322	346,057	2%
Impairment loss on intangible asset		585,000	-
Depreciation and amortization		188,217	188,252	311%
	Operating loss	(1,437,318)	(767,305)	87%

Other income (Expense)		(50,369)	(738,616)	-93%

	Net loss	($1,487,687)	($1,505,921)	-1%

Item 2: Management's Discussion and Analysis of Financial Condition and Results of Operations (continued)

Revenue

Revenue for the three months ended March 31, 2006 and 2005 is summarized as follows:

	Three months ended March
	2006	2005

Nanobac Supplement	$120,293	$125,128
Observation Rights	6,000	0
Diagnostic Products	34,993	26,737

	$161,286	$151,865

During March 2006, we discontinued the sale of our dietary supplements. Accordingly, we expect no significant revenue from this revenue source in future periods.

Revenue from observation rights is being recognized over the agreement’s 12-month term using the straight-line method.

Cost of revenue

Cost of revenue consists of direct materials, testing services (for diagnostic products) and shipping. As a percentage of revenue, cost of revenue was 28% for the three months ended March 31, 2006 compared to approximately 29% for the three months ended March 31, 2005.

Selling, General and Administrative

Approximately two-thirds of selling, general and administrative (“SG&A”) expenses are comprised of payroll and professional fees. The majority of professional fees are related to public company expenses for audit, legal and investor relations. Other significant SG&A expenses include facility rental and insurance.

SG&A increased to $426,000 for the three months ended March 31, 2006 from $341,000 for the three months ended March 31, 2005. This increase is attributable to the abandoned lease described below offset by other net decreases in SG&A.

During March 2006, the Company ceased occupying certain leased office space in Tampa, Florida. As a result of the early abandonment of this office lease, a charge to earnings of approximately $106,000 for the acceleration of lease payments associated with the abandoned lease has been recognized in the accompanying condensed consolidated financial statements for the three months ended March 31, 2006.

Item 2: Management's Discussion and Analysis of Financial Condition and Results of Operations (continued)

Research and Development

For the three months ended March 31, 2006 and 2005 research and development (“R&D) expenses consisted of the following types of expenses:

	Three Months ended Mar 31
	2006	2005
U.S. Payroll and medical directors	52%	72%
Finland payroll and laboratory	31%	23%
Research studies	10%	2%
Other	7%	3%
	100%	100%

For the three months ended March 31, 2006, R&D expenses increased to $354,000 or by 2% compared to $346,000 for the three months ended March 31, 2005. With our renewed focus on R&D, we anticipate increasing R&D expenses during the next several months.

Impairment loss on intangible assets

During March 2006, the Company’s management established a plan for Nanobac to discontinue the sale of dietary supplements. As a result of the above decision, the product rights intangible asset was deemed to be fully impaired and an impairment loss on intangible assets of $585,000 has been recognized during the three months ended March 31, 2006.

Depreciation and amortization

Depreciation and amortization expense amounted to $188,000 for both the three months ended March 31, 2006 and 2005. Future amortization expense is expected to decrease as a result of the impairment loss on the product rights intangible asset recorded during the three months ended March 31, 2006.

Operating Loss

Our operating loss remained consistent at $1.5 million for both the three months ended March 31, 2006 and 2005. The 2006 loss includes a $106,000 charge for the abandonment of our Tampa lease and the $585,000 impairment loss on intangible assets.

Item 2: Management's Discussion and Analysis of Financial Condition and Results of Operations (continued)

Other income (expense)

Other income (expense) for the three months ended March 31, 2006 and 2005 is summarized as follows:

	Three months ended March
	2006	2005
Interest expense
Stockholder loan	($38,023)	($3,895)
Other	(216)	(1,298)
Loss on stock settlement obligation	-	(717,908)
Loss on disposition of assets	(18,330)	-
Foreign exchange gain (loss)	7,002	(10,717)
Other, net	(802)	(4,798)

Total	($50,369)	($738,616)

The shares issued in connection with the 2005 and 2004 Subscription Agreement transactions are financial instruments with characteristics of both liabilities and equity and as such have been presented in the accompanying condensed consolidated balance sheets as a liability. Changes in the liability are recorded as charges to the March 31, 2005 condensed consolidated statement of operations as a loss on the stock settlement obligation.

Loss on disposition of assets is attributable to the abandonment of our lease.

Foreign currency gain results from exchange rate changes between the U.S. dollar and the Euro on intercompany advances between our U.S. subsidiary and our Finland subsidiary.

Net Loss

We are experiencing significant losses as we conduct research and development related to nanobacteria. We believe it will take significant time before we will earn meaningful revenue to offset our expenses and there is no assurance that we will be able to accomplish this goal. As a result of the losses, we are dependent on affiliates of our CEO and other investors to provide sufficient cash sources to fund our operations.

Item 2: Management's Discussion and Analysis of Financial Condition and Results of Operations (continued)

Liquidity and Capital Resources

Since the United States Bankruptcy Court confirmed a plan of reorganization that allowed the Company to emerge from Chapter 11 during calendar 2002, the Company has financed its activities primarily through loans made by entities affiliated with our current Chief Executive Officer (referred to herein as “the Affiliated Entities”). These loans were made as funding was needed and were extremely advantageous to the Company in that the amounts were funded as the Company needed financial infusions and allowed the Company to avoid the costs and distractions of attempting to raise these amounts from unrelated parties. It is unrealistic to believe that unrelated parties would have offered terms as generous as those obtained from the Affiliated Entities, and it is also unlikely that any financing could have been obtained under any terms without the financing of the Affiliated Entities. From time to time the Affiliated Entities have agreed to allow a portion of the loan balances to be converted into shares of the Company’s common stock. There is no obligation on the part of the Affiliated Entities to make additional loans to the Company. The Affiliated Entities are also under no obligation to convert any portion of the loan balances owed to it into additional shares of the Company’s stock.

Since August of 2004, the Company has received $1.4 million (net of $125,000 of expenses) from three unaffiliated investors and one affiliate for shares of the Company’s stock and an equal amount of warrants to acquire additional shares of the Company’s stock. The exact number of shares to be issued is dependent upon the average closing bid price of the Company’s stock on the five trading days immediately prior to the date on which a registration statement for these shares is declared effective. The purchase price of the shares is equal to the lesser of (1) $.12 or (2) 52% of the average closing price described above. An additional $1.5 million is to be received from these investors within five days of registering the common shares and warrants. A registration statement has not yet been declared effective for these shares. Successful registration of the shares contemplated under the agreements discussed above will provide significant amounts of needed capital into the Company. However, there are no assurances that the SEC will declare a registration statement effective.

As of March 31, 2006, we had total assets of $8.7 million of which only $789,000 were current assets. At March 31, 2006, we had total current liabilities of $4.9 million and a working capital deficit of $4.1 million. $3.6 million of the $4.1 million working capital deficit is attributable to the related party loans from Affiliated Entities described above.

Net cash used in operations for the three months ended March 31, 2006 was $545,000. The negative cash flow from operations reflects the $1.5 million net loss for the period offset by non-cash charges of $585,000 due to impairment loss on intangible assets and $188,217 for depreciation and amortization and $106,000 for the abandonment of a lease (included in accrued expenses).

Net cash used by investing activities for the three months ended March 31, 2006 included $3,000 for the purchase of fixed assets, $3,000 for a security deposit offset by $6,000 of proceeds from the sale of property and equipment to affiliated entities at book value.

Net cash provided by financing activities for the three months ended March 31, 2006 was $1.2 million, which is attributable to stockholder loans.

As noted above, cash from stockholder loans financed our net loss and reduction of current liabilities. We are dependent on raising additional funding necessary to implement our business plan. Should we not be successful in raising cash from our CEO and other investors, we are unlikely to continue as a going concern.

Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations (continued)

Critical accounting policies

Use of estimates - The preparation of financial statements in conformity with accounting principles generally accepted in the United States of America requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosures of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenues and expenses during the reporting period. Actual results could differ from those estimates.

Forward Looking Statements

Our disclosure and analysis in this Form 10-QSB contains some forward-looking statements, within the meaning of the Private Securities Litigation Reform Act of 1995 (“the Act”), that set forth anticipated results based on our plans and assumptions. From time to time, we also provide forward-looking statements in other materials we release to the public as well as oral forward-looking statements. Such statements give our current expectations or forecasts of future events; they do not relate strictly to historical and current facts. We have tried wherever possible to identify such statements by using words such as “anticipate”, “estimate”, “expect”, “project”, “intend”, “plan”, “believe”, “will” and similar expressions in connection with any discussion of future operating or financial performance.

In light of the important factors that can materially affect results, including those set forth above and elsewhere in this report, the inclusion of forward-looking information herein should not be regarded as a representation by us or any other person that our objectives or plans will be achieved. We may encounter competitive, technological, financial and business challenges making it more difficult than expected to continue to market our products and services; competitive conditions within our industry may change adversely; we may be unable to retain existing key management and research personnel; our forecasts may not accurately anticipate market demand; and there may be other material adverse changes in our operations or business. Certain important factors affecting the forward looking statements made herein include, but are not limited to (i) accurately forecasting capital expenditures; (ii) obtaining new sources of external financing; (iii) serving as the nexus for nanobacteria research and (iv) conducting successful clinical trials supporting Dr. Kajander’s theories that the human body does not recognize nanobacteria as harmful, and accordingly, nanobacteria could be the cause of pathological disease causing calcification found in multiple diseases. Assumptions relating to budgeting, marketing, product development and other management decisions are subjective in many respects and thus susceptible to interpretations and periodic revisions based on actual experience and business developments, the impact of which may cause the Company to alter its capital expenditure or other budgets, which may in turn affect the Company's financial position and results of operations.

Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations (continued)

Quantitative and Qualitative Disclosures About Market Risk

While most of our operations are conducted in the United States, we also operate a laboratory in Kuopio Finland. We face two risks related to foreign currency exchange: translation risk and transaction risk. Amounts invested in our Finland operations are translated into US Dollars at the exchange rates in effect at the balance sheet date. Since the functional currency of our Finland subsidiary is the local currency, foreign currency translation of the balance sheet is reflected as a component of stockholders’ equity and does not impact operating results.

Our Finland subsidiary collects revenue and pays expenses in Euros, mitigating transaction risk. Revenues and expenses in Euros translate into varying amounts of US Dollars depending upon whether the US Dollar weakens or strengthens against the Euro. Therefore, changes in exchange rates may negatively affect the Company’s consolidated revenues and expenses (as expressed in US Dollars) from foreign operations.

Currency transaction gains or losses are incurred on our US Subsidiary’s intercompany advance to our Finland Subsidiary. We recognize a gain on the intercompany advance as the US Dollar weakens against the Euro and we recognize a loss when the US Dollar strengthens against the Euro.

The Company has not entered into a material amount of foreign currency forward exchange contracts or other derivative financial instruments to hedge the effects of adverse fluctuations in foreign currency exchange rates.

Item 3: Controls and Procedures

Disclosure controls and procedures

Under the supervision and with the participation of our management, including our Chief Executive Officer, we have evaluated the effectiveness of the design and operation of our disclosure controls and procedures within 90 days of the filing date of this report, and, based on this evaluation, our Chief Executive Officer has concluded that these controls and procedures are effective.

Disclosure controls and procedures are our controls and other procedures that are designed to ensure that information required to be disclosed by us in the reports we file or submit under the Exchange Act is recorded, processed, summarized and reported, within the time periods specified in the Securities and Exchange Commission's rules and forms. Disclosure controls and procedures include, without limitation, controls and procedures designed to ensure that information required to be disclosed by us in the reports that we file under the Exchange Act is accumulated and communicated to our management, including our principal executive officer and principal financial officer, as appropriate to allow timely decisions regarding required disclosure.

Item 3: Controls and Procedures (continued)

Section 404 of the Sarbanes-Oxley Act of 2002

Section 404 of the Sarbanes-Oxley Act of 2002 requires our report on Form 10-KSB for 2006 to include a report of management on internal control over financial reporting. Internal control over financial reporting, as defined under these rules, is a process designed to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles.

In our report, we will be required, among other things, to assess the effectiveness of our internal control over financial reporting. The report must also disclose any material weaknesses in internal control over financial reporting identified by management, and if there are any material weaknesses, we must conclude that our internal control over financial reporting was not effective. A material weakness, under the applicable rules, is a control deficiency, or combination of control deficiencies, that results in more than a remote likelihood that a material misstatement of the annual or interim financial statements will not be prevented or detected.

In conducting our ongoing assessment of its internal control over financial reporting to prepare for compliance with the requirements under Section 404 of the Sarbanes-Oxley Act, we have identified a lack of segregation of duties to be a potential material weakness in internal controls. Lack of segregation of duties is inherent to our company due to the small number of employees. Our assessment is still in process to determine if this situation is actually a material weakness or if there are any other material weaknesses.

Changes in internal controls

There were no significant changes in our internal controls or in other factors that could significantly affect these controls subsequent to the date of their evaluation.

PART II - OTHER INFORMATION

Item 1: Legal Proceedings

Except as described below, we know of no material, active or pending legal proceedings against us, nor are we involved as a plaintiff in any material proceedings or pending litigation. There are no proceedings in which any of our directors, officers or affiliates, or any registered or beneficial stockholders are an adverse party or has a material interest adverse to us.

On August 10, 2004, we were served with a civil action as filed in the Superior Court of Fulton County State of Georgia by Foltz Martin LLC and Openbook Learning Club, Inc. (“Foltz”). This suit alleges that the Company is liable for approximately $67,000 of liabilities plus approximately $11,000 interest for services performed by the plaintiffs for HealthCentrics, Inc. in 2003 and 2004. The Company owned 100% of HealthCentrics from December 2003 through March 2004 when HealthCentrics was sold by the Company to an affiliate. A judgment has been entered in the Superior Court of Fulton County, State of Georgia, in favor of Foltz in this matter. We do not believe that the Company is liable for the obligations of HealthCentrics and is currently starting the appeal process.

On January 19, 2006, we were served with a civil action as filed in the Superior Court of Fulton County State of Georgia by EliteCorp Atlanta, LLC (“EliteCorp”). This suit alleges that the Company is liable for approximately $318,000 of liabilities plus approximately $110,000 interest for services performed by the plaintiffs for HealthCentrics, Inc. in 2003 and 2004. We responded to this action on February 17, 2006 and denied virtually all the allegations of EliteCorp. We do not believe that the Company is liable for the obligations of HealthCentrics.

Item 2: Unregistered Sales of Equity Securities and Use of Proceeds

From August 2004 through February 2005, we executed Subscription Agreements with three unaffiliated investors and one affiliated investor. These investors paid us 50% of the subscription price at execution and the remaining 50% is due within five days from the date that a registration statement is declared effective for the common shares that are being issued. In exchange for the cash consideration, we are to issue these investors shares of our common stock equal to the amount paid divided by the lesser of (a) $0.12 or (b) fifty-two percent of the average closing bid price for our common stock for the five days immediately prior to the date on which a registration statement is declared effective (“The Fixed Price”). In addition, each of these investors will receive an equivalent number of warrants with expiration dates of five years from the date of issuance. One half of these warrants will be priced at 110% of the Fixed Price and the remainder will be priced at 150% of the Fixed Price. The minimum number of shares and warrants that will be issued under these Subscription Agreements (assuming a Fixed Price of $0.12 per share) is as follows:

		Number
		of Shares	Per Share	Proceeds
Common Stock:
	Unaffiliated Investors	16,250,000	$0.12	$1,950,000
	Affiliates	8,333,333	$0.12	$1,000,000
		24,583,333		$2,950,000

		Number	Exercise
		of Warrants	Price
Warrants:
	Unaffiliated Investors	8,125,000	$0.13
	Unaffiliated Investors	8,125,000	$0.18
	Affiliates	4,166,667	$0.13
	Affiliates	4,166,666	$0.18
		24,583,333

As of December 31, 2005, proceeds of $1,475,000 have been received and 12,297,667 unregistered shares had been issued under the above Subscription Agreements. The actual number of shares and warrants that ultimately will be issued under these Subscription Agreements may be substantially higher due to the variability of the Fixed Price. Based on our recent traded price of $0.04 to $0.09 per share, three to six times as many shares and warrants would be issued as described above. Further, if the Fixed Price is less than $0.09 per share, we do not have sufficient authorized shares to issue the common stock and warrants required under the above subscription agreements. Our stockholders need to approve any increase in our authorized shares.

Each of these investors received their shares in reliance upon Section 4(2) of the Securities Act of 1933, because each of the holders was knowledgeable, sophisticated and had access to comprehensive information about us. At all relevant times we were a reporting company under the Securities Exchange Act of 1934 and there was readily available adequate current public information with respect to the Company.

A success fee was awarded to a broker for one of the above unaffiliated investor transactions in the form of 5-year warrants equal to 20% of the value of the transaction. These warrants have exercise prices equal to $0.16 to $0.22 per share for transactions completed to date. Future warrants issued under this agreement will have an exercise price equal to NNBP’s stock price on the date of closing. We estimate that 2 million warrants will be issued to this broker.

Item 3: Defaults upon Senior Securities

None.

Item 4: Submission of Matters to a Vote of Security Holders

None.

Item 5: Other Information

None

Item 6: Exhibits and Reports on Form 8-K

(a) The following exhibits are filed as part of this report:

Exhibit 10.27 - Agreement with Calgenex Corporation

Exhibit 31.1 - Certification to Section 302 of the Sarbanes-Oxley Act of 2002 - Chief Executive Officer

Exhibit 31.2 - Certification to Section 302 of the Sarbanes-Oxley Act of 2002 - Chief Financial Officer

Exhibit 32.1 - Certification pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 - Chief Executive Officer

Exhibit 32.2 - Certification pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 - Chief Financial Officer

(b)	Reports on Form 8-K

On March 30, 2006, we filed Form 8-KSB to announce the addition of Dr. Benedict Maniscalco to our Board of Directors and the resignation of Dr. Jan Egberts from our Board of Directors.

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has caused this report to be signed on its behalf by the undersigned thereunto duly authorized.


Dated: May 8, 2006	NANOBAC PHARMACEUTICALS, INCORPORATED

		/s/ John D Stanton
		John D Stanton
		Chief Executive Officer

Nanobac Pharmaceuticals, Incorporated

EXHIBIT INDEX

EXHIBIT
NUMBER	DESCRIPTION	PAGE

10.27	Agreement with Calgenex Corporation	24

31.1	Certification to Section 302 of the Sarbanes-Oxley Act of 2002 - Chief Executive Officer	25

31.2	Certification to Section 302 of the Sarbanes-Oxley Act of 2002 - Chief Financial Officer	26

32.1	Certification pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 - Chief Executive Officer	27

32.2	Certification pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 - Chief Financial Officer	28